Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W6WD
|
||||
| Former ID |
DNCL003070
|
||||
| Drug Name |
KP106
|
||||
| Indication | Attention deficit hyperactivity disorder [ICD9: 314; ICD10:F90] | Discontinued in Phase 1 | [1] | ||
| Company |
KemPharm
|
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| Target and Pathway | |||||
| Target(s) | Sodium-dependent dopamine transporter | Target Info | Agonist | [2] | |
| KEGG Pathway | Dopaminergic synapse | ||||
| Parkinson's disease | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| PANTHER Pathway | Adrenaline and noradrenaline biosynthesis | ||||
| Parkinson disease | |||||
| Dopamine receptor mediated signaling pathway | |||||
| Pathway Interaction Database | Alpha-synuclein signaling | ||||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | ||||
| WikiPathways | Monoamine Transport | ||||
| NRF2 pathway | |||||
| Dopaminergic Neurogenesis | |||||
| Parkinsons Disease Pathway | |||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | |||||
| Neurotransmitter Clearance In The Synaptic Cleft | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030892) | ||||
| REF 2 | Treating Attention-Deficit/Hyperactivity Disorder in Adults: Focus on Once-Daily Medications. Prim Care Companion CNS Disord 2011. | ||||
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