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Target General Information |
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Target ID |
T56697 |
Target Info
|
Target Name |
Dickkopf-related protein 1 (DKK1) |
Synonyms |
hDkk1; hDkk-1; UNQ492/PRO1008; Dkk1; Dkk-1; Dickkopfrelated protein 1; Dickkopf1; Dickkopf-1 |
Target Type |
Clinical trial Target |
Gene Name |
DKK1 |
Biochemical Class |
Dickkopf protein |
UniProt ID |
|
Target Interacting Proteins |
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Putative transporters |
[+] 1 Putative transporters |
+ |
Interacting Target Name |
LDL receptor related protein-6 (LRP-6) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Low-density lipoprotein receptor-related protein 6 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[1] |
2 |
Affinity Capture-MS |
[2] |
3 |
Reconstituted Complex |
[3] |
References |
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REF 1 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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REF 2 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
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REF 3 |
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol. 2001 Jun 26;11(12):951-61.
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