Protein-Protein Interaction Details
| Protein General Information | Top | ||||
|---|---|---|---|---|---|
| Full Name | Adenomatous polyposis coli protein (APC) | ||||
| UniProt ID | APC_HUMAN | ||||
| Gene Name | APC | ||||
| Gene ID | 324 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Beta-catenin (CTNNB1) | Target Info | PPI Info | [1] | |
| Interacting Clinical trial Target(s) | Glycogen synthase kinase-3 beta (GSK-3B) | Target Info | PPI Info | [2] | |
| Interacting Patented-recorded Target(s) | BUB1 mitotic checkpoint serine/threonine kinase (BUB1) | Target Info | PPI Info | [3] | |
| Interacting Literature-reported Target(s) | Junction plakoglobin (JUP) | Target Info | PPI Info | [4] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Expression and interaction of different catenins in colorectal carcinoma cells. Int J Mol Med. 2001 Dec;8(6):695-8. | ||||
| REF 2 | The interaction between beta-catenin, GSK3beta and APC after motogen induced cell-cell dissociation, and their involvement in signal transduction p... Int J Oncol. 2001 Apr;18(4):843-7. | ||||
| REF 3 | A role for the Adenomatous Polyposis Coli protein in chromosome segregation. Nat Cell Biol. 2001 Apr;3(4):429-32. | ||||
| REF 4 | Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation. Biochem Biophys Res Commun. 1994 Aug 30;203(1):519-22. | ||||
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