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| Protein General Information (TTD Target) |
Top |
| Full Name |
DNA (cytosine-5)-methyltransferase 3-like (DNMT3L)
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Patented-recorded
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Target Info
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| UniProt ID |
DNM3L_HUMAN
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| Gene Name |
DNMT3L
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| Gene ID |
29947
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Histone deacetylase 1 (HDAC1) |
Target Info
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PPI Info
|
[1] |
| Interacting Clinical trial Target(s) |
DNA [cytosine-5]-methyltransferase 3B (DNMT3B) |
Target Info
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PPI Info
|
[2] |
| Interacting Patented-recorded Target(s) |
DNA [cytosine-5]-methyltransferase 3A (DNMT3A) |
Target Info
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PPI Info
|
[3] |
| References |
Top |
| REF 1 |
Dnmt3L is a transcriptional repressor that recruits histone deacetylase. Nucleic Acids Res. 2002 Sep 1;30(17):3831-8.
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| REF 2 |
DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction. J Biol Chem. 2004 Jun 25;279(26):27816-23.
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| REF 3 |
Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development. 2002 Apr;129(8):1983-93.
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