Drug Information
| Drug General Information | |||||
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| Drug ID |
DXLR6X
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| Drug Name |
N-(2-((3-(dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)benzamide
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| Synonyms |
CHEMBL278965
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H33F3N8O2
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| Canonical SMILES |
CNc1ncnc(n1)c2cccnc2Oc3cc(ccc3C)C(=O)Nc4cc(ccc4N(C)CCCN(C)C)C(F)(F)F
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| InChI |
InChI=1S/C30H33F3N8O2/c1-19-9-10-20(16-25(19)43-28-22(8-6-13-35-28)26-36-18-37-29(34-2)39-26)27(42)38-23-17-21(30(31,32)33)11-12-24(23)41(5)15-7-14-40(3)4/h6,8-13,16-18H,7,14-15H2,1-5H3,(H,38,42)(H,34,36,37,39)
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| InChIKey |
TYDADJOKJRXQDT-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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