Drug Information

Drug General Information
Drug ID
D0B8EP
Former ID
DNC007321
Drug Name
1-[bis(4-chlorophenyl)methyl]-3-(4-chlorophenyl)-
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527861]
Structure
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2D MOL

3D MOL
Formula
C20H15Cl3N2O
Canonical SMILES
C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)NC(=O)NC3=CC=C(C=C3)Cl)Cl
InChI
1S/C20H15Cl3N2O/c21-15-5-1-13(2-6-15)19(14-3-7-16(22)8-4-14)25-20(26)24-18-11-9-17(23)10-12-18/h1-12,19H,(H2,24,25,26)
InChIKey
IQLQNNIZPSPERD-UHFFFAOYSA-N
PubChem Compound ID
11524275
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [527861]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 527861J Med Chem. 2005 Nov 17;48(23):7486-90.1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.
Ref 527861J Med Chem. 2005 Nov 17;48(23):7486-90.1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.

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