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| Protein General Information |
Top |
| Full Name |
C-terminal-binding protein 1 (CTBP1)
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| UniProt ID |
CTBP1_HUMAN
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| Gene Name |
CTBP1
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| Gene ID |
1487
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Histone deacetylase 1 (HDAC1) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
Histone deacetylase 2 (HDAC2) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF. J Biol Chem. 2000 Dec 15;275(50):39762-6.
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| REF 2 |
The hTERT and hTERC telomerase gene promoters are activated by the second exon of the adenoviral protein, E1A, identifying the transcriptional corepressor CtBP as a potential repressor of both genes. Neoplasia. 2005 Jun;7(6):614-22.
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