Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| VEGFR2 --- TEK | rac-9-isopropyl-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | propyl N-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}carbamate | Drug Info |
| VEGFR2 --- TEK | 7-acetyl-19-methyl-3-(propan-2-yl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | 1-(4-(4-amino-7-phenylfuro[3,2-c]pyridin-3-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea | Drug Info |
| VEGFR2 --- TEK | (S)-N-(2-(3-aminopiperidin-1-yl)-5-(trifluoromethyl)phenyl)-5-(2-(2-aminopyrimidin-5-yl)ethynyl)-2-fluorobenzamide | Drug Info |
| VEGFR2 --- TEK | N-(2-chloro-5-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)-3-isopropylbenzamide | Drug Info |
| VEGFR2 --- TEK | SID124349827 | Drug Info |
| VEGFR2 --- TEK | (E/Z)-4-(2-(6-phenyl-2,3-dihydroimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- TEK | 3-ethyl-19-methyl-7-[(thiophen-2-yl)carbonyl]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | rac-9-cyclopentyl-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | 19-methyl-3-(2-methylpropyl)-7-[(thiophen-2-yl)carbonyl]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | 3-(2-(6-aminopyridin-3-yl)ethynyl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | SID124349952 | Drug Info |
| VEGFR2 --- TEK | (R)-5-(2-(2-aminopyrimidin-5-yl)ethynyl)-N-(2-(3-(dimethylamino)pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-2-fluorobenzamide | Drug Info |
| VEGFR2 --- TEK | 4-fluorophenyl N-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}carbamate | Drug Info |
| VEGFR2 --- TEK | 1-(4-fluoro-3-(trifluoromethyl)phenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea | Drug Info |
| VEGFR2 --- TEK | methyl N-(5-(4-((3-(trifluoromethyl)phenyl)aminothiocarbonylamino)phenoxy)-1H-benzimidazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | methyl N-(5-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)-3a-aza-2-indolyl)carbamate | Drug Info |
| VEGFR2 --- TEK | 5-(2-(2-aminopyrimidin-5-yl)ethynyl)-N-(2-((3-(dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-2-fluorobenzamide | Drug Info |
| VEGFR2 --- TEK | 9-ethyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | N-(5-(4-((2-fluoro-5-(trifluoromethyl)-phenyl)aminocarbonylamino)phenoxy)-1H-benzimidazol-2-yl)-acetamide | Drug Info |
| VEGFR2 --- TEK | 2-amino-5-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)-1H-benzimidazole | Drug Info |
| VEGFR2 --- TEK | 4-methyl-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)-3-(3-(pyrimidin-4-yl)pyridin-2-yloxy)benzamide | Drug Info |
| VEGFR2 --- TEK | 9-isobutyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | 1-(4-(4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl)phenyl)-3-m-tolylurea | Drug Info |
| VEGFR2 --- TEK | rac-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(3-(pyrimidin-4-yl)pyridin-2-yloxy)-N-(4-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | 7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | 19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | 1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea | Drug Info |
| VEGFR2 --- TEK | SID124350139 | Drug Info |
| VEGFR2 --- TEK | 7-amino-19-methyl-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one | Drug Info |
| VEGFR2 --- TEK | 2-[4-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenoxy]-benzoic acid | Drug Info |
| VEGFR2 --- TEK | methyl N-(5-(5-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)-2-pyridyloxy)-1H-benzimidazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(3-(pyrimidin-4-yl)pyridin-2-ylamino)-N-(4-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | N-(4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- TEK | methyl (6-(4-(2-(2-fluoro-5-(trifluoromethyl)phenylamino)-2-oxoethyl)phenoxy)-1H-benzoimidazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | methyl N-(6-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy) benzoxazol-2-yl)carbamate | Drug Info |
| VEGFR2 --- TEK | 3-{10-carboximidoyl-5-oxo-14-propyl-4,14-diazapentacyclo[11.7.0.0^{2,6}.0^{7,12}.0^{15,20}]icosa-1(13),2(6),7(12),9,15,17,19-heptaen-18-yl}-1-(4-methylphenyl)urea | Drug Info |
| VEGFR2 --- TEK | rac-9-cyclohexyl-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | rac-9-(2-(diethylamino)ethyl)-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | (E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vinyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(2-(quinolin-3-yl)ethynyl)-N-(3-(trifluoromethyl)-phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | 3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}-1-(thiophen-2-yl)urea | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-morpholino-5-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | 6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one | Drug Info |
| VEGFR2 --- TEK | 4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- TEK | N-(3-isopropylphenyl)-4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)benzamide | Drug Info |
| VEGFR2 --- TEK | 1-(2-bromophenyl)-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}urea | Drug Info |
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