Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5VBL
|
||||
| Drug Name |
3-ethyl-19-methyl-7-[(thiophen-2-yl)carbonyl]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
|
||||
| Synonyms |
CHEMBL402531
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H22N4O2S
|
||||
| Canonical SMILES |
CCn1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c13)C(=O)c7cccs7
|
||||
| InChI |
InChI=1S/C27H22N4O2S/c1-3-31-20-9-6-14(26(32)21-5-4-10-34-21)11-16(20)23-17-12-28-27(33)24(17)22-15(25(23)31)7-8-19-18(22)13-30(2)29-19/h4-6,9-11,13H,3,7-8,12H2,1-2H3,(H,28,33)
|
||||
| InChIKey |
IDMQVBIPKRZHML-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.