Target Information

Target General Infomation
Target ID
T76685
Former ID
TTDS00334
Target Name
Cannabinoid receptor 1
Gene Name
CNR1
Synonyms
CANN6; CB-R; CB1; Cannabinoid CB1 receptor; CNR1
Target Type
Successful
Disease Anorexia [ICD9: 307.1; ICD10: F50.0-F50.1]
Cerebrovascular ischaemia [ICD9: 434.91; ICD10: I61-I63]
Chemotherapy-induced nausea [ICD9: 787, 787.0; ICD10: R11]
Central nervous system disease [ICD10: G00-G99]
Diabetes; Obesity [ICD9: 250, 278; ICD10: E08-E13, E66]
Drug abuse [ICD9: 303-304; ICD10: F10-F19]
Endocrine disease [ICD10: E00-E35]
Hypertension; Diabetes; Obesity [ICD9: 250, 278, 401; ICD10: E08-E13, E66, I10-I16]
Insomnia [ICD9: 307.41, 307.42, 327.0, 780.51, 780.52; ICD10: F51.0, G47.0]
Ischemia [ICD9: 459.89; ICD10: I99.8]
Lipid metabolism disorder [ICD10: E75-E78]
Metabolic disorders [ICD9: 270-279; ICD10: E70-E89]
Nicotine dependence; Obesity [ICD9: 278, 305.1; ICD10: E66, F17]
Neuropathic pain [ICD9: 356.0, 356.8; ICD10: G64, G90.0]
Ovarian cancer [ICD9: 183; ICD10: C56]
Obesity [ICD9: 278; ICD10: E66]
Obesity; Metabolic disorders [ICD9: 270-279, 278; ICD10: E66, E70-E89]
Obesity; Diabetes [ICD9: 250, 278; ICD10: E08-E13, E66]
Psychotic disorders [ICD9: 290-299; ICD10: F20-F29]
Pain [ICD9: 338, 356.0, 356.8,780; ICD10: G64, G90.0, R52, G89]
Postherpetic neuralgia [ICD9: 53.19; ICD10: B02.2, G44.847, G53.0]
Schizophrenia [ICD9: 295; ICD10: F20]
Tobacco dependence [ICD9: 305.1; ICD10: F17]
Type 2 diabetes [ICD9: 250; ICD10: E11]
Function
Involved in cannabinoid-induced cns effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide.
BioChemical Class
GPCR rhodopsin
Target Validation
T76685
UniProt ID
P21554
Sequence
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Drugs and Mode of Action
Drug(s) Marinol Drug Info Approved Anorexia [538510]
NABILONE Drug Info Approved Insomnia [551871]
SR141716A Drug Info Approved Obesity [546366], [551871]
TETRAHYDROLIPSTATIN Drug Info Approved Obesity [545361], [551871]
Dronabinol oral solution Drug Info Phase 2/3 Chemotherapy-induced nausea [551036]
GW-42004 Drug Info Phase 2 Lipid metabolism disorder [549419]
SR-147778 Drug Info Phase 2 Obesity [521745]
Tebipenem Drug Info Phase 2 Nicotine dependence; Obesity [536122]
TM38837 Drug Info Phase 1 Obesity; Metabolic disorders [543260], [550186]
V-24343 Drug Info Phase 1 Type 2 diabetes [522402]
ZY01 Drug Info Phase 1 Obesity; Diabetes [551790]
CB1 antagonist, Bayer Drug Info Preclinical Obesity [536122]
JD-5037 Drug Info Preclinical Obesity; Diabetes [551059]
Rimonabant Drug Info Withdrawn from market Obesity [537145], [542474]
Rimonbant Drug Info Withdrawn from market Obesity [536710]
CP-945598 Drug Info Discontinued in Phase 3 Obesity [536122]
Taranabant Drug Info Discontinued in Phase 3 Obesity [537068]
AVE1625 Drug Info Discontinued in Phase 2 Psychotic disorders [547945]
AZD1940 Drug Info Discontinued in Phase 2 Pain [548585]
AZD2207 Drug Info Discontinued in Phase 2 Diabetes; Obesity [548462]
KDS-2000 Drug Info Discontinued in Phase 2 Postherpetic neuralgia [536374]
KN-38-7271 Drug Info Discontinued in Phase 2 Ischemia [547265]
SLV319 Drug Info Discontinued in Phase 2 Obesity [547594]
AZD1175 Drug Info Discontinued in Phase 1 Hypertension; Diabetes; Obesity [548277]
AZD1704 Drug Info Discontinued in Phase 1 Pain [548792]
CBD cannabis derivative Drug Info Discontinued in Phase 1 Schizophrenia [536463]
PF-514273 Drug Info Discontinued in Phase 1 Obesity [548445]
TAK-937 Drug Info Discontinued in Phase 1 Cerebrovascular ischaemia [548963]
Dianicline+rimonabant Drug Info Terminated Tobacco dependence [548622]
WIN-55212-2 Drug Info Terminated Discovery agent [542353], [545702]
Inhibitor (1R,2R)-N-Arachidonoylcyclopropanolamide Drug Info [530070]
(1R,2R)-N-Oleoylcyclopropanolamide Drug Info [530070]
(1R,2S)-N-Arachidonoylcyclopropanolamide Drug Info [530070]
(1R,2S)-N-Oleoylcyclopropanolamide Drug Info [530070]
(1S,2R)-N-Oleoylcyclopropanolamide Drug Info [530070]
(1S,2S)-N-Arachidonoylcyclopropanolamide Drug Info [530070]
(1S,2S)-N-Oleoylcyclopropanolamide Drug Info [530070]
(2R)-N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-2-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
(2R)-N-(7'-(2-CHLOROPHENYL)-6'-(4-CHLOROPHENYL)-3',4'-DIHYDROSPIRO[CYCLOHEXANE-1,2'-PYRANO[2,3-B]PYRIDINE]-4'-YL)-2-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
(2S)-N-(7'-(2-CHLOROPHENYL)-6'-(4-CHLOROPHENYL)-3',4'-DIHYDROSPIRO[CYCLOHEXANE-1,2'-PYRANO[2,3-B]PYRIDINE]-4'-YL)-2-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
(4-benzhydrylpiperazin-1-yl)(cyclohexyl)methanone Drug Info [530617]
(E)-N-(3,5-dimethoxyphenethyl)undec-2-enamide Drug Info [527788]
(E)-N-(4-methoxyphenethyl)undec-2-enamide Drug Info [527788]
(E)-N-(4-methoxyphenyl)undec-2-enamide Drug Info [527788]
1,3,5-triphenylimidazolidine-2,4-dione Drug Info [527995]
1,3,5-tris(4-chlorophenyl)imidazolidine-2,4-dione Drug Info [527995]
1,4-dihydroindeno[1,2-c]-pyrazole Drug Info [527858]
1,5-bis(4-chlorophenyl)-1H-1,2,3-triazole Drug Info [529882]
1-(2-morpholinoethyl)-1H-indol-3-yl acetate Drug Info [528907]
1-(4-CHLOROPHENYL)-2-(2,4-DICHLOROPHENYL)-5-(METHYLSULFINYL)-N-(PIPERIDIN-1-YL)-1H-IMIDAZOLE-4-CARBOXAMIDE (ENANTIOMERIC MIX) Drug Info [530827]
1-(bis(4-bromophenyl)methyl)-3-phenylurea Drug Info [527861]
1-(bis(4-chlorophenyl)methyl)-3-phenylurea Drug Info [527861]
1-[bis(4-bromophenyl)methyl]-3-phenylthiourea Drug Info [527861]
1-[bis(4-chlorophenyl)methyl]-3-(4-chlorophenyl)- Drug Info [527861]
1-[bis(4-chlorophenyl)methyl]-3-phenylthiourea Drug Info [527861]
1-[bis(4-iodophenyl)methyl]-3-(4-bromophenyl)urea Drug Info [527861]
2'-amino-4-(1,1-dimethyl-heptyl)-biphenyl-2-ol Drug Info [528844]
2-Benzylbenzo[f]chromen-3-one Drug Info [530009]
3'-amino-4-(1,1-dimethyl-heptyl)-biphenyl-2-ol Drug Info [528844]
3,4-diarylpyrazoline derivative Drug Info [527721]
3-Benzyl-5-isopropyl-8-methylchromen-2-one Drug Info [530009]
3-Benzyl-5-methoxy-7-methylchromen-2-one Drug Info [530009]
3-Benzyl-5-methoxychromen-2-one Drug Info [530009]
4'-amino-4-(1,1-dimethyl-heptyl)-biphenyl-2-ol Drug Info [528844]
4-(1,1-dimethyl-heptyl)-2'-methoxy-biphenyl-2-ol Drug Info [528844]
4-(1,1-dimethyl-heptyl)-3'-methoxy-biphenyl-2-ol Drug Info [528844]
4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one Drug Info [531079]
4-benzhydryl-N-butylpiperazine-1-carboxamide Drug Info [530617]
4-benzhydryl-N-cyclohexylpiperazine-1-carboxamide Drug Info [530617]
4-cyanophenyl ethyl dodecylphosphonate Drug Info [529659]
5-(1,1-dimethyl-heptyl)-2-pyridin-3-yl-phenol Drug Info [528844]
5-Biphenyl-4-ylmethyl-2-isobutyl-2H-tetrazole Drug Info [529434]
5-Methoxy-3-(2-methoxybenzyl)-2H-chromen-2-one Drug Info [530009]
6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDINE-4-CARBOXAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-N-((R)-1-HYDROXYETHYL)-1,2,2-TRIMETHYL-1,2,3,4-TETRAHYDRO-1,8-NAPHTHYRIDINE-4-CARBOXAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-N-(1-HYDROXY-2-METHYLPROPAN-2-YL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDINE-4-CARBOXAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-N-(HYDROXYMETHYL)-1,2,2-TRIMETHYL-1,2,3,4-TETRAHYDRO-1,8-NAPHTHYRIDINE-4-CARBOXAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
A-796260 Drug Info [530525]
AM-1241 Drug Info [530525]
AM-1710 Drug Info [529170]
AM-1714 Drug Info [529170]
AM-1715 Drug Info [529170]
AM-281 Drug Info [530009]
AM-404 Drug Info [534262]
AM-411 Drug Info [531004]
AM-4768 Drug Info [529170]
AM-630 Drug Info [529106]
Chlorphrifos oxon Drug Info [529659]
Cis-N-oleoylcyclopropanolamide Drug Info [530070]
CP-4497 Drug Info [531027]
CP-55940 Drug Info [530009]
DELTA 8-TETRAHYDROCANNOBINOL Drug Info [529727]
Dodecane-1-sulfonyl fluoride Drug Info [529659]
Isopropyl 4-nitrophenyl dodecylphosphonate Drug Info [529659]
Isopropyl dodecylfluorophosphonate Drug Info [529440]
JWH-120 Drug Info [529920]
JWH-133 Drug Info [531214]
JWH-145 Drug Info [528355]
JWH-146 Drug Info [528355]
JWH-147 Drug Info [528355]
JWH-150 Drug Info [528355]
JWH-156 Drug Info [528355]
JWH-229 Drug Info [529920]
JWH-243 Drug Info [528355]
JWH-244 Drug Info [528355]
JWH-245 Drug Info [528355]
JWH-246 Drug Info [528355]
JWH-268 Drug Info [529920]
JWH-292 Drug Info [528355]
JWH-293 Drug Info [528355]
JWH-297 Drug Info [529084]
JWH-307 Drug Info [528355]
JWH-308 Drug Info [528355]
JWH-309 Drug Info [528355]
JWH-324 Drug Info [531027]
JWH-325 Drug Info [529084]
JWH-337 Drug Info [529084]
JWH-342 Drug Info [529084]
JWH-344 Drug Info [529084]
JWH-345 Drug Info [529084]
JWH-346 Drug Info [528355]
JWH-347 Drug Info [528355]
JWH-348 Drug Info [528355]
JWH-363 Drug Info [528355]
JWH-364 Drug Info [528355]
JWH-365 Drug Info [528355]
JWH-366 Drug Info [528355]
JWH-367 Drug Info [528355]
JWH-368 Drug Info [528355]
JWH-369 Drug Info [528355]
JWH-370 Drug Info [528355]
JWH-371 Drug Info [528355]
JWH-372 Drug Info [528355]
JWH-373 Drug Info [528355]
JWH-385 Drug Info [529084]
JWH-392 Drug Info [529084]
JWH-401 Drug Info [529084]
JWH-402 Drug Info [529084]
JWH-403 Drug Info [529084]
JWH-404 Drug Info [529084]
JWH-405 Drug Info [529084]
JWH-406 Drug Info [529084]
JWH-407 Drug Info [529084]
JWH-440 Drug Info [531027]
JWH-442 Drug Info [531027]
KM-233 Drug Info [529515]
KM-233-M Drug Info [529515]
Methyl icosylphosphonofluoridate Drug Info [529659]
N-(1-adamantyl)-N'-propylsulfamide Drug Info [530389]
N-(1H-indazol-5-yl)icosa-5,8,11,14-tetraenamide Drug Info [529838]
N-(2,4-dimethoxyphenethyl)docos-13-enamide Drug Info [527788]
N-(2,4-dimethoxyphenethyl)oleamide Drug Info [527788]
N-(2-adamantyl)-N'-propylsulfamide Drug Info [530389]
N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide Drug Info [529106]
N-(3,3-Diphenyl)propyl-2,2-diphenylacetamide Drug Info [529563]
N-(3,3-Diphenyl)propyl-2-phenylacetamide Drug Info [529563]
N-(3,5-dimethoxyphenethyl)docos-13-enamide Drug Info [527788]
N-(3,5-dimethoxyphenethyl)oleamide Drug Info [527788]
N-(3-Phenyl)propyl-2,2-diphenylacetamide Drug Info [529563]
N-(3-Phenyl)propyl-2-(4-bromophenylacetamide) Drug Info [529563]
N-(4-hydroxybenzyl)icosa-5,8,11,14-tetraenamide Drug Info [529838]
N-(4-methoxybenzyl)oleamide Drug Info [527788]
N-(4-methoxyphenethyl)oleamide Drug Info [527788]
N-(4-methoxyphenyl)oleamide Drug Info [527788]
N-(4-morpholinophenyl)docos-13-enamide Drug Info [527788]
N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-2-HYDROXYACETAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-3-HYDROXY-2,2-DIMETHYLPROPANAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-3-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
N-(7'-(2-CHLOROPHENYL)-6'-(4-CHLOROPHENYL)-3',4'-DIHYDROSPIRO[CYCLOHEXANE-1,2'-PYRANO[2,3-B]PYRIDINE]-4'-YL)-2-HYDROXY-2-METHYLPROPANAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
N-(7-(2-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-2-HYDROXYACETAMIDE (ENANTIOMERIC MIX) Drug Info [530929]
N-(cis-9-cis-12-octadecadienyl)sulfamide Drug Info [530389]
N-arachidonoyl-N-(2-hydroxyethyl)hydroxylamine Drug Info [528112]
N-arachidonoyl-O-(2-hydroxyethyl)hydroxylamine Drug Info [528112]
N-ethyl-5,6-dip-tolylpyrazine-2-carboxamide Drug Info [528851]
N-isopentyl-5,6-dip-tolylpyrazine-2-carboxamide Drug Info [528851]
N-isopropyl-5,6-dip-tolylpyrazine-2-carboxamide Drug Info [528851]
N-methyl-5,6-dip-tolylpyrazine-2-carboxamide Drug Info [528851]
N-octadecyl-N'-propylsulfamide Drug Info [530389]
N-phenyl-5,6-dip-tolylpyrazine-2-carboxamide Drug Info [528851]
N-[6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDINE-4-YL]-4,4,4-TRIFLUORO-3-HYDROXYBUTANAMIDE (DIASTEREOMERIC MIX) Drug Info [530871]
NABILONE Drug Info [531196]
NAPHTHYRIDINONE Drug Info [530929]
O-arachidonoyl-N-(2-hydroxyethyl)hydroxylamine Drug Info [528112]
Octane-1-sulfonyl fluoride Drug Info [529659]
OLEOYLETHANOLAMIDE Drug Info [530070]
PARAOXON Drug Info [529659]
PRAVADOLINE Drug Info [551296]
Rac-cis-N-arachidonoylcyclopropanolamide Drug Info [530070]
Rac-trans-N-oleoylcyclopropanolamide Drug Info [530070]
SCH-356036 Drug Info [530597]
SEMIPLENAMIDE A Drug Info [526859]
SEMIPLENAMIDE B Drug Info [526859]
Semiplenamide G Drug Info [526859]
TETRAHYDROLIPSTATIN Drug Info [529733]
VER-156084 Drug Info [530200]
VER-156085 Drug Info [530200]
WIN-55212-2 Drug Info [530009]
{[(9Z)-octadec-9-en-1-yl]sulfamoyl}amine Drug Info [530389]
Agonist ACEA Drug Info [536731]
Anandamide Drug Info [537577]
arachidonyl-2-chloroethylamide Drug Info [525498]
arachidonylcyclopropylamide Drug Info [525498]
AZ-599 Drug Info [543877]
AZD1940 Drug Info [550288]
cannabinol Drug Info [534216]
Delta(9)-tetrahydrocannabinol Drug Info [537149]
Dianicline+rimonabant Drug Info [537145]
Dibenzothiazepines Drug Info [543877]
HU210 Drug Info [535946]
JD-5037 Drug Info [551059]
KDS-2000 Drug Info [536374]
Marinol Drug Info [537087]
MK-5596 Drug Info [543877]
O-1812 Drug Info [525966]
[3H]CP55940 Drug Info [534130]
[3H]HU-243 Drug Info [526736]
[3H]WIN55212-2 Drug Info [534535]
Antagonist AM251 Drug Info [535887]
AVE1625 Drug Info [549823]
AZD1175 Drug Info [550288]
AZD1704 Drug Info [550288]
AZD2207 Drug Info [550288], [551589]
BMS-812204 Drug Info [543877]
Cannabinoid 1 antagonists Drug Info [543877]
CB1 antagonist, Bayer Drug Info [536122]
CB1 antagonists Drug Info [543877]
CB1 antagonists Drug Info [543877]
CBD cannabis derivative Drug Info [536463]
compound 70 Drug Info [533285]
CP-945598 Drug Info [549974]
CXB-029 Drug Info [543877]
LY320135 Drug Info [534541]
Methanandamide Drug Info [537268]
Rimonabant Drug Info [536549], [536956], [537149]
Rimonbant Drug Info [536710]
SLV319 Drug Info [532030]
SR141716A Drug Info [535198], [535946]
Taranabant Drug Info [537149]
Tebipenem Drug Info [536122]
TM38837 Drug Info [550186]
V-24343 Drug Info [529987]
ZY01 Drug Info [551790]
[123I]AM251 Drug Info [534489]
Modulator Dronabinol oral solution Drug Info [1572591]
GW-42004 Drug Info
KN-38-7271 Drug Info
PF-514273 Drug Info [532853]
SR-147778 Drug Info
TAK-937 Drug Info [531715]
Modulator (allosteric modulator) Org27569 Drug Info [531899]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
TEP EXP Info
Pathways
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 521745ClinicalTrials.gov (NCT00239174) A Multicenter Study to Evaluate the Efficacy and Safety of of Four Doses of SR147778 in Obese Patients. U.S. National Institutes of Health.
Ref 522402ClinicalTrials.gov (NCT00734201) Safety and Efficacy of Low Doses of V24343 in Obese Subjects. U.S. National Institutes of Health.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536374Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26.
Ref 536463The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.
Ref 536710Anti-obesity drugs. Expert Opin Pharmacother. 2008 Jun;9(8):1339-50.
Ref 537068Obesity: pathophysiology and clinical management. Curr Med Chem. 2009;16(4):506-21.
Ref 537145Emerging drugs for the treatment of tobacco dependence. Expert Opin Emerg Drugs. 2009 Mar;14(1):23-32.
Ref 538510FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018651.
Ref 542353(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 733).
Ref 542474(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 745).
Ref 543260(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8705).
Ref 545361Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003007)
Ref 545702Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004262)
Ref 546366Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007737)
Ref 547265Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014615)
Ref 547594Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017654)
Ref 547945Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020616)
Ref 548277Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024090)
Ref 548445Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025584)
Ref 548462Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025707)
Ref 548585Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026807)
Ref 548622Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027143)
Ref 548792Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028889)
Ref 548963Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030875)
Ref 549419Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800036909)
Ref 5501862011 Pipeline of 7TM Pharma.
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