| References |
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| REF 1 |
Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell. 2003 Sep 19;114(6):715-25.
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| REF 2 |
Negative regulation of Lck by Cbl ubiquitin ligase. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3794-9.
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| REF 3 |
Loss of PRMT5 Promotes PDGFR Degradation during Oligodendrocyte Differentiation and Myelination. Dev Cell. 2018 Aug 20;46(4):426-440.e5.
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| REF 4 |
PP1 inhibitor induces degradation of RETMEN2A and RETMEN2B oncoproteins through proteosomal targeting. Cancer Res. 2003 May 1;63(9):2234-43.
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| REF 5 |
c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment. Cell Signal. 2010 Mar;22(3):377-85.
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| REF 6 |
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Sci Signal. 2015 Apr 28;8(374):ra40.
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| REF 7 |
Detection in primary chronic myeloid leukaemia cells of p210BCR-ABL1 in complexes with adaptor proteins CBL, CRKL, and GRB2. Genes Chromosomes Cancer. 2006 Dec;45(12):1121-9.
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| REF 8 |
The SH3 domain of Bruton's tyrosine kinase displays altered ligand binding properties when auto-phosphorylated in vitro. Eur J Immunol. 1999 Jul;29(7):2269-79.
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| REF 9 |
Shear Stress Regulates the Flk-1/Cbl/PI3K/NF-B Pathway Via Actin and Tyrosine Kinases. Cell Mol Bioeng. 2009 Sep 1;2(3):341-350.
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| REF 10 |
c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination. J Immunol. 2002 Oct 1;169(7):3793-800.
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| REF 11 |
Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL. J Cell Physiol. 1997 Apr;171(1):28-33.
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| REF 12 |
Somatic mutations lead to an oncogenic deletion of met in lung cancer. Cancer Res. 2006 Jan 1;66(1):283-9.
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| REF 13 |
Fgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils. Biochem J. 2003 Mar 1;370(Pt 2):687-94.
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| REF 14 |
c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Res. 2008 Nov 1;68(21):8761-9.
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| REF 15 |
c-Cbl, a ubiquitin E3 ligase that targets active -catenin: a novel layer of Wnt signaling regulation. J Biol Chem. 2013 Aug 9;288(32):23505-17.
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| REF 16 |
Charting the molecular network of the drug target Bcr-Abl. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7414-9.
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| REF 17 |
Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase. J Immunol. 2007 Aug 15;179(4):2397-407.
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| REF 18 |
C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus. Oncogene. 2002 Feb 7;21(7):1079-89.
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| REF 19 |
Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor. Oncogene. 2001 Jul 5;20(30):4058-69.
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| REF 20 |
Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b. Oncogene. 2004 Sep 16;23(42):7104-15.
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| REF 21 |
A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells. J Biol Chem. 1996 Sep 27;271(39):24063-8.
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| REF 22 |
The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor (PDGFR) Internalization and Signaling. J Biol Chem. 2016 May 27;291(22):11608-18.
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| REF 23 |
Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway. Traffic. 2008 Feb;9(2):251-66.
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| REF 24 |
The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase. Biochem Biophys Res Commun. 1999 Apr 2;257(1):129-38.
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| REF 25 |
Tyrosine-phosphorylated Cbl binds to Crk after T cell activation. J Immunol. 1996 Jul 1;157(1):110-6.
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| REF 26 |
Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b. Mol Cell. 2007 Aug 3;27(3):474-85.
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| REF 27 |
Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility. J Cell Biol. 2001 Jan 8;152(1):181-95.
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