| References |
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| REF 1 |
Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region. J Biol Chem. 2006 Sep 29;281(39):28605-14.
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| REF 2 |
Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. Science. 1996 Jul 12;273(5272):239-42.
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| REF 3 |
Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR). J Biol Chem. 2005 Jan 14;280(2):1037-43.
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| REF 4 |
COMP-Ang1 Potentiates EPC Treatment of Ischemic Brain Injury by Enhancing Angiogenesis Through Activating AKT-mTOR Pathway and Promoting Vascular Migration Through Activating Tie2-FAK Pathway. Exp Neurobiol. 2015 Mar;24(1):55-70.
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| REF 5 |
Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase. J Biol Chem. 2005 Jul 8;280(27):25485-90.
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| REF 6 |
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell. 2006 Oct 6;127(1):125-37.
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| REF 7 |
Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin. J Biol Chem. 2003 Sep 5;278(36):33637-44.
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| REF 8 |
TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy. Autophagy. 2015;11(7):1052-62.
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| REF 9 |
mTOR generates an auto-amplification loop by triggering the TrCP- and CK1-dependent degradation of DEPTOR. Mol Cell. 2011 Oct 21;44(2):317-24.
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| REF 10 |
Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38. Science. 2007 Nov 9;318(5852):977-80.
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| REF 11 |
Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. Mol Cell Biol. 2006 Jan;26(1):63-76.
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