Drug Information
| Drug General Information | |||||
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| Drug ID |
DX2MCP
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| Drug Name |
isopropyl 5-methyl-3-oxo-9-propyl-2,3,5,7,8,9-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-12-ylcarbamate
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| Synonyms |
CHEMBL219492
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H29N5O3
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| Canonical SMILES |
CCCn1c2ccc(NC(=O)OC(C)C)cc2c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c13
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| InChI |
InChI=1S/C27H29N5O3/c1-5-10-32-21-9-6-15(29-27(34)35-14(2)3)11-17(21)23-18-12-28-26(33)24(18)22-16(25(23)32)7-8-20-19(22)13-31(4)30-20/h6,9,11,13-14H,5,7-8,10,12H2,1-4H3,(H,28,33)(H,29,34)
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| InChIKey |
OUAZADMJAQLGBI-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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