Target Information

Target General Infomation
Target ID
T55959
Former ID
TTDS00017
Target Name
Sodium-dependent dopamine transporter
Gene Name
SLC6A3
Synonyms
DA transporter; DAT; Dopamine transporter; SLC6A3
Target Type
Successful
Disease Attention deficit hyperactivity disorder [ICD9: 314; ICD10: F90]
Cocaine addiction [ICD9: 304.2; ICD10: F14.2]
Dementia [ICD9: 290-294; ICD10: F01-F07]
Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10: F32, F33, M32]
Mood disorder [ICD10: F30-F39]
Narcolepsy [ICD9: 347; ICD10: G47.4]
Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10: I21, I22, R52, R52.1-R52.2, R60.9, G89]
Obesity [ICD9: 278; ICD10: E66]
Parkinson's disease [ICD9: 332; ICD10: G20]
Traumatic brain injury [ICD9: 800.0-801.9, 803.0-804.9, 850.0-854.1; ICD10: S06]
Function
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
BioChemical Class
Neurotransmitter:sodium symporter
Target Validation
T55959
UniProt ID
Q01959
Sequence
MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDR
ETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL
GQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHC
NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQL
TACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSV
DFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSS
GFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGI
DSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAA
GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSI
VTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD
RELVDRGEVRQFTLRHWLKV
Drugs and Mode of Action
Drug(s) Altropane Drug Info Approved Attention deficit hyperactivity disorder [522203]
DEXMETHYLPHENIDATE HYDROCHLORIDE Drug Info Approved Attention deficit hyperactivity disorder [551871]
Ioflupane i-123 Drug Info Approved Parkinson's disease [531783]
Methylphenidate Drug Info Approved Attention deficit hyperactivity disorder [536713], [542252]
Modafinil Drug Info Approved Narcolepsy [551871]
Methylphenidate Drug Info Phase 4 Traumatic brain injury [536120], [542252]
Amitifadine Drug Info Phase 3 Obesity [527289], [528424]
Dasotraline Drug Info Phase 3 Mood disorder [524969], [543060]
NAV5001 Drug Info Phase 3 Dementia [524446]
Amfetamine transdermal Drug Info Phase 2 Attention deficit hyperactivity disorder [524098]
METHYLENEDIOXYMETHAMPHETAMINE Drug Info Phase 2 Discovery agent [521857]
GSK-1360707 Drug Info Phase 1 Major depressive disorder [523095]
RTI-336 Drug Info Phase 1 Cocaine addiction [536187]
Manifaxine Drug Info Discontinued in Phase 2 Major depressive disorder [546210]
NS-2389 Drug Info Discontinued in Phase 2 Major depressive disorder [546575]
SPD-473 Drug Info Discontinued in Phase 2 Mood disorder [546832]
KP106 Drug Info Discontinued in Phase 1 Attention deficit hyperactivity disorder [548965]
NSD-644 Drug Info Discontinued in Phase 1 Neurological disease [548670]
RG-7166 Drug Info Discontinued in Phase 1 Major depressive disorder [549027]
Vanoxerine Drug Info Discontinued in Phase 1 Cocaine addiction [536187]
Fluoratec Drug Info Terminated Attention deficit hyperactivity disorder [547430]
Seridopidine Drug Info Terminated Neurological disease [546992]
Inhibitor (+/-)-3-((naphthalen-2-yloxy)methyl)pyrrolidine Drug Info [530012]
(+/-)-threo-3',4'-Dichloromethylphenidate amide Drug Info [531163]
(+/-)-threo-3',4'-Dichlororitalinol Drug Info [531163]
(+/-)-threo-3',4'-Dichlororitalinol methyl ether Drug Info [531163]
(+/-)-threo-3',5'-Dichloromethylphenidate Drug Info [531163]
(+/-)-threo-3',5'-Dimethylmethylphenidate Drug Info [531163]
(+/-)-threo-3-Fluororitalinol Drug Info [531163]
(+/-)-threo-4'-Ethylmethylphenidate Drug Info [531163]
(+/-)-threo-Benzylphenidate Drug Info [531163]
(+/-)-threo-Methylphenidate amide Drug Info [531163]
(+/-)-threo-N-(2-Chlorobenzyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(2-Methylfuran)methylphenidate Drug Info [531163]
(+/-)-threo-N-(2-Methylpyridine)methylphenidate Drug Info [531163]
(+/-)-threo-N-(2-Methylthiopene)methylphenidate Drug Info [531163]
(+/-)-threo-N-(2-Phenylethyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(2-Phenylethyl)ritalinol Drug Info [531163]
(+/-)-threo-N-(3-Chlorobenzyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(3-Methylfuran)methylphenidate Drug Info [531163]
(+/-)-threo-N-(3-Methylpyridine)methylphenidate Drug Info [531163]
(+/-)-threo-N-(3-Methylthiopene)methylphenidate Drug Info [531163]
(+/-)-threo-N-(3-Phenylpropyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(3-Phenylpropyl)ritalinol Drug Info [531163]
(+/-)-threo-N-(4-Chlorobenzyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(4-Methoxybenzyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(4-Methylpyridine)methylphenidate Drug Info [531163]
(+/-)-threo-N-(4-Nitrobenzyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(4-Phenylbutyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(4-Phenylbutyl)ritalinol Drug Info [531163]
(+/-)-threo-N-(5-Phenylpentyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-(6-Phenylhexyl)methylphenidate Drug Info [531163]
(+/-)-threo-N-Allylmethylphenidate Drug Info [531163]
(+/-)-threo-N-Benzyl-3',4'-dichlororitalinol Drug Info [531163]
(+/-)-threo-N-Benzyl-3'-chloromethylphenidate Drug Info [531163]
(+/-)-threo-N-Benzylmethylphenidate amide Drug Info [531163]
(+/-)-threo-N-Ethylritalinol Drug Info [531163]
(+/-)-threo-N-Methyl-30-methylmethylphenidate Drug Info [531163]
(+/-)-threo-N-Propargylmethylphenidate Drug Info [531163]
(+/-)-threo-Ritalinol Drug Info [531163]
(+/-)-threo-Ritalinol methyl ether Drug Info [531163]
(1-Phenyl-ethyl)-(2-phenyl-quinazolin-4-yl)-amine Drug Info [535513]
(2R,3R)-iodoreboxetine Drug Info [529666]
(2R,3S)-2-[(2-Iodophenoxy)phenylmethyl]morpholine Drug Info [530282]
(2R,3S)-2-[(3-Iodophenoxy)phenylmethyl]morpholine Drug Info [530282]
(2R,3S)-2-[(4-Iodophenoxy)phenylmethyl]morpholine Drug Info [530282]
(2S,3S)-2-(m-Tolyl)-3,5,5-trimethylmorpholin-2-ol Drug Info [530946]
(2S,3S)-2-Phenyl-3,5,5-trimethylmorpholin-2-ol Drug Info [530946]
(2S,3S)-iodoreboxetine Drug Info [529666]
(cis)-1,6-diphenyl-3-aza-bicyclo[3.1.0]hexane Drug Info [529523]
(R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol Drug Info [530918]
(R)-3-(naphthalen-2-ylmethoxy)pyrrolidine Drug Info [530012]
(R)-DULOXETINE Drug Info [529824]
(R)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide Drug Info [530367]
(R)-Norfluoxetine Drug Info [529814]
(RS/SR)-2-[1-(3,4-dichlorophenyl)butyl]piperidine Drug Info [528619]
(RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine Drug Info [528619]
(RS/SR)-2-[1-(4-chlorophenyl)ethyl]piperidine Drug Info [528619]
(RS/SR)-2-[1-(4-chlorophenyl)hexyl]piperidine Drug Info [528619]
(RS/SR)-2-[1-(4-chlorophenyl)pentyl]piperidine Drug Info [528619]
(RS/SR)-2-[1-(4-chlorophenyl)propyl]piperidine Drug Info [528619]
(S)-3-(naphthalen-2-ylmethoxy)pyrrolidine Drug Info [530012]
(S)-Norfluoxetine Drug Info [529814]
1-(1,4-diphenylbutan-2-yl)piperazine Drug Info [528226]
1-(1-(4-FLUOROPHENYL)-2-(2-(TRIFLUOROMETHOXY)PHENYL)ETHYL)PIPERAZINE (ENANTIOMERIC MIX) Drug Info [530918]
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine Drug Info [529569]
1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane Drug Info [533891]
1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane Drug Info [533891]
1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane Drug Info [533891]
1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine Drug Info [530918]
1-(2,3-Dihydro-1H-indol-5-ylmethyl)-propylamine Drug Info [533479]
1-(2-(2-(DIFLUOROMETHOXY)PHENYL)-1-PHENYLETHYL)PIPERAZINE (ENANTIOMERIC MIX) Drug Info [530918]
1-(2-(2-chlorophenyl)-1-phenylethyl)piperazine Drug Info [528224]
1-(2-(2-methoxyphenyl)-1-phenylethyl)piperazine Drug Info [528224]
1-(2-(4-fluorophenoxy)phenyl)piperazine Drug Info [530474]
1-(2-(phenoxymethyl)phenyl)piperazine Drug Info [530474]
1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-(2-phenoxyphenyl)piperazine Drug Info [530474]
1-(3,4-Dichloro-phenyl)-3-diethylamino-indan-5-ol Drug Info [527062]
1-(3,4-Dichloro-phenyl)-3-methylamino-indan-5-ol Drug Info [527062]
1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane Drug Info [529523]
1-(3-bromophenyl)-2-(tert-butylamino)propan-1-one Drug Info [530728]
1-(3-chlorophenyl)-2-(dimethylamino)propan-1-one Drug Info [530728]
1-(3-chlorophenyl)-2-(piperidin-1-yl)propan-1-one Drug Info [530728]
1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [530137]
1-(4-bromophenyl)-2-(tert-butylamino)propan-1-one Drug Info [530728]
1-(4-bromophenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-(4-fluorophenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-(benzofuran-2-yl)-3-aza-bicyclo[3.1.0]hexane Drug Info [529523]
1-(naphthalen-2-yl)-3-aza-bicyclo[3.1.0]hexane Drug Info [529523]
1-(thiophen-2-yl)-3-aza-bicyclo[3.1.0]hexane Drug Info [529523]
1-Benzo[b]thiophen-2-yl-cycloheptylamine Drug Info [533891]
1-Benzo[b]thiophen-2-yl-cyclohexylamine Drug Info [533891]
1-Benzo[b]thiophen-2-yl-cyclopentylamine Drug Info [533891]
1-benzylpiperidine hydrochloride Drug Info [528826]
1-Biphenyl-4-yl-3-aza-bicyclo[3.1.0]hexane Drug Info [529523]
1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one Drug Info [528036]
1-phenyl-1-(piperidin-2-yl)propan-2-one Drug Info [528619]
1-phenyl-3-aza-bicyclo[3.1.0]hexane Drug Info [529523]
10R-hydroxylobel-7-ene Drug Info [528364]
10R-hydroxylobelane Drug Info [528364]
10S-hydroxylobel-7-ene Drug Info [528364]
10S-hydroxylobelane Drug Info [528364]
1S,2R-milnacipran Drug Info [529776]
2-((2-iodophenoxy)(phenyl)methyl)morpholine Drug Info [528517]
2-((3-iodophenyl)(o-tolyloxy)methyl)morpholine Drug Info [528517]
2-(2'-Aminoethyl)-5-benzyltetrahydrofuran Drug Info [529955]
2-(2,3-Dihydro-1H-indol-5-yl)-1-methyl-ethylamine Drug Info [533479]
2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine Drug Info [530596]
2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine Drug Info [530596]
2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran Drug Info [529955]
2-(Aminomethyl)-5-(2'-naphthyl)tetrahydrofuran Drug Info [529955]
2-(Aminomethyl)-5-phenethyltetrahydrofuran Drug Info [529955]
2-(N,N-Diethylamino)-3'-chloropropiophenone Drug Info [530442]
2-(N-Cyclopentylamino)-3'-bromopropiophenone Drug Info [530728]
2-(N-Cyclopentylamino)-3'-chloropropiophenone Drug Info [530442]
2-(N-Cyclopentylamino)-3'-fluoropropiophenone Drug Info [530728]
2-(N-Cyclopentylamino)-3'-methoxypropiophenone Drug Info [530728]
2-(N-Cyclopentylamino)-3'-methylpropiophenone Drug Info [530728]
2-(N-Cyclopropylamino)-3-chloropropiophenone Drug Info [530442]
2-(N-Isopropylamino)-3'-chloropropiophenone Drug Info [530442]
2-(N-Pyrrolidinyl)-3'-bromopropiophenone Drug Info [530728]
2-(N-Pyrrolidinyl)-3'-fluoropropiophenone Drug Info [530728]
2-(N-Pyrrolidinyl)-3'-methoxypropiophenone Drug Info [530728]
2-(N-Pyrrolidinyl)-3'-methylpropiophenone Drug Info [530728]
2-(N-Pyrrolidinyl)-3'-nitropropiophenone Drug Info [530728]
2-(N-tert-Butylamino)-3',4'-dichloropropiophenone Drug Info [530442]
2-(N-tert-Butylamino)-3'-chloroheptanophenone Drug Info [530442]
2-(N-tert-Butylamino)-3'-chlorohexanophenone Drug Info [530442]
2-(N-tert-Butylamino)-3'-chlorooctanophenone Drug Info [530442]
2-(N-tert-Butylamino)-3'-chloropentanophenone Drug Info [530442]
2-(N-tert-Butylamino)-4'-chloropropiophenone Drug Info [530442]
2-(N-tert-Butylamino)propiophenone Drug Info [530442]
2-(tert-butylamino)-1-(3-chlorophenyl)butan-1-one Drug Info [530728]
2-(tert-butylamino)-1-m-tolylpropan-1-one Drug Info [530728]
2-(tert-butylamino)-1-p-tolylpropan-1-one Drug Info [530728]
2-(tert-Butylamino)-3',4'-dichlorobutyrophenone Drug Info [530442]
2-(tert-Butylamino)-3',4'-dichloropentanophenone Drug Info [530442]
2-(tert-Butylamino)-3',5'-difluoropropiophenone Drug Info [530442]
2-(tert-Butylamino)-3'-fluoropropiophenone Drug Info [530442]
2-Amino-1-(4-methylthiophenyl)propane Drug Info [530347]
2-Aminomethyl-5-(p-bromophenyl)tetrahydrofuran Drug Info [529955]
2-Aminomethyl-5-(p-chlorophenyl)tetrahydrofuran Drug Info [529955]
2-Aminomethyl-5-(p-methoxyphenyl)tetrahydrofuran Drug Info [529955]
2-Aminomethyl-5-(p-t-butylphenyl)tetrahydrofuran Drug Info [529955]
2-Aminomethyl-5-(phenyl)tetrahydrofuran Drug Info [529955]
2-phenoxy-3-(piperidin-4-yl)pyridine Drug Info [530596]
2-phenylpiperidine hydrochloride Drug Info [528826]
2pyrrolidin-1-yl-1-phenylpentan-1-one Drug Info [528036]
3-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol Drug Info [528224]
3-(3,4-dichlorophenyl)-2-nortropene Drug Info [530502]
3-(4-Chlorophenyl)-2-nortropene Drug Info [530502]
3-(4-Fluorophenyl)-2-nortropene Drug Info [530502]
3-(4-Trifluoromethylphenyl)-2-nortropene Drug Info [530502]
3-alpha-Phenylmethoxy-3-beta-phenyl-nortropane Drug Info [530502]
3-p-Tolyl-8-aza-bicyclo[3.2.1]octane Drug Info [525906]
3-Phenyl-2-nortropene Drug Info [530502]
3alpha-(bis-chloro-phenylmethoxy)tropane Drug Info [528473]
4-(1H-indol-3-yl)-N,N-dimethylcyclohex-3-enamine Drug Info [528760]
4-(2-((3-fluorophenoxy)methyl)phenyl)piperidine Drug Info [530474]
4-(2-(2-fluoro-5-methylphenoxy)phenyl)piperidine Drug Info [530474]
4-(2-(2-fluorobenzyloxy)phenyl)piperidine Drug Info [530474]
4-(2-(3-chlorophenoxy)phenyl)piperidine Drug Info [530474]
4-(2-(3-fluorophenoxy)-4-methylphenyl)piperidine Drug Info [530474]
4-(2-(3-fluorophenoxy)phenyl)piperidine Drug Info [530474]
4-(2-(4-fluorobenzyloxy)phenyl)piperidine Drug Info [530474]
4-(2-(4-fluorophenoxy)-4-methylphenyl)piperidine Drug Info [530474]
4-(2-(4-fluorophenoxy)phenyl)piperidine Drug Info [530474]
4-(2-(benzyloxy)-3-fluorophenyl)piperidine Drug Info [530474]
4-(2-(benzyloxy)-6-fluorophenyl)piperidine Drug Info [530474]
4-(2-(benzyloxy)phenyl)piperidine Drug Info [530474]
4-(2-(phenoxymethyl)phenyl)piperidine Drug Info [530474]
4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine Drug Info [530596]
4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine Drug Info [530474]
4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine Drug Info [530474]
4-(2-fluoro-6-phenoxyphenyl)piperidine Drug Info [530474]
4-(2-phenoxyphenyl)piperidine Drug Info [530474]
4-(2-pyrrolidin-1-yl-pentanoyl)benzonitrile Drug Info [528036]
4-(3-fluoro-2-phenoxyphenyl)piperidine Drug Info [530474]
4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one Drug Info [531079]
6-(3-aza-bicyclo[3.1.0]hexan-1-yl)quinoline Drug Info [529523]
6-(piperidin-4-ylmethoxy)-2-naphthonitrile Drug Info [530012]
7-(piperidin-4-ylmethoxy)-2-naphthonitrile Drug Info [530012]
8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane Drug Info [525906]
8R-hydroxylobel-9-ene Drug Info [530601]
8R-hydroxylobelane Drug Info [528364]
8S-hydroxylobel-9-ene Drug Info [528364]
8S-hydroxylobelane Drug Info [528364]
Altropane Drug Info [534626]
Amfetamine transdermal Drug Info [531141]
AMINOBENZTROPINE Drug Info [534349]
Amitifadine Drug Info [543975]
ANOLOBINE Drug Info [551362]
ANONAINE Drug Info [551362]
ANTIOQUINE Drug Info [551362]
Benzhydryl-(2-phenyl-quinazolin-4-yl)-amine Drug Info [535513]
Benzyl-(2-phenyl-quinazolin-4-yl)-amine Drug Info [535513]
Bip-tyr(3bzl)-thr-pro-lys-thr Drug Info [528289]
Bip-tyr-ala-pro-lys-thr(obzl)-gly Drug Info [528289]
Bip-tyr-thr-ala-pro-phe Drug Info [528289]
Bip-tyr-thr-pro-ala-thr(obzl)-gly Drug Info [528289]
Bip-tyr-thr-pro-lys-thr Drug Info [528289]
Bip-tyr-thr-pro-lys-thr(obzl)-gly Drug Info [528289]
Bip-tyr-thr-pro-thr(obzl)-gly Drug Info [528289]
Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine Drug Info [529592]
Cis-3-phenoxy-2,3-dihydro-1H-inden-1-amine Drug Info [529530]
COCAINE.HCL Drug Info [528826]
COCLAURINE Drug Info [551362]
compound 58 Drug Info [532887]
D-166A Drug Info [529287]
D-211A Drug Info [529287]
D-211B Drug Info [529287]
D-254C Drug Info [529287]
D-257A Drug Info [529287]
D-257C Drug Info [529287]
Dasotraline Drug Info [533235]
DEXMETHYLPHENIDATE HYDROCHLORIDE Drug Info [528826]
DIFLUOROBENZTROPINE Drug Info [528473]
DIMETHYLGRISABINE Drug Info [551362]
Erythro-3,4-dichloromethylphenidate hydrochloride Drug Info [528826]
GB-12819 Drug Info [526396]
GSK-1360707 Drug Info [532361]
HOMOAROMOLINE Drug Info [551362]
ISOPILINE Drug Info [551362]
ISOTETRANDRINE Drug Info [551362]
Methyl 2-(naphthalen-2-yl)benzoate Drug Info [528794]
METHYLENEDIOXYAMPHETAMINE Drug Info [530914]
METHYLENEDIOXYMETHAMPHETAMINE Drug Info [530347]
N,Ndimethyl milnacipran Drug Info [529263]
N-Benzylmethylphenidate Drug Info [531163]
NISOXETINE Drug Info [529530]
NORBOLDINE Drug Info [551362]
NORSTEPHALAGINE Drug Info [551362]
O-2442 Drug Info [543975]
O-methyldauricine Drug Info [551362]
OBABERINE Drug Info [551362]
Para-chloroamphetamine Drug Info [530347]
PF-18298 Drug Info [530918]
PF-3409409 Drug Info [530265]
PF-526014 Drug Info [530918]
PSEUDOCOCAINE Drug Info [525537]
PYROVALERONE Drug Info [530137]
R-226161 Drug Info [528772]
R-NORDULOXETINE Drug Info [530368]
RG-7166 Drug Info [549028]
RTI-219 Drug Info [528932]
SECOCULARIDINE Drug Info [551362]
SPD-473 Drug Info [527287]
Threo-1-aza-5-phenyl[4.4.0]decane hydrochloride Drug Info [528826]
Threo-3,4-dichlororitalinol hydrochloride Drug Info [528826]
Threo-N-ethylritalinol hydrochloride Drug Info [528826]
Threo-ritalinol hydrochloride Drug Info [528826]
Threo-ritalinol methyl ether hydrochloride Drug Info [528826]
Trans-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine Drug Info [529530]
WIN-35065 Drug Info [528932]
WIN-35065-2 Drug Info [534240]
WIN-35066-2 Drug Info [527309]
WIN_35428 Drug Info [534240]
[3-(3,4-Dichloro-phenyl)-indan-1-yl]-methyl-amine Drug Info [527062]
[3H]GBR12935 Drug Info [533984]
[3H]WIN35428 Drug Info [533984]
[N-[2-[(3'-N'-PROPYL-3''ALPHA-(BIS(4-FLUORORPHENYL)METHOXY)TROPANE-2''BETA-CARBOXYLIC ACID METHYL ESTER)(2-MERCAPTOETHYL)AMINO]ACETYL]-2-AMINOETHANETHIOLATO]RHENIUM(V) OXIDE (DIASTEREOMERIC MIX) Drug Info [534407]
Modulator 3,4-Methylenedioxymethamphetamine Drug Info [551382]
Fluoratec Drug Info [534375]
Ioflupane i-123 Drug Info [551871]
Manifaxine Drug Info [527845]
MMDA Drug Info [551393]
Modafinil Drug Info [556264]
NAV5001 Drug Info [534626]
NS-2389 Drug Info [550007]
RTI-336 Drug Info
Seridopidine Drug Info [533284]
Antagonist 4-Methoxyamphetamine Drug Info [551380]
Agonist KP106 Drug Info [551554]
Blocker Methylphenidate Drug Info [536100]
Vanoxerine Drug Info [536187]
Activator NSD-644 Drug Info [550360]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
TEP EXP Info
Pathways
KEGG Pathway Dopaminergic synapse
Parkinson&#039
s disease
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Parkinson disease
Dopamine receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signaling
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Dopaminergic Neurogenesis
Parkinsons Disease Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Neurotransmitter Clearance In The Synaptic Cleft
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