Drug General Information
Drug ID
D0F4BX
Former ID
DNC000746
Drug Name
HU210
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542332]
Structure
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2D MOL

3D MOL

Formula
C25H38O3
InChI
InChI=1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1
InChIKey
SSQJFGMEZBFMNV-WOJBJXKFSA-N
CAS Number
CAS 208265-92-3
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Agonist [535946]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 542332(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 731).
Ref 535946The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest. 2004 Apr;113(8):1202-9.

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