Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXFJ5H
|
||||
| Drug Name |
19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
|
||||
| Synonyms |
CHEMBL258437
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H16N4O
|
||||
| Canonical SMILES |
Cn1cc2c(CCc3c2c4C(=O)NCc4c5c6ccccc6[nH]c35)n1
|
||||
| InChI |
InChI=1S/C20H16N4O/c1-24-9-13-15(23-24)7-6-11-16(13)18-12(8-21-20(18)25)17-10-4-2-3-5-14(10)22-19(11)17/h2-5,9,22H,6-8H2,1H3,(H,21,25)
|
||||
| InChIKey |
GOPWMXCRSJOJRB-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.