Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXE8SR
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| Drug Name |
4-methyl-N-phenyl-3-(3-(pyrimidin-4-yl)pyridin-2-ylamino)-benzamide
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| Synonyms |
CHEMBL221121
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H19N5O
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| Canonical SMILES |
Cc1ccc(cc1Nc2ncccc2c3ccncn3)C(=O)Nc4ccccc4
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| InChI |
InChI=1S/C23H19N5O/c1-16-9-10-17(23(29)27-18-6-3-2-4-7-18)14-21(16)28-22-19(8-5-12-25-22)20-11-13-24-15-26-20/h2-15H,1H3,(H,25,28)(H,27,29)
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| InChIKey |
QJPWLLXUZHFJGQ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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