Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T68547 Target Info
Target Name Histone deacetylase 1 (HDAC1)
Synonyms RPD3L1; HD1
Target Type Successful Target
Gene Name HDAC1
Biochemical Class Carbon-nitrogen hydrolase
UniProt ID
HDAC1_HUMAN 
Target Interacting Proteins  Top
Acid anhydride hydrolases [+] 3 Acid anhydride hydrolases +
Interacting Protein Name Chromodomain-helicase-DNA-binding protein 4 (CHD4) Interacting Protein Interacting Protein Info
UniProt ID
CHD4_HUMAN 
Synonyms CHD.4; Mi.2b; Mi2.BETA
Evidence Score (E-score) 17 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [5]
6 Affinity Capture-MS [6]
7 Affinity Capture-MS [7]
8 Affinity Capture-MS [8]
9 Affinity Capture-MS [9]
10 Affinity Capture-Western [10]
11 Affinity Capture-Western [11]
12 Affinity Capture-Western [6]
13 Affinity Capture-Western [7]
14 Affinity Capture-Western [9]
15 Affinity Capture-Western [12]
16 Affinity Capture-Western [13]
17 Reconstituted Complex [9]
Interacting Protein Name Chromodomain-helicase-DNA-binding protein 3 (CHD3) Interacting Protein Interacting Protein Info
UniProt ID
CHD3_HUMAN 
Synonyms Mi.2a; Mi2.ALPHA; ZFH
Evidence Score (E-score) 8 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Affinity Capture-MS [5]
5 Affinity Capture-MS [6]
6 Affinity Capture-Western [10]
7 Affinity Capture-Western [6]
8 Affinity Capture-Western [14]
Interacting Protein Name Lymphoid-specific helicase (HELLS) Interacting Protein Interacting Protein Info
UniProt ID
HELLS_HUMAN 
Synonyms LSH; PASG; SMARCA6
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [15]
2 Affinity Capture-Western [16]
3 Co-localization [15]
Acyltransferases [+] 2 Acyltransferases +
Interacting Target Name Histone acetyltransferase p300 (EP300) Clinical trial Target Interacting Protein Info
UniProt ID
EP300_HUMAN 
Synonyms Protein propionyltransferase p300; p300 HAT; P300; Histone crotonyltransferase p300; Histone butyryltransferase p300; E1A-associated protein p300; E1Aassociated protein p300
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [17]
2 Affinity Capture-Western [18]
3 Biochemical Activity [19]
4 Reconstituted Complex [18]
Interacting Target Name Transcription intermediary factor 1-beta (TRIM28) Literature-reported Target Interacting Protein Info
UniProt ID
TIF1B_HUMAN 
Synonyms Tripartite motif-containing protein 28; TIF1-beta; TIF1B; RNF96; RING-type E3 ubiquitin transferase TIF1-beta; RING finger protein 96; Nuclear corepressor KAP-1; KRIP-1; KRAB-interacting protein 1; KRAB-associated protein 1; KAP-1; KAP1; E3 SUMO-protein ligase TRIM28
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [20]
2 Affinity Capture-Western [21]
3 Co-fractionation [22]
Beta-transducin repeats [+] 4 Beta-transducin repeats +
Interacting Protein Name Histone-binding protein RBBP4 (RBBP4) Interacting Protein Interacting Protein Info
UniProt ID
RBBP4_HUMAN 
Synonyms NURF55; RBAP48; lin.53
Evidence Score (E-score) 20 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [5]
6 Affinity Capture-MS [6]
7 Affinity Capture-MS [8]
8 Affinity Capture-MS [9]
9 Affinity Capture-Western [23]
10 Affinity Capture-Western [24]
11 Affinity Capture-Western [25]
12 Affinity Capture-Western [26]
13 Affinity Capture-Western [11]
14 Affinity Capture-Western [6]
15 Affinity Capture-Western [7]
16 Affinity Capture-Western [9]
17 Affinity Capture-Western [12]
18 Affinity Capture-Western [27]
19 Affinity Capture-Western [28]
20 Affinity Capture-Western [29]
Interacting Protein Name Histone-binding protein RBBP7 (RBBP7) Interacting Protein Interacting Protein Info
UniProt ID
RBBP7_HUMAN 
Synonyms RbAp46
Evidence Score (E-score) 14 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Affinity Capture-MS [6]
5 Affinity Capture-MS [8]
6 Affinity Capture-MS [9]
7 Affinity Capture-Western [30]
8 Affinity Capture-Western [24]
9 Affinity Capture-Western [7]
10 Affinity Capture-Western [9]
11 Affinity Capture-Western [31]
12 Affinity Capture-Western [32]
13 Co-fractionation [33]
14 Co-purification [34]
Interacting Target Name Embryonic ectoderm development protein (EED) Clinical trial Target Interacting Protein Info
UniProt ID
EED_HUMAN 
Synonyms WD protein associating with integrin cytoplasmic tails 1; WAIT-1; hEED; Embryonic ectoderm development protein
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [2]
2 Affinity Capture-Western [35]
Interacting Target Name WD repeat-containing protein 5 (WDR5) Literature-reported Target Interacting Protein Info
UniProt ID
WDR5_HUMAN 
Synonyms BMP2-induced 3-kb gene protein; BIG3
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-Western [36]
Carbon-nitrogen hydrolases [+] 2 Carbon-nitrogen hydrolases +
Interacting Target Name Histone deacetylase 2 (HDAC2) Clinical trial Target Interacting Protein Info
UniProt ID
HDAC2_HUMAN 
Synonyms HD2
Evidence Score (E-score) 20 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [6]
6 Affinity Capture-MS [7]
7 Affinity Capture-MS [9]
8 Affinity Capture-Western [24]
9 Affinity Capture-Western [37]
10 Affinity Capture-Western [11]
11 Affinity Capture-Western [38]
12 Affinity Capture-Western [35]
13 Affinity Capture-Western [6]
14 Affinity Capture-Western [7]
15 Affinity Capture-Western [8]
16 Affinity Capture-Western [9]
17 Affinity Capture-Western [39]
18 Affinity Capture-Western [40]
19 Affinity Capture-Western [41]
20 Affinity Capture-Western [42]
Interacting Target Name Histone deacetylase 9 (HDAC9) Patented-recorded Target Interacting Protein Info
UniProt ID
HDAC9_HUMAN 
Synonyms MITR; MEF2-interacting transcription repressor MITR; KIAA0744; Histone deacetylase-related protein; Histone deacetylase 7B; HDRP; HDAC7B; HDAC7; HD9; HD7b
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [43]
2 Reconstituted Complex [44]
Cell cycle related proteins [+] 1 Cell cycle related proteins +
Interacting Target Name G1/S-specific cyclin-D1 (CCND1) Clinical trial Target Interacting Protein Info
UniProt ID
CCND1_HUMAN 
Synonyms PRAD1 oncogene; PRAD1; Cyclin D1; BCL-1 oncogene; BCL-1; BCL1; B-cell lymphoma 1 protein
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [45]
2 Co-localization [46]
Cell division cycle proteins [+] 1 Cell division cycle proteins +
Interacting Protein Name Retinoblastoma-associated protein (RB1) Interacting Protein Interacting Protein Info
UniProt ID
RB_HUMAN 
Synonyms OSRC; PPP1R130; RB; p105.Rb; pRb; pp110
Evidence Score (E-score) 12 Experimental Evidences +
1 Affinity Capture-MS [4]
2 Affinity Capture-Western [47]
3 Affinity Capture-Western [48]
4 Affinity Capture-Western [49]
5 Affinity Capture-Western [50]
6 Affinity Capture-Western [51]
7 Affinity Capture-Western [52]
8 Affinity Capture-Western [53]
9 Affinity Capture-Western [54]
10 Affinity Capture-Western [55]
11 Reconstituted Complex [56]
12 Reconstituted Complex [50]
Isomerases [+] 2 Isomerases +
Interacting Target Name DNA topoisomerase II alpha (TOP2A) Clinical trial Target Interacting Protein Info
UniProt ID
TOP2A_HUMAN 
Synonyms TOP2; DNA topoisomerase II, alpha isozyme; DNA topoisomerase 2-alpha; DNA topoisomerase 2alpha
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [57]
2 Affinity Capture-Western [58]
3 Reconstituted Complex [58]
Interacting Target Name Mitochondrial matrix protein P1 (HSPD1) Clinical trial Target Interacting Protein Info
UniProt ID
CH60_HUMAN 
Synonyms P60 lymphocyte protein; HuCHA60; HSP-60; Hsp60; Heat shock protein 60; CPN60; Chaperonin 60; 60 kDa heat shock protein, mitochondrial; 60 kDa chaperonin
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [2]
2 Affinity Capture-Western [59]
Kinases [+] 2 Kinases +
Interacting Target Name Casein kinase II alpha (CSNK2A1) Clinical trial Target Interacting Protein Info
UniProt ID
CSK21_HUMAN 
Synonyms Protein kinase CK2; CK2A1; CK II alpha; CK II; Casein kinase II subunit alpha
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [25]
2 Biochemical Activity [60]
Interacting Protein Name DDB1- and CUL4-associated factor 1 (DCAF1) Interacting Protein Interacting Protein Info
UniProt ID
DCAF1_HUMAN 
Synonyms DCAF1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [61]
2 Reconstituted Complex [62]
Lyases [+] 1 Lyases +
Interacting Protein Name Chromodomain Y-like protein (CDYL) Interacting Protein Interacting Protein Info
UniProt ID
CDYL_HUMAN 
Synonyms CDYL1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [2]
2 Affinity Capture-MS [4]
3 Affinity Capture-Western [63]
Nuclear hormone receptors [+] 4 Nuclear hormone receptors +
Interacting Target Name Estrogen receptor (ESR) Successful Target Interacting Protein Info
UniProt ID
ESR1_HUMAN 
Synonyms Oestrogen receptor alpha; Oestrogen receptor; Nuclear receptor subfamily 3 group A member 1; NR3A1; Estrogen receptor alpha; Estradiol receptor; ESR; ER-alpha; ERalpha; ER
Evidence Score (E-score) 6 Experimental Evidences +
1 Affinity Capture-MS [64]
2 Affinity Capture-Western [65]
3 Affinity Capture-Western [66]
4 Affinity Capture-Western [67]
5 Co-localization [68]
6 Reconstituted Complex [65]
Interacting Target Name Glucocorticoid receptor (NR3C1) Successful Target Interacting Protein Info
UniProt ID
GCR_HUMAN 
Synonyms Nuclear receptor subfamily 3 group C member 1; GRL; GR; Glucocorticoid receptor; Alpha-A
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [69]
2 Co-fractionation [22]
3 Fluorescence Resonance Energy Transfer [70]
4 Reconstituted Complex [70]
Interacting Target Name Androgen receptor (AR) Successful Target Interacting Protein Info
UniProt ID
ANDR_HUMAN 
Synonyms Testosterone receptor; Nuclear receptor subfamily 3 group C member 4; NR3C4; Dihydrotestosterone receptor; DHTR; Androgen receptor
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [71]
2 Yeast two hybrid [72]
Interacting Target Name Orphan nuclear receptor SHP (NR0B2) Literature-reported Target Interacting Protein Info
UniProt ID
NR0B2_HUMAN 
Synonyms Small heterodimer partner; SHP; Short heterodimer partner; Nuclear receptor subfamily 0 group B member 2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [73]
2 Reconstituted Complex [73]
One-carbon transferases [+] 5 One-carbon transferases +
Interacting Target Name DNA [cytosine-5]-methyltransferase 1 (DNMT1) Clinical trial Target Interacting Protein Info
UniProt ID
DNMT1_HUMAN 
Synonyms MCMT; M.HsaI; Dnmt1; DNMT; DNA MTase HsaI; DNA methyltransferase HsaI; DNA (cytosine-5)-methyltransferase 1; DNA (cytosine5)methyltransferase 1; CXXC-type zinc finger protein 9; CXXCtype zinc finger protein 9; CXXC9; AIM
Evidence Score (E-score) 8 Experimental Evidences +
1 Affinity Capture-Western [74]
2 Affinity Capture-Western [75]
3 Affinity Capture-Western [11]
4 Affinity Capture-Western [76]
5 Affinity Capture-Western [77]
6 Co-fractionation [78]
7 Co-localization [79]
8 Reconstituted Complex [16]
Interacting Target Name DNA [cytosine-5]-methyltransferase 3B (DNMT3B) Clinical trial Target Interacting Protein Info
UniProt ID
DNM3B_HUMAN 
Synonyms M.HsaIIIB; Dnmt3b; DNA MTase HsaIIIB; DNA methyltransferase HsaIIIB; DNA methyltransferase 3B; DNA (cytosine-5)-methyltransferase 3B
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [80]
2 Co-purification [81]
3 Reconstituted Complex [80]
Interacting Target Name Enhancer of zeste homolog 2 (EZH2) Successful Target Interacting Protein Info
UniProt ID
EZH2_HUMAN 
Synonyms Lysine N-methyltransferase 6; Lysine Nmethyltransferase 6; KMT6; Histone-lysine N-methyltransferase EZH2; Histonelysine Nmethyltransferase EZH2; EZH2 Y641N mutations; EZH2 Y641F mutations; ENX-1; ENX1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [82]
2 Co-fractionation [83]
Interacting Target Name DNA [cytosine-5]-methyltransferase 3A (DNMT3A) Patented-recorded Target Interacting Protein Info
UniProt ID
DNM3A_HUMAN 
Synonyms M.HsaIIIA; Dnmt3a; DNA MTase HsaIIIA; DNA methyltransferase HsaIIIA; DNA (cytosine-5)-methyltransferase 3A
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [84]
2 Reconstituted Complex [84]
Interacting Target Name Mixed-lineage leukemia protein (MLL) Literature-reported Target Interacting Protein Info
UniProt ID
KMT2A_HUMAN 
Synonyms Zinc finger protein HRX; Trithorax-like protein; Trithoraxlike protein; p320; p180; Myeloid/lymphoid or mixed-lineage leukemia protein 1; Myeloid/lymphoid or mixed-lineage leukemia; MLL1; MLL cleavage product C180; Lysine N-methyltransferase 2A; Lysine Nmethyltransferase 2A; HTRX; HRX; Histonelysine Nmethyltransferase MLL; Histone-lysine N-methyltransferase 2A; CXXC-type zinc finger protein 7; CXXCtype zinc finger protein 7; CXXC7; ALL-1; ALL1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [85]
2 Reconstituted Complex [85]
Oxidoreductases [+] 3 Oxidoreductases +
Interacting Target Name Lysine-specific histone demethylase 1 (LSD) Clinical trial Target Interacting Protein Info
UniProt ID
KDM1A_HUMAN 
Synonyms Lysine-specific histone demethylase 1A; Lysinespecific histone demethylase 1A; LSD1; KIAA0601; KDM1; Flavin-containing amine oxidase domain-containing protein 2; Flavincontaining amine oxidase domaincontaining protein 2; BRAF35-HDAC complex protein BHC110; BRAF35HDAC complex protein BHC110; AOF2
Evidence Score (E-score) 14 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [5]
6 Affinity Capture-MS [8]
7 Affinity Capture-Western [86]
8 Affinity Capture-Western [11]
9 Affinity Capture-Western [8]
10 Affinity Capture-Western [29]
11 Affinity Capture-Western [87]
12 Affinity Capture-Western [88]
13 Co-fractionation [83]
14 Co-purification [89]
Interacting Target Name Lysine-specific demethylase 5B (KDM5B) Literature-reported Target Interacting Protein Info
UniProt ID
KDM5B_HUMAN 
Synonyms Retinoblastoma-binding protein 2 homolog 1; Retinoblastomabinding protein 2 homolog 1; RBP2-H1; RBP2H1; RBBP2H1; PLU-1; PLU1; Lysinespecific demethylase 5B; Jumonji/ARID domain-containing protein 1B; Jumonji/ARID domaincontaining protein 1B; JARID1B; Histone demethylase JARID1B; CT31; Cancer/testis antigen 31
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [90]
2 Affinity Capture-Western [91]
3 Reconstituted Complex [90]
Interacting Protein Name C-terminal-binding protein 1 (CTBP1) Interacting Protein Interacting Protein Info
UniProt ID
CTBP1_HUMAN 
Synonyms BARS
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [4]
2 Affinity Capture-Western [92]
3 Reconstituted Complex [93]
Pore-forming toxins [+] 1 Pore-forming toxins +
Interacting Target Name Cellular tumor antigen p53 (TP53) Clinical trial Target Interacting Protein Info
UniProt ID
P53_HUMAN 
Synonyms Tumor suppressor p53; Phosphoprotein p53; P53; Antigen NY-CO-13
Evidence Score (E-score) 9 Experimental Evidences +
1 Affinity Capture-Western [94]
2 Affinity Capture-Western [95]
3 Affinity Capture-Western [96]
4 Affinity Capture-Western [97]
5 Biochemical Activity [98]
6 Biochemical Activity [99]
7 Biochemical Activity [100]
8 Co-localization [97]
9 Reconstituted Complex [98]
Transcription regulators [+] 29 Transcription regulators +
Interacting Target Name Metastasis associated gene-1 (MTA1) Literature-reported Target Interacting Protein Info
UniProt ID
MTA1_HUMAN 
Synonyms Metastasis-associated protein MTA1; Metastasisassociated protein MTA1
Evidence Score (E-score) 13 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [5]
6 Affinity Capture-MS [6]
7 Affinity Capture-MS [7]
8 Affinity Capture-Western [6]
9 Affinity Capture-Western [11]
10 Co-fractionation [83]
11 Co-fractionation [33]
12 Co-localization [68]
13 Reconstituted Complex [101]
Interacting Protein Name Methyl-CpG-binding domain protein 2 (MBD2) Interacting Protein Interacting Protein Info
UniProt ID
MBD2_HUMAN 
Synonyms DMTase; NY.CO.41
Evidence Score (E-score) 9 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [8]
6 Affinity Capture-MS [31]
7 Affinity Capture-Western [31]
8 Affinity Capture-Western [8]
9 Co-purification [34]
Interacting Protein Name Methyl-CpG-binding domain protein 3 (MBD3) Interacting Protein Interacting Protein Info
UniProt ID
MBD3_HUMAN 
Evidence Score (E-score) 9 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [8]
6 Affinity Capture-Western [11]
7 Affinity Capture-Western [102]
8 Co-fractionation [33]
9 Co-purification [34]
Interacting Protein Name REST corepressor 1 (RCOR1) Interacting Protein Interacting Protein Info
UniProt ID
RCOR1_HUMAN 
Synonyms COREST; RCOR
Evidence Score (E-score) 9 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [8]
6 Affinity Capture-Western [103]
7 Affinity Capture-Western [26]
8 Affinity Capture-Western [8]
9 Affinity Capture-Western [29]
Interacting Protein Name Transcription factor p65 (RELA) Interacting Protein Interacting Protein Info
UniProt ID
TF65_HUMAN 
Synonyms NFKB3; p65
Evidence Score (E-score) 7 Experimental Evidences +
1 Affinity Capture-Western [104]
2 Affinity Capture-Western [105]
3 Affinity Capture-Western [106]
4 Affinity Capture-Western [107]
5 Affinity Capture-Western [108]
6 Reconstituted Complex [104]
7 Reconstituted Complex [42]
Interacting Protein Name Zinc finger and BTB domain-containing protein 16 (ZBTB16) Interacting Protein Interacting Protein Info
UniProt ID
ZBT16_HUMAN 
Synonyms PLZF; ZNF145
Evidence Score (E-score) 7 Experimental Evidences +
1 Affinity Capture-Western [109]
2 Affinity Capture-Western [110]
3 Affinity Capture-Western [111]
4 Reconstituted Complex [109]
5 Reconstituted Complex [112]
6 Reconstituted Complex [113]
7 Reconstituted Complex [114]
Interacting Target Name Hypoxia-inducible factor 1 alpha (HIF-1A) Clinical trial Target Interacting Protein Info
UniProt ID
HIF1A_HUMAN 
Synonyms Transcription factor HIF-1; PASD8; PAS domain-containing protein 8; MOP1; Member of PAS protein 1; Hypoxia-inducible transcription factor (HIF)-1; Hypoxia-inducible factor 1-alpha; Hypoxia-inducible factor 1; Hypoxia inducible factor 1; HIF-1-alpha; HIF-1alpha; HIF1-alpha; HIF-1 alpha; HIF1 alpha; Class E basic helix-loop-helix protein 78; bHLHe78; Basic-helix-loop-helix-PAS protein MOP1; ARNT-interacting protein; ARNT interacting protein
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-Western [115]
2 Affinity Capture-Western [116]
3 Affinity Capture-Western [117]
4 Reconstituted Complex [115]
5 Reconstituted Complex [118]
Interacting Protein Name Breast cancer metastasis-suppressor 1 (BRMS1) Interacting Protein Interacting Protein Info
UniProt ID
BRMS1_HUMAN 
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Affinity Capture-Western [119]
5 Affinity Capture-Western [120]
Interacting Protein Name Mesoderm induction early response protein 1 (MIER1) Interacting Protein Interacting Protein Info
UniProt ID
MIER1_HUMAN 
Synonyms ER1; MI.ER1
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-Western [121]
Interacting Protein Name Transcriptional repressor p66-alpha (GATAD2A) Interacting Protein Interacting Protein Info
UniProt ID
P66A_HUMAN 
Synonyms p66alpha
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Co-fractionation [33]
5 Reconstituted Complex [122]
Interacting Target Name DNA-binding factor KBF1 (p105) Clinical trial Target Interacting Protein Info
UniProt ID
NFKB1_HUMAN 
Synonyms Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Nuclear factor of kappa light polypeptide gene enhancer in Bcells 1; Nuclear factor NFkappaB p50 subunit; Nuclear factor NF-kappa-B p105 subunit; Nuclear factor NFkappaB p105 subunit; EBP-1; EBP1; DNA-binding factor KBF1; DNAbinding factor KBF1
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [104]
2 Affinity Capture-Western [123]
3 Co-localization [124]
4 Reconstituted Complex [104]
Interacting Protein Name SMARCE1-related protein (HMG20B) Interacting Protein Interacting Protein Info
UniProt ID
HM20B_HUMAN 
Synonyms BRAF25; BRAF35; HMGX2; HMGXB2; PP7706; SMARCE1r; SOXL; pp8857
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Affinity Capture-Western [89]
Interacting Protein Name Transcriptional repressor p66-beta (GATAD2B) Interacting Protein Interacting Protein Info
UniProt ID
P66B_HUMAN 
Synonyms MRD18; P66beta; p68
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Reconstituted Complex [122]
Interacting Protein Name PHD finger protein 21A (PHF21A) Interacting Protein Interacting Protein Info
UniProt ID
PF21A_HUMAN 
Synonyms BHC80
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Reconstituted Complex [125]
Interacting Protein Name REST corepressor 3 (RCOR3) Interacting Protein Interacting Protein Info
UniProt ID
RCOR3_HUMAN 
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
Interacting Protein Name Deoxynucleotidyltransferase terminal-interacting protein 1 (DNTTIP1) Interacting Protein Interacting Protein Info
UniProt ID
TDIF1_HUMAN 
Synonyms C20orf167; Tdif1; dJ447F3.4
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
Interacting Target Name Mothers against decapentaplegic homolog 7 (SMAD7) Clinical trial Target Interacting Protein Info
UniProt ID
SMAD7_HUMAN 
Synonyms Smad7; SMAD family member 7; SMAD 7; Mothers against DPP homolog 8; Mothers against decapentaplegic homolog 8; MAD homolog 8; hSMAD7
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [126]
2 Affinity Capture-Western [127]
3 Reconstituted Complex [126]
Interacting Target Name Transcription factor Sp1 (SP1) Clinical trial Target Interacting Protein Info
UniProt ID
SP1_HUMAN 
Synonyms TSFP1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [128]
2 Reconstituted Complex [129]
3 Yeast two hybrid [130]
Interacting Target Name Proto-oncogene c-Myc (MYC) Literature-reported Target Interacting Protein Info
UniProt ID
MYC_HUMAN 
Synonyms Transcription factor p64; Proto-oncogene c-Myc; Myc proto-oncogene protein; C-myc oncogene; C-myc; Class E basic helix-loop-helix protein 39; bHLHe39
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [2]
2 Affinity Capture-Western [131]
3 Reconstituted Complex [132]
Interacting Target Name Methyl cpg binding protein 2 (MECP2) Clinical trial Target Interacting Protein Info
UniProt ID
MECP2_HUMAN 
Synonyms Methyl-CpG-binding protein 2; MethylCpGbinding protein 2; MeCp-2 protein; MeCp2 protein; MeCp2
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [133]
2 Affinity Capture-Western [134]
3 Reconstituted Complex [135]
Interacting Protein Name B-cell lymphoma 6 protein (BCL6) Interacting Protein Interacting Protein Info
UniProt ID
BCL6_HUMAN 
Synonyms BCL5; BCL6A; LAZ3; ZBTB27; ZNF51
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [109]
2 Affinity Capture-Western [136]
3 Reconstituted Complex [137]
Interacting Protein Name High mobility group protein 20A (HMG20A) Interacting Protein Interacting Protein Info
UniProt ID
HM20A_HUMAN 
Synonyms HMGX1; HMGXB1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
Interacting Protein Name DNA-binding protein Ikaros (IKZF1) Interacting Protein Interacting Protein Info
UniProt ID
IKZF1_HUMAN 
Synonyms Hs.54452; IK1; IKAROS; LYF1; LyF.1; PPP1R92; PRO0758; ZNFN1A1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [4]
2 Affinity Capture-Western [138]
3 Affinity Capture-Western [139]
Interacting Protein Name Transcription factor PU.1 (SPI1) Interacting Protein Interacting Protein Info
UniProt ID
SPI1_HUMAN 
Synonyms OF; PU.1; SFPI1; SPI.1; SPI.A
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [140]
2 Affinity Capture-Western [134]
3 Reconstituted Complex [135]
Interacting Target Name Hexamethylene bis-acetamide-inducible protein 1 (HEXIM1) Literature-reported Target Interacting Protein Info
UniProt ID
HEXI1_HUMAN 
Synonyms Protein HEXIM1; Menage a quatre 1; MAQ1; Likely ortholog of mouse cardiac lineage protein 1; HIS1 protein; HIS1; Hexamethylene bis-acetamide-inducible protein 1; Estrogen down-regulated gene 1 protein; CLP1; Cardiac lineage protein 1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [141]
2 Affinity Capture-Western [117]
Interacting Target Name Mothers against decapentaplegic homolog 3 (SMAD3) Preclinical Target Interacting Protein Info
UniProt ID
SMAD3_HUMAN 
Synonyms TGF-beta response effector Smad3; Smad3; SMAD family member 3; SMAD 3; Mothers against DPP homolog 3; MMad3; MADH3; Mad3; MAD homolog 3; JV15-2; HSMAD3; HMAD-3
Evidence Score (E-score) 2 Experimental Evidences +
1 Reconstituted Complex [142]
2 Yeast two hybrid [143]
Interacting Protein Name B-cell lymphoma/leukemia 11B (BCL11B) Interacting Protein Interacting Protein Info
UniProt ID
BC11B_HUMAN 
Synonyms ATL1; ATL1.alpha; ATL1.beta; ATL1.delta; ATL1.gamma; CTIP.2; CTIP2; RIT1; ZNF856B; hRIT1.alpha
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [4]
2 Reconstituted Complex [144]
Interacting Protein Name Class E basic helix-loop-helix protein 41 (BHLHE41) Interacting Protein Interacting Protein Info
UniProt ID
BHE41_HUMAN 
Synonyms BHLHB3; DEC2; SHARP1; hDEC2
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-localization [145]
2 Reconstituted Complex [146]
Interacting Protein Name Transcriptional repressor protein YY1 (YY1) Interacting Protein Interacting Protein Info
UniProt ID
TYY1_HUMAN 
Synonyms DELTA; INO80S; NF.E1; UCRBP; YIN.YANG.1
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-localization [147]
2 Reconstituted Complex [148]
Ubiquitin related proteins [+] 1 Ubiquitin related proteins +
Interacting Target Name Ubiquitin-protein ligase E3 Mdm2 (MDM2) Clinical trial Target Interacting Protein Info
UniProt ID
MDM2_HUMAN 
Synonyms RING-type E3 ubiquitin transferase Mdm2; P53-binding protein Mdm2; Oncoprotein Mdm2; MDM2 protein; Hdm2; E3 ubiquitin-protein ligase Mdm2; Double minute 2 protein
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [149]
2 Co-localization [71]
3 Reconstituted Complex [149]
Other proteins [+] 23 Other proteins +
Interacting Protein Name Paired amphipathic helix protein Sin3a (SIN3A) Interacting Protein Interacting Protein Info
UniProt ID
SIN3A_HUMAN 
Evidence Score (E-score) 20 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [5]
6 Affinity Capture-MS [6]
7 Affinity Capture-MS [7]
8 Affinity Capture-MS [9]
9 Affinity Capture-Western [150]
10 Affinity Capture-Western [26]
11 Affinity Capture-Western [14]
12 Affinity Capture-Western [7]
13 Affinity Capture-Western [8]
14 Affinity Capture-Western [9]
15 Affinity Capture-Western [12]
16 Affinity Capture-Western [27]
17 Affinity Capture-Western [151]
18 Affinity Capture-Western [28]
19 Affinity Capture-Western [29]
20 Affinity Capture-Western [133]
Interacting Protein Name Metastasis-associated protein MTA2 (MTA2) Interacting Protein Interacting Protein Info
UniProt ID
MTA2_HUMAN 
Synonyms MTA1L1; PID
Evidence Score (E-score) 20 Experimental Evidences +
1 Affinity Capture-MS [152]
2 Affinity Capture-MS [1]
3 Affinity Capture-MS [2]
4 Affinity Capture-MS [3]
5 Affinity Capture-MS [4]
6 Affinity Capture-MS [5]
7 Affinity Capture-MS [7]
8 Affinity Capture-MS [8]
9 Affinity Capture-Western [153]
10 Affinity Capture-Western [26]
11 Affinity Capture-Western [11]
12 Affinity Capture-Western [8]
13 Affinity Capture-Western [9]
14 Affinity Capture-Western [29]
15 Affinity Capture-Western [150]
16 Affinity Capture-Western [32]
17 Co-fractionation [22]
18 Co-fractionation [83]
19 Co-fractionation [33]
20 Co-purification [34]
Interacting Protein Name Histone deacetylase complex subunit SAP30 (SAP30) Interacting Protein Interacting Protein Info
UniProt ID
SAP30_HUMAN 
Evidence Score (E-score) 12 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Affinity Capture-MS [6]
6 Affinity Capture-MS [9]
7 Affinity Capture-Western [154]
8 Affinity Capture-Western [14]
9 Affinity Capture-Western [9]
10 Affinity Capture-Western [28]
11 Co-purification [34]
12 Reconstituted Complex [155]
Interacting Protein Name Paired amphipathic helix protein Sin3b (SIN3B) Interacting Protein Interacting Protein Info
UniProt ID
SIN3B_HUMAN 
Evidence Score (E-score) 8 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Affinity Capture-MS [5]
5 Affinity Capture-Western [156]
6 Affinity Capture-Western [8]
7 Co-fractionation [83]
8 Co-purification [34]
Interacting Protein Name Promyelocytic leukemia protein (PML) Interacting Protein Interacting Protein Info
UniProt ID
PML_HUMAN 
Synonyms MYL; PP8675; RNF71; TRIM19
Evidence Score (E-score) 6 Experimental Evidences +
1 Affinity Capture-Western [157]
2 Affinity Capture-Western [158]
3 Affinity Capture-Western [159]
4 Reconstituted Complex [157]
5 Reconstituted Complex [158]
6 Yeast two hybrid [158]
Interacting Protein Name Inhibitor of growth protein 1 (ING1) Interacting Protein Interacting Protein Info
UniProt ID
ING1_HUMAN 
Synonyms p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [2]
2 Affinity Capture-MS [4]
3 Affinity Capture-Western [160]
4 Affinity Capture-Western [154]
5 Affinity Capture-Western [28]
Interacting Protein Name Metastasis-associated protein MTA3 (MTA3) Interacting Protein Interacting Protein Info
UniProt ID
MTA3_HUMAN 
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
5 Co-fractionation [83]
Interacting Protein Name Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) Interacting Protein Interacting Protein Info
UniProt ID
CDKA1_HUMAN 
Synonyms DOC1; DORC1; ST19; doc.1; p12DOC.1
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
Interacting Protein Name ELM2 and SANT domain-containing protein 1 (ELMSAN1) Interacting Protein Interacting Protein Info
UniProt ID
EMSA1_HUMAN 
Synonyms C14orf117; C14orf43; LSR68; c14_5541
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
Interacting Protein Name Genetic suppressor element 1 (GSE1) Interacting Protein Interacting Protein Info
UniProt ID
GSE1_HUMAN 
Synonyms KIAA0182
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-MS [4]
Interacting Protein Name Histone deacetylase complex subunit SAP130 (SAP130) Interacting Protein Interacting Protein Info
UniProt ID
SP130_HUMAN 
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [4]
4 Affinity Capture-MS [6]
Interacting Protein Name DNA damage-binding protein 1 (DDB1) Interacting Protein Interacting Protein Info
UniProt ID
DDB1_HUMAN 
Synonyms DDBA; UV.DDB1; XAP1; XPCE; XPE; XPE.BF
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [161]
2 Affinity Capture-Western [61]
3 Reconstituted Complex [162]
Interacting Protein Name T-complex protein 1 subunit alpha (TCP1) Interacting Protein Interacting Protein Info
UniProt ID
TCPA_HUMAN 
Synonyms CCT.alpha; CCT1; CCTa; D6S230E; TCP.1.alpha
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [5]
Interacting Target Name Poly [ADP-ribose] polymerase 1 (PARP1) Successful Target Interacting Protein Info
UniProt ID
PARP1_HUMAN 
Synonyms Protein poly-ADP-ribosyltransferase PARP1; PPOL; Poly[ADP-ribose] synthetase-1; Poly[ADP-ribose] synthase 1; Poly(ADP-ribose)polymerase-1; PARP-1; NAD(+)Poly [ADP-ribose] polymerase-1 ADP-ribosyltransferase-1; NAD(+) ADP-ribosyltransferase-1; NAD(+) ADP-ribosyltransferase 1; DNA ADP-ribosyltransferase PARP1; ARTD1; ADPRT 1; ADPRT; ADP-ribosyltransferase diphtheria toxin-like 1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [163]
2 Biochemical Activity [164]
Interacting Target Name Beta-catenin (CTNNB1) Successful Target Interacting Protein Info
UniProt ID
CTNB1_HUMAN 
Synonyms Wnt/beta-catenin signaling pathway; PRO2286; OK/SW-cl.35; CTNNB; Catenin beta-1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [165]
2 Affinity Capture-Western [166]
Interacting Target Name DNA [cytosine-5]-methyltransferase 3-like (DNMT3L) Patented-recorded Target Interacting Protein Info
UniProt ID
DNM3L_HUMAN 
Synonyms DNA (cytosine-5)-methyltransferase 3-like
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [167]
2 Reconstituted Complex [168]
Interacting Target Name von Hippel-Lindau disease tumor suppressor (VHL) Patented-recorded Target Interacting Protein Info
UniProt ID
VHL_HUMAN 
Synonyms pVHL; Protein G7
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [169]
2 Reconstituted Complex [118]
Interacting Target Name Maspin (SERPINB5) Literature-reported Target Interacting Protein Info
UniProt ID
SPB5_HUMAN 
Synonyms Serpin B5; Protease inhibitor 5; PI-5; PI5; Peptidase inhibitor 5
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [170]
2 Yeast two hybrid [171]
Interacting Target Name Vitamin D3 up-regulated protein 1 (VDUP1) Literature-reported Target Interacting Protein Info
UniProt ID
TXNIP_HUMAN 
Synonyms Vitamin D(3) up-regulating protein-1; Thioredoxin-interacting protein; Thioredoxin-binding protein 2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [172]
2 Reconstituted Complex [173]
Interacting Target Name Melanoma differentiation-associated protein 6 (CDKN1A) Literature-reported Target Interacting Protein Info
UniProt ID
CDN1A_HUMAN 
Synonyms WAF1; SDI1; PIC1; P21(WAF1); P21; Melanoma differentiation associated protein 6; MDA-6; MDA6; Cyclin-dependent kinase inhibitor 1; CIP1; CDK-interacting protein 1; CAP20
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-localization [174]
2 Reconstituted Complex [175]
Interacting Target Name Prohibitin (PHB) Literature-reported Target Interacting Protein Info
UniProt ID
PHB_HUMAN 
Synonyms PHB1; HEL-215; HEL-S-54e
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [176]
2 Reconstituted Complex [177]
Interacting Protein Name Inhibitor of growth protein 2 (ING2) Interacting Protein Interacting Protein Info
UniProt ID
ING2_HUMAN 
Synonyms ING1L; p33ING2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [4]
2 Affinity Capture-Western [154]
Interacting Protein Name T-complex protein 1 subunit theta (CCT8) Interacting Protein Interacting Protein Info
UniProt ID
TCPQ_HUMAN 
Synonyms C21orf112; Cctq; D21S246; PRED71
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [2]
2 Affinity Capture-MS [5]
References  Top
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