Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T25258 | Target Info | |||
| Target Name | Multidrug resistance protein 1 (ABCB1) | ||||
| Synonyms |
PGY1; P-glycoprotein 1; P-gp; Pgp; MDR1; CD243 antigen; CD243; ATP-binding cassette sub-family B member 1
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| Target Type | Clinical trial Target | ||||
| Gene Name | ABCB1 | ||||
| Biochemical Class | ABC transporter | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 195 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Cimetidine
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Approved | Compound Info | ||
| Synonyms |
Acibilin; Acinil; Altramet; Brumetidina; Cimal; Cimetadine; Cimetag; Cimetidina; Cimetidinum; Cimetum; Dyspamet; Edalene; Eureceptor; Evicer; Gastrobitan; Gastromet; Histodil; Magicul; Metracin; Peptol; Sigmetadine; Tagamet; Tametin; Tratul; Ulcedin; Ulcedine; Ulcestop; Ulcimet; Ulcofalk; Ulcomedina; Ulcomet; Ulhys; Valmagen; Venopex; Ci metum; Cimetidine Hcl; Tagamet Hb; Biomet400; C 4522; FPF 1002; SKF 92334; Tagamet Hb 200; CIMETIDINE A/AB; Cimetidina [INN-Spanish]; Cimetidinum [INN-Latin]; DRG-0150; SKF-92334; Tagamet (TN); Tagamet HB (TN); Tagamet HB200 (TN); SK&F-92334; Cimetidine (JP15/USP/INN); Cimetidine [USAN:INN:BAN:JAN]; Tagamet, SKF-92334, Tratul, Tametin, Dyspamet, Acinil, Cimetidine; N-Cyano-N'-methyl-[2-[[[5-methyl-1H-imidazol-4-yl]methyl]thio]ethyl]guanidine; N''-Cyano-N-methyl-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine; N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine; N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidine; N-cyano-N'-methyl-N''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine; N-Cyano-N'-Methyl-N''-(2-(((5-Methyl-1H-Imidazol-4-YL)Methyl)Thio)Ethyl) Guanidine; N-Cyano-N'-methyl-N''-(2-(((5-methyl-1 H-imidazol-4-yl) methyl)thio)ethyl)guanidine; N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine; N''-cyano-N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)-ethyl)guanidine; 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine; 1-Cyano-2-methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]guanidine; 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine; 2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine; 2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine; 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine; 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
Digoxin
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Approved | Compound Info | ||
| Synonyms |
digoxin; 20830-75-5; 12beta-Hydroxydigitoxin; Digoxine; Lanoxin; Lanoxicaps; Digossina; Digoxina; Digoxinum; Digosin; Lanicor; Digacin; Dilanacin; CHEBI:4551; MLS000069819; Lanacordin; Cardiogoxin; Eudigox; Davoxin; SMR000059217; Rougoxin; Mapluxin; Lenoxin; Lanacrist; Dynamos; Vanoxin; Neo-Lanicor; Lanoxin PG; Digoxin Pediatric; Digoxin Nativelle; SK-Digoxin; UNII-73K4184T59; Homolle's digitalin; Hemigoxine Nativelle; MFCD00003674; Digitek (TN); Lanoxicaps (TN); Lanoxin (TN); Digoxin (JP15/USP); (3beta,5beta,12beta)-3-{[2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide; 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-5-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11,16-dihydroxy-2,15-dimethyltetracyclo[8700^{2,7}; [3H]digoxin
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
Erythromycin
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Approved | Compound Info | ||
| Synonyms |
Abboticin; Abomacetin; Acneryne; Acnesol; Aknemycin; Aknin; AustriaS; Benzamycin; Derimer; Deripil; Dotycin; Dumotrycin; ERY; ERYC; Emgel; Emuvin; Emycin; Endoeritrin; Erecin; Erisone; Eritomicina; Eritrocina; Eritromicina; Ermycin; Eros; Eryacne; Eryacnen; Erycen; Erycette; Erycin; Erycinum; Eryderm; Erydermer; Erygel; Eryhexal; Erymax; Erymed; Erysafe; Erytab; Erythro; Erythroderm; Erythrogran; Erythroguent; Erythromid; Erythromycine; Erythromycinum; Erytop; Erytrociclin; Ilocaps; Iloticina; Ilotycin; Inderm; IndermRetcin; Latotryd; Lederpax; Mephamycin; Mercina; Oftamolets; Paediathrocin; Pantoderm; Pantodrin; Pantomicina; Pharyngocin; Primacine; Propiocine; Proterytrin; Retcin; Robimycin; Romycin; Sansac; Staticin; Stiemicyn; Stiemycin; Tiloryth; Tiprocin; Torlamicina; Wemid; Akne Cordes Losung; Aknederm Ery Gel; Benzamycin Pak; ERYTHROMYCIN STEARATE; Eryc Sprinkles; Erythromycin A; Erythromycin Lactate; Erythromycin Ointment; Erythromycin base; Erythromycin intravenous; Erythromycin sodium lauryl sulfate; Inderm Gel; Oftalmolosa Cusi Eritromicina; Skid Gel E; Theramycin Z; Udima Ery Gel; E0751; Eryc 125; Erythromast 36; Ak-Mycin; Akne-Mycin; Del-Mycin; E-Base; E-Glades; E-Mycin; E-Solve 2; ERYC (base); Emu-V; Emu-Ve; Erimycin-T; Eritromicina [INN-Spanish]; Ery-B; Ery-Diolan; Ery-Sol; Ery-Tab; Ery-maxin; Eryc (TN); Eryc-125; Eryc-250; Erygel (TN); Erythra-Derm; Erythro-Statin; Erythro-Teva; Erythromycin & VRC3375; Erythromycine [INN-French]; Erythromycinum [INN-Latin]; Ilosone (TN); Ilosone (estolate); Ilotycin T.S; Kesso-Mycin; N-Methylerythromycin A; PCE Dispertab (base); Pce (TN); R-P Mycin; Sans-acne; Staticin (TN); T-Stat; Taimoxin-F; A/T/S; Akne-mycin (TN); C-Solve-2; E-Base (base); E-Mycin (base); Ery-Tab (base); Erythromycin [INN:BAN:JAN]; Ilotycin T.S.; T-stat (TN); E-mycin, Erycin, Robimysin; Erythromycin (JP15/USP/INN); Erythromycin, compd. with monododecyl sulfate, sodium salt; Sulfuric acid, monododecyl ester, sodium salt, compd. with erythromycin; Adecane-2,10-dione (non-preferred name); Erythromycin A, T-Stat, Pantomicina, HSDB 3074, Erytab, DRG-0279; Ery
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
Etoposide
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Approved | Compound Info | ||
| Synonyms |
etoposide; 33419-42-0; VePesid; Toposar; trans-Etoposide; Lastet; (-)-Etoposide; Zuyeyidal; Etoposidum; Etoposido; Vepesid J; Eposin; Etoposidum [INN-Latin]; Etoposide (VP16); VP 16-213; VP 16 (pharmaceutical); Etoposido [INN-Spanish]; Etopophos (phosphate salt); VP-16-213; 4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside; VP 16213; UNII-6PLQ3CP4P3; NK 171; NSC 141540; CCRIS 2392; HSDB 6517; 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside); EINECS 251-509-1; NSC-141540; Eposide; Etopol; Etosid; Vepeside; Demethyl EpipodophyllotoxinEthylidine Glucoside; E0675; Demethyl-epiodophyllotoxin ethylidene glucoside; Epipodophyllotoxin VP-16213; Eposin (TN); Etopophos (TN); Trans-Etoposide; VePESID (TN); Vepesid (TN); DEMETHY-EPIPODOPHYLLOTOXIN, ETHYLIDENE GLUCOSIDE; VP-16 (TN); Demethylepipodophyllotoxin-beta-D-ethylideneglucoside; Etoposide (JP15/USP/INN); Etoposide [USAN:INN:BAN:JAN]; Eposin, Vepesid, VP-16, Toposar, Etoposide; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI); Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside; 4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethylepipodophyllotoxin ethylidene-beta-D-glucoside; 4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin; 4-Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
Midazolam
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Approved | Compound Info | ||
| Synonyms |
Dazolam; Dormicum; Midanium; Midazolamum; Midosed; Versed; Midazolam Base; Dormicum (TN); Hypnovel (TN); Midacum (TN); Midazolamum [INN-Latin]; Ro 21-3981; Versed (TN); Midazolam (JAN/INN); Midazolam [INN:BAN:JAN]; 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate; 8-Chlor-6-(2-fluorphenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepin; 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine; 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride; 8-Chloro-6-(O-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]-benzodiazepine; 8-Chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
Vinblastine
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Approved | Compound Info | ||
| Synonyms |
Nincaluicolflastine; Rozevin; VLB; Vinblastin; Vinblastina; Vinblastinum; Vincaleucoblastin; Vincaleucoblastine; Vincaleukoblastine; Vincoblastine; Vinblastina [DCIT]; VR-8; Vinblastina (TN); Vinblastine (INN); Vinblastine [INN:BAN]; Vinblastinum [INN-Latin]; NDC 0002-1452-01; (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE; (2xi,3beta,4'beta,19xi)-vincaleukoblastine; 1H-Indolizino(8,1-cd)carbazole-5-carboxylic acid
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
Morphine
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Approved | Compound Info | ||
| Synonyms |
Avinza; Kadian; Morphine Sulfate; Depodur; Astramorph Pf; Duramorph Pf; Infumorph; Ms Contin; Oramorph Sr
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
Verapamil
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Approved | Compound Info | ||
| Synonyms |
Arpamyl; Calan; Calcan; Cordilox; Dexverapamil; Dilacoran; Drosteakard; Iproveratril; Isoptimo; Isoptin; Isotopin; Vasolan; Veracim; Verapamilo; Verapamilum; Veraptin; Verexamil; Bosoptin (TN); Calan (TN); D-365; Isoptin (TN); Verapamilo [INN-Spanish]; Verapamilum [INN-Latin]; Verelan (TN); CP-16533-1; Covera-HS (TN); Verapamil (USAN/INN); Verapamil [USAN:BAN:INN]; Verapamil [USAN:INN:BAN]; Alpha-((N-Methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile; Alpha-Isopropyl-alpha-((N-methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile; Alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)-methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile; (+-)-Verapamil; (+/-)-VERAPAMIL; (1)-3-(3,4-Dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile; 2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-(1-methylethyl) pentanenitrile; 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile; 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile; 5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile; 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile; Verapamil (Na-Ca chanel blocker)
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| Activity |
IC50 = 53000 nM
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[2] | |||
| Compound Name |
Ketoconazole
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Approved | Compound Info | ||
| Synonyms |
KCZ; KTZ; K 1003; R 41400; R41400; KS-1205; KW-1414; Perkhotal (TN); R 41,400; R-41400; R41,400; Ketoconazole [USAN:INN:BAN:JAN]; Nizoral, Extina, Xolegel, Kuric, Ketoconazole; Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; Cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; CIS-1-ACETYL-4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL)METHOXY)PHENYL)PIPERAZINE; (+-)-cis-1-Acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine; (+/-)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine; (+/-)-cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone; 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
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| Activity |
IC50 = 53400 nM
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[3] | |||
| Compound Name |
Miconazole
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Approved | Compound Info | ||
| Synonyms |
Dactarin; MCZ; Miconazol; Miconazolo; Miconazolum; Micozole; Minostate; Monistat; Vusion; Zimycan; Daktarin IV; Miconasil Nitrate; Miconazole nitrate salt; Miconazolo [DCIT]; Monistat IV; MJR 1762; Miconazole 3; Miconazole 3 Combination Pack; Miconazole 7 Combination Pack; Monazole 7; Monistat 1 Combination Pack; Monistat 3 Vaginal Ovules; Monistat 5 Tampon; Monistat 7 Vaginal Suppositories; R 18134; Aflorix(nitrate); Albistat(nitrate); Andergin(nitrate); Conofite(nitrate); Daktarin (TN); Femizol (TN); Femizol-M; Florid(nitrate); Lotrimin AF(nitrate); Micantin (nitrate); Micatin (TN); Miconazex (TN); Miconazol [INN-Spanish]; Miconazole-7; Miconazolum [INN-Latin]; Monista (nitrate); Monistat (TN); Monistat 3 Dual-Pak; Monistat 7 Dual-Pak; Monistat Dual-PAK; Monistat iv (TN); Monistat-Derm; Novo-Miconazole Vaginal Ovules; Epi-Monistat(nitrate); Gyno-Daktar(nitrate); Monistat-Derm (TN); R-14,889; Miconazole (JP15/USP/INN); Miconazole [USAN:BAN:INN:JAN]; Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)-(9CI); Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-(9CI); (+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole; 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole; 1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole; 1-[2,4-Dichloro-beta-([2,4-dichloro-benzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole; 1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole; 1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
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| Activity |
Ki = 55500 nM
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[4] | |||
| Compound Name |
Tamoxifen
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Approved | Compound Info | ||
| Synonyms |
tamoxifen; 10540-29-1; trans-Tamoxifen; Crisafeno; Soltamox; Tamoxifene; Diemon; Tamoxifenum; Tamoxifeno; Tamizam; Istubol; Tamoxen; Citofen; Oncomox; Valodex; Retaxim; Tamoxifene [INN-French]; Tamoxifenum [INN-Latin]; Tamoxifeno [INN-Spanish]; Tamoxifen (Z); Tamoxifen and its salts; Tamoxifen [INN:BAN]; ICI-46474; ICI 47699; TRANS FORM OF TAMOXIFEN; CCRIS 3275; UNII-094ZI81Y45; HSDB 6782; CHEMBL83; EINECS 234-118-0; 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene; Citofen; Nourytam; Novaldex; Tamone; Tamoxifeno;Tamoxifenum; Tomaxithen; Gen-Tamoxifen; Istubal (TN); Nolvadex (TN); Nolvadex-D; Novo-Tamoxifen; Pms-Tamoxifen; Tamoplex (TN); Tamoxifen (INN); Tamoxifen (TN); Trans-Tamoxifen; Valodex (TN); TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1)); Trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene; (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine; (Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine; (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC); (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE; (Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; 1-p-beta-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene; 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene; 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine; 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine; Tamoxifen (Hormonal therapy); [3H]tamoxifen
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| Activity |
EC50 = 56500 nM
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[5] | |||
| Compound Name |
Simvastatin
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Approved | Compound Info | ||
| Synonyms |
Cholestat; Coledis; Colemin; Corolin; Denan; Labistatin; Lipex; Lipovas; Lodales; Medipo; Nivelipol; Pantok; Rendapid; Simovil; Simvastatina; Simvastatine; Simvastatinum; Sinvacor; Sivastin; Synvinolin; Vasotenal; Zocor; Zocord; Simvast CR; Simvastatina [Spanish]; Simvastatine [French]; Simvastatinum [Latin]; MK 0733; MK 733; MK733; TNP00259; DRG-0320; KS-1113; L 644128-000U; MK-0733; MK-733; Simcard (TN); Simlup (TN); Simvacor (TN); Simvastatin & Primycin; Simvastatin, Compactin; Zocor (TN); Simvastatin [USAN:INN:BAN]; Simvastatin (JAN/USP/INN); Zocor, Simlup, Simcard, Simvacor, Simvoget, Zorced, Simvastatin; [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate; Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester; Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester; Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,*aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester; (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate; Butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1-naphthalenyl ester, [1S-[1 alpha,3 alpha,7 beta,8 beta(2S*,4S*),-8a beta; 2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester; 2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
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| Activity |
IC50 = 56800 nM
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[3] | |||
| Compound Name |
Felodipine
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Approved | Compound Info | ||
| Synonyms |
Agon; Felobeta; Felocor; Feloday; Felodipina; Felodipinum; Felodur; Felogamma; Felogard; Fensel; Flodil; Hydac; Lexxel; Logimax; Modip; Munobal; Penedil; Perfudal; Plandil; Plendil; Preslow; Prevex; Renedil; Splendil; AGON SR; AbZ Brand of Felodipine; Aliud Brand of Felodipine; Alphapharm Brand of Felodipine; Alpharma Brand of Felodipine; Astra Brand of Felodipine; AstraZeneca Brand of Felodipine; Aventis Brand of Felodipine; Azupharma Brand of Felodipine; BC Brand of Felodipine; Betapharm Brand of Felodipine; Ct Arzneimittel Brand of Felodipine; Felo Biochemie; Felo Puren; Felodipin AL; Felodipin AZU; Felodipin AbZ; Felodipin Heumann; Felodipin Stada; Felodipin dura; Felodipin ratiopharm; Felodipin von ct; FelodurER; Heumann Brand of Felodipine; Hexal Brand of Felodipine; Hoechst Brand of Felodipine; Merck dura Brand of Felodipine; Munobal Retard; Pharmaceutica Astra Brand of Felodipine; Pharmacia Spain Brandof Felodipine; Plendil Depottab; Plendil ER; Plendil Retard; Promed Brand of Felodipine; Ratiopharm Brand of Felodipine; Stadapharm Brand of Felodipine; TheraPharm Brand of Felodipine; Worwag Brand of Felodipine; F 9677; Felodipin 1A Pharma; H 154 82; H 15482; CGH-869; Ct-Arzneimittel Brand of Felodipine; Dl-Felodipine; Felo-Puren; Felodipin-ratiopharm; Felodipina [INN-Spanish]; Felodipinum [INN-Latin]; H 154-82; H 154/82; Heumann, Felodipin; Plendil (TN); AE-641/11429675; Felodipine [USAN:BAN:INN]; Felodipine [USAN:INN:BAN]; H-154/82; Felodipine (JAN/USP/INN); Plendil, Renedil, Feloday, Felodipine; Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; (+-)-Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate; (+/-)-ethylmethyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate; 1A Brand of Felodipine; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-, ethyl methylester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-,ethyl methyl ester; 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester; 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate; 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester; 4-(2,3-dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester; 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester; 5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
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| Activity |
IC50 ~ 60000 nM
|
[3] | |||
| Compound Name |
Diltiazem
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Approved | Compound Info | ||
| Synonyms |
Acalix; Adizem; Aldizem; Anoheal; Cardil; Cardizem; Citizem; Dilacor; Dilcontin; Dilren; Diltia; Diltiazemum; Dilticard; Diltzac; Dilzen; Endrydil; Viazem; Cardizen LA; Incoril AP; Tiazac Tildiem; Tiazac XC; Adizem (TN); Altiazem (TN); Angiozem (TN); Angizem (TN); Angizem CD (TN); Apo-Diltiaz; Cardizem (Hydrochloride); Cardizem (TN); Cartia XT (TN); Dilacor-XR; Dilatam (TN); Dilatem (TN); Dilcardia (TN); Dilcontin SR (TN); Dilt-cd; Dilta-Hexal; Diltelan (TN); Diltiazem (INN); Diltiazem [INN:BAN]; Diltiazemum [INN-Latin]; Diltime (TN); Dilzem (TN); Dyalec (TN); Filazem (TN); Herben (TN); Nu-Diltiaz; Progor (TN); RG 83606 (Hydrochloride); Surazem (TN); Tiamate (TN); Tiazac (TN); Tiazac XC (TN); Tildiem (TN); Vasmulax (TN); Viazem (TN); Zandil (TN); Zemtrial (TN); D-cis-Diltiazem; MK-793 (Malate); [(2S,3S)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate; Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester; (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester; (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate; (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate; (2S,3S)-5-[2-(dimethylamino)ethyl]-2-[4-(methyloxy)phenyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate; (2S-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
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| Activity |
IC50 = 61659.5 nM
|
[6] | |||
| Compound Name |
Lovastatin
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Approved | Compound Info | ||
| Synonyms |
lovastatin; 75330-75-5; mevinolin; Mevacor; Lovalip; Monacolin K; Lovalord; Mevinacor; Altoprev; Nergadan; Artein; Altocor; 6alpha-Methylcompactin; MK-803; Hipovastin; Lovastatine; Lovasterol; Paschol; Lipivas; Closterol; Teroltrat; Tecnolip; Rovacor; Cholestra; Rodatin; Lozutin; Lipofren; Lestatin; Hipolip; Colevix; Sivlor; Taucor; Lipdip; Belvas; Mevlor; Lovastatine [French]; Lovastatinum [Latin]; Lovastatina [Spanish]; 6-alpha-Methylcompactin; Lovastatinum; Lovastatina; Lovastin; MSD 803; MK 803; 6 alpha-Methylcompactin; UNII-9LHU78OQFD; Altocor; Liposcler; Mevinolin; Rextat; Sivlor;Taucor; Monakolin K; MK803; Advicor (TN); Altocor (TN); Altoprev (TN); L-154803; Lovastatin & Primycin; ML-530B; Mevacor (TN); Mevinolin from Aspergillus sp; Statosan (TN); Lovastatin (USP/INN); Lovastatin [USAN:BAN:INN]; Lovastatin, (1 alpha(S*))-Isomer; Lovastatin, 1 alpha-Isomer (without R*/S* notation); 2beta,6alpha-Dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone; 6 Methylcompactin; 6-Methylcompactin; Aspirin/lisinopril/ lovastatin fixed-dose combination
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| Activity |
IC50 = 67000 nM
|
[7] | |||
| Compound Name |
Atazanavir
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Approved | Compound Info | ||
| Synonyms |
198904-31-3; Latazanavir; Zrivada; Reyataz; BMS-232632; BMS 232632; Atazanavir [INN:BAN]; CGP 73547; Atazanavir Base; UNII-QZU4H47A3S; CGP-73547; HSDB 7339; Reyataz (TN); ATV; QZU4H47A3S; CHEMBL1163; CHEBI:37924; (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5,6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER; NCGC00182552-01; AK174307; DSSTox_CID_28617; DSSTox_RID_82887; DSSTox_GSID_48691; DR7; atazanavirum; ATZ; Atazanavirum; Atazanavir (INN); Reyataz, BMS-232632, Atazanavir; Reyataz(TM) (*1:1 sulfate*); Dimethyl (3S,8S,9S,12S)-9-benzyl-3,12-di-tert-butyl-8-hydroxy-4,11-dioxo-6-[4-(2-pyridyl)benzyl]-2,5,6,10,13-pentaazatetradecanedioate; METHYL [(1S,4S,5S,10S)-4-BENZYL-1,10-DI-TERT-BUTYL-5-HYDROXY-2,9,12-TRIOXO-7-(4-PYRIDIN-2-YLBENZYL)-13-OXA-3,7,8,11-TETRAAZATETRADEC-1-YL]CARBAMATE; Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate; (2S)-N-(3-{[(2S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoylamino][(4-(2-pyridyl)phenyl)methyl]amino}(1S,2S)-2-hydroxy-1-benzylpropyl)-2-(methoxycarbonylamino)-3,3-dimethylbutanamide
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| Activity |
IC50 = 67800 nM
|
[8] | |||
| Compound Name |
Quinine
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Approved | Compound Info | ||
| Synonyms |
Aflukin; Chinin; Chinine; Chininum; Conchinin; Conquinine; Quindan; Quinidex; Quinidine; Quinimax; Quinina; Quinineanhydrous; Quinora; Quniacridine; Chinin [German]; Kinder Quinina; QUININE MONO HCL; Quinine Dab; Quinine [BAN]; Quinine anhydrous; Quinine bisulfate; Quinine sulfate; Quinine sulphate; Quinoline alkaloid; LT00645788;Q0028; SB01652; Beta-Quinine; Cin-Quin; Coco-Quinine; IBS-L0034250; Kinder Quinina (TN); Legatrin (TN); Quinine (BAN); Quinine, Anhydrous; Quinine, polymers; Quinine, tannate; Biquinate (*Bisulfate heptathydrate*); Dentojel (*Bisulfate heptathydrate*); Quinamm (*2:1 Sulfate salt*), dihydrate; Quine (*2:1 Sulfate salt*, dihydrate); Quinsan (*2:1 Sulfate salt*), dihydrate; Alpha-(6-Methoxy-4-quinoyl)-5-vinyl-2-quinclidinemethanol; Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)-, sulfate; (+)-Quinidine; (-)-Quinine; (1R)-(6-Methoxyquinolin-4-yl)((1S,4S,5R)-5-vinylquinuclidin-2-yl)methanol; (3A,8A,9r)-6'-methoxycinchonan-9-ol; (5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol; (8-alpha,9R)-6'-Methoxycinchonan-9-ol; (8.alpha.,9R)-6'-Methoxycinchonan-9-ol; (8S,9R)-6'-Methoxycinchonan-9-ol; (8S,9R)-Quinine; (9R)-6'-methoxy-8alpha-cinchonan-9-ol; (R)-(-)-Quinine, 6-methoxycinchonidine; (R)-(-)-quinine; (R)-(6-Methoxy-quinolin-4-yl)-((2S,5S)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol; (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol; (R)-[(2S,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (R)-[(2S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (S)-(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol; (S)-[(2R,4R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; 6'-Methoxycinchonan-9-ol; 6'-Methoxycinchonidine; 6'-Methoxycinchonine; 6-Methoxycinchonine
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| Activity |
IC50 = 74400 nM
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[3] | |||
| Compound Name |
Progesterone
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Approved | Compound Info | ||
| Synonyms |
progesterone; 57-83-0; Agolutin; Pregn-4-ene-3,20-dione; Luteohormone; Crinone; 4-Pregnene-3,20-dione; Utrogestan; Syngesterone; Progestin; Luteol; Corpus luteum hormone; Progesterol; Progesteronum; Pregnenedione; Glanducorpin; Prometrium; Corlutin; Cyclogest; Progestron; Gestormone; Progestone; Gestone; Progestasert; Progestronol; Methylpregnone; Hormoflaveine; Syngestrets; Proluton; Progekan; Nalutron; Lutoform; Gynlutin; Gesterol; Fologenon; Corporin; Corlutina; Syntolutan; Prolidon; Membrettes; Lutocyclin; Luteodyn; Lucorteum; Corluvite; LPCN-1107; Progesterone (oral, preterm labor); Progesterone (oral, preterm labor), Lipocine
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| Activity |
IC50 = 88100 nM
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[3] | |||
| Compound Name |
Omeprazole
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Approved | Compound Info | ||
| Synonyms |
Losec (TN)
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| Activity |
IC50 = 89000 nM
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[9] | |||
| Compound Name |
Dolutegravir
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Approved | Compound Info | ||
| Synonyms |
1051375-16-6; GSK1349572; Tivicay; S/GSK1349572; Dolutegravir (GSK1349572); S-349572; GSK-1349572; GSK 1349572; UNII-DKO1W9H7M1; (4r,12as)-N-(2,4-Difluorobenzyl)-7-Hydroxy-4-Methyl-6,8-Dioxo-3,4,6,8,12,12a-Hexahydro-2h-Pyrido[1',2':4,5]pyrazino[2,1-B][1,3]oxazine-9-Carboxamide; CHEBI:76010; DKO1W9H7M1; Tivicay (TN); (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Dolutegravir Sodium (
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| Activity |
IC50 ~ 90000 nM
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[10] | |||
| Compound Name |
Doxorubicin
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Approved | Compound Info | ||
| Synonyms |
doxorubicin; 23214-92-8; Doxil; Doxorubicine; Adriablastin; Doxorubicinum; 14-Hydroxydaunomycin; 14-Hydroxydaunorubicine; Doxorubicina; Adriamycin semiquinone; Doxorubicinum [INN-Latin]; Doxorubicine [INN-French]; Doxorubicina [INN-Spanish]; Myocet; FI 106; Doxorubicin [USAN:INN:BAN]; CCRIS 739; NDC 38242-874; HSDB 3070; UNII-80168379AG; NCI-C01514; EINECS 245-495-6; CHEMBL53463; CHEBI:28748; 5,12-Naphthacenedione,; ADM; ADR; ThermoDox; Aerosolized Doxorubicin; Doxorubicin citrate; RDF Rubex; Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74; DM2; JT9100000; Adiblastine (hydrochloride salt); Adr iablatina (hydrochloride salt); Adriablastine (hydrochloride salt); Adriablatina (hydrochloride salt); Adriacin (hydrochloride salt); Adriamycin PFS (TN); Adriamycin PFS (hydrochloride salt); Adriamycin RDF (TN); Adriamycin RDF (hydrochloride salt); Adriblastina (TN); Adriblastina (hydrochloride salt); Adriblatina (hydrochloride salt); Caelyx (TN); Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120; DOX-SL; Doxorubicin hydrochloride (hydrochloride salt); Doxorubicin-hLL1; Doxorubicin-hLL1 conjugate; Farmablastina (hydrochloride salt); Hydroxydaunomycin hydrochlor ide (hydrochloride salt); Hydroxydaunomycin hydrochloride (hydrochloride salt); Hydroxydaunorubicin hydrochloride (hydrochloride salt); Myocet (TN); Rubex (TN); Rubex (hydrochloride salt); TLC D-99; Doxorubicin (USAN/INN); Doxorubicin-P4/D10; Doxorubicin-P4/D10 conjugate; Cantide + adriamycin
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| Activity |
IC50 = 96910 nM
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[11] | |||
| Compound Name |
Ergotamine
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Approved | Compound Info | ||
| Synonyms |
Avetol; Cornutamin; Cornutamine; ETIN; Ergam; Ergate; Ergomar; Ergonsvine; Ergostat; Ergotamin; Ergotartrate; Exmigra; Femergin;Gynergen; Lingraine; Lingran; Migretamine; Rigetamin; Secagyn; Secupan; Temigran; Wigrettes; Ergotamine bitartrate; Ergotamine hemitartrate; Ergotamine tartrate; Gotamine tartrate; Medihaler ergotamine; Ergomar (TN); Ergotamina [INN-Spanish]; Ergotamine (INN); Ergotamine [INN:BAN]; Ergotamine tartrate (VAN); Ergotaminum [INN-Latin]; Ergoton-A; Neo-ergotin; Ergotamine, tartrate (2:1); Ergotamine tartrate, Avetol, Cornutamin, Ergam, Ergotartrate; ERGOTAMINE (SEE ALSO: ERGOTAMINE TARTRATE (CAS 379-79-3)); Ergotamine, tartrate (2:1) (salt) (8CI); Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'-alpha)-(9CI); Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5alpha)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1); Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) (salt); (5'A)-5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxoergotaman 2,3-dihydroxybutanedioate(2:1); 12'-Hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione
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| Activity |
Ki = 98900 nM
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[4] | |||
| Compound Name |
Darunavir
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Approved | Compound Info | ||
| Synonyms |
206361-99-1; TMC114; Prezista; TMC-114; UIC-94017; Darunavirum; TMC 114; Darunavirum [INN-Latin]; UNII-YO603Y8113; AIDS073035; CHEMBL1323; (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE; CHEBI:367163; Darunavir-d9; YO603Y8113; (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate; NCGC00168773-01; (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl; Darunavirum; Darunavir [USAN]; UIC 94017; Prezista(TM); UIC-96017; Darunavir (USAN/INN); Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester; {(1S,2R)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl) ester; [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid (3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl) ester; N-((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6-dioxabicyclo(330)oct-2-yloxy)carboxamide; [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate; (3-((4-aminobenzenesulfonyl)isobutylamino)-1-benzyl-2-hydroxypropyl)carbamic acid hexahydrofuro(2,3-b)furan-3-yl ester; (3R,3aS,6aR)-Hexahydrofuro(2,3-b)furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido)propyl)carbamate; (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N(1)-isobutylsulfanilamido)propyl)carbamate; (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate; (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate; (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
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| Activity |
IC50 ~ 100000 nM
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[8] | |||
| Compound Name |
Amprenavir
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Approved | Compound Info | ||
| Synonyms |
AMV; Agenerase; Amprenavir[usan]; Prozei; Vertex; Amprenavir [USAN]; VX 478; VX478; Vertex VX478; Agenerase (TM); Agenerase (TN); DRG-0258; GNA & Amprenavir; HHA & Amprenavir; KVX-478; VX-478; Amprenavir (JAN/USAN/INN); Tetrahydro-3-furyl N-(3-(4-amino-N-isobutylbenzenesulfonamido)-1-benzyl-2-hydroxypropyl)carbamate; {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER; [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate; Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3S)-tetrahydro-3-furanyl ester; Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3S)-tetrahydro-3-furanyl ester & Galanthus nivalis agglutinin (GNA); Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3S)-tetrahydro-3-furanyl ester & Hippeastrum hybrid agglutinin(HHA); (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate; (3S)-Tetrahydro-3-furyl ((alphaS)-alpha-((1R-1-hydroxy-2-(N(sup 1)-isobutylsulfanilamido)ethyl)phenethyl)carbamate; (3S)-tetrahydro-3-furyl N-[(1S,2R)-3-(4-amino-N-isobutylbenzenesulfonamido)-1-benzyl-2-hydroxy-propyl]carbamate; (3S-(3R*(1R*,2S*)))-(3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl) tetrahydro-3-furanyl carbamate; 4-Amino-N-((2 syn,3S)-2-hydroxy-4-phenyl-3-((S)-tetrahydrofuran-3-yloxycarbonylamino)-butyl)-N-isobutyl-benzenesulfonamide
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
Ergonovine
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Approved | Compound Info | ||
| Synonyms |
Basergin; Ergobasin; Ergobasine; Ergoklinine; Ergometrin; Ergometrina; Ergometrine; Ergometrinum; Ergostetrine; Ergotocine; Ergotrate; Margonovine; Neofemergen; Secacornin; Secometrin; Ergotrate Maleate; Lysergic acid propanolamide; Ergometrina [INN-Spanish]; Ergometrine (INN); Ergometrine [INN:BAN]; Ergometrinum[INN-Latin]; D-Lysergic acid 1-hydroxymethylethylamide; D-Lysergic acid-L-propanolamide; L-Lysergic-L(beta-hydroxyisopropylamide); N-(1-(Hydroxymethyl)ethyl)-D-lysergamide; N-(alpha-(Hydroxymethyl)ethyl)-D-lysergamide; N-(2-Hydroxy-1-methylethyl)-D(+)-lysergamide; N-[(2S)-1-hydroxypropan-2-yl]-6-methyl-9,10-didehydroergoline-8beta-carboxamide; [8beta(S)]-9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8-carboxamide; 9,10-Didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8beta(S)-carboxamide; 9,10-Didehydro-N-(alpha-(hydroxymethyl)ethyl)-6-methylergoline-8-beta-carboxamide
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||||
| Activity |
Ki ~ 100000 nM
|
[4] | |||
| Compound Name |
Indinavir
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|
Approved | Compound Info | ||
| Synonyms |
Crixivan; IDV; Indinavir [USAN]; L 735524; Crixivan (TM); Crixivan (TN); L-735 524; L-735524; MK-639; Propolis+Indinavir; RS-253; L-735,524; Indinavir, Sulfate (1:1); Indinavir (*1:1 Sulfate salt*); N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE; Propolis & 4-Hydroxy-N-(2-hydroxy-2,3-dihydro-1H-1-indanyl)-N'-(1,1-dimethylethyl)-2-phenylmethyl-5-[4-(3-pyridylmethyl)-1-piperzinyl]hexanediamide; (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-Pentonamide; (2S)-1-[(2S,4S)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide
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||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
Saquinavir
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|
Approved | Compound Info | ||
| Synonyms |
Fortovase; Invirase; ROC; SQV; Saguinavir; Ro 318959; Fortovase (TN); Fortovase(TM); Invirase (TN); Ro 31-8959; Invirase(TM)(monomesylate); Ro-31-8959; Saquinavir (JAN/USP/INN); QNC-ASN-HPH-DIQ-NTB; CIS-N-TERT-BUTYL-DECAHYDRO-2-[2(R)-HYDROXY-4-PHENYL-3(S)-[[N-2-QUINOLYLCARBONYL-L-ASPARAGINYL]AMINO]BUTYL]-(4AS)-ISOQUINOLINE-3(S)-CARBOXAMIDE; (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide; (2s)-N-[(2s,3r)-4-[(2s,3s,4as,8as)-3-(Tert-Butylcarbamoyl)-3,4,4a,5,6,7,8,8a-Octahydro-1h-Isoquinolin-2-Yl]-3-Hydroxy-1-Phenyl-Butan-2-Yl]-2-(Quinolin-2-Ylcarbonylamino)butanediamide
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||||
| Activity |
IC50 = 100000 nM
|
[8] | |||
| Compound Name |
Daunorubicin
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Approved | Compound Info | ||
| Synonyms |
daunorubicin; Daunomycin; 20830-81-3; Rubidomycin; Cerubidine; Daunorubicine; Acetyladriamycin; Leukaemomycin C; Daunorubicinum; Daunarubicinum; Daunorrubicina; Daunamycin; Cerubidin; DaunoXome; Rubomycin C; (+)-Daunomycin; Daunoblastin; Anthracyline; Rubomycin; Daunorubicinum [INN-Latin]; RP 13057; Daunorubicin [INN:BAN]; RCRA waste no U059; FI6339; NSC-82151; DAUNORUBICIN HCL; DaunoXome (TN); UNII-ZS7284E0ZP; CCRIS 914; ZS7284E0ZP; CHEBI:41977; HSDB 5095; C27H29NO10; NCI-C04693; EINECS 244-069-7; Ondena; NSC 83142; Acetyladriamycin; Daunoblastine; Antibiotics from Streptomyces coeruleorubidus; DM1; FI 6339; Dauno-Rubidomycine; Daunorubicin (INN); Daunorubicin (liposomal); Daunorubicin, Hydrochloride; VS-103; (1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside; (1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside; (7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; (8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione; (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; Anthracycline
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||||
| Activity |
Ki = 111000 nM
|
[12] | |||
| Compound Name |
Alfentanil
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|
Approved | Compound Info | ||
| Synonyms |
Alfenta; Alfentanilum; Alfentanyl; Alfenta (TN); Alfentanil (INN); Alfentanil [INN:BAN]; Alfentanilum [INN-Latin]; Rapifen (TN); N-[1-[2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl]-4-(methoxymethyl)-4-piperidyl]propionanilide; N-[1-[2-(4-ethyl-5-oxotetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl]-N-phenylpropanamide; N-(1-(2-(4-Ethyl-4,5-dihydro-5-oxotetrazolyl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilid; N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilide; N-(1-(2-(4-Ethyl-4,5-dihydro-5-oxotetrazolyl)ethyl)-4-(methoxymethyl)-4-piperidyl)-N-phenylpropionamid; N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide; N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl]-4-[(methyloxy)methyl]piperidin-4-yl}-N-phenylpropanamide
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||||
| Activity |
IC50 = 112000 nM
|
[13] | |||
| Compound Name |
Nifedipine
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Approved | Compound Info | ||
| Synonyms |
Adalat; Adalate; Adapine; Adapress; Afeditab; Alat; Aldipin; Alfadal; Alonix; Angipec; Anifed; Anpine; Aprical; Bonacid; Calcibloc; Calcigard; Calcilat; Camont; Cardifen; Cardilat; Cardionorm; Chronadalate; Citilat; Coracten; Coral; Cordafen; Cordaflex; Cordalat; Cordicant; Cordilan; Cordipin; Cordipine; Corinfar; Corotrend; Corynphar; Depin; Dignokonstant; Dilafed; Dipinkor; Duranifin; Ecodipi; Ecodipin; Emaberin; Fedcor; Fenamon; Fenigidin; Fenihidin; Fenihidine; Glopir; Hadipin; Hexadilat; Infedipin; Introcar; Kordafen; Korinfar; Macorel; Megalat; Myogard; Nedipin; Nicardia; Nifangin; Nifar; Nifdemin; Nifebene; Nifecard; Nifecor; Nifedepat; Nifediac; Nifedical; Nifedicor; Nifedin; Nifedine; Nifedipino; Nifedipinum; Nifedipres; Nifelan; Nifelat; Nifelate; Nificard; Nifidine; Nifipen; Niphedipine; Orix; Oxcord; Pidilat; Procardia; Sepamit; Tibricol; Vascard; Zenusin; AWD Pharma Brand of Nifedipine; Adalat CC; Adalat CR; Adalat Crono; Adalat FT; Adalat GITS; Adalat LA; Adalat LP; Adalat Oros; Adalat PA; Adalat Retard; Adalat XL; Adalate LP; Adcock Ingram Brand of Nifedipine; Adipine XL; Afeditab CR; Alonix S; Aprical long; Bayer Brand of Nifedipine; Chronadalate LP; Coracten XL; Ecodipin E; Fedcor Retard; Fenamon SR; Fortipine LA; KRKA Brand of Nifedipine; Nifedical XL; Nifedipine Bayer Brand; Nifedipine GTIS; Nifedipine KRKA Brand; Nifedipine Monohydrochloride; Nifedipine Orion Brand; Nifedipine Pfizer Brand; Nifedipine Retard; Nifedirex LP; Nifelat Q; Nifensar XL; Orion Brand of Nifedipine; Pfizer Brand of Nifedipine; Procardia XL; Slofedipine XL; Tensipine MR; Adalat 10; Adalat 20; Adalat 5; Adalat GITS 30; Bay1040; N 7634; N1fedilat; Adalat (TN); Afeditab CR (TN); Alpha-Nifedipine Retard;Apo-Nifed; Bay-1040; KB-1712P; Monohydrochloride, Nifedipine; Nifedical (TN); Nifedipine-GTIS; Nifedipino [INN-Spanish]; Nifedipinum [INN-Latin]; Procardia (TN); Bay-a-1040; Nifedipine (JP15/USP/INN); Nifedipine [USAN:BAN:INN:JAN]
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||||
| Activity |
IC50 = 113000 nM
|
[14] | |||
| Compound Name |
Dihydroergotamine
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Approved | Compound Info | ||
| Synonyms |
Migranal (TN)
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|
||||
| Activity |
Ki = 119940 nM
|
[4] | |||
| Compound Name |
Metoprolol
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|
Approved | Compound Info | ||
| Synonyms |
Beatrolol; BelocDuriles; Betaloc; BetalocAstra; Betalok; Dutoprol; LOPRESSIDONE; Lopresor; Lopresoretic; Lopressor; Meijoprolol; Metohexal; Metoprololum; Metroprolol; Preblok; Presolol; Seloken; Seroken; Spesicor; Spesikor; Toprol; AstraZeneca Brand of Metaoprolol Tartrate; AstraZeneca Brand of Seloken; Beloc Duriles; Betaloc Astra; Leiras Brand of Metoprolol Succinate or Metoprolol Tartrate; Metoprolol succinate; Novartis Brand of Metprolol Tartrate; Seloken AstraZeneca Brand; CGP 2175; CGP2175; H 93 26; H 9326; Beloc-Duriles; Betaloc (TN); Betaloc-Astra; CGP-2175; Corvitol (TN); Dl-Metoprolol; H 93-26; Lopressor (TN); Metoprololum [INN-Latin]; Metrol (TN); Minax (TN); Neobloc (TN); Selo-Zok; Selokeen (TN); TOPROL-XL; Tartrate, Metoprolol; Metoprolol (USAN/INN); Metoprolol [USAN:INN:BAN]; Toprol-XL (TN); (RS)-Metoprolol; 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol; 1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol; 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol; 1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol; 1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol; 3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol
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||||
| Activity |
Ki = 200000 nM
|
[9] | |||
| Compound Name |
Resveratrol
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|
Phase 3 | Compound Info | ||
| Synonyms |
Resveratrol; Resvida; KUC104385N; R 5010; SRT 501; Cis-resveratrol; PREVENTION 8 (RESVERATROL); RM-1812; SRT-501; Trans-resveratrol; CU-01000001503-3; KSC-10-164; Resveratrol-3-sulfate; Trans-3,4',5-trihydroxystilbene; Trans-3,4′,5-Trihydroxystilbene; Trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene; (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol
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||||
| Activity |
IC50 = 60000 nM
|
[15] | |||
| Compound Name |
PIPERINE
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Phase 1/2 | Compound Info | ||
| Synonyms |
piperine; 94-62-2; 1-Piperoylpiperidine; Piperin; Bioperine; Piperoylpiperidine; (E,E)-1-piperoylpiperidine; N-[(E,E)-Piperoyl]piperidine; Piperidine, 1-piperoyl-, (E,E)-; UNII-U71XL721QK; FEMA No. 2909; CCRIS 5572; Piperine (aliphatic); 1-Piperoylpiperidine, (E,E)-; 7780-20-3; C17H19NO3; EINECS 202-348-0; NSC 21727; 1-[(2E,4E)-5-(1,3-benzodioxol-5-yl)penta-2,4-dienoyl]piperidine; N-(E,E)-piperoyl-piperidine; CHEMBL43185; U71XL721QK; CHEBI:28821; MXXWOMGUGJBKIW-YPCIICBESA-N; NSC21727; piperidine, 1-[(2E,4E)-5-(1,3-benzodioxol-5-yl)
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||||
| Activity |
IC50 = 74100 nM
|
[16] | |||
| Compound Name |
Flavonoid derivative 4
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Patented | Compound Info | ||
| Synonyms |
PMID26394986-Compound-48
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||||
| Activity |
IC50 = 52500 nM
|
[17] | |||
| Compound Name |
Forskolin
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Terminated | Compound Info | ||
| Synonyms |
forskolin; Colforsin; 66575-29-9; Coleonol; colforsina; colforsinum; colforsine; Boforsin; Colforsinum [Latin]; Colforsine [French]; Colforsina [Spanish]; Coleonolk; Colforsin [USAN:INN]; UNII-1F7A44V6OU; 7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxylabd-14-en-11-one; EINECS 266-410-9; HL 362; (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate; NSC 357088; NSC 375489; Forskolin, Coleus forskohlii; CHEMBL52606; 1F7A44V6OU; L 75 1362B
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||||
| Activity |
IC50 = 80200 nM
|
[3] | |||
| Compound Name |
Colchicine
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Phase 3 Trial | Compound Info | ||
| Synonyms |
colchicine; 64-86-8; Colchicin; Colchicina; Colchisol; Condylon; Colcin; Colsaloid; Colchicinum; Colchineos; 7alphaH-Colchicine; Colcrys; (S)-colchicine; Colchicin [German]; spindle poison; Colchicina [Italian]; 7-alpha-H-Colchicine; NSC 757; UNII-SML2Y3J35T; N-Acetyl trimethylcolchicinic acid methylether; CCRIS 691; NSC757; HSDB 3044; EINECS 200-598-5; Colchicine
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||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Dexamethasone
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|
Phase 3 Trial | Compound Info | ||
| Synonyms |
Decadron; Dexamethazone; Maxidex; Prednisolone F; Decaspray; Desametasone; Hexadecadrol; Hexadrol; Dexasone; Oradexon; Dexacort; Deltafluorene; Superprednol; Visumetazone; Mediamethasone; Desamethasone; Dergramin; Mymethasone; Dinormon; Dexapolcort; Dexalona; Desameton; Desadrene; Cortisumman; Aphtasolon; Turbinaire; Dextelan; Dexameth; Decaderm; Millicorten; Gammacorten; Fortecortin; Dexadeltone; Dekacort; Dectancyl; Decasone; Dexason; Mexidex; Dexone; Calonat; Corsone; Auxiron; Fluormethylprednisolone; Azium; Dexa-Cortisyl
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||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Hydrocortisone
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|
Phase 3 Trial | Compound Info | ||
| Synonyms |
Cortisol; Acticort; Cetacort; Hydrasson; Hydrocortisyl; Cobadex; Hycort; Signef; Hytone; Cortef; 17-Hydroxycorticosterone; Optef
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Clarithromycin
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|
Phase 2 Trial | Compound Info | ||
| Synonyms |
Biaxin; 6-O-Methylerythromycin; Klaricid; 6-O-Methylerythromycin a; Clarithromycine; Clathromycin; Abbott-56268; Macladin; Kofron; Klacid; Clarith; Veclam; Clarithromycinum; Naxy; A-56268; Erythromycin, 6-O-methyl-; Biaxin XL; TE-031; Klaciped; Heliclar; Claripen; Claribid; Fromilid; Claridar; Bicrolid; Astromen; Mabicrol; Clambiotic; Claricide; Clacine; Abbotic; Clarem; Clacid; Clacee; Klarin; Klabax; Cyllid; Zeclar; Maclar; Klarid; Crixan; Helas; Mavid; Klax; Biaxin filmtab; Adel; Biaxin HP; Biaxin xl filmtab
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||||
| Activity |
IC50 = 50200 nM
|
[3] | |||
| Compound Name |
5-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL197892; 5-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol; SCHEMBL1741908; ZINC28527773; BDBM50186767; 5-(6-hydroxy-2-naphthyl)benzene-1,3-diol; 5-(6-Hydroxy-naphthalen-2-yl)-benzene-1,3-diol
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||||
| Activity |
IC50 = 53000 nM
|
[15] | |||
| Compound Name |
Cyclosporin A
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Phase 2 Trial | Compound Info | ||
| Synonyms |
cyclosporin A; cyclosporine; Neoral; Cyclosporin; Ciclosporine; Sandimmun; Sang-35
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|
||||
| Activity |
EC50 = 80000 nM
|
[18] | |||
| Compound Name |
4,3'',5''-trimethoxy-[1,1':3',1'']-terphenyl
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206919; BDBM50186761
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|
||||
| Activity |
IC50 = 80000 nM
|
[15] | |||
| Compound Name |
1-(benzyloxy)-2-[2-(3-methoxyphenyl)ethyl]benzene
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL214739; 1-(benzyloxy)-2-[2-(3-methoxyphenyl)ethyl]benzene; BDBM50197201
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|
||||
| Activity |
EC50 = 92800 nM
|
[18] | |||
| Compound Name |
2-{[2-(2-phenylethyl)phenoxy]methyl}pyridine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL216198; 2-((2-phenethylphenoxy)methyl)pyridine; 2-{[2-(2-phenylethyl)phenoxy]methyl}pyridine
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||||
| Activity |
EC50 = 100000 nM
|
[18] | |||
| Compound Name |
Fluoxetine
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|
Phase 3 Trial | Compound Info | ||
| Synonyms |
Fluoxetin; Pulvules; Portal; Eufor; Animex-On; Fluoxetina; Fluoxetina [Spanish]; Fluoxetinum; Fluoxetinum [INN-Latin]; Fluoxetina [INN-Spanish]
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||||
| Activity |
IC50 = 115500 nM
|
[19] | |||
| Compound Name |
Emetine hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
EMETINE; 6',7',10,11-Tetramethoxyemetan; BRN 0100829; CHEBI:4781; CHEMBL50588; Cephaeline methyl ether; Cephaline-O-methyl ether; DSSTox_CID_2980; DSSTox_GSID_22980; DSSTox_RID_76816; EINECS 207-592-1; Emetan, 6',7',10,11-tetramethoxy-; Emetin; Emetine [BAN]; Emetine dihydrochloride hydrate; Emetine hydrochloride; GNF-PF-196; HSDB 2150; Ipecine; Methyl cephaeline; Methylcephaeline; TCMDC-125531; UNII-X8D5EPO80M; X8D5EPO80M
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||||
| Activity |
IC50 = 115600 nM
|
[3] | |||
| Compound Name |
3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL217425; 3-((2-phenethylphenoxy)methyl)pyridine; 3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine
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||||
| Activity |
EC50 = 125000 nM
|
[18] | |||
| Compound Name |
Dpdpe
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL294616; BDBM50001683
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|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Methyl 4-[[4-[2-[7-methoxy-6-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779524; BDBM50344755
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|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
4-[[4-[2-[6-Methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-6-carbonylamino)benzoic acid;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779523
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|
||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1,6-Dihydroxy-2-methylhex-4-enyl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372472
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| Activity |
IC50 = 50000 nM
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[21] | |||
| Compound Name |
Ranitidine Base
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Investigative | Compound Info | ||
| Synonyms |
UNII-884KT10YB7; 884KT10YB7; Achedos; Duractin; Istomar; Quicran; Radinat; Ranisen; Raniter; Ulceranin; Urantac; Verlost; Vizerul; Weichilin; Xanidine; Zantadin; Acidex; Atural; Axoban; Ezopta; Logast; Mauran; Randin; Sampep; Vesyca; Weidos; Zantab; Ranin; Ratic; Ul-Pep; Ranitidinum [INN-Latin]; Ranitidina [INN-Spanish]; HSDB 3925; Major ranitidine; Spectrum_001141; Up and up acod redicer; Topcare jeartburn relief; Prestwick0_000201; Prestwick1_000201; Spectrum2_001425; Spectrum3_000909; Spectrum4_001008; SCHEMBL825; KBioGR_001475; KBioSS_001621; DivK1c_000440; Ranitidine [USAN:INN:BAN]; SPBio_001530; SPBio_002102; CHEMBL1790041; DTXSID8045191; KBio1_000440; KBio2_001621; KBio2_004189; KBio2_006757; KBio3_001858; NINDS_000440; EINECS 266-332-5; BDBM50103506; AKOS030228563; DB00863; MCULE-2682233624; KS-0000111Y; DB-054918; FT-0630765; FT-0653261; EC 266-332-5; Q423037
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
(3S,6S,9R,10R,11S,12S,13E,15E,18S)-18-((2E,4E)-6-(1,2-Oxazinan-2-yl)-6-oxohexa-2,4-dien-2-yl)-3-(3-fluoro-5-hydroxybenzyl)-10,12-dihydroxy-6-isopropyl-11-methyl-9-(3-oxobutyl)-19-oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetraone
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Investigative | Compound Info | ||
| Synonyms |
NVP018; CHEMBL3704747; SCHEMBL12958865; BDBM172717; US9090657, 24
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| Activity |
IC50 ~ 50000 nM
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[22] | |||
| Compound Name |
4-[[4-[2-[7-Methoxy-6-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-6-carbonylamino)benzoic acid;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779521
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| Activity |
IC50 ~ 50000 nM
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[20] | |||
| Compound Name |
Bis[[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl] butanedioate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3220342; BDBM50496869
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| Activity |
IC50 = 50000 nM
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[23] | |||
| Compound Name |
4-Tert-butyl-N-{2-[(4-tert-butylbenzyl)sulfanyl]-1,3-benzothiazol-6-yl}benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL224951; ZINC3664368; BDBM50370875; STK724189; AKOS001733647; MCULE-9622757782; SR-01000517564; SR-01000517564-1; 4-(tert-butyl)-N~1~-(2-{[4-(tert-butyl)benzyl]sulfanyl}-1,3-benzothiazol-6-yl)benzamide
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| Activity |
EC50 ~ 50000 nM
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[24] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-15,30-Diethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372482
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| Activity |
IC50 = 50000 nM
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[21] | |||
| Compound Name |
3-Phenylsulfonylfuroxan-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215574; BDBM50324366
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| Activity |
EC50 = 50000 nM
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[25] | |||
| Compound Name |
Methyl 4-(4-(2-(6-methoxy-7-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenylcarbamoyl)-2-(quinoline-6-carboxamido)benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1777831; BDBM50344752
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| Activity |
IC50 ~ 50000 nM
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[20] | |||
| Compound Name |
Methyl 4-[[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779526; BDBM50344753
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| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
4-[[4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoic acid;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779518
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| Activity |
IC50 ~ 50000 nM
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[20] | |||
| Compound Name |
Methyl (1S,12E,14R,15R,18S)-15-ethyl-12-[(4-methoxyphenyl)methoxycarbonylhydrazinylidene]-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4074751; BDBM50235430
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| Activity |
IC50 = 52300 nM
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[26] | |||
| Compound Name |
4-Phenylsulfonylfuroxan-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215575; SCHEMBL10002283; BDBM50324362
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| Activity |
EC50 = 52600 nM
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[25] | |||
| Compound Name |
Methyl (1S,12E,14R,15R,18S)-15-ethyl-17-methyl-12-(phenylhydrazinylidene)-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3605259; BDBM50235449
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| Activity |
IC50 = 52720 nM
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[26] | |||
| Compound Name |
3-Nitro-4-phenyl-furazan 2-oxide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215507; 3-nitro-4-phenyl-1,2,5-oxadiazole 2-oxide; phenylnitrofuroxan; NSC170737; 3-nitro-2-oxido-4-phenyl-1,2,5-oxadiazol-2-ium; DTXSID40305420; BDBM50324365; STK366154; AKOS005443177; NSC-170737; 3-nitro-4-phenyl-1,2,5-oxadiazol-2-ol; ST51058055
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| Activity |
EC50 = 53000 nM
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[25] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,28-octamethyl-6,9,18-tris(2-methylpropyl)-3,21,24-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372463
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| Activity |
IC50 ~ 54000 nM
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[21] | |||
| Compound Name |
4-Phenylsulfonylfuroxan-3-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215577; SCHEMBL9240268; BDBM50324368; 4-(benzenesulfonyl)-2-oxido-1,2,5-oxadiazol-2-ium-3-carbonitrile
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| Activity |
EC50 = 55400 nM
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[25] | |||
| Compound Name |
Dimethyl-[10-[5-(piperidine-1-carbonyl)thiophen-2-yl]-3-thia-17-azapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-1(21),2(11),4,7,9,12-hexaen-6-ylidene]azanium;hexafluorophosphate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205789
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| Activity |
IC50 = 56000 nM
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[27] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21S,24R,30S,33S)-30-[(1R)-1-Hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,6,10,12,15,19,25,28-nonamethyl-9,18,21,24-tetrakis(2-methylpropyl)-3-propan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372506; BDBM50026909
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| Activity |
IC50 = 56000 nM
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[21] | |||
| Compound Name |
Methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)aminocarbonyl)-2-(5-methylpyrazine-2-carbonylamino)benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL457439; BDBM50293012
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| Activity |
IC50 ~ 57000 nM
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[28] | |||
| Compound Name |
1,1':3',1''-Terbenzene-3,4'',5-triol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL207941; BDBM50186749; ZINC38213443; [1,1'';3'',1'''']-terphenyl-4,3'''',5''''-triol
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| Activity |
IC50 = 58000 nM
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[15] | |||
| Compound Name |
N-Tert-butyl-N'-(3-methoxybenzoyl)-3,5-dimethylbenzohydrazide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2286727; BDBM50178985
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| Activity |
IC50 = 58100 nM
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[29] | |||
| Compound Name |
5,7-Dimethoxy-2-[4-[(4-nitrophenyl)methyl]piperazine-1-carbonyl]chromen-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3763302; BDBM50139440
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| Activity |
IC50 = 58200 nM
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[30] | |||
| Compound Name |
2-[4-[(3,4-Difluorophenyl)methyl]piperazin-1-yl]-5,7-dimethoxychromen-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3764781; BDBM50139444
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| Activity |
IC50 = 58500 nM
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[30] | |||
| Compound Name |
N-(2-Fluoro-4-pyridin-3-ylphenyl)pyridine-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3317930; BDBM50056306
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| Activity |
IC50 = 60100 nM
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[31] | |||
| Compound Name |
Lansoprazole
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Investigative | Compound Info | ||
| Synonyms |
Prevacid; Bamalite; Monolitum; Ogastro; Lansoprazol; Agopton; Limpidex; Lanzor; Opiren; Prevacid SoluTab; Lanzopral; Takepron; Zoton; Lanproton; Lansopep; Lasoprol; Mesactol; Aprazol; Blason; Ketian; Lancid; Lanston; Prezal; Ulpax; AG-1749; Pro Ulco; Lansoprazolum; (R)-Lansoprazole; Compraz; Ilsatec; Prosogan; Suprecid; Dakar; Promp; Zoprol; Prevacid Iv; Lanzol-30; AG 1749; Lansoprazol [INN-Spanish]; Lansoprazolum [INN-Latin]; Lansox; Lanzo; A-65006; Prevacid 24HR; TAK-390MR; MLS000069705; Ogast; MFCD00866873; C16H14F3N3O2S; NCGC00015615-02; SMR000058469; DSSTox_CID_3200; MLS-0003247.0001; Prevacid NapraPAC; DSSTox_RID_76922; DSSTox_GSID_23200; Prevacid I.V.; TAK 390MR; Lansophed; Lansoprazole [USAN:BAN:INN]; Lanzol; Lanzul; PrevOnco; Prevacid (TN); HSDB 7204; SR-01000000169; A 65006; BRN 4333393; Lanfast; Lapraz; ABT-006; Lansoprazole,(S); Lansoprazole [USAN:USP:INN:BAN]; LANSAPRAZOLE; CG-4801; PubChem16834; Spectrum_001580; CPD000058469; Prevacid Delayed Release; Opera_ID_1676; Prestwick0_001072; Prestwick1_001072; Prestwick2_001072; Prestwick3_001072; Spectrum2_000444; Spectrum3_000295; Spectrum4_000856; Spectrum5_001521; Lopac-L-8533; CHEMBL480; L 8533; cid_3883; Lopac0_000709; SCHEMBL22365; BSPBio_001084; BSPBio_001830; KBioGR_001491; KBioSS_002060; MLS000759405; MLS001074170; MLS001424235; BIDD:GT0006; DivK1c_000920; SPECTRUM1503926; SPBio_000488; SPBio_002992; BPBio1_001194; GTPL7208; DTXSID4023200; BDBM47032; CTK8F0500; HMS502N22; KBio1_000920; KBio2_002060; KBio2_004628; KBio2_007196; KBio3_001330; KS-00000VHO; Lansoprazole (JP17/USP/INN); Levolansoprazole;(-)-Lansoprazole; NINDS_000920; HMS1571G06; HMS1922M04; HMS2052F05; HMS2093M07; HMS2098G06; HMS2234B10; HMS3262M19; HMS3264E12; HMS3269D15; HMS3371E21; HMS3394F05; HMS3413J05; HMS3654J17; HMS3677J05; HMS3715G06; Pharmakon1600-01503926; Pharmakon1600-01504282; ACT03358; BCP22331; BCP34129; EBD14854; Tox21_110184; Tox21_301023; Tox21_500709; BBL029072; BDBM50070208; CCG-39952; CL0035; NSC758638; NSC758710; s1354; STK621169; AKOS005554811; Tox21_110184_1; AC-1233; CS-1847; DB00448; KS-1075; Lansoprazole, >=98% (TLC), powder; LP00709; MCULE-8446262134; NC00411; NSC-758638; NSC-758710; SB19127; SDCCGSBI-0050687.P004; IDI1_000920; NCGC00015615-01; NCGC00015615-03; NCGC00015615-04; NCGC00015615-05; NCGC00015615-06; NCGC00015615-07; NCGC00015615-08; NCGC00015615-09; NCGC00015615-10; NCGC00015615-11; NCGC00015615-12; NCGC00015615-14; NCGC00015615-15; NCGC00023826-03; NCGC00023826-04; NCGC00023826-05; NCGC00023826-06; NCGC00023826-07; NCGC00254925-01; NCGC00261394-01; NCGC00381720-13; AK308448; HY-13662; SC-15158; SBI-0050687.P003; AB0005100; AB00052388; EU-0100709; FT-0610894; FT-0670721; FT-0670722; L0233; ST51015040; SW197226-4; D00355; AB00052388-17; AB00052388_18; AB00052388_19; 577L453; A800764; Q254296; J-007154; SR-01000000169-2; SR-01000000169-6; SR-01000000169-9; BRD-A49172652-001-05-7; BRD-A49172652-001-13-1; F2173-0222
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| Activity |
IC50 = 62800 nM
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[32] | |||
| Compound Name |
6-Methoxyflavanone
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Investigative | Compound Info | ||
| Synonyms |
6-methoxy-2-phenylchroman-4-one; NSC50184; 6-methoxy-2-phenyl-2,3-dihydrochromen-4-one; NSC-50184; MLS002667344; CHEMBL476292; 4H-1-Benzopyran-4-one, 2,3-dihydro-6-methoxy-2-phenyl-; 6-Methoxy-2-phenyl-chroman-4-one; Flavanone, 6-methoxy-; ACMC-1ADV8; Oprea1_206352; SCHEMBL126192; MEGxp0_001702; ACon1_000173; HMS3079K20; ANW-13793; BDBM50296860; NSC 50184; AKOS015851685; CCG-250432; MCULE-3625538935; NCGC00180811-01; AS-69581; SMR001557111; DB-047764; FT-0634614; M1403; ST50307518; Y2017; 6-Methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one; J-017917; 6-Methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one #; BRD-A89936123-001-01-6; 2,3-Dihydro-6-methoxy-2-phenyl-4H-1-benzopyran-4-one; 6-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one; NCGC00180811-02!6-methoxy-2-phenyl-2,3-dihydrochromen-4-one
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| Activity |
IC50 = 64000 nM
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[33] | |||
| Compound Name |
1-Tert-Butyl-1-(2-chlorobenzoyl)-2-(3-nitrobenzoyl)hydrazine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3814906; BDBM50178992
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| Activity |
IC50 = 64400 nM
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[29] | |||
| Compound Name |
3,4-Dihydroxy-5-methoxy-N-(4-methoxy-2-nitrophenyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945514; BDBM50363106
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| Activity |
IC50 = 65000 nM
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[34] | |||
| Compound Name |
3,4-Dihydroxy-5-methoxy-N-(2-nitro-4-phenylphenyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945517; BDBM50363109
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| Activity |
IC50 = 67000 nM
|
[34] | |||
| Compound Name |
2'-(2-Hydroxy-3-morpholinopropoxy)propiophenone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL143061; BDBM50370878
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| Activity |
EC50 = 67000 nM
|
[24] | |||
| Compound Name |
N-(2-Fluoro-4-pyridin-3-ylphenyl)-3,4-dimethoxybenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3317934; BDBM50056310
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| Activity |
IC50 = 67500 nM
|
[31] | |||
| Compound Name |
2-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206049; BDBM50186766; ZINC13340919; 3',5'-Dimethoxy-trans-stilbene-2-ol; 2-[(E)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenol
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| Activity |
IC50 = 68000 nM
|
[15] | |||
| Compound Name |
Troleandomycin
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Investigative | Compound Info | ||
| Synonyms |
Triacetyloleandomycin; Oleandomycin triacetate; Oleandocetine; Tribiocillina; Oleandomycin triacetyl ester; Cyclamycin; Evramicina; Troleandomicina; Troleandomycine; Triocetin; Troleandomycinum; Triacetyloleandomycinum; Matromicina; Treolmicina; UNII-C4DZ64560D; Oleandomycin, triacetate (ester); C4DZ64560D; Triolan; Viamicina; Wytrion; Aovine; Matromycin T; Treis-Micina; Tao (VAN); Oleandomycin, triacetyl-; Troleandomycine [INN-French]; Troleandomycinum [INN-Latin]; Troleandomicina [INN-Spanish]; Triacetyl ester of oleandomycin; EINECS 220-392-9; WY 651; NSC 108166; NSC-108166; AI3-50166; ACETYLOLEANDOMYCIN; Tao (TN); Prestwick3_000036; Triacetyloleandomycin (JAN); Troleandomycin (USAN/INN); BSPBio_000131; SCHEMBL125071; BPBio1_000145; CHEMBL564085; T.A.O.; HMS2089B10; HMS2095G13; HMS3712G13; Fmoc-(R)-3-Amino-5-hexenoicacid; BDBM50370258; LMPK04000042; Troleandomycin [USAN:USP:INN:BAN]; ZINC169307271; CCG-220036; DB13179; NCGC00179654-01; AB00513798; C12753; D01322; AB00513798-02; Q1087499; BRD-K38310698-001-01-9
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| Activity |
IC50 = 68300 nM
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[3] | |||
| Compound Name |
3,5-Dihydroxy-N-(2-nitro-4-phenylphenyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945512; BDBM50363104
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| Activity |
IC50 = 72000 nM
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[34] | |||
| Compound Name |
3-Methoxy-5-[(2-nitro-4-phenylanilino)methyl]benzene-1,2-diol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945983; BDBM50363075
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| Activity |
IC50 = 72000 nM
|
[34] | |||
| Compound Name |
2-Phenyl-5-methyl-1-[2-hydroxy-3-(propylamino)propyl]-4-(2-thienylcarbonyl)-3H-pyrazole-3-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL338678; BDBM50067118
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| Activity |
EC50 = 72440 nM
|
[35] | |||
| Compound Name |
2-Phenyl-5-methyl-1-[2-hydroxy-3-(tert-butylamino)propyl]-4-(2-thienylcarbonyl)-3H-pyrazole-3-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL338120; BDBM50067121
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| Activity |
EC50 = 72440 nM
|
[35] | |||
| Compound Name |
4-Chloro-2-[(E)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206633; BDBM50186751
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| Activity |
IC50 = 73000 nM
|
[15] | |||
| Compound Name |
Methyl (1S,12E,14R,15R,18S)-15-ethyl-12-hydrazinylidene-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4074765; BDBM50235440
Click to Show/Hide
|
||||
| Activity |
IC50 = 73370 nM
|
[26] | |||
| Compound Name |
N-Tert-Butyl-N'-(2,5-dimethylbenzoyl)-2-chlorobenzhydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2286725; BDBM50179088; J3.553.489J
Click to Show/Hide
|
||||
| Activity |
IC50 = 73600 nM
|
[29] | |||
| Compound Name |
(2S,5S,6R,10R,11S)-5-Benzyl-6-(methoxymethoxy)-4,10,11-trimethyl-2-propan-2-yl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL290433; BDBM50403707
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 75000 nM
|
[2] | |||
| Compound Name |
Chembl4292641
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL10315942; BDBM50464785
Click to Show/Hide
|
||||
| Activity |
EC50 = 76400 nM
|
[36] | |||
| Compound Name |
Methyl (1S,14R,15R,18S)-15-ethyl-17-methyl-12-sulfanylidene-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4083129; BDBM50235432
Click to Show/Hide
|
||||
| Activity |
IC50 = 77920 nM
|
[26] | |||
| Compound Name |
N-Tert-butyl-3,5-dimethyl-N'-(2-methylbenzoyl)benzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3814913; BDBM50178983
Click to Show/Hide
|
||||
| Activity |
IC50 = 79900 nM
|
[29] | |||
| Compound Name |
(5S,6S,10R,11S)-5-Benzyl-10-butyl-6-hydroxy-4,11-dimethyl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288741; BDBM50403693
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
4-Benzoyl-1-(3-tert-butylamino-2-hydroxy-propyl)-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339252; BDBM50067134; 1,2-Dihydro-2-phenyl-5-methyl-1-[2-hydroxy-3-(tert-butylamino)propyl]-4-benzoyl-3H-pyrazole-3-one
Click to Show/Hide
|
||||
| Activity |
EC50 = 81280 nM
|
[35] | |||
| Compound Name |
(2S,3R)-2-Methyl-3-hydroxydecanoic acid (S)-1-(methoxycarbonyl)-2-methylpropyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40173; BDBM50403708
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 83000 nM
|
[2] | |||
| Compound Name |
4-Benzoyl-1-(2-hydroxy-3-isopropylamino-propyl)-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129228; BDBM50067140; 1,2-Dihydro-2-phenyl-5-methyl-1-[2-hydroxy-3-(isopropylamino)propyl]-4-benzoyl-3H-pyrazole-3-one
Click to Show/Hide
|
||||
| Activity |
EC50 = 83180 nM
|
[35] | |||
| Compound Name |
6,7-Dimethoxy-2-[3-(6-methoxy-3,4-dihydronaphthalen-1-yl)propyl]-3,4-dihydro-1H-isoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL260377; SCHEMBL14290593; BDBM50374729
Click to Show/Hide
|
||||
| Activity |
EC50 = 83700 nM
|
[37] | |||
| Compound Name |
Methyl (1S,12S,14R,15S,18S)-15-ethyl-12-hydroxy-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4090917; BDBM50235434
Click to Show/Hide
|
||||
| Activity |
IC50 = 83860 nM
|
[26] | |||
| Compound Name |
5,7-Dimethoxy-2-[4-[2-(4-nitrophenyl)ethyl]piperazine-1-carbonyl]chromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3763433; BDBM50139439
Click to Show/Hide
|
||||
| Activity |
IC50 = 83900 nM
|
[30] | |||
| Compound Name |
Methyl (1S,12E,14R,15R,18S)-15-ethyl-17-methyl-12-(pyrazin-2-ylhydrazinylidene)-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4062327; BDBM50235425
Click to Show/Hide
|
||||
| Activity |
IC50 = 84780 nM
|
[26] | |||
| Compound Name |
Methyl (1S,12E,14R,15S,18S)-15-ethyl-12-hydroxyimino-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4059582; BDBM50235447
Click to Show/Hide
|
||||
| Activity |
IC50 = 85360 nM
|
[26] | |||
| Compound Name |
(3R,4S)-3-(Methoxymethoxy)-4-[methyl(benzyloxycarbonyl)amino]-5-phenylvaleric acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39074; BDBM50403699
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 86000 nM
|
[2] | |||
| Compound Name |
(Z)-3-Hydroxy-1-(4-methoxy-1-benzofuran-5-yl)-3-phenylprop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL900825; CHEMBL458131; ZINC100003085; 5-[(Z)-beta-Hydroxycinnamoyl]-4-methoxybenzofuran
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[38] | |||
| Compound Name |
(3R,4S)-3-Hydroxy-4-[methyl(benzyloxycarbonyl)amino]-5-phenylpentanoic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL37969; BDBM50403701
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 89000 nM
|
[2] | |||
| Compound Name |
Methyl (1S,14R,15R,18S)-15-ethyl-10,17-dimethyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4071619; BDBM50235437
Click to Show/Hide
|
||||
| Activity |
IC50 = 89160 nM
|
[26] | |||
| Compound Name |
(4R,5S)-5-[(2R)-2-[(1R,3As,4E,7aR)-4-[(2Z)-2-[(3S,4S,5R)-3,5-dihydroxy-4-methyl-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]propyl]-4-butyl-3-methylideneoxolan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL384538; SCHEMBL16152901; BDBM50411102
Click to Show/Hide
|
||||
| Activity |
EC50 = 95600 nM
|
[18] | |||
| Compound Name |
Methyl (1S,12S,14R,15R,18S)-12-[(E)-but-2-enoyl]oxy-15-ethyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4062990; BDBM50235435
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
[6-(Dimethylamino)-9-[5-(piperidine-1-carbonyl)thiophen-2-yl]thioxanthen-3-ylidene]-dimethylazanium;hexafluorophosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205786
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
3,4-Diphenyl-1,2,5-oxadiazole 2-oxide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Diphenylfuroxan; NSC52230; CHEMBL1212966; 2-oxido-3,4-diphenyl-1,2,5-oxadiazol-2-ium; 3,4-Diphenyl-1,2lambda(5),5-oxadiazol-2-ol; NSC 52230; CBDivE_005725; SCHEMBL7796584; CTK8J2983; DTXSID80204443; HMS1675N18; NSC54398; ZINC2819563; BDBM50324378; NSC-52230; NSC-54398; STK366156; AKOS000583632; 3,4-diphenyl-1,2,5-oxadiazol-2-ol; EU-0033409; ST50230611; 3,4-diphenyl-1,2,5-oxadiazol-2-ium-2-olate; 2-oxido-3,4-diphenyl-[1,2,5]oxadiazol-2-ium; 3,4-Diphenyl-1,2.lambda.~5~,5-oxadiazol-2-ol; SR-01000389263; SR-01000389263-1
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
4-[[4-(5,7-Dimethoxy-4-oxochromen-2-yl)piperazin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3763752; BDBM50139427
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
2-[[2-[2-(3-Methoxyphenyl)ethyl]phenoxy]methyl]thiophene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3237959; BDBM50009060
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S,5S,6R,11S)-5-Benzyl-6-(methoxymethoxy)-4,11-dimethyl-2-propan-2-yl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40066; BDBM50403698
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
3-Methoxy-4-phenylfuroxan
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215438; 3-Methoxy-4-phenyl-furazan-2-oxide; BDBM50324352; ZINC19878176; 3-methoxy-4-phenyl-1,2,5-oxadiazole 2-oxide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
4-Methyl-3-phenylfuroxan
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215437; Methylphenylfuroxan; SCHEMBL14390587; CTK1J1584; DTXSID00521649; 3-Methyl-4-phenylfurazan 5-oxide; BDBM50324379; 4-methyl-3-phenyl-1,2,5-oxadiazole 2-oxide; 1,2,5-Oxadiazole, 3-methyl-4-phenyl-, 5-oxide; 4-Methyl-2-oxo-3-phenyl-1,2,5lambda~5~-oxadiazole
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
Methyl (1S,12E,14R,15R,18S)-12-(carbamoylhydrazinylidene)-15-ethyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4070955; BDBM50235448
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
(2S,5S,6R,11S)-5-Benzyl-6-hydroxy-4,11-dimethyl-2-propan-2-yl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38750; BDBM50403694
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
5,7-Dimethoxy-2-[4-[[4-(trifluoromethylsulfonyl)phenyl]methyl]piperazin-1-yl]chromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3763805; BDBM50139432
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
[(1S,2R,4S,5R,6R,7S,9R,12R)-4,5,12-Triacetyloxy-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] furan-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL232470; BDBM50221876
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[40] | |||
| Compound Name |
4-[[4-[2-[6-Methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779522
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
4-Nitro-3-phenylfuroxan
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215506; 4-Nitro-3-phenyl-furazan 2-oxide; 3-phenyl-4-nitrofuroxan; 4-nitro-2-oxido-3-phenyl-1,2,5-oxadiazol-2-ium; SCHEMBL9173319; CTK5I4546; 3-Phenyl-4-nitro-furazan-2-oxide; ZINC4955491; BDBM50324354; AKOS000505939; 4-nitro-3-phenyl-1,2,5-oxadiazol-2-ol; ST50215940; 4-Nitro-3-phenyl-1,2,5-oxadiazole 2-oxide; 4-NITRO-3-PHENYL-1,2,5-OXADIAZOL-2-IUM-2-OLATE
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
2-[4-(Benzyloxy)phenyl]-3-(4-ethylphenyl)-2,3-dihydro-4(1H)-quinazolinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL222451; ChemDiv1_010994; Oprea1_513046; Oprea1_677814; HMS618D16; BDBM50370877; STK060281; AKOS001733551; MCULE-8055104084; AG-205/37047245; SR-01000517525; SR-01000517525-1; 2-[4-(benzyloxy)phenyl]-3-(4-ethylphenyl)-2,3-dihydroquinazolin-4(1H)-one
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
Methyl (1S,14R,15S,18S)-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4075029; BDBM50235427
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
5-[[2-[2-(3-Methoxyphenyl)ethyl]phenoxy]methyl]-1,3-benzodioxole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3237958; BDBM50009059
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
3,4,5-Trimethoxy-N-(4-methoxy-2-nitrophenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945301; Cambridge id 5365252; Oprea1_120913; SCHEMBL7917543; ZINC3960317; BDBM50363086; STL482896; AKOS002265481; MCULE-2633362480; ST50183096; n-(2-nitro-4-methoxyphenyl)(3,4,5-trimethoxybenzamide); N-(4-METHOXY-2-NITROPHENYL)-3,4,5-TRIMETHOXYBENZAMIDE; N-(4-methoxy-2-nitrophenyl)(3,4,5-trimethoxyphenyl)carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-30-[(1R)-1-Hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,28-octamethyl-6,9,18-tris(2-methylpropyl)-3,21,24-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372493
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
3,4,5-Trihydroxy-N-(2-nitro-4-phenylphenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945316; BDBM50363101
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
Methyl (2S,3R)-3-hydroxy-2-methyldecanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38854; BDBM50403689; (2S,3R)-2-Methyl-3-hydroxydecanoic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
5,7-Dimethoxy-2-[4-[(2-nitrophenyl)methyl]piperazin-1-yl]chromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3765551; BDBM50139428
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-(3,4-Dihydroxy-5-methoxyphenyl)-2-nitro-4-phenylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945984; BDBM50363076
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
3,4,5-Trimethoxy-N-(2-nitro-4-phenylphenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1944867; SCHEMBL16179942; BDBM50363083
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
[9-[5-(Diethylcarbamoyl)thiophen-2-yl]-6-(dimethylamino)thioxanthen-3-ylidene]-dimethylazanium;hexafluorophosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493431
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,7,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372469; BDBM50026934
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
4-Phenyl-3-furoxancarbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336467; 2-oxido-4-phenyl-1,2,5-oxadiazol-2-ium-3-carbonitrile; Lopac-P-1726; Lopac0_000926; BSPBio_001187; KBioGR_000527; KBioSS_000527; SCHEMBL320190; KBio2_000527; KBio2_003095; KBio2_005663; KBio3_000953; KBio3_000954; 3-Cyano-4-phenylfurazan 2-oxide; Bio2_000424; Bio2_000904; HMS1362K09; HMS1792K09; HMS1990K09; HMS3403K09; ZINC2562608; BDBM50038412; AKOS006273082; 2-Oxy-4-phenyl-furazan-3-carbonitrile; CCG-205007; IDI1_002179; QTL1_000039; NCGC00015800-01; NCGC00015800-02; NCGC00015800-03; NCGC00015800-04; NCGC00015800-05; NCGC00015800-06; NCGC00015800-07; NCGC00094237-01; NCGC00094237-02; NCGC00094237-03; NCGC00094237-04; NCGC00094237-05; NCGC00167918-01; EU-0100926; 3-cyano-4-phenyl-1,2,5-oxadiazole 2-oxide; P 1726; SR-01000076058; 4-phenyl-1,2,5-oxadiazole-3-carbonitrile-2-oxide; SR-01000076058-1; 3-CYANO-4-PHENYL-1,2,5-OXADIAZOL-2-IUM-2-OLATE
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
Methyl (1S,12E,14R,15S,18S)-12-(carbamoylhydrazinylidene)-15-ethyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098041; BDBM50235429
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
4-[4,6-Bis(trifluoromethyl)-1,3,5-triazin-2-yl]-N,N-dimethylaniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL426568; BDBM50370889
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
4-[[4-[2-[7-Methoxy-6-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779520
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
4-Phenyl-3-furoxancarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL500868; SCHEMBL6654477; 2-oxido-4-phenyl-1,2,5-oxadiazol-2-ium-3-carboxamide; BDBM50300754; 3-Carbamoyl-4-phenyl-furazan-2-oxide; NCGC00168363-01; 2-Oxy-4-phenyl-furazan-3-carboxylic acid amide; 3-carbamoyl-4-phenyl-1,2,5-oxadiazole 2-oxide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
Methyl (1S,12E,14R,15S,18S)-15-ethyl-17-methyl-12-(pyrazin-2-ylhydrazinylidene)-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4090331; BDBM50235428
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
Methyl (1S,14R,15R,18S)-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3358048; BDBM50235426
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
5-Methoxy-N-(2-nitro-4-phenylphenyl)-3,4-dioxocyclohexa-1,5-diene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945985; BDBM50363077
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
N-(4-Bromo-2-nitrophenyl)-3,4,5-trihydroxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945315; BDBM50363100
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
Methyl (1S,12S,14R,15R,18S)-15-ethyl-12-hydroxy-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4101113; BDBM50235433
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
Methyl 4-[[4-(5,7-dimethoxy-4-oxochromen-2-yl)piperazin-1-yl]methyl]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3764960; BDBM50139426
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(5S,6S,10R,11S)-5-Benzyl-10-butyl-6-(methoxymethoxy)-4,11-dimethyl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38977; BDBM50403709
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2,4-Dichloro-1-[[2-(2-phenylethyl)phenoxy]methyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3237957; BDBM50009058
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
5-Oxido-4-phenyl-1,2,5-oxadiazol-5-ium-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-amino-3-phenylfuroxane; CHEMBL459673; TimTec1_000175; 4-Phenylfurazanamine 5-oxide; MLS000517224; ZINC55139; HMS1534H21; HMS1757C02; HMS2668M06; 5-Oxy-4-phenyl-furazan-3-ylamine; BDBM50324349; AKOS001062044; NCGC00175393-01; SMR000343339; ST002758; 4-amino-3-phenyl-1,2,5-oxadiazol-2-ol; 4-amino-3-phenyl-1,2,5-oxadiazole 2-oxide; 4-amino-3-phenyl-1,2,5-oxadiazol-2-ium-2-olate; BRD-K09455164-001-01-2; Z56924892
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
3-Methyl-4-phenylsulphonylfuroxan
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320995; furazan,methyl(phenylsulfonyl)-,5-oxide; CTK1C6823; DTXSID20416008; BDBM50324361; ZINC26995372; 4-Benzenesulfonyl-3-methyl-furazan 2-oxide; 3-Methyl-4-(phenylsulfonyl)furazan 2-oxide; 3-methyl-4-(phenylsulfonyl)-1,2,5-oxadiazole 2-oxide; 1,2,5-Oxadiazole, 3-methyl-4-(phenylsulfonyl)-, 2-oxide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
3-Methyl-4-phenylfurazan 2-oxide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL574360; 3-methyl-4-phenylfuroxan; CTK1J1585; DTXSID40481016; BDBM50300758; NCGC00168362-01; 3-methyl-4-phenyl-1,2,5-oxadiazole 2-oxide; 1,2,5-Oxadiazole, 3-methyl-4-phenyl-, 2-oxide; 3-methyl-2-oxido-4-phenyl-1,2,5-oxadiazol-2-ium
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
Methyl (1S,14R,15R,18S)-10-[2-(diethylamino)ethyl]-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4082147; BDBM50235439
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
N-(4-Bromo-2-nitrophenyl)-3,4,5-trimethoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1944869; BDBM50363085
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
Methyl (1S,14R,15R,18S)-15-ethyl-17-methyl-10-(3-methylbenzoyl)-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4094301; BDBM50235443
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
3-Amino-4-phenyl-1,2,5-oxadiazol-2-ium-2-olate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL507873; 3-amino-4-phenylfuroxane; 2-Oxy-4-phenyl-furazan-3-ylamine; Enamine_001115; 3-amino-4-phenylfuroxan; Oprea1_594492; HMS1397C15; ZINC375279; BDBM50324350; STK366155; AKOS000558887; ST002757; 3-amino-4-phenyl-1,2,5-oxadiazol-2-ol; 3-amino-4-phenyl-1,2,5-oxadiazole 2-oxide; Z56788743
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372495; BDBM50026942
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372490
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
3-Phenyl-4-furoxancarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459640; BDBM50324353; 3-Phenyl-4-carbamoyl-furazan-2-oxide; 4-carbamoyl-3-phenyl-1,2,5-oxadiazole 2-oxide; 5-Oxy-4-phenyl-furazan-3-carboxylic acid amide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
(E)-3,5-Di-tert-butyl-3',5'-dimethoxystilbene-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL207989; BDBM50186754; 2,6-di-tert-butyl-4-[(E)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
2-(3,5-Dimethoxy-phenyl)-6-methoxy-naphthalene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL194888; CTK6J9239; BDBM50186753; ZINC21995029; AKOS015966001
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
3,4-Dihydroxy-5-methoxy-N-(4-phenylphenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945978; BDBM50363115
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
Methyl 4-[[4-[2-[7-methoxy-6-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-6-carbonylamino)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779525; BDBM50344754
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Methyl (1S,12S,14R,15S,18S)-12-(adamantane-1-carbonyloxy)-15-ethyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098642; BDBM50235436
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
2-[(4-Amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-2-phenylacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL575236; BDBM50480842
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
3-Phenylfuroxan-4-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215508; 3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide; BDBM50324356
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
1,3-Dimethoxy-5-[4-(4-methoxyphenyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL207826; BDBM50186752; 4,3'''',5''''-trimethoxy-[1,1'';4'',1'''']-terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
5-[(E)-3,5-Dimethoxystyryl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL175736; 3-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol; BDBM50186759; ZINC28114979; 3-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
N-(2-Amino-4-phenylphenyl)-3,4-dihydroxy-5-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945979; BDBM50363116
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
3-Phenyl-4-cyano-furoxan
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL500095; 1,2,5-Oxadiazole-3-carbonitrile, 4-phenyl-, 5-oxide; cyano(phenyl)furoxane; ACMC-20mrjj; 5-oxido-4-phenyl-1,2,5-oxadiazol-5-ium-3-carbonitrile; CTK0C2329; DTXSID90416010; 3-Phenyl-4-cyanofurazan 2-oxide; BDBM50324355; 5-Oxy-4-phenyl-furazan-3-carbonitrile; NCGC00167930-01; 4-cyano-3-phenyl-1,2,5-oxadiazole 2-oxide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
2-alpha-Acetoxy-6-beta,9-beta-difuroyloxy-1-alpha,4-beta-dihydroxy-dihydro-beta-agarofuran
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL393419; BDBM50221875
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[40] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18S,21R,24R,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,25,28-heptamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372478; BDBM50026927
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
2-(4-Amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)sulfanyl-2-phenylacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL582915; BDBM50480849
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
4-Phenylfuroxan-3-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1215509; BDBM50324357; 3-Sulfamoyl-4-phenyl-1,2,5-oxadiazole 2-oxide; 4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-(2-Acetamido-4-phenylphenyl)-3,4-dihydroxy-5-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945981; BDBM50363073
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
(2S,5S,6R,10R,11S)-5-Benzyl-6-hydroxy-4,10,11-trimethyl-2-propan-2-yl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL37203; BDBM50403703
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
N-[1,1'-Biphenyl]-4-yl-3,4,5-trimethoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1944864; ZINC2632372; BDBM50363080; AKOS007990085; MCULE-4433672470; AH-034/04909019; N-([1,1'-Biphenyl]-4-yl)-3,4,5-trimethoxybenzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
4-Methoxy-3-phenylfuroxan
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456685; 4-methoxy-3-phenyl-1,2,5-oxadiazole 2-oxide; ZINC509848; 3-Phenyl-4-methoxy-furazan-2-oxide; BDBM50324351; STL330227; AKOS022114598
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-[4-(3,4-Dihydroxyphenyl)-2-nitrophenyl]-3,4-dihydroxy-5-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945974; BDBM50363111
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
(5S,6S,10R,11S)-5-Benzyl-6-(methoxymethoxy)-4,10,11-trimethyl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38248; BDBM50403687
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
(5S,6S,10R,11S)-5-Benzyl-6-hydroxy-4,10,11-trimethyl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39957; BDBM50403706
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
4-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-2,6-dimethoxy-phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL383273; BDBM50186760; ZINC40763455; 3,3',5,5'-Tetramethoxystilben-4-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
N'-Benzoyl-N-tert-butyl-3,5-dimethylbenzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2228438; Benzoic acid, 3,5-dimethyl-, 2-benzoyl-1-(1,1-dimethylethyl)hydrazide; SCHEMBL8175233; DTXSID80150037; BDBM50178982; N'-t-butyl-N-benzoyl-N'-(3,5-dimethylbenzoyl)hydrazine; 1-Benzoyl-2-tert-butyl-2-(3,5-dimethylbenzoyl)hydrazine
Click to Show/Hide
|
||||
| Activity |
IC50 = 100400 nM
|
[29] | |||
| Compound Name |
N-Tert-butyl-N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylideneamino]oxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL222427; BDBM50370906
Click to Show/Hide
|
||||
| Activity |
EC50 = 102200 nM
|
[24] | |||
| Compound Name |
(3-Methyl-2,3-dihydrobenzofuran-2-yl)(piperidin-1-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL222797; BDBM50207917; AKOS033173626; MCULE-4205321414
Click to Show/Hide
|
||||
| Activity |
EC50 = 103600 nM
|
[24] | |||
| Compound Name |
Ergocornine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000069342; UNII-7W36B25464; SMR000058938; 7W36B25464; 12'-hydroxy-2',5'alpha-bis(1-methylethyl)ergotaman-3',6',18-trione; 12'-hydroxy-3',6',18-trioxo-2',5'alpha-di(propan-2-yl)ergotaman; EINECS 209-272-7; NSC 407316; BRN 0078784; regid856021; Opera_ID_1715; 12'-Hydroxy-2',5'-alpha-bis(1-methylethyl)ergotaman-3',6',18-trione; Biomol-NT_000006; Ergocornine, >95%, solid; SCHEMBL78984; 4-25-00-00963 (Beilstein Handbook Reference); cid_73453; MLS001076288; BPBio1_001133; CHEMBL1385840; BDBM30709; HMS2232G14; ZINC56871297; 12'-Hydroxy-2',5'a-bis(1-methylethyl)-8a-ergotaman-3',6',18-trione; Ergotaman-3',6',18-trione, 12'-hydroxy-2',5'-bis(1-methylethyl)-, (5'-alpha)-; C09162; 15844-EP2275420A1; 15844-EP2280008A2; 15844-EP2298765A1; 15844-EP2316470A2; Q5385809; BRD-K19360254-001-01-3; UNII-2J09Y26C6I component UJYGDMFEEDNVBF-OGGGUQDZSA-N; UNII-J6AIY5049X component UJYGDMFEEDNVBF-OGGGUQDZSA-N
Click to Show/Hide
|
||||
| Activity |
Ki = 105200 nM
|
[4] | |||
| Compound Name |
5-(2,6-Ditert-butylselenopyran-1-ium-4-yl)thiophene-2-carboxylic acid;hexafluorophosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2087763; BDBM50485629
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| Activity |
IC50 = 111000 nM
|
[42] | |||
| Compound Name |
2-Phenyl-5-methyl-1-[2-hydroxy-3-(isopropylamino)propyl]-4-(2-thienylcarbonyl)-3H-pyrazole-3-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129427; BDBM50067135
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| Activity |
EC50 = 123030 nM
|
[35] | |||
| Compound Name |
3'-((2-Hydroxy-3-morpholino)propoxy)acetophenone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149548; BRN 0997334; ACETOPHENONE, 3'-((2-HYDROXY-3-MORPHOLINO)PROPOXY)-; DTXSID00981789; BDBM50370879; 3'-(2-Hydroxy-3-morpholinopropoxy)acetophenone; 1-{3-[2-Hydroxy-3-(morpholin-4-yl)propoxy]phenyl}ethan-1-one
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||||
| Activity |
EC50 = 128000 nM
|
[24] | |||
| Compound Name |
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-12-(4-Aminobutyl)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372473; BDBM50026940
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| Activity |
IC50 = 130000 nM
|
[21] | |||
| Compound Name |
(E)-4-(3-Oxo-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233501; ZINC6639939; BDBM50009288; STK922368; AKOS002322216; ST50769112; VU0610929-1; F3328-0011; 4-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl]benzoic acid; 4-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)prop-1-enyl]benzoic acid
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||||
| Activity |
IC50 = 141253.75 nM
|
[43] | |||
| Compound Name |
2-(1-Azepanyl)-N'-(2-chloro-6-fluorobenzylidene)-2-oxoacetohydrazide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222698; MLS001147638; BDBM50370901; ZINC15986107; SMR000673064; AN-698/40745334
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||||
| Activity |
EC50 = 159300 nM
|
[24] | |||
| Compound Name |
1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol
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Investigative | Compound Info | ||
| Synonyms |
(S)-propranolol; (-)-propranolol; UNII-74MLR03FLC; 74MLR03FLC; (S)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol; CHEMBL452861; (2S)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol; Propranolol, L-; Q63390536; Levopropranolol; s-propranolol; 1-propranolol; (-)-propanolol; propranolol (S-); EINECS 224-095-5; S-(-)-propanolol; s-(-)-propranolol; Tocris-0834; (-)-(S)-Propranolol; Prestwick0_001081; Prestwick1_001081; Prestwick2_001081; Prestwick3_001075; Prestwick3_001081; GTPL63; SCHEMBL3956; Lopac0_001023; BSPBio_001040; BSPBio_001090; BSPBio_001122; KBioGR_000380; KBioSS_000380; SPBio_003021; BPBio1_001200; BPBio1_001236; (S)-(-)-PROPRANOLOL; BCBcMAP01_000208; CTK4I5506; KBio2_000380; KBio2_002948; KBio2_005516; KBio3_000739; KBio3_000740; ZINC56556; DTXSID90873366; Bio2_000360; Bio2_000840; HMS1362D21; HMS1792D21; HMS1990D21; HMS2089B07; 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, (S)-; BDBM50246936; MFCD00066276; PDSP1_000768; PDSP2_000756; CCG-205103; SDCCGSBI-0050996.P004; IDI1_002115; NCGC00024813-01; NCGC00024813-02; NCGC00024813-03; NCGC00024813-04; NCGC00024813-05; NCGC00024813-06; NCGC00024813-07; NCGC00024813-08; NCGC00024813-16; NCGC00024813-17; SBI-0050996.P003; AB00514695; AB00514695-07; AB00514695_08; BRD-K13994703-001-02-0; BRD-K13994703-003-04-2; BRD-K13994703-003-10-9; UNII-9Y8NXQ24VQ component AQHHHDLHHXJYJD-AWEZNQCLSA-N; (2S)-1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol; 1-((1-methylethyl)amino) 3-(1-naphthalenyloxy) 2-propanol; 2-Propanol,1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, (2S)-; [2-Hydroxy-3-(naphthalen-1-yloxy)-propyl]-isopropyl-ammonium((-)-propranolol)
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| Activity |
Ki = 170000 nM
|
[9] | |||
| Compound Name |
2-(Piperidin-1-ylmethyl)-2,3-dihydrochromen-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL223132; BDBM50207941
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||||
| Activity |
EC50 = 176300 nM
|
[24] | |||
| Compound Name |
Click to Show/Hide
|
Compound Info | |||
| Activity |
IC50 = 53900 nM
|
[3] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 31 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Vincristine
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Approved | Compound Info | ||
| Synonyms |
LCR; Leurocristine; Marqibo; Oncovine; Tecnocris; VCR; VIN; Vincasar; Vincristina; Vincristinum; Vincrstine; Vincrystine; Vinkristin; Indole alkaloid; Liposomal Vincristine; Onco TCS; Vincristina [DCIT]; Oncovin (TN); Tecnocris (TN); Vincristine (INN); Vincristine [INN:BAN]; Vincristinum [INN-Latin]; Lilly37231 (1:1 sulfate salt); Oncovin (1:1 sulfate salt); Vincasar (1:1 sulfate salt); Vincrex (1:1 sulfate salt); Vincaleukoblastine, 22-oxo-22-Oxovincaleukoblastine; Z-D-Val-Lys(Z)-OH; 22-Oxovincaleukoblastine
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| Activity |
Ki = 213000 nM
|
[12] | |||
| Compound Name |
Atorvastatin
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Approved | Compound Info | ||
| Synonyms |
Atogal; Atorlip; Atorpic; Atorvastatina; Atorvastatine; Atorvastatinium; Atrovastin; Cardyl; Faboxim; Lipotropic; Lipovastatinklonal; Liprimar; Lowden; Sincol; Sortis; Sotis; Torvacard; Torvast; Totalip; Tozalip; Tulip; Vastina; Xanator; Xarator; Xavator; Zurinel; Atorvastatin (INN); Atorvastatin [INN:BAN]; Lipitor (TN); Lipitor(TM); Sortis (TN); (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid; (betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid; 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
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| Activity |
IC50 = 271000 nM
|
[7] | |||
| Compound Name |
Fluconazole
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Approved | Compound Info | ||
| Synonyms |
Afungil; Alflucoz; Baten; Beagyne; Biocanol; Biozolene; Canzol; Cryptal; Diflazon; Diflucan; Dimycon; Elazor; FCZ; FLCZ; Flucazol; FlucoLich; Flucobeta; Fluconazol; Fluconazolum; Flucostat; Flukezol; Flunazul; Flunizol; Fluzone; Forcan; Fuconal; Fungata; Lavisa; Loitin; Mutum; Neofomiral; Oxifugol; Oxifungol; Pritenzol; Solacap; Syscan; TPF; Triflucan; Zemyc; Zoltec; Zonal; AbZ Brand of Fluconazole; Aliud Brand of Fluconazole; Alpharma Brand of Fluconazole; Apo Fluconazole; Apotex Brand of Fluconazole; Armstrong Brand of Fluconazole; Betapharm Brand of Fluconazole; Chemia Brand of Fluconazole; Ct Arzneimittel Brand of Fluconazole; Effik Brand of Fluconazole; Fluc Hexal; Fluconazol AL; Fluconazol AbZ; Fluconazol Isis; Fluconazol Stada; Fluconazol [Spanish]; Fluconazol ratiopharm; Fluconazol von ct; Fluconazolum [Latin]; Hexal Brand of Fluconazole; Lesvi Brand of Fluconazole; Lichtenstein Brand of Fluconazole; Mack Brand of Fluconazole; Pfizer Brand of Fluconazole; Pfleger Brand of Fluconazole; Ratiopharm Brand of Fluconazole; SAT Brand of Fluconazole; Silanes Brand of Fluconazole; Stada Brand of Fluconazole; Vita Brand of Fluconazole; F0677; Fluconazole in combination with MGCD290; UK 49858; UK49858; Alfumet (TN); Apo-Fluconazole; Ct-Arzneimittel Brand of Fluconazole; DIFLUCAN IN DEXTROSE 5% IN PLASTIC CONTAINER; DRG-0005; Diflucan (TN); Fluconazol-Isis; Fluconazol-ratiopharm; Fluconazole & Bovine Lactoferrin; Fluconazole & Human recombinant granulocyte colony stimulating factor; Fluconazole & hGCSF; Fluconazole in dextrose 5% in plastic container; Flucytosine & Nyotran; GL663142 & Fluconazole; KS-1059; Trican (TN); UK-49858; DIFLUCAN IN SODIUM CHLORIDE 0.9%; DIFLUCAN IN SODIUM CHLORIDE 0.9%IN PLASTIC CONTAINER; Fluconazole in sodium chloride 0.9%; Fluconazole in sodium chloride 0.9% in plastic container; Flucytosine & Nyotran(Liposomal Nystatin); XMP.284 & Fluconazole; XMP.366 & Fluconazole; XMP.391 & Fluconazole; Diflucan, Trican, Alfumet, Fluconazole; Fluconazole & MC-510,011; Fluconazole (JAN/USAN/INN); Fluconazole [USAN:INN:BAN:JAN]; 2,4-Difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol; 2,4-difluoro-,1-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol; 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL; 2-(2,4-Difluoro-phenyl)-1,3-bis-[1,2,4]triazol-1-yl-propan-2-ol; 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)-2-propanol; 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol; 2-(2,4-Difluorophenyl)-1,3-di-1H-1,2,4-triazol-1-ylpropan-2-ol; 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
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||||
| Activity |
Ki > 400000 nM
|
[4] | |||
| Compound Name |
Abacavir
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Approved | Compound Info | ||
| Synonyms |
Trizivir; Ziagen; Abacavir [INN]; Abacavir (INN); Ziagen (TN); Ziagen (TM)(*Succinate salt*); [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol; {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol; (+/-)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (+/-)-Abacavir; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; ABC
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| Activity |
IC50 > 500000 nM
|
[23] | |||
| Compound Name |
Propranolol
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Approved | Compound Info | ||
| Synonyms |
Anaprilin; Anapriline; Avlocardyl; Bedranol; Berkolol; Betachron; Betadren; Betalong; Caridolol; Corpendol; Dociton; Efektolol; Etalong; Euprovasin; Herzbase; Ikopal; Inderal; Inderalici; Inderex; Inderol; Intermigran; Kemi; Migrastat; Naprilin; Obsidan; Obzidan; Pranolol; Pronovan; Propanalol; Propanix; Propanolol; Propranalol; Propranololo; Propranololum; Proprasylyt; Reducor; Sawatal; Servanolol; Sumial; Beta Neg; Inderal hydrochloride; Kemi S; Propranolol Hcl Intensol; Propranololo [DCIT]; Racemic propranolol; Reducorline; AY 64043; AY-20694; Anaprilinum (TN); Avlocardyl (TN); Beta-Propranolol; Beta-Tablinen; Beta-Timelets; DL-Propranolol hydrochloride; Deralin (TN); Dociton (TN); Inderal (TN); Inderal LA (TN); Inderalici (TN); InnoPran XL (TN); Propanolol [INN-Spanish]; Propranolol (INN); Propranolol (TN); Propranolol [INN:BAN]; Propranololum [INN-Latin]; Sumial (TN); D,L-Propranolol; INDERIDE-40/25; R,S-Propranolol Hydrochloride; (+-)-Propranolol; (1)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol; (R)-(+)-propranolol; (S)-(-)-PROPRANOLOL; 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol; 1-(1-Naphthyloxy)-2-hydroxy-3-(isopropylamino)propane; 1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol; 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol; 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol; 1-(naphthalen-1-yloxy)-3-(propan-2-ylamino)propan-2-ol; 1-Isopropylamino-3-(1-naphthyloxy)-2-propanol; 1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol; 1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol; 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-(9CI); 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, (+-)-(9CI); 3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol
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| Activity |
IC50 = 583000 nM
|
[9] | |||
| Compound Name |
Oseltamivir
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Approved | Compound Info | ||
| Synonyms |
Tamiflu (*Phosphate salt 1:1*); Agucort; Oseltamivirum; Tamvir; GS 4104; GS4104; Agucort (TN); GS-4104; Oseltamivir (INN); Oseltamivir [INN:BAN]; Ro-640796; Tamiflu (TN); Tamiflu-Free; Ro-64-0796; OTV
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| Activity |
IC50 = 1300000 nM
|
[44] | |||
| Compound Name |
Imatinib
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Approved | Compound Info | ||
| Synonyms |
Cgp 57148; Glamox; Glamox (TN); Gleevec (TN); Glivec (TN); Imatinib (INN); Imatinib (STI571); Imatinib Methansulfonate; Imatinib [INN:BAN]; 112GI019; 152459-95-5; BKJ8M8G5HI; CCRIS 9076; CGP-57148; CHEMBL941; Imatinib free base; STI; UNII-BKJ8M8G5HI
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| Activity |
IC50 = 15135612484 nM
|
[6] | |||
| Compound Name |
Reserpine
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Approved | Compound Info | ||
| Synonyms |
Abesta; Abicol; Adelfan; Adelphin; Alkarau; Alkaserp; Alserin; Apoplon; Apsical; Ascoserp; Ascoserpina; Austrapine; Banasil; Banisil; Benazyl; Bioserpine; Brinderdin; Briserine; Broserpine; Cardioserpin; Carditivo; Carpacil; Carrserp; Darebon; Deserpine; Dralserp; Eberpine; Eberspine; Ebserpine; Elfanex; Elserpine; Enipresser; Escaspere; Eserpine; Eskaserp; Eskaserpine; Gammaserpine; Gilucard; Helfoserpin; Hexaplin; Hiposerpil; Hiserpia; Hydropine; Hydroserp; Hypersil; Hypersine; Hypertensan; Idoserp; Idsoserp; Interpina; Kitine; Klimanosid; Lemiserp; Loweserp; Mallopress; Maviserpin; Mayserpine; Mephaserpin; Modenol; Naquival; Nembuserpin; Neoserfin; Neoserp; Neoslowten; Orthoserpina; Perskleran; Pressimedin; Purserpine; Quiescin; Raucap; Raudiford; Raudixin; Raudixoid; Raugal; Raulen; Rauloydin; Raumorine; Raunervil; Raunorine; Raunova; Raupasil; Raupoid; Raurine; Rausan; Rausedan; Rausedil; Rausedyl; Rauserpin; Rauserpine; Rauserpol; Rausingle; Rautrin; Rauvlid; Rauwasedin; Rauwilid; Rauwiloid; Rauwipur; Rauwita; Rauwoleaf; Rawilid; Recipin; Regroton; Resaltex; Resedrex; Resedril; Reserbal; Resercaps; Resercen; Reserfia; Reserjen; Reserlor; Reserp; Reserpal; Reserpamed; Reserpanca; Reserpene; Reserpex; Reserpidefe; Reserpil; Reserpin; Reserpina; Reserpinum; Reserpka; Reserpoid; Reserpur; Reserutin; Resiatric; Residin; Residine; Resine; Resocalm; Resperin; Resperine; Respital; Restran; Rezerpin; Riserpa; Rivased; Rivasin; Rolserp; Roxel; Roxinoid; Roxynoid; Ryser; Salupres; Sandril; Sandron; Sedaraupin; Sedaraupina; Sederaupin; Sedserp; Seominal; Serfin; Serfolia; Serolfia; Serpalan; Serpaloid; Serpaneurona; Serpanray; Serpasil; Serpasol; Serpate; Serpazil; Serpazol; Serpedin; Serpen; Serpena; Serpentil; Serpentin; Serpentina; Serpicon; Serpil; Serpiloid; Serpilum; Serpine; Serpipur; Serpivate; Serpivite; Serpogen; Serpoid; Serpone; Serpyrit; Sertabs; Sertens; Sertensin; Sertina; Supergan; Tefaserpina; Temposerpine; Tensanyl; Tenserpinie; Tensional; Tensionorme; Tepserpine; Terbolan; Transerpin; Triserpin; Tylandril; Unilord; Unipres; VIXO; Esc aspere; Hydromox R; Hypercal B; Loweser p; Neose rfin; Rau sedyl; Renese R; Rese rpamed; Se rpate; V Serp; VI XO; Diupres 250; Diupres 500; ENT 50146; H 520; Hydropres 25; Hydropres 50; Hydrosine 25; R 0875; Apoplon (TN); Diupres-250; Diupres-500; Diurese-R; Diutensen-R; HYDRO-RESERP; Hydrap-ES; Hydromox-R; Key-serpine; L-Carpserp; Neo-serp; Rau-Sed; Renese-R; Rese-lar; Reser-ar; SK-Reserpine; T-Serp; Usaf cb-27; V-Serp; Vio-Serpine; Cam-Ap-Es; L"-Carpserp; R-e-s; Ser-A-Gen; 3P Reserp
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| Activity |
IC50 = 75857757503 nM
|
[6] | |||
| Compound Name |
Nicardipine
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Approved | Compound Info | ||
| Synonyms |
Nicardipino; Nicardipinum; Cardene IV; Nicardipine LA; Cardene (TN); Nicardipine (INN); Nicardipine [INN:BAN]; Nicardipino [INN-Spanish]; Nicardipinum [INN-Latin]; Y-93; Methyl 2-[methyl(phenylmethyl)amino]ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 2-(Benzylmethylamino)ethylmethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridine-3,5-dicarboxylate; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(benzylmethylamino)ethyl methyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-[methyl(phenylmethyl)amino]ethyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-(benzylmethylamino)ethyl methyl ester; 5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
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||||
| Activity |
IC50 = 2.75E+11 nM
|
[6] | |||
| Compound Name |
TPP+
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Investigative | Compound Info | ||
| Synonyms |
tetraphenylphosphonium
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| Activity |
IC50 = 426600 nM
|
[3] | |||
| Compound Name |
1-(benzyloxy)-2-(2-phenylethyl)benzene
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL215010; 1-(benzyloxy)-2-(2-phenylethyl)benzene; SCHEMBL4183309; 1-(benzyloxy)-2-phenethylbenzene
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| Activity |
EC50 > 1000000 nM
|
[18] | |||
| Compound Name |
2-Amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d][1,3]thiazin-4-one
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Investigative | Compound Info | ||
| Synonyms |
2-amino-5,6,7,8-tetrahydro-4H-[1]benzothieno[2,3-d][1,3]thiazin-4-one; SMR000011021; Oprea1_197655; Oprea1_401702; MLS000029292; CHEMBL452241; 2-Amino-5,6,7,8-tetrahydro-3,9-dithia-1-aza-fluoren-4-one; HMS1651F03; HMS2497G19; ZINC116154; STL079726; AKOS000531485; MCULE-6039383465; ST50131690; SR-01000443615; SR-01000443615-1; Q27186571; F0723-0017; 2-Amino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d][1,3]thiazin-4-one; 2-amino-5,6,7,8-tetrahydrobenzo[b]thiopheno[2,3-d]1,3-thiazin-4-one; 2-amino-5,6,7,8-tetrahydro-4H-benzo[4,5]thieno[2,3-d][1,3]thiazin-4-one
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| Activity |
IC50 > 200000 nM
|
[45] | |||
| Compound Name |
1-[2-(2-Hydroxy-3-morpholin-4-ylpropoxy)phenyl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222401; Ethanone, 1-[2-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]-; ACMC-20muqf; CTK0F4899; DTXSID10388008; BDBM50370890; AKOS002762866; AKOS016134054; MCULE-4638926150
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| Activity |
EC50 = 207000 nM
|
[24] | |||
| Compound Name |
3-[4-(4-Methoxyphenyl)-5-sulfanylidene-1H-1,2,4-triazol-3-yl]-4,5-dihydro-1H-pyridazin-6-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL224966; BDBM50370893
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| Activity |
EC50 > 250000 nM
|
[24] | |||
| Compound Name |
(4Z)-2,5-Dimethyl-4-[phenyl(propylamino)methylene]-2,4-dihydro-3H-pyrazol-3-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL131829; CHEMBL3144687; BDBM50067132; 2,5-Dimethyl-4-[1-phenyl-1-propylamino-meth-(Z)-ylidene]-2,4-dihydro-pyrazol-3-one; 3H-pyrazol-3-one, 2,4-dihydro-2,5-dimethyl-4-[phenyl(propylamino)methylene]-, (4Z)-
Click to Show/Hide
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||||
| Activity |
EC50 = 272500 nM
|
[35] | |||
| Compound Name |
Ethanone, 1-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]-
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL146671; ACMC-20muqe; CTK0F4900; DTXSID80392814; BDBM50134981; STK966299; AKOS001655227; AKOS016287591; MCULE-8954041924; ST45175351; 4'-(2-Hydroxy-3-morpholinopropoxy)acetophenone; 1-(4-(2-hydroxy-3-morpholinopropoxy)phenyl)ethanone; 1-acetyl-4-(2-hydroxy-3-morpholin-4-ylpropoxy)benzene; 1-[4-(2-Hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone; 1-{4-[2-hydroxy-3-(morpholin-4-yl)propoxy]phenyl}ethanone
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||||
| Activity |
EC50 = 302100 nM
|
[24] | |||
| Compound Name |
2-Ethoxyethyl 4-aminobenzoate
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Investigative | Compound Info | ||
| Synonyms |
ethoxyethyl 4-aminobenzoate; CHEMBL221472; SCHEMBL9069012; ZINC1771478; BDBM50370898; SBB043658; STK961734; AKOS000274114; MCULE-3910534481; ST50188793
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||||
| Activity |
EC50 = 311800 nM
|
[24] | |||
| Compound Name |
Celiprolol
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Investigative | Compound Info | ||
| Synonyms |
Selectol; Celiprololum; Celectol; ST-1396; 3-[3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-1,1-diethylurea; Celiprolol [INN:BAN]; 3-(3-acetyl-4-(3-(tert-butylamino)-2-hydroxypropoxy)phenyl)-1,1-diethylurea; Celiprololum [INN-Latin]; CCRIS 3400; RHC-5320A; RHC 5320 A; EINECS 260-497-7; UL/1677; BRN 2776298; Edsivo; (-)-Celiprolol; Celiprolol (INN); ST1396; Celiprolol PCH (TN); SCHEMBL49415; CHEMBL27810; GTPL9064; DTXSID3020259; CTK6E6992; REV 5320; BDBM50470842; AKOS015917778; DB04846; 3-[3-acetyl-4-[3-(tert-butylamino)-2-hydroxy-propoxy]phenyl]-1,1-diethyl-urea; NCGC00344562-02; SC-16115; DB-052996; D07660; 980C939; L013433; Q420586; BRD-A95602221-003-01-3
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||||
| Activity |
Ki = 313000 nM
|
[46] | |||
| Compound Name |
Quinidine
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Investigative | Compound Info | ||
| Synonyms |
(+)-Quinidine; Conchinin; Chinidin; Pitayine; beta-Quinine; (8R,9S)-Quinidine; (9S)-6'-Methoxycinchonan-9-ol; Cin-Quin; Conquinine; Quinidex; Kinidin; Conchinine; chinidinum; quinidina; Quiniduran; Chinidine; Cinchonan-9-ol, 6'-methoxy-, (9S)-; UNII-ITX08688JL; Quinaglute; Auriquin; Quinidine sulfate; MFCD00135581; Quinicardine; CHEMBL1294; Cardioquin; ITX08688JL; QUINIDINE HYDROCHLORIDE; Biquin durules; Quinidine sulphate; beta-Quinidine; (3'.alpha., 9S)-6'-Methoxycinchonan-9-ol; Quinidine, 98%, anhydrous; TCMDC-131239; NCI-C56246; (8R,9S)-6'-Methoxycinchonan-9-ol; Chinidin [German]; SMR000857275; Quinidine [BAN:NF]; Quinindine; CCRIS 672; HSDB 225; EINECS 200-279-0; Quinidine, anhydrous; PubChem7994; Prestwick3_000280; bmse000511; Epitope ID:141803; SCHEMBL15943; BSPBio_000160; MLS001335913; MLS001335914; MLS002548869; BPBio1_000176; GTPL2342; DTXSID4023549; SCHEMBL17537608; HMS2234L10; HMS3259O09; ACT09863; HY-B1751; ZINC3831405; BDBM50121975; RW2069; AKOS015920101; CCG-256507; CS-7812; DB00908; MCULE-7178915526; NC00478; SDCCGMLS-0066600.P001; NCGC00091231-01; NCGC00091231-02; NCGC00091231-03; AS-30538; BR-57138; SC-05389; SC-88763; AB00514657; 6470-EP1441224A2; 6470-EP2272835A1; 6470-EP2272844A1; 6470-EP2272972A1; 6470-EP2272973A1; 6470-EP2275411A2; 6470-EP2277872A1; 6470-EP2305655A2; 6470-EP2314576A1; 6470-EP2314585A1; M-7594; AB01562940_01; Q412496; W-109256; BRD-K59632282-052-01-5; BRD-K59632282-052-02-3; BRD-K70799801-311-02-7
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||||
| Activity |
IC50 = 340000 nM
|
[9] | |||
| Compound Name |
Dihydroergocryptine
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Investigative | Compound Info | ||
| Synonyms |
Dihydro-alpha-ergocryptine; Dihydroergocriptine; alpha-Dihydroergocryptine; UNII-202229IR8Y; 9,10-dihydro-alpha-ergocryptine; Alpha-Dihydroergocriptine; CHEMBL1743263; 202229IR8Y; EINECS 246-993-6; NCGC00183332-01; dihydro- -ergocryptine; DSSTox_CID_28615; DSSTox_RID_82885; DSSTox_GSID_48689; SCHEMBL233373; DTXSID5048689; BDBM81453; ZINC3929793; Tox21_113078; BDBM50390994; PDSP2_001088; DB11274; NSC_159729; D07835; Q905717; UNII-34HPE9Z8IP component PBUNVLRHZGSROC-VTIMJTGVSA-N; UNII-67V3FSL2GL component PBUNVLRHZGSROC-VTIMJTGVSA-N
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||||
| Activity |
Ki = 360500 nM
|
[4] | |||
| Compound Name |
4-Iodo-1-methyl-N'-(2-methylpyrazole-3-carbonyl)pyrazole-3-carbohydrazide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222605; ZINC997286; BDBM50370884; AKOS003763326; MCULE-9810033602
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||||
| Activity |
EC50 > 500000 nM
|
[24] | |||
| Compound Name |
(E)-3-(3-Iodo-4,5-dimethoxyphenyl)-1-naphthalen-2-ylprop-2-en-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3926291; BDBM50195539
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||||
| Activity |
IC50 > 500000 nM
|
[47] | |||
| Compound Name |
(E)-3-(3-Bromo-4,5-dimethoxyphenyl)-1-naphthalen-2-ylprop-2-en-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3898212; BDBM50195540
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||||
| Activity |
IC50 > 500000 nM
|
[47] | |||
| Compound Name |
Methyleugenolglycol
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Investigative | Compound Info | ||
| Synonyms |
3-(3,4-dimethoxyphenyl)propane-1,2-diol; CHEMBL376901; 3-(3,4-dimethoxyphenyl)-1,2-propanediol; 3-(3,4-dimethoxyphenyl)-propane-1,2-diol; 2,3-Propanediol, 1-(3,4-dimethoxyphenyl)-; Oprea1_146476; SCHEMBL9561046; DTXSID70949371; BDBM50370887; AKOS025288302; MCULE-8391710743; AI-942/13331556
Click to Show/Hide
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||||
| Activity |
EC50 > 500000 nM
|
[24] | |||
| Compound Name |
(E)-3-(3-Chloro-4,5-dimethoxyphenyl)-1-naphthalen-2-ylprop-2-en-1-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3891465; BDBM50195544
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||||
| Activity |
IC50 > 500000 nM
|
[47] | |||
| Compound Name |
Dihydroergocristine
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Investigative | Compound Info | ||
| Synonyms |
9,10-Dihydroergocristine; UNII-05D48LUM4Z; GNF-Pf-3462; Ergocristine, dihydro-; Dihydroergocristin; 05D48LUM4Z; CHEMBL601773; NCGC00017401-02; DSSTox_CID_26322; DSSTox_RID_81538; DSSTox_GSID_46322; Ergocristine, 9,10-dihydro-; CCRIS 4027; EINECS 241-493-4; SR-01000075381; NCGC00163163-01; Prestwick0_000562; Prestwick1_000562; Prestwick2_000562; Prestwick3_000562; Dihydroergocristine (BAN); Lopac0_000409; BSPBio_000344; SCHEMBL146691; SPBio_002563; BPBio1_000380; DTXSID3046322; HMS2090H10; ZINC3995616; Tox21_112021; Tox21_113115; BDBM50390992; 5'-Benzyl-9,10-dihydro-12'-hydroxy-2'-isopropyl-3',6',18-ergotamantrion; CCG-204502; DB13345; 9,10-Dihydro-12'-hydroxy-2'-isopropyl-5'alpha-benzylergotaman-3',6',18-trion; NCGC00017401-06; NCGC00017401-07; NCGC00017401-08; NCGC00017401-09; NCGC00017401-10; NCGC00023148-04; NCGC00023148-05; NCGC00023148-06; D07834; Q5276428; SR-01000075381-5; BRD-K97440753-066-03-3; UNII-34HPE9Z8IP component DEQITUUQPICUMR-HJPBWRTMSA-N
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||||
| Activity |
Ki = 511000 nM
|
[4] | |||
| Compound Name |
Propranolol
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Investigative | Compound Info | ||
| Synonyms |
Propanolol; beta-Propranolol; Avlocardyl; Dociton; Anapriline; Betalong; Euprovasin; Propanalol; Proprasylyt; Propanix; Reducor; Inderal; propranololo; Corpendol; Sawatal; Sumial; Propranololum; Obsidan; Berkolol; Caridolol; 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol; CHEMBL27; 1-Isopropylamino-3-(1-naphthyloxy)-2-propanol; 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-; Betadren; Angilol; Apsolol; Beprane; Cardinol; Deralin; Duranol; Frekven; Inderex; Inderol; Indobloc; Pranolol; Prophylux; Propranur; Pylapron; Rapynogen; Sagittol; Sloprolol; Elbrol; Oposim; Tesnol; Racemic propranolol; Inderal La; Prano-Puren; beta-NEG; Inderal hydrochloride; D,L-Propranolol; 3-[(methylethyl)amino]-1-naphthyloxypropan-2-ol; (+-)-Propranolol; Propranololo [DCIT]; hemangiol; Propranolol, L-; Propranalol; Bedranol; dl-propranolol; Propranolol [INN:BAN]; AY 20694; Propanolol [INN-Spanish]; Propranololum [INN-Latin]; racemic-Propranolol; (R)-Propranolol (hydrochloride); NSC91523; CCRIS 3082; AY-20694; EINECS 208-378-0; EINECS 235-867-6; b-Propranolol; Propranolol (TN); .beta.-Propranolol; Propranolol (INN); Dociton (Salt/Mix); Inderal (Salt/Mix); Obsidan (Salt/Mix); Propanolol,(+/-); PROPRANOLOL, d; Avlocardyl (Salt/Mix); beta-Propranolol;Dociton; Propranolol Hcl Intensol; PROPANOLOL(-); Prestwick0_000952; Prestwick1_000952; Prestwick2_000952; Prestwick3_000952; PROPRANOLOL,(+); PROPRANOLOL,(-); Spectrum2_001301; Spectrum2_001699; Spectrum3_000883; Spectrum3_001071; Spectrum4_000974; Spectrum4_001222; Spectrum5_000751; (.+/-.)-Propranolol; SCHEMBL3955; Lopac0_000896; Oprea1_304193; BSPBio_000944; BSPBio_002682; CBDivE_006180; GTPL564; KBioGR_001347; KBioGR_001684; KBioGR_002515; KBioSS_002523; ARONIS27011; DivK1c_000023; (1)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol; SPBio_001361; SPBio_001658; SPBio_003093; BPBio1_001040; ICI 45520 (Salt/Mix); NSC 91523 (Salt/Mix); DTXSID6023525; SCHEMBL12264958; BDBM25761; CTK8I6896; HY-B0573B; KBio1_000023; KBio2_002515; KBio2_005083; KBio2_007651; KBio3_001766; KBio3_001902; KBio3_002993; cMAP_000071; NINDS_000023; (A+/-)-Propranolol hydrochloride; Bio1_000367; Bio1_000856; Bio1_001345; HMS2090L21; HMS3428G03; ALBB-023324; BCP26001; BCP31343; KS-00002WT3; BBL023437; PDSP1_000767; PDSP1_001607; PDSP1_001608; PDSP2_000755; PDSP2_001591; PDSP2_001592; STK735510; AKOS000588816; AKOS016050338; CCG-103643; DB00571; FE-0204; MCULE-7804628650; SDCCGSBI-0050871.P004; IDI1_000023; NCGC00015798-04; NCGC00015798-05; NCGC00015798-06; NCGC00015798-07; NCGC00015798-08; NCGC00015798-09; NCGC00015798-19; NCGC00024690-02; NCGC00024690-03; ST024757; SBI-0050871.P003; AB0108847; AY-64043-; AB00053537; CS-0069968; FT-0650563; FT-0674088; T7896; EN300-40731; C07407; D08443; AB00053537-10; AB00053537_11; AB00053537_12; 1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol; 525P666; L000679; Q423364; 1-(alpha-naphthoxy)-3-(isopropylamino)-2-propanol; W-109550; BRD-A10070317-003-06-9; BRD-A10070317-003-17-6; F0001-3681
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||||
| Activity |
IC50 = 573000 nM
|
[9] | |||
| Compound Name |
3-[[2-[2-(3-Methoxyphenyl)ethyl]phenoxy]methyl]pyridine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL217281; 3-({2-[2-(3-methoxyphenyl)ethyl]phenoxy}methyl)pyridine; SCHEMBL4182028; BDBM50197196; 3-((2-(3-methoxyphenethyl)phenoxy)methyl)pyridine
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||||
| Activity |
EC50 > 1000000 nM
|
[18] | |||
| Compound Name |
2-(2-(3-Phenylpropanoyl)phenoxy)acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL223590; BDBM50207963
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||||
| Activity |
EC50 = 1588000 nM
|
[24] | |||
| Compound Name |
N-[2-[[4-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoylamino]phenyl]quinoline-3-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL248480; BDBM50411588
Click to Show/Hide
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||||
| Activity |
IC50 = 3.98E+11 nM
|
[6] | |||
| Compound Name |
N-(2-((4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)carbamoyl)phenyl)-3,4-dimethoxybenzamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
WK-X-34; CHEMBL247473; BDBM50305080
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||||
| Activity |
IC50 = 7.76E+11 nM
|
[6] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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