miRNA General Information
miRNA Mature ID hsa-miR-155-5p
miRNA Stemloop AC MI0000681
miRNA Stemloop ID hsa-mir-155
Sequence uuaaugcuaaucgugauaggggu
miRNA General Information
miRNA Mature ID hsa-miR-155-5p
miRNA Stemloop AC MI0000681
miRNA Stemloop ID hsa-mir-155
Sequence uuaaugcuaaucgugauagggguu
TTD Target(s) Regulated by This miRNA Angiotensin II receptor type-1 (AGTR1) Successful Target Target Info [1]
Interleukin-8 (IL8) Successful Target Target Info [2]
Intercellular adhesion molecule ICAM-1 (ICAM1) Successful Target Target Info [3]
Interleukin-2 (IL2) Successful Target Target Info [4]
Thyroid hormone receptor beta (THRB) Successful Target Target Info [5]
Vascular endothelial growth factor receptor 1 (FLT-1) Successful Target Target Info [6]
Nitric-oxide synthase endothelial (NOS3) Clinical trial Target Target Info [7]
Stress-activated protein kinase 2a (p38 alpha) Clinical trial Target Target Info [8]
Wee1-like protein kinase (WEE1) Clinical trial Target Target Info [9]
Caspase-3 (CASP3) Clinical trial Target Target Info [10]
SH2 domain inositol 5'-phosphatase 1 (INPP5D) Clinical trial Target Target Info [11]
E-selectin (SELE) Clinical trial Target Target Info [3]
G1/S-specific cyclin-D1 (CCND1) Clinical trial Target Target Info [12]
Myosin light kinase (MYLK) Clinical trial Target Target Info [9]
T-cell-specific kinase (ITK) Clinical trial Target Target Info [4]
DNA-binding factor KBF1 (p105) Clinical trial Target Target Info [2]
Hypoxia-inducible factor 1 alpha (HIF-1A) Clinical trial Target Target Info [13]
Keratinocyte growth factor (FGF7) Clinical trial Target Target Info [14]
Colony stimulating factor-1 receptor (CSF-1R) Clinical trial Target Target Info [9]
Signal transducer and activator of transcription 1 (STAT1) Patented-recorded Target Target Info [15]
Myeloid differentiation primary response protein MyD88 (MYD88) Literature-reported Target Target Info [16]
Transcription regulator protein BACH1 (Bach1) Clinical trial Target Target Info [17]
von Hippel-Lindau disease tumor suppressor (VHL) Patented-recorded Target Target Info [18]
Transcription factor AP-1 (JUN) Discontinued Target Target Info [19]
Transforming protein RhoA (RHOA) Discontinued Target Target Info [20]
Lectin-like oxidized LDL receptor (OLR1) Clinical trial Target Target Info [2]
RNA-binding protein Musashi-2 (MSI2) Discontinued Target Target Info [14]
Mixed lineage kinase 2 (MAP3K10) Literature-reported Target Target Info [9]
cAMP-dependent protein kinase A type I (PRKAR1A) Literature-reported Target Target Info [9]
Oxysterols receptor LXR-alpha (NR1H3) Patented-recorded Target Target Info [21]
Phosphatase and tensin homolog (PTEN) Literature-reported Target Target Info [22]
Proto-oncogene c-Myc (MYC) Literature-reported Target Target Info [23]
Ras-related C3 botulinum toxin substrate 1 (RAC1) Literature-reported Target Target Info [9]
Casein kinase I alpha (CSNK1A1) Clinical trial Target Target Info [14]
Matrix metalloproteinase-16 (MMP-16) Literature-reported Target Target Info [24]
Mitotic growth and transcription activator (BAF190A) Literature-reported Target Target Info [9]
PAK-2 protein kinase (PAK2) Literature-reported Target Target Info [9]
Protein kinase N2 (PKN2) Literature-reported Target Target Info [14]
Serine/threonine-protein kinase NIK (MAP3K14) Literature-reported Target Target Info [9]
Annexin A2 (ANXA2) Literature-reported Target Target Info [14]
CCAAT/enhancer binding protein beta (CEBPB) Literature-reported Target Target Info [25]
DNA repair protein RAD51 homolog 1 (RAD51) Clinical trial Target Target Info [26]
Endothelin-1 (EDN1) Literature-reported Target Target Info [27]
Histidine ammonia-lyase (HAL) Literature-reported Target Target Info [9]
Interleukin 13 receptor alpha-1 (IL13RA1) Literature-reported Target Target Info [28]
Lysine-specific demethylase 3A (KDM3A) Literature-reported Target Target Info [29]
Protein C-ets-1 (ETS1) Literature-reported Target Target Info [30]
Proto-oncogene c-Fos (c-Fos) Literature-reported Target Target Info [8]
Vascular cell adhesion protein 1 (VCAM1) Literature-reported Target Target Info [6]
Acetyl-CoA transporter (SLC33A1) Patented-recorded Target Target Info [9]
Cysteine-rich angiogenic inducer 61 (CYR61) Literature-reported Target Target Info [31]
DNA mismatch repair protein Mlh1 (MLH1) Literature-reported Target Target Info [32]
DNA mismatch repair protein MSH2 (MSH2) Literature-reported Target Target Info [32]
F-box and WD-40 domain protein 7 (Fbxw7) Literature-reported Target Target Info [33]
Homeobox protein Nkx-3.1 (NKX3-1) Literature-reported Target Target Info [9]
Methyl cpg binding protein 2 (MECP2) Clinical trial Target Target Info [34]
Pleiotrophin (PTN) Literature-reported Target Target Info [35]
Polybromo-1 (PBRM1) Literature-reported Target Target Info [14]
Telomeric repeat-binding factor 1 (TERF1) Literature-reported Target Target Info [36]
Transcription factor E2F2 (E2F2) Literature-reported Target Target Info [37]
Runt-related transcription factor 2 (RUNX2) Literature-reported Target Target Info [38]
SSX2-interacting protein (SSX2IP) Literature-reported Target Target Info [9]
Suppressor of cytokine signaling 1 (SOCS1) Literature-reported Target Target Info [39]
Suppressor of cytokine signaling 3 (SOCS3) Literature-reported Target Target Info [40]
Inhibitor of nuclear factor kappa-B kinase (IKK) Patented-recorded Target Target Info [41]
Mothers against decapentaplegic homolog 3 (SMAD3) Preclinical Target Target Info [42]
Protein(s) Regulated by This miRNA 14-3-3 protein zeta/delta Regulated Protein [9]
28S ribosomal protein S27, mitochondrial Regulated Protein [9]
39S ribosomal protein L18, mitochondrial Regulated Protein [9]
Actin-related protein 2 Regulated Protein [9]
Actin-related protein 2/3 complex subunit 3 Regulated Protein [9]
Adenomatous polyposis coli protein Regulated Protein [44]
ADP-ribosylation factor-like protein 15 Regulated Protein [9]
Anamorsin Regulated Protein [9]
Anaphase-promoting complex subunit 16 Regulated Protein [9]
Apoptotic protease-activating factor 1 Regulated Protein [9]
Arfaptin-1 Regulated Protein [9]
Armadillo repeat-containing protein 2 Regulated Protein [9]
Asparagine--tRNA ligase, cytoplasmic Regulated Protein [9]
Astrocytic phosphoprotein PEA-15 Regulated Protein [35]
AT-rich interactive domain-containing protein 2 Regulated Protein [25]
B-cell lymphoma 6 protein Regulated Protein [47]
Calcium-binding protein 39 Regulated Protein [9]
Calcium-regulated heat-stable protein 1 Regulated Protein [9]
cAMP-dependent protein kinase inhibitor alpha Regulated Protein [48]
Carbonyl reductase family member 4 Regulated Protein [9]
Caspase recruitment domain-containing protein 11 Regulated Protein [9]
Centrosomal protein of 41 kDa Regulated Protein [9]
Centrosomal protein of 83 kDa Regulated Protein [9]
Chromodomain-helicase-DNA-binding protein 9 Regulated Protein [9]
Claudin-1 Regulated Protein [49]
Clusterin-associated protein 1 Regulated Protein [9]
Coiled-coil domain-containing protein 82 Regulated Protein [9]
Cytochrome b-c1 complex subunit Rieske, mitochondrial Regulated Protein [50]
Cytochrome P450 2U1 Regulated Protein [9]
Cytoskeleton-associated protein 5 Regulated Protein [51]
DCN1-like protein 2 Regulated Protein [9]
Dedicator of cytokinesis protein 1 Regulated Protein [49]
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Regulated Protein [52]
DET1 homolog Regulated Protein [25]
DNA helicase MCM8 Regulated Protein [9]
DNA mismatch repair protein Msh6 Regulated Protein [32]
DNA polymerase epsilon subunit 3 Regulated Protein [9]
E3 ubiquitin-protein ligase RNF123 Regulated Protein [54]
E3 ubiquitin-protein ligase TRIM32 Regulated Protein [55]
Ethanolamine kinase 2 Regulated Protein [35]
Exosome complex component RRP4 Regulated Protein [9]
FAS-associated death domain protein Regulated Protein [56]
Forkhead box protein O3 Regulated Protein [57]
Friend leukemia integration 1 transcription factor Regulated Protein [30]
G1/S-specific cyclin-D2 Regulated Protein [59]
Gamma-aminobutyric acid receptor-associated protein-like 1 Regulated Protein [9]
GC-rich sequence DNA-binding factor 2 Regulated Protein [9]
Germinal center-associated signaling and motility protein Regulated Protein [60]
Glycine amidinotransferase, mitochondrial Regulated Protein [9]
Glycine amidinotransferase, mitochondrial Regulated Protein [14]
GTP-binding protein Rheb Regulated Protein [9]
Histone deacetylase complex subunit SAP30L Regulated Protein [9]
Histone-lysine N-methyltransferase NSD3 Regulated Protein [2]
HMG box-containing protein 1 Regulated Protein [9]
Homeobox and leucine zipper protein Homez Regulated Protein [63]
Homeobox protein cut-like 1 Regulated Protein [64]
Homeobox protein Meis1 Regulated Protein [30]
Immunoglobulin J chain Regulated Protein [9]
InaD-like protein Regulated Protein [65]
Integrator complex subunit 6 Regulated Protein [9]
Interferon gamma receptor 1 Regulated Protein [66]
Interleukin-17 receptor B Regulated Protein [9]
Kelch repeat and BTB domain-containing protein 2 Regulated Protein [9]
Kelch-like protein 5 Regulated Protein [9]
Leucine-rich repeat-containing protein 59 Regulated Protein [9]
Ligand of Numb protein X 2 Regulated Protein [9]
Ligand-dependent nuclear receptor corepressor-like protein Regulated Protein [9]
Ligand-dependent nuclear receptor-interacting factor 1 Regulated Protein [9]
Lysine-rich coiled-coil protein 1 Regulated Protein [9]
Macrosialin Regulated Protein [2]
MAGUK p55 subfamily member 5 Regulated Protein [9]
Matrin-3 Regulated Protein [17]
Max-interacting protein 1 Regulated Protein [68]
Meiosis regulator and mRNA stability factor 1 Regulated Protein [9]
Microphthalmia-associated transcription factor Regulated Protein [69]
Mitochondrial import inner membrane translocase subunit TIM14 Regulated Protein [9]
Mitochondrial import receptor subunit TOM20 homolog Regulated Protein [9]
Mitogen-activated protein kinase 13 Regulated Protein [70]
MORC family CW-type zinc finger protein 3 Regulated Protein [9]
Mothers against decapentaplegic homolog 2 Regulated Protein [42]
Mothers against decapentaplegic homolog 4 Regulated Protein [42]
Mothers against decapentaplegic homolog 5 Regulated Protein [25]
Muscleblind-like protein 3 Regulated Protein [9]
Myb-related protein A Regulated Protein [9]
Myocyte-specific enhancer factor 2A Regulated Protein [9]
Neuronal membrane glycoprotein M6-b Regulated Protein [72]
NFATC2-interacting protein Regulated Protein [17]
Pachytene checkpoint protein 2 homolog Regulated Protein [9]
Paladin Regulated Protein [9]
PC4 and SFRS1-interacting protein Regulated Protein [73]
PDZ and LIM domain protein 5 Regulated Protein [9]
Periplakin Regulated Protein [35]
PHD finger protein 14 Regulated Protein [9]
Phosphatidylinositide phosphatase SAC2 Regulated Protein [9]
Phosphatidylinositol 3-kinase regulatory subunit alpha Regulated Protein [74]
Phosphatidylinositol-binding clathrin assembly protein Regulated Protein [9]
Plastin-1 Regulated Protein [9]
Polyhomeotic-like protein 2 Regulated Protein [9]
PRA1 family protein 3 Regulated Protein [9]
Pre-mRNA-processing factor 17 Regulated Protein [9]
Probable ATP-dependent RNA helicase DHX40 Regulated Protein [9]
Probable E3 ubiquitin-protein ligase HERC4 Regulated Protein [9]
Protein argonaute-4 Regulated Protein [9]
Protein FAM135A Regulated Protein [30]
Protein FAM177A1 Regulated Protein [9]
Protein FAM199X Regulated Protein [9]
Protein FAM91A1 Regulated Protein [9]
Protein Jade-1 Regulated Protein [17]
Protein Jumonji Regulated Protein [37]
Protein KIBRA Regulated Protein [9]
Protein LDOC1 Regulated Protein [17]
Protein lin-7 homolog C Regulated Protein [9]
Protein sel-1 homolog 1 Regulated Protein [76]
Protocadherin-9 Regulated Protein [9]
Rab11 family-interacting protein 2 Regulated Protein [9]
Rap guanine nucleotide exchange factor 2 Regulated Protein [9]
RB-associated KRAB zinc finger protein Regulated Protein [9]
Regulator of nonsense transcripts 2 Regulated Protein [9]
Regulatory-associated protein of mTOR Regulated Protein [77]
RNA-binding protein Nova-1 Regulated Protein [9]
Selenocysteine insertion sequence-binding protein 2 Regulated Protein [9]
Serine/threonine-protein kinase greatwall Regulated Protein [14]
Serine/threonine-protein kinase WNK1 Regulated Protein [35]
SH3 and multiple ankyrin repeat domains protein 2 Regulated Protein [78]
SH3 and PX domain-containing protein 2A Regulated Protein [78]
Ski oncogene Regulated Protein [79]
Solute carrier family 35 member F2 Regulated Protein [9]
Suppressor of cytokine signaling 6 Regulated Protein [22]
Suppressor of cytokine signaling 6 Regulated Protein [81]
Syntenin-1 Regulated Protein [9]
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L Regulated Protein [9]
TBC1 domain family member 14 Regulated Protein [9]
TBC1 domain family member 8B Regulated Protein [9]
Teashirt homolog 3 Regulated Protein [82]
Tetraspanin-14 Regulated Protein [9]
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Regulated Protein [64]
Trafficking kinesin-binding protein 1 Regulated Protein [9]
Transcription factor 12 Regulated Protein [9]
Transcription factor A, mitochondrial Regulated Protein [83]
Transcription factor HIVEP2 Regulated Protein [25]
Transcription factor MafB Regulated Protein [78]
Transcription factor PU.1 Regulated Protein [84]
Transcription factor SOX-6 Regulated Protein [85]
Transcription termination factor 1 Regulated Protein [9]
Transducin-like enhancer protein 4 Regulated Protein [9]
Transforming growth factor beta regulator 1 Regulated Protein [63]
Transmembrane 6 superfamily member 1 Regulated Protein [17]
Tubulin-specific chaperone A Regulated Protein [9]
Tumor protein p53-inducible nuclear protein 1 Regulated Protein [86]
Twinfilin-1 Regulated Protein [35]
Ubiquilin-1 Regulated Protein [9]
Ubiquitin domain-containing protein 2 Regulated Protein [9]
Uncharacterized protein C17orf80 Regulated Protein [9]
Uncharacterized protein C3orf18 Regulated Protein [42]
Unconventional myosin-Id Regulated Protein [9]
Unconventional myosin-X Regulated Protein [38]
UPF0505 protein C16orf62 Regulated Protein [9]
Vacuolar protein sorting-associated protein 18 homolog Regulated Protein [9]
Vesicle transport protein GOT1B Regulated Protein [9]
WW domain binding protein 1-like Regulated Protein [9]
Zinc finger protein 248 Regulated Protein [9]
Zinc finger protein 254 Regulated Protein [9]
Zinc finger protein 28 Regulated Protein [9]
Zinc finger protein 431 Regulated Protein [35]
Zinc finger protein 493 Regulated Protein [9]
Zinc finger protein 561 Regulated Protein [9]
Zinc finger protein 611 Regulated Protein [9]
Zinc finger protein 652 Regulated Protein [25]
Zinc finger protein 714 Regulated Protein [35]
Zinc finger protein 83 Regulated Protein [9]
Zinc finger protein ZIC 3 Regulated Protein [25]
Zinc finger transcription factor Trps1 Regulated Protein [35]
References
REF 1 MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts. J Biol Chem. 2006 Jul 7;281(27):18277-84.
REF 2 MicroRNA-155 silencing enhances inflammatory response and lipid uptake in oxidized low-density lipoprotein-stimulated human THP-1 macrophages. J Investig Med. 2010 Dec;58(8):961-7.
REF 3 Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol. 2010 Jan 1;184(1):21-5.
REF 4 TGF- conditions intestinal T cells to express increased levels of miR-155, associated with down-regulation of IL-2 and itk mRNA. Mucosal Immunol. 2013 Jan;6(1):167-76.
REF 5 Epigenetic regulation of thyroid hormone receptor beta in renal cancer. PLoS One. 2014 May 21;9(5):e97624.
REF 6 Endothelial enriched microRNAs regulate angiotensin II-induced endothelial inflammation and migration. Atherosclerosis. 2011 Apr;215(2):286-93.
REF 7 Essential role of microRNA-155 in regulating endothelium-dependent vasorelaxation by targeting endothelial nitric oxide synthase. Hypertension. 2012 Dec;60(6):1407-14.
REF 8 Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer. Br J Cancer. 2013 Jul 23;109(2):452-61.
REF 9 Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq. RNA. 2010 Aug;16(8):1610-22.
REF 10 miR-155 targets Caspase-3 mRNA in activated macrophages. RNA Biol. 2016;13(1):43-58.
REF 11 Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7113-8.
REF 12 MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res. 2008 May;18(5):549-57.
REF 13 Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster. Cancer Res. 2008 Jul 15;68(14):5540-5.
REF 14 Widespread changes in protein synthesis induced by microRNAs.Nature. 2008 Sep 4;455(7209):58-63.
REF 15 The miR-124-p63 feedback loop modulates colorectal cancer growth. Oncotarget. 2017 Apr 25;8(17):29101-29115.
REF 16 Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation. FEBS Lett. 2010 Apr 16;584(8):1481-6.
REF 17 Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155. J Virol. 2007 Dec;81(23):12836-45.
REF 18 Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene. 2014 Feb 6;33(6):679-89.
REF 19 MiR-155 negatively regulates c-Jun expression at the post-transcriptional level in human dermal fibroblasts in vitro: implications in UVA irradiation-induced photoaging. Cell Physiol Biochem. 2012;29(3-4):331-40.
REF 20 MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol Cell Biol. 2008 Nov;28(22):6773-84.
REF 21 The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis. J Allergy Clin Immunol. 2017 Jun;139(6):1946-1956.
REF 22 MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN. Oncotarget. 2016 Dec 20;7(51):84508-84519.
REF 23 Downregulation of microRNA-155 accelerates cell growth and invasion by targeting c-myc in human gastric carcinoma cells. Oncol Rep. 2014 Sep;32(3):951-6.
REF 24 MiR-155 inhibits cell migration of human cardiomyocyte progenitor cells (hCMPCs) via targeting of MMP-16. J Cell Mol Med. 2012 Oct;16(10):2379-86.
REF 25 MicroRNA-155 is an Epstein-Barr virus-induced gene that modulates Epstein-Barr virus-regulated gene expression pathways. J Virol. 2008 Jun;82(11):5295-306.
REF 26 Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4536-41.
REF 27 Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothelial cells involves hypoxia-inducible factor-1alpha and microrNA-199. J Immunol. 2009 Oct 15;183(8):5232-43.
REF 28 The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor alpha1 (IL13Ralpha1). J Biol Chem. 2011 Jan 21;286(3):1786-94.
REF 29 Upregulation of MiR-155 in nasopharyngeal carcinoma is partly driven by LMP1 and LMP2A and downregulates a negative prognostic marker JMJD1A. PLoS One. 2011 Apr 26;6(4):e19137.
REF 30 MicroRNA 155 modulates megakaryopoiesis at progenitor and precursor level by targeting Ets-1 and Meis1 transcription factors. Br J Haematol. 2008 Nov;143(4):570-80.
REF 31 Physiological identification of human transcripts translationally regulated by a specific microRNA. Hum Mol Genet. 2005 Dec 15;14(24):3813-21.
REF 32 Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6982-7.
REF 33 Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by suppressing miR-155 expression and activating FBXW7 function. Am J Cancer Res. 2016 Nov 1;6(11):2561-2574.
REF 34 Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains. J Biol Chem. 2010 Jan 8;285(2):1529-43.
REF 35 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets. PLoS One. 2012;7(7):e40676.
REF 36 miR-155 drives telomere fragility in human breast cancer by targeting TRF1. Cancer Res. 2014 Aug 1;74(15):4145-56.
REF 37 Reticuloendotheliosis virus strain T induces miR-155, which targets JARID2 and promotes cell survival. J Virol. 2009 Dec;83(23):12009-17.
REF 38 MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation. J Virol. 2010 Jul;84(13):6318-27.
REF 39 MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12885-90.
REF 40 Borna disease virus encoded phosphoprotein inhibits host innate immunity by regulating miR-155. Antiviral Res. 2013 Apr;98(1):66-75.
REF 41 Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence. J Virol. 2008 Nov;82(21):10436-43.
REF 42 MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}. J Biol Chem. 2010 Dec 31;285(53):41328-36.
REF 43 Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq. RNA. 2010 Aug;16(8):1610-22.
REF 44 A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference.Nucleic Acids Res. 2009 Feb;37(3):e24.
REF 45 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets. PLoS One. 2012;7(7):e40676.
REF 46 MicroRNA-155 is an Epstein-Barr virus-induced gene that modulates Epstein-Barr virus-regulated gene expression pathways. J Virol. 2008 Jun;82(11):5295-306.
REF 47 MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages.J Clin Invest. 2012 Nov;122(11):4190-202.
REF 48 MicroRNA-155 is required for Mycobacterium bovis BCG-mediated apoptosis of macrophages.Mol Cell Biol. 2012 Jun;32(12):2239-53.
REF 49 MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. FASEB J. 2014 Jun;28(6):2551-65.
REF 50 MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1.J Cell Mol Med. 2011 Jul;15(7):1474-82.
REF 51 Quantitative proteomics identify novel miR-155 target proteins.PLoS One. 2011;6(7):e22146.
REF 52 Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a.J Neuroinflammation. 2015 Apr 8;12:66.
REF 53 Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6982-7.
REF 54 miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1. Blood. 2011 Apr 21;117(16):4293-303.
REF 55 Identification of putative pathogenic microRNA and its downstream targets in anaplastic lymphoma kinase-negative anaplastic large cell lymphoma. Hum Pathol. 2014 Oct;45(10):1995-2005.
REF 56 Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3.J Pathol. 2011 Oct;225(2):232-42.
REF 57 MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer.J Biol Chem. 2010 Jun 4;285(23):17869-79.
REF 58 MicroRNA 155 modulates megakaryopoiesis at progenitor and precursor level by targeting Ets-1 and Meis1 transcription factors. Br J Haematol. 2008 Nov;143(4):570-80.
REF 59 Overexpression of miR-155 promotes the proliferation and invasion of oral squamous carcinoma cells by regulating BCL6/cyclin D2.Int J Mol Med. 2016 May;37(5):1274-80.
REF 60 miR-155 regulates HGAL expression and increases lymphoma cell motility.Blood. 2012 Jan 12;119(2):513-20.
REF 61 Widespread changes in protein synthesis induced by microRNAs.Nature. 2008 Sep 4;455(7209):58-63.
REF 62 MicroRNA-155 silencing enhances inflammatory response and lipid uptake in oxidized low-density lipoprotein-stimulated human THP-1 macrophages. J Investig Med. 2010 Dec;58(8):961-7.
REF 63 Inhibition of the miR-155 target NIAM phenocopies the growth promoting effect of miR-155 in B-cell lymphoma.Oncotarget. 2016 Jan 19;7(3):2391-400.
REF 64 MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2735-40.
REF 65 The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.Nat Immunol. 2013 Jun;14(6):593-602.
REF 66 Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells.Eur J Immunol. 2010 Jan;40(1):225-31.
REF 67 Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155. J Virol. 2007 Dec;81(23):12836-45.
REF 68 MicroRNA-155 promotes glioma cell proliferation via the regulation of MXI1.PLoS One. 2013 Dec 23;8(12):e83055.
REF 69 Interferon--induced miR-155 inhibits osteoclast differentiation by targeting SOCS1 and MITF. FEBS Lett. 2012 Sep 21;586(19):3255-62.
REF 70 miR-155 Regulates Glioma Cells Invasion and Chemosensitivity by p38 Isforms In Vitro. J Cell Biochem. 2015 Jul;116(7):1213-21.
REF 71 MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}. J Biol Chem. 2010 Dec 31;285(53):41328-36.
REF 72 Marek's disease virus microRNA designated Mdv1-pre-miR-M4 targets both cellular and viral genes.Arch Virol. 2010 Nov;155(11):1823-37.
REF 73 A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages.PLoS Pathog. 2012 Sep;8(9):e1002937.
REF 74 Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma.Am J Pathol. 2012 Jul;181(1):26-33.
REF 75 Reticuloendotheliosis virus strain T induces miR-155, which targets JARID2 and promotes cell survival. J Virol. 2009 Dec;83(23):12009-17.
REF 76 Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma.Mol Carcinog. 2014 Sep;53(9):711-21.
REF 77 RPTOR, a novel target of miR-155, elicits a fibrotic phenotype of cystic fibrosis lung epithelium by upregulating CTGF.RNA Biol. 2016 Sep;13(9):837-47.
REF 78 LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas.Blood. 2012 Aug 23;120(8):1678-86.
REF 79 microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma.Nucleic Acids Res. 2011 Mar;39(5):1880-93.
REF 80 MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN. Oncotarget. 2016 Dec 20;7(51):84508-84519.
REF 81 MiRNA-155 mediates TAM resistance by modulating SOCS6-STAT3 signalling pathway in breast cancer. Am J Transl Res. 2015 Oct 15;7(10):2115-26.
REF 82 Hodgkin lymphoma cell lines are characterized by a specific miRNA expression profile. Neoplasia. 2009 Feb;11(2):167-76.
REF 83 Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM).Biochim Biophys Acta. 2015 Jul;1852(7):1420-7.
REF 84 MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN).J Biol Chem. 2009 Jun 12;284(24):16334-42.
REF 85 Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex-determining region Y box 6 in hepatocellular carcinoma.Cancer. 2012 May 1;118(9):2431-42.
REF 86 Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development.Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16170-5.
REF 87 MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation. J Virol. 2010 Jul;84(13):6318-27.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.