Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D06TGE
|
||||
Former ID |
DCL000327
|
||||
Drug Name |
Taranabant
|
||||
Synonyms |
Taranabant [USAN]; MK 0364; MK0364; MK-0364; MK-0634; Taranabant (INN/USAN); L]-2-methyl-2-[(5-(trifluoromethyl)pyridin-2-yl)oxy]propanamide; N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropy; N-(3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamide; N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide; N-((1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamide
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Obesity [ICD9: 278; ICD10:E66] | Discontinued in Phase 3 | [537068] | ||
Company |
Merck
|
||||
Structure |
Download2D MOL |
||||
Formula |
C27H25ClF3N3O2
|
||||
Canonical SMILES |
CC(C(CC1=CC=C(C=C1)Cl)C2=CC=CC(=C2)C#N)NC(=O)C(C)(C)OC3<br />=NC=C(C=C3)C(F)(F)F
|
||||
InChI |
1S/C27H25ClF3N3O2/c1-17(34-25(35)26(2,3)36-24-12-9-21(16-33-24)27(29,30)31)23(14-18-7-10-22(28)11-8-18)20-6-4-5-19(13-20)15-32/h4-13,16-17,23H,14H2,1-3H3,(H,34,35)/t17-,23+/m0/s1
|
||||
InChIKey |
QLYKJCMUNUWAGO-GAJHUEQPSA-N
|
||||
CAS Number |
CAS 701977-09-5
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
16309390, 23408060, 42305700, 50076997, 50086932, 57309658, 80708182, 96025692, 103504206, 104080908, 109692760, 126671461, 134338981, 135207455, 135343827, 137010390, 140904404, 152258058, 160646896, 172658609, 172919623, 184816678, 198978240, 198991966, 223592739, 223679364, 226644847, 241139588, 249125771, 252160245, 252215860, 252481191
|
||||
Target and Pathway | |||||
Target(s) | Cannabinoid receptor 1 | Target Info | Antagonist | [537149] | |
PANTHER Pathway | Endogenous cannabinoid signaling | ||||
Pathway Interaction Database | N-cadherin signaling events | ||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.