Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2A7T
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| Drug Name |
7-Cyclopentyl-6-methyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
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| Synonyms |
CHEMBL69868
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H24N4O
|
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| Canonical SMILES |
Cc1c(c2ccc(Oc3ccccc3)cc2)c4c(N)ncnc4n1C5CCCC5
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| InChI |
InChI=1S/C24H24N4O/c1-16-21(17-11-13-20(14-12-17)29-19-9-3-2-4-10-19)22-23(25)26-15-27-24(22)28(16)18-7-5-6-8-18/h2-4,9-15,18H,5-8H2,1H3,(H2,25,26,27)
|
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| InChIKey |
QDRHYWFULQVDMF-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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