Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O5NK
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| Former ID |
DAP000714
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| Drug Name |
Oseltamivir
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| Synonyms |
Tamiflu (*Phosphate salt 1:1*); Agucort; Oseltamivirum; Tamvir; GS 4104; GS4104; Agucort (TN); GS-4104; Oseltamivir (INN); Oseltamivir [INN:BAN]; Ro-640796; Tamiflu (TN); Tamiflu-Free; Ro-64-0796; OTV
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| Drug Type |
Small molecular drug
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| Indication | Influenza virus infection [ICD-11: 1E30-1E32] | Approved | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Company |
Hoffmann-La Roche pharmaceutical company
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H28N2O4
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| Canonical SMILES |
CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)OCC
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| InChI |
1S/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1
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| InChIKey |
VSZGPKBBMSAYNT-RRFJBIMHSA-N
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| CAS Number |
CAS 196618-13-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10292, 626306, 7980209, 8034664, 8189453, 14825762, 14898934, 43121870, 46507602, 49958481, 50123365, 53789667, 57315247, 58106749, 75193389, 85789649, 92309047, 93166584, 96024993, 103375662, 104332669, 117576917, 118048381, 124893596, 126657793, 126681234, 126733879, 134338002, 135023115, 135811666, 137002940, 137236650, 140589553, 151982861, 152099920, 152258534, 160647368, 160963546, 164786722, 164831566, 165702338, 174006818, 175267600, 176484257, 179116828, 184546341, 185976796, 196109901, 211535901, 223556618
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| ChEBI ID |
CHEBI:7798
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| ADReCS Drug ID | BADD_D01627 ; BADD_D01628 | |||
| SuperDrug ATC ID |
J05AH02
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| SuperDrug CAS ID |
cas=196618130
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| Drug Resistance Mutation (DRM) | Top | |||
|---|---|---|---|---|
| DRM | DRM Info | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Influenza Neuraminidase (Influ NA) | Target Info | Inhibitor | [2], [3] |
| KEGG Pathway | Other glycan degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 2 | Current and future antiviral therapy of severe seasonal and avian influenza. Antiviral Res. 2008 Apr;78(1):91-102. | |||
| REF 3 | Antiviral agents for influenza, hepatitis C and herpesvirus, enterovirus and rhinovirus infections. Med J Aust. 2001 Jul 16;175(2):112-6. | |||
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