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REF 1 |
XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3. Cell Signal. 2009 Dec;21(12):1857-65.
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REF 2 |
Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling. J Cell Sci. 2018 May 22;131(10). pii: jcs210575.
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REF 3 |
Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol. 2007;3:89.
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REF 4 |
Role of STRAP in regulating GSK3 function and Notch3 stabilization. Cell Cycle. 2011 May 15;10(10):1639-54.
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REF 5 |
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep. 2016 Nov 22;17(9):2488-2501.
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REF 6 |
A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3... J Biol Chem. 2002 Oct 4;277(40):36955-61.
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REF 7 |
Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta. Biochim Biophys Acta. 2009 Oct;1793(10):1597-603.
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REF 8 |
C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances. Oncogene. 2013 Jun 20;32(25):3101-10.
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REF 9 |
Stimulatory effect of -synuclein on the tau-phosphorylation by GSK-3. FEBS J. 2011 Dec;278(24):4895-904.
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REF 10 |
Vimentin is a novel AKT1 target mediating motility and invasion. Oncogene. 2011 Jan 27;30(4):457-70.
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REF 11 |
Purification and characterization of recombinant CH3 domain fragment of the CREB-binding protein. Protein Expr Purif. 2010 Apr;70(2):196-205.
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REF 12 |
Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35.
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REF 13 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep. 2013 Apr 25;3(4):1306-20.
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REF 14 |
Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):11960-5.
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REF 15 |
NUB1 modulation of GSK3 reduces tau aggregation. Hum Mol Genet. 2012 Dec 15;21(24):5254-67.
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REF 16 |
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. J Biol Chem. 2004 Feb 6;279(6):4869-76.
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REF 17 |
Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase. FEBS Lett. 1998 Sep 25;436(1):28-34.
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REF 18 |
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments. Biochemistry. 1999 Mar 23;38(12):3549-58.
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REF 19 |
Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation. Eur J Biochem. 1998 Mar 15;252(3):542-52.
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REF 20 |
Phosphorylation of human microtubule-associated protein tau by protein kinases of the AGC subfamily. FEBS Lett. 2007 Jun 12;581(14):2657-62.
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REF 21 |
Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta. FEBS Lett. 2002 Oct 23;530(1-3):209-14.
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REF 22 |
Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: implications for the mechanism of tau aggregation. J Neurochem. 2009 Jan;108(1):33-43.
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REF 23 |
Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains. FEBS Lett. 2009 Jul 7;583(13):2194-200.
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REF 24 |
PKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners. FEBS Lett. 2006 Nov 13;580(26):6269-74.
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REF 25 |
Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7951-5.
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REF 26 |
Phosphorylation of ataxin-3 by glycogen synthase kinase 3beta at serine 256 regulates the aggregation of ataxin-3. Biochem Biophys Res Commun. 2007 Jun 1;357(2):487-92.
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REF 27 |
A directed protein interaction network for investigating intracellular signal transduction. Sci Signal. 2011 Sep 6;4(189):rs8.
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REF 28 |
The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth. Biochim Biophys Acta. 2012 Aug;1823(8):1233-41.
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REF 29 |
Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. J Biol Chem. 2011 Sep 30;286(39):34088-100.
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REF 30 |
Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev Cell. 2006 Aug;11(2):213-23.
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REF 31 |
Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling. PLoS One. 2008;3(12):e4046.
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REF 32 |
Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol. 2004 Oct;6(10):931-40.
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REF 33 |
Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell. 2009 May 5;15(5):416-28.
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REF 34 |
GSK3 controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug. Oncogene. 2014 Jun 12;33(24):3172-82.
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REF 35 |
Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16654-9.
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REF 36 |
PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells. Mol Biol Cell. 2007 Mar;18(3):1118-27.
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REF 37 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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REF 38 |
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Nat Methods. 2013 Apr;10(4):307-14.
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REF 39 |
Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level. Genes Cells. 1998 Jun;3(6):395-403.
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REF 40 |
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin. EMBO J. 1999 May 4;18(9):2401-10.
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REF 41 |
Induction of Gsk3--TrCP interaction is required for late phase stabilization of -catenin in canonical Wnt signaling. J Biol Chem. 2014 Mar 7;289(10):7099-108.
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REF 42 |
Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1). J Biol Chem. 2003 Apr 18;278(16):13995-4001.
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REF 43 |
The SIAH E3 ubiquitin ligases promote Wnt/-catenin signaling through mediating Wnt-induced Axin degradation. Genes Dev. 2017 May 1;31(9):904-915.
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REF 44 |
Wnt signaling during BMP-2 stimulation of mesenchymal chondrogenesis. J Cell Biochem. 2002;84(4):816-31.
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REF 45 |
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability. Mol Cell Biol. 1999 Jun;19(6):4414-22.
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REF 46 |
The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. Curr Biol. 1999 Feb 25;9(4):207-10.
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REF 47 |
Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation. J Biol Chem. 2015 May 29;290(22):14120-9.
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REF 48 |
APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase. Mol Cell. 2008 Dec 5;32(5):652-61.
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REF 49 |
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell. 2005 Jul 22;19(2):159-70.
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REF 50 |
ER stress inhibits mTORC2 and Akt signaling through GSK-3-mediated phosphorylation of rictor. Sci Signal. 2011 Feb 22;4(161):ra10.
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REF 51 |
GSK-3 controls NF-kappaB activity via IKK/NEMO. Sci Rep. 2016 Dec 8;6:38553.
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REF 52 |
The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin. J Biol Chem. 2001 Mar 2;276(9):6061-4.
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REF 53 |
The interaction between beta-catenin, GSK3beta and APC after motogen induced cell-cell dissociation, and their involvement in signal transduction p... Int J Oncol. 2001 Apr;18(4):843-7.
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REF 54 |
The tuberin-hamartin complex negatively regulates beta-catenin signaling activity. J Biol Chem. 2003 Feb 21;278(8):5947-51.
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REF 55 |
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell. 2006 Sep 8;126(5):955-68.
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