Drug Information
| Drug General Information | |||||
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| Drug ID |
DXM8VQ
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| Drug Name |
3-{10-carboximidoyl-5-oxo-14-propyl-4,14-diazapentacyclo[11.7.0.0^{2,6}.0^{7,12}.0^{15,20}]icosa-1(13),2(6),7(12),9,15,17,19-heptaen-18-yl}-1-(4-methylphenyl)urea
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| Synonyms |
CHEMBL387174
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H29N5O2
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| Canonical SMILES |
CCCn1c2ccc(NC(=O)Nc3ccc(C)cc3)cc2c4c5CNC(=O)c5c6CC=C(Cc6c14)C=N
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| InChI |
InChI=1S/C30H29N5O2/c1-3-12-35-25-11-9-20(34-30(37)33-19-7-4-17(2)5-8-19)14-23(25)26-24-16-32-29(36)27(24)21-10-6-18(15-31)13-22(21)28(26)35/h4-9,11,14-15,31H,3,10,12-13,16H2,1-2H3,(H,32,36)(H2,33,34,37)
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| InChIKey |
ACZUPBJBDZROIE-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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