Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXTX6H
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| Drug Name |
N-(3-(4-amino-5-(biphenyl-4-yl)furo[2,3-d]pyrimidin-6-yl)phenyl)methanesulfonamide
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| Synonyms |
CHEMBL196841
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H20N4O3S
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| Canonical SMILES |
CS(=O)(=O)Nc1cccc(c1)c2oc3ncnc(N)c3c2c4ccc(cc4)c5ccccc5
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| InChI |
InChI=1S/C25H20N4O3S/c1-33(30,31)29-20-9-5-8-19(14-20)23-21(22-24(26)27-15-28-25(22)32-23)18-12-10-17(11-13-18)16-6-3-2-4-7-16/h2-15,29H,1H3,(H2,26,27,28)
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| InChIKey |
YPTADYIVARXAPS-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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