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| Protein General Information (TTD Target) |
Top |
| Full Name |
LDL receptor related protein-6 (LRP-6)
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Clinical trial
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Target Info
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| UniProt ID |
LRP6_HUMAN
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| Gene Name |
LRP6
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| Gene ID |
4040
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| References |
Top |
| REF 1 |
Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev Cell. 2006 Aug;11(2):213-23.
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| REF 2 |
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol. 2001 Jun 26;11(12):951-61.
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| REF 3 |
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. J Biol Chem. 2005 Jul 22;280(29):26770-5.
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