Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1FID
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| Drug Name |
N-(6-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)benzthiazol-2-yl)methanesulfonamide
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| Synonyms |
CHEMBL244300
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H16F4N4O4S2
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| Canonical SMILES |
CS(=O)(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2s1
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| InChI |
InChI=1S/C22H16F4N4O4S2/c1-36(32,33)30-21-29-17-9-7-15(11-19(17)35-21)34-14-5-3-13(4-6-14)27-20(31)28-18-10-12(22(24,25)26)2-8-16(18)23/h2-11H,1H3,(H,29,30)(H2,27,28,31)
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| InChIKey |
MVJOUDCJKKXKMC-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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