Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2MWO
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| Drug Name |
methyl N-(5-(4-((3-methylthiophenyl)aminocarbonylamino)-phenoxy)-1H-benzimidazol-2-yl)carbamate
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| Synonyms |
CHEMBL244096
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H21N5O4S
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| Canonical SMILES |
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(SC)c4)cc3)cc2[nH]1
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| InChI |
InChI=1S/C23H21N5O4S/c1-31-23(30)28-21-26-19-11-10-17(13-20(19)27-21)32-16-8-6-14(7-9-16)24-22(29)25-15-4-3-5-18(12-15)33-2/h3-13H,1-2H3,(H2,24,25,29)(H2,26,27,28,30)
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| InChIKey |
LILVTHVLIRBXAU-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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