Drug Information

Drug General Information
Drug ID
D0A1DU
Former ID
DNC002503
Drug Name
Pyrophosphate 2-
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551374]
Structure
Download
2D MOL

3D MOL
Formula
H2O7P2-2
Canonical SMILES
OP(=O)([O-])OP(=O)(O)[O-]
InChI
1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-2
InChIKey
XPPKVPWEQAFLFU-UHFFFAOYSA-L
PubChem Compound ID
4995
PubChem Substance ID
7437608, 7889993, 26697122, 29224068, 46508771, 80399921, 104307977, 124955076, 126408044, 137801774, 160965419
Target and Pathway
Target(s) NH(3)-dependentNAD(+) synthetase Target Info Inhibitor [551374]
RNA-dependentRNA polymerase Target Info Inhibitor [551374]
Hypoxanthine-guanine-xanthine phosphoribosyltransferase Target Info Inhibitor [551374]
6-phosphogluconate dehydrogenase, decarboxylating Target Info Inhibitor [551374]
Angiogenin Target Info Inhibitor [551374]
Hypoxanthine-guanine phosphoribosyltransferase Target Info Inhibitor [551374]
GMP synthase [glutamine-hydrolyzing] Target Info Inhibitor [551374]
BioCyc Pathway Pentose phosphate pathway
Pentose phosphate pathway (oxidative branch)PWY-7228:Guanosine nucleotides de novo biosynthesis
Superpathway of purine nucleotide salvage
Purine nucleotides de novo biosynthesis
Guanosine ribonucleotides de novo biosynthesis
KEGG Pathway Pentose phosphate pathway
Glutathione metabolism
Metabolic pathways
Biosynthesis of antibiotics
Carbon metabolismhsa00230:Purine metabolism
Drug metabolism - other enzymes
Metabolic pathwayshsa00230:Purine metabolism
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Pentose phosphate pathwayP02738:De novo purine biosynthesis
PathWhiz Pathway Warburg EffectPW000052:Purine MetabolismPW000003:Glutamate Metabolism
Purine Metabolism
Reactome Adherens junctions interactionsR-HSA-74217:Purine salvageR-HSA-73817:Purine ribonucleoside monophosphate biosynthesis
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Metabolism of carbohydrates
Pentose Phosphate PathwayWP404:Nucleotide Metabolism
Mesodermal Commitment Pathway
Endoderm Differentiation
Metabolism of nucleotidesWP1851:Metabolism of nucleotides
References
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.