Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| VEGFR2 --- TEK | methyl (6-(4-(2-(2-fluoro-5-(trifluoromethyl)phenylamino)-2-oxoethyl)phenoxy)-1H-benzoimidazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | methyl N-(6-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy) benzoxazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | 3-{10-carboximidoyl-5-oxo-14-propyl-4,14-diazapentacyclo[11.7.0.0^{2,6}.0^{7,12}.0^{15,20}]icosa-1(13),2(6),7(12),9,15,17,19-heptaen-18-yl}-1-(4-methylphenyl)urea | Drug Info |
| VEGFR2 --- TEK | rac-9-cyclohexyl-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | rac-9-(2-(diethylamino)ethyl)-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | (E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vinyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(2-(quinolin-3-yl)ethynyl)-N-(3-(trifluoromethyl)-phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | 3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}-1-(thiophen-2-yl)urea | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-morpholino-5-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | 6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | N-(3-isopropylphenyl)-4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)benzamide | Drug Info |
| VEGFR2 --- TEK | 1-(2-bromophenyl)-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}urea | Drug Info |
| VEGFR2 --- TEK | (S)-5-(2-(2-aminopyrimidin-5-yl)ethynyl)-2-fluoro-N-(2-(3-(methylamino)piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | methyl 5-(4-(3-(2-fluoro-5-(trifluoromethyl)phenyl)ureido)phenoxy)-1H-benzo[d]imidazol-2-ylcarbamate | Drug Info |
| VEGFR2 --- TEK | methyl N-(5-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)-3,4-diazaindole-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | 19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | N-(3-(4-amino-5-(biphenyl-4-yl)furo[2,3-d]pyrimidin-6-yl)phenyl)methanesulfonamide | Drug Info |
| VEGFR2 --- TEK | 3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}-1-[4-(methylsulfanyl)phenyl]urea | Drug Info |
| VEGFR2 --- TEK | 7-[(1E)-1-[(tert-butoxy)imino]ethyl]-19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | N-(6-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)benzthiazol-2-yl)methanesulfonamide | Drug Info |
| VEGFR2 --- TEK | 7-Cyclopentyl-6-methyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine | Drug Info |
| VEGFR2 --- TEK | 3-isopropyl-N-(3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | N-(2-((3-(dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)benzamide | Drug Info |
| VEGFR2 --- TEK | 1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl)phenyl)-3-(2-fluoro-6-(trifluoromethyl)phenyl)urea | Drug Info |
| VEGFR2 --- TEK | isopropyl 5-methyl-3-oxo-9-propyl-2,3,5,7,8,9-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-12-ylcarbamate | Drug Info |
| VEGFR2 --- TEK | 4-fluoro-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | 19-methyl-7-[(1E)-1-[(2-methylpropoxy)imino]ethyl]-3-(propan-2-yl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | 3-(2-(2-aminopyrimidin-5-yl)ethynyl)-N-(3-(trifluoromethyl)-phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | methyl N-(5-(4-((3-methylthiophenyl)aminocarbonylamino)-phenoxy)-1H-benzimidazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | 3-{3-ethyl-19-methyl-14-oxo-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}-1-(4-methoxyphenyl)urea | Drug Info |
| VEGFR2 --- TEK | N-(3-(4-amino-5-(4-methoxyphenyl)furo[2,3-d]pyrimidin-6-yl)phenyl)methanesulfonamide | Drug Info |
| VEGFR2 --- TEK | 1-(3-methoxyphenyl)-3-[19-methyl-3-(2-methylpropyl)-14-oxo-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl]urea | Drug Info |
| VEGFR2 --- TEK | 4-(Benzothiazol-6-ylamino)-6-(benzyl-isopropyl-amino)-[1,3,5]triazin-2-ol | Drug Info |
| VEGFR2 --- TEK | 4-Amino-7-cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid | Drug Info |
| VEGFR2 --- TEK | 9-(2-hydroxyethyl)-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | N-(3-(3-(dimethylamino)propyl)-5-(trifluoromethyl)phenyl)-4-methyl-3-(3-(pyrimidin-4-yl)pyridin-2-ylamino)benzamide | Drug Info |
| VEGFR2 --- TEK | CHEMBL526925 | Drug Info |
| VEGFR2 --- TEK | 4-methyl-N-phenyl-3-(3-(pyrimidin-4-yl)pyridin-2-ylamino)-benzamide | Drug Info |
| VEGFR2 --- TEK | GW673715X | Drug Info |
| VEGFR2 --- TEK | 3-butyl-7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | 5,6-bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-amine | Drug Info |
| VEGFR2 --- TEK | 3-(2-(2-aminopyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | methyl N-(5-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenylcarbonyl)-1H-benzimidazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | 7-[(furan-2-yl)carbonyl]-19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | (E/Z)-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- TEK | 7-[(furan-3-yl)carbonyl]-19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | N-(2-methoxy-5-(trifluoromethyl)phenyl)-4-methyl-3-(3-(pyrimidin-4-yl)pyridin-2-ylamino)benzamide | Drug Info |
| VEGFR2 --- TEK | CEP-7055 | Drug Info |
| VEGFR2 --- TEK | SID124349931 | Drug Info |
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