Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T99402 | Target Info | |||
| Target Name | Metabotropic glutamate receptor 4 (mGluR4) | ||||
| Synonyms |
mGluR4; Group III metabotropic glutamate receptor 4; GPRC1D
Click to Show/Hide
|
||||
| Target Type | Literature-reported Target | ||||
| Gene Name | GRM4 | ||||
| Biochemical Class | GPCR glutamate | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 32 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
LY354740
Click to Show/Hide
|
Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
Eglumetad; Eglumegad; 176199-48-7; (1S,2S,5R,6S)-2-aminobicyclo[310]hexane-2,6-dicarboxylic acid; Eglumegad [INN]; UNII-ONU5A67T2S; LY-354740; LY 354740; ONU5A67T2S; CHEMBL8759; Eglumegad (INN); (1S,2S,5R,6S)-2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid; (1R,4S,5S,6S)-4-aminobicyclo[310]hexane-4,6-dicarboxylic acid; (1S,2S,5R,6S)-2-Amino-bicyclo[310]hexane-2,6-dicarboxylic acid; [3H]Eglumegad; LY366563; Eglumetad [USAN:INN]; (+)-2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid; 40F; PubChem18158; Eglumegad; Eglumegad [USAN]; Eglumegad hydrate; Eglumetad hydrate; LY 314582; LY 366563; LY314582; Eglumegad (USAN); LY-314582; LY-354740 monohydrate; LY-366563; Eglumetad (INN/USAN); (1R,4S,5S,6S)-4-aminobicyclo[310]hexane-4,6-dicarboxylic acid hydrate; (1S,2S,5R,6S)-2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid monohydrate; 2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid; 4-aminobicyclo[310]hexane-4,6-dicarboxylic acid; [3H]eglumegad
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
PCCG-4
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(2S,1'S,2'S,3 R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki = 50000 nM
|
[2] | |||
| Compound Name |
(1S,3R)-ACPD
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(1S,3R)-1-ACPD; trans-ACPD; (1S,3S)-ACPD; 1S,3R-ACPD
Click to Show/Hide
|
||||
| Activity |
Ki = 98000 nM
|
[1] | |||
| Compound Name |
CPCCOEt
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327783; 179067-99-3; AC1O3E8H; 7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxylate ethyl ester; SCHEMBL12648369; MolPort-003-940-874; CPCCOEt, > AKOS024456339; LP00300; NCGC00024948-02; KB-49121; AS-16761; L000202; SR-01000597466; SR-01000597466-1; BRD-A05729358-001-01-2; ethyl (7E)-7-hydroxyimino-1,7a-dihydrocyclopropa[b]chromene-1a-carboxylate
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
(2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL482080; (2s,4r)-4-(3-Methoxy-3-Oxopropyl) Glutamic Acid; (2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic Acid; ZINC40934342; BDBM50252048; (4R)-4-(3-methoxy-3-oxopropyl)-L-glutamic acid; (2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedioic acid
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
SIB-1757
Click to Show/Hide
|
Investigative | Compound Info | ||
| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
LY-389795
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL88999; LY389795; LY-389795; GTPL3349; BDBM50089897; LY 389795; (4S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid; 4-Amino-2-thia-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid(LY389795)
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
Ro64-5229
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ro 64-5229
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
[3H]quisqualate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Quisqualic acid; QUISQUALIC ACID; Quisqualate; L-Quisqualic acid; 52809-07-1; (+)-Quisqualic acid; UNII-8OC22C1B99; C5H7N3O5; CHEBI:8734; CHEMBL279956; 8OC22C1B99; (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid; 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine; 2jbk; 1,2,4-Oxadiazolidine-2-propanoic acid, alpha-amino-3,5-dioxo-, (S)-; (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID; 2or4; AC1ODZB5; (S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid; QUS; SR-01000075471; QUISQUALATE
Click to Show/Hide
|
||||
| Activity |
Ki = 112000 nM
|
[4] | |||
| Compound Name |
(1S,3S)-1-Aminocyclopentane-1,3-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
cis-ACPD; CHEMBL29726; Cis-1-aminocyclopentane-1,3-dicarboxylic acid; (+/-)-trans-ACPD; 1-amino-cis-cyclopentane-1,3-dicarboxylic acid; 1S, 3R-ACPD; (1S,3S)-ACPD; Tocris-0186; Tocris-0187; Tocris-0284; 1,3-Cyclopentanedicarboxylicacid, 1-amino-, (1S,3S)-; 1R,3R-ACPD; 1R,3S-ACPD; 1S,3S-ACPD; (+/-)-1-AMINOCYCLOPENTANE-cis-1,3-DICARBOXYLIC ACID; SCHEMBL481144; CTK0H2865; YFYNOWXBIBKGHB-FFWSUHOLSA-; ZINC1641373; BDBM50004863; MFCD00153759; AKOS006273106; NCGC00024487-01; NCGC00024488-01; NCGC00024488-02; B6219; 1-Aminocyclopentane-cis-1,3-dicarboxylic acid; M01251; A824378; SR-01000597676; 1-Amino-cyclopentane-1,3-dicarboxylic acid (APCD); SR-01000597676-1; (1S,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid; (1S,3S)-1-azanylcyclopentane-1,3-dicarboxylic acid; Q27458657; 1-Amino-cyclopentane-1,3-dicarboxylic acid(cis-(1S,3S)-ACPD)
Click to Show/Hide
|
||||
| Activity |
EC50 = 50000 nM
|
[5] | |||
| Compound Name |
L-Homocysteic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(2S)-2-Amino-4-sulfobutanoic acid; L-2-Amino-4-sulfobutyric acid; L-HOMOCYSTEATE; Homocysteic acid; (S)-2-amino-4-sulfobutanoic acid; UNII-YW13F86W9W; CHEMBL230951; YW13F86W9W; (2~{S})-2-azanyl-4-sulfo-butanoic acid; L-2-Amino-4-sulfobutyrate; SCHEMBL157695; (S)-2-amino-4-sulfobutyric acid; ZINC2567965; (2S)-2-amino-4-sulfobutyric acid; BDBM50220147; MFCD00066018; PDSP1_001269; PDSP2_001253; C16511; H-2740; Q15410991; UNII-HYA2G5T79L component VBOQYPQEPHKASR-VKHMYHEASA-N
Click to Show/Hide
|
||||
| Activity |
Ki = 53000 nM
|
[6] | |||
| Compound Name |
(2S)-2-Amino-4-[hydroxy-[hydroxy-(4-methylsulfonylphenyl)methyl]phosphoryl]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4094636; SCHEMBL8232961; BDBM50255293
Click to Show/Hide
|
||||
| Activity |
EC50 = 59000 nM
|
[7] | |||
| Compound Name |
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-ethyl-cyclopropanecarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL439775; BDBM50072172; (1S,2S,3S)-2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-ethylcyclopropane-1-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 60350 nM
|
[8] | |||
| Compound Name |
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-methyl-cyclopropanecarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97574; BDBM50072171; (1S,2S,3S)-2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-methylcyclopropane-1-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 62850 nM
|
[8] | |||
| Compound Name |
(1S,3S)-1-Amino-3-phosphonocyclopentanecarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL35111; 1-Amino-3-phosphono-cyclopentanecarboxylic acid; BDBM50021548
Click to Show/Hide
|
||||
| Activity |
EC50 = 86000 nM
|
[9] | |||
| Compound Name |
(3-Amino-3-methylbutyl)phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279838; SCHEMBL5063485; BDBM50089902; (3-Amino-3-methyl-butyl)-phosphonic acid(MAP4)
Click to Show/Hide
|
||||
| Activity |
Ki = 88000 nM
|
[1] | |||
| Compound Name |
(S)-2-Amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-5-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288491; BDBM50331746
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
(S)-2-Amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-1,2,3-triazol-5-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1289762; BDBM50331745
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-(2,6-Dichloro-phenyl)-7-ethyl-5-(2-methoxy-phenyl)-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid dimethylaminomethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89293; SCHEMBL13319998; BDBM50089892
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
4-Amino-2-thia-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL8839; LY-389795; SCHEMBL2450641; CTK1A0220; DTXSID40436647; BDBM50074750; (1beta,5beta)-4-Amino-2-thiabicyclo[3.1.0]hexane-4beta,6beta-dicarboxylic acid; (1R,4S,5S,6S)-4-Amino-2-thia-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid; 2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylicacid, 4-amino-, (1R,4S,5S,6S)-
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(S)-1-(2-Amino-2-carboxyethyl)-1H-1,2,3-triazole-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288410; BDBM50331744; ZINC64573062
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
3-[[[(3S)-3-Amino-3-carboxypropyl]-hydroxyphosphoryl]methyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4103332; SCHEMBL4084499; BDBM50255405
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyclopropylcyclopropane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1253501; BDBM50326794; (+/-)(1R,2S,3S)-3-[(S)-amino(carboxy)-methyl]-1,10-bi(cyclopropyl)-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
(4r)-4-[3-(Methylamino)-3-Oxopropyl]-L-Glutamic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL500042; BDBM50252051; ZINC40974521; (2S,4R)-4-(3-Methylamino-3-oxopropyl)glutamic acid; Q27453181; (2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pentanedioic acid
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S,4R)-4-(3-Amino-3-oxopropyl)glutamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL479804; BDBM50252050; ZINC40933343; (2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioic acid
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S,4R)-2-Amino-4-(3-(ethylamino)-3-oxopropyl)pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL479805; BDBM50252052
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
1-Amino-3-phosphono-3-cyclopentene-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL32972; 1-AMINO-3-PHOSPHONOCYCLOPENT-3-ENE-1-CARBOXYLIC ACID; CTK1A0696; DTXSID90437503; BDBM50089515; 1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid; 3-Cyclopentene-1-carboxylicacid, 1-amino-3-phosphono-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(S)-2-Amino-3-(1-((S)-1-carboxy-2-phenylethyl)-1H-1,2,3-triazol-4-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1289658; BDBM50331747
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
1-Amino-3-phosphono-2-cyclopentene-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL32651; CTK1A0695; DTXSID80438908; BDBM50089514; 1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid; 2-Cyclopentene-1-carboxylicacid, 1-amino-3-phosphono-; 1-AMINO-3-PHOSPHONOCYCLOPENT-2-ENE-1-CARBOXYLIC ACID
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyclohexylcyclopropane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1253502; BDBM50326793; (+/-)(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyclohexylcyclopropanecarboxylic acid
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
(S)-2-Amino-3-(1-(carboxymethyl)-1H-1,2,3-triazol-4-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288411; BDBM50331748
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL334160; SCHEMBL7140374; BDBM50138781; (1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-cyclopropanecarboxylic acid; (S)-Amino[(1S)-2beta-methyl-3alpha-carboxycyclopropane-1beta-yl]acetic acid
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[12] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 86 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid; (2R,4R)-APDC; (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid; 169209-63-6; 2R,4R-APDC; CHEMBL40086; CHEBI:40139; EN300-88063; 2R, 4R-APDC monohydrate; 52A; 4-amino-2,4-pyrrolidinedicarboxylic acid; AC1NSJRT; AC1Q4UAD; SCHEMBL158843; 2R, 4R-APDC; (2R,3R)-APDC; GTPL1392; CTK0E5090; DTXSID10415500; MolPort-003-982-102; BDBM50052398; ZINC32628523; SBB067830; MFCD16875409; AKOS015916056; AKOS015854214; RTC-065564; FCH3884669; NCGC00025040-02; LY314593; AJ-85443; SC-48823; TC-065564; B6634
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[1] | |||
| Compound Name |
1-benzyl-APDC
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60238; 171336-76-8; (2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid; GTPL1436; SCHEMBL8061968; CTK0A8043; DTXSID60573467; ZINC39952128; BDBM50071161; DB-064818; AJ-101168; FT-0772028; 4-amino-1-(phenylmethyl)pyrrolidine-2,4-dicarboxylic acid; (2R,4R)-4-amino-1-benzylpyrrolidine-2,4-dicarboxylic acid; (2R,4R)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid; (2R)-1-Benzyl-4-aminopyrrolidine-2beta,4alpha-dicarboxylic acid; 4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid(1-benzyl-APDC)
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(S)-(+)-CBPG
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CBPG; 3-[(S)-amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid; 180465-02-5; (S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-1-carboxylic acid; CHEMBL43412; S-(+)-CBPG; EN300-88066; (S)-(+)-CBPG; AC1NSJVN; AC1Q4UAL; SCHEMBL1308145; GTPL3421; (R)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-1-carboxylic acid; CTK7I3432; MolPort-044-812-180; MolPort-005-313-665; ZINC1485767; BDBM50052256; AKOS026740795; FCH4013584; AS-44366; OR312475; CS-0078773; KS-00000111; (s)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[1] | |||
| Compound Name |
LY307452
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
LY-307452; LY-307,452; LY 307452
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[1] | |||
| Compound Name |
(S)-4CPG
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(S)-4-carboxyphenylglycine
Click to Show/Hide
|
||||
| Activity |
Ki = 838000 nM
|
[4] | |||
| Compound Name |
ibotenate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ibotenic acid
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
AIDA
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UPF 523; UPF523; GNF-Pf-1401
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
MCCG
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MCCG-I
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
homo-AMPA
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL107768; homo-AMPA; HomoAMPA; AC1N6KQF; 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid; GTPL3359; SCHEMBL3731488; CTK8G0203; HMS3267O13; BDBM50052551; NCGC00024946-02; SR-01000597464; SR-01000597464-1; 2-amino-4-(5-methyl-3-oxo-1,2-oxazol-4-yl)butanoic acid; 2-Amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid; 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid; a-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolebutanoic acid; 2-amino-4-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)butanoic acid
Click to Show/Hide
|
||||
| Activity |
EC50 > 3000000 nM
|
[14] | |||
| Compound Name |
(S)-AMPA
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(S)-AMPA; 83643-88-3; (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; UNII-9280SC28GD; CHEMBL276815; 9280SC28GD; (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid; AMPA, L-; AMQ; glutamate-AMPA; 1ftm; Tocris-0254; Tocris-0169; Tocris-1074; S-AMPA; 1p1q; L-AMPA; Lopac-G-017; AC1L4JUQ; Biomol-NT_000216; (S)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; SCHEMBL667915; BPBio1_001304; CTK7I3476; BDBM17662; BDBM85214; UUDAMDVQRQNNHZ-YFKPBYRVSA-N; MolPort-003-940-001; MolPort-003-983-512; HMS3266E09
Click to Show/Hide
|
||||
| Activity |
EC50 > 3000000 nM
|
[14] | |||
| Compound Name |
(2S)-2-Amino-4-[hydroxy-[hydroxy-(4-morpholin-4-yl-3-nitrophenyl)methyl]phosphoryl]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4082270; SCHEMBL4103522; BDBM50255333
Click to Show/Hide
|
||||
| Activity |
EC50 = 241000 nM
|
[7] | |||
| Compound Name |
Iflwvshrwaivqf-sgihwfkdsa-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2115160; BDBM50407827; 2-[(1R,2R,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1R,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114112; BDBM50407822
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1S,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2115152; BDBM50407819
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1R,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2115157; BDBM50407830
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1S,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114105; BDBM50407826
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1R,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2115156; BDBM50407831
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1R,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2115159; BDBM50407820
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1R,2R,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114116; BDBM50407823
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
(2R,1S,2R,3S)-2-(2-Carboxy-3-phenylcyclopropyl)glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114110; PCCG-13; CTK7I3043; BDBM50407825; AKOS026748543; M02254; 2-[(1S,2R,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine; (2R,1'S,2'R3'S)-2-(2'-Carboxy-3'-phenulcyclopropyl)glycine; (1R,2S,3S)-2-[(R)-amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1S,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114106; BDBM50407828
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1S,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2115153; BDBM50407829
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1R,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114115; BDBM50407824
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1S,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2115151; BDBM50407821
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
2-[(1R,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114109; BDBM50407818
Click to Show/Hide
|
||||
| Activity |
Ki > 280000 nM
|
[2] | |||
| Compound Name |
(2R,4R)-4-Amino-1-methylpyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300330; SCHEMBL14278713; CTK1A0056; DTXSID10658238; BDBM50071164; ZINC29571185; (2R,4R)-4-Amino-1-methyl-pyrrolidine-2,4-dicarboxylic acid; 2,4-Pyrrolidinedicarboxylicacid, 4-amino-1-methyl-, (2R,4R)-
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL293434; SCHEMBL8973026; BDBM50071150; (2R,4R)-4-amino-1-[(2-phenylphenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2R,4R)-4-Amino-1-(3-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60008; SCHEMBL8973090; BDBM50071168; (2R,4R)-4-amino-1-[(3-chlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL61281; SCHEMBL8973223; BDBM50071155; (2R,4R)-4-amino-1-(naphthalen-2-ylmethyl)pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2S,4S)-2-Amino-4-(2,2-diphenylethyl)pentanedioic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40123; SCHEMBL187449; BDBM50069111; ZINC13797034; 2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid; (2S,4S)-2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[1] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1R,2S)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL231157; BDBM50220148; (2S,1''R,2''S)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
3-[(R)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97083; (R)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-1-carboxylic acid; SCHEMBL2266688; CTK7I3071; (R)-(?)-CBPG; BDBM50052255; ZINC12506682; AKOS026740796; CS-0078705; EN300-88067; 1-[(R)-amino(carboxy)methyl]bicyclo[1.1.1]pentane-3-carboxylic acid; 3-((R)-Amino-carboxy-methyl)-bicyclo[1.1.1]pentane-1-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[15] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1S,2R)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230852; BDBM50220150; (2R,1''S,2''R)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
(2R,4R)-4-Amino-1-(naphthalen-1-ylmethyl)pyrrolidine-2,4-dicarboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL302411; SCHEMBL8973459; BDBM50071159; (2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292553; SCHEMBL8972917; BDBM50071152; (2R,4R)-4-amino-1-(2-phenylethyl)pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1R,2S)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL389556; BDBM50220153; (2R,1''R,2''S)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1R,2R)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL389557; BDBM50220145; (2S,1''R,2''R)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1S,2R)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL389555; BDBM50220149; (2S,1''S,2''R)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
(2R,4R)-4-Amino-1-ethylpyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL59830; CTK1A0057; DTXSID80658240; BDBM50071156; ZINC26157741; (2R,4R)-4-Amino-1-ethyl-pyrrolidine-2,4-dicarboxylic acid; 2,4-Pyrrolidinedicarboxylicacid, 4-amino-1-ethyl-, (2R,4R)-
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1S,2S)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230949; BDBM50220151; (2R,1''S,2''S)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1R,2R)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230950; BDBM50220154; (2R,1''R,2''R)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1S,2S)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL389558; BDBM50220146; (2S,1''S,2''S)-2-(2''-sulfonocyclopropyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[6] | |||
| Compound Name |
(2R,4R)-4-Amino-1-(3,3-diphenyl-propyl)-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60302; BDBM50071166; (2R,4R)-4-amino-1-(3,3-diphenylpropyl)pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL304919; SCHEMBL8972526; BDBM50071151; (2R,4R)-4-amino-1-(2,2-diphenylethyl)pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2R,4R)-4-Amino-1-(2,6-dichloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60164; BDBM50071167; (2R,4R)-4-amino-1-[(2,6-dichlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418462; SCHEMBL8973329; BDBM50071165; (2R,4R)-4-amino-1-[(2-chlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[13] | |||
| Compound Name |
(2S,4S)-4-Methylglutamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(2S,4S)-2-amino-4-methylpentanedioic acid; CHEMBL41221; NSC-41355; (4S)-4-Methyl-L-glutamic Acid; NCIStruc1_000060; NCIStruc2_000006; SCHEMBL2263577; CTK5B3197; DTXSID70390561; ZINC896090; NCI41355; BDBM50031703; CCG-36834; NCGC00013482; AKOS006275456; NCGC00013482-02; NCGC00013482-03; NCGC00096596-01; NCGC00096596-02; (2S,4S)-2-Amino-4-methyl-pentanedioic acid; 2-Amino-4-methyl-pentanedioic acid(S-Me-Glu)
Click to Show/Hide
|
||||
| Activity |
Ki = 470000 nM
|
[1] | |||
| Compound Name |
(1S,3R)-1-Amino-3-(carboxymethyl)cyclopentane-1-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315032; SCHEMBL13319985; CTK0H1515; DTXSID10434110; BDBM50089911; AKOS006271974; (1s,3r)-1-amino-1-carboxycyclopentane-3-acetic acid; Cyclopentaneaceticacid, 3-amino-3-carboxy-, (1R,3S)-; 1-Amino-3-carboxymethyl-cyclopentanecarboxylic acid(1S,3R-homo-ACPD)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(2R)-3-(3''-Carboxybicyclo[1.1.1]pentyl)alanine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL450025; BDBM50254338
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[16] | |||
| Compound Name |
Benzylamino-(3-hydroxy-isoxazol-5-yl)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287785; BDBM50070576
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[17] | |||
| Compound Name |
(2S)-2-Amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-4-yl)-2-methylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL313713; BDBM50089891; 2-Amino-3-(3-hydroxy-5-oxo-[1,2,4]oxadiazol-4-yl)-2-methyl-propionic acid(S-MetQUIS)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(S)-2-Amino-4-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126608; Homoquisqualic acid; SCHEMBL13319913; BDBM50038038; 2-Amino-4-(3-hydroxy-5-oxo-5H-[1,2,4]oxadiazol-2-yl)-butyric acid(S-homoquisqualic acid)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(2S)-2-(3''-Carboxymethylbicyclo[1.1.1]pentyl)glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467234; BDBM50254389
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[16] | |||
| Compound Name |
2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL334842; SCHEMBL3261303; (2R)-2-amino-4-(4-oxo-1,2,5-thiadiazol-3-yl)butanoic Acid; BDBM50118479
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[18] | |||
| Compound Name |
(2R)-(3'-Phosphonomethylbicyclo[1.1.1]pentyl)glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467235; BDBM50254392; (2R)-(3''-Phosphonomethylbicyclo[1.1.1]pentyl)glycine
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[16] | |||
| Compound Name |
(2R)-2-(3''-Carboxymethylbicyclo[1.1.1]pentyl)glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL448885; BDBM50254390
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[16] | |||
| Compound Name |
trans-ACPD
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(1R,3S)-1-Aminocyclopentane-1,3-dicarboxylic acid; (1R,3S)-ACPD; CHEMBL36988; trans-(+/-)-ACPD monohydrate; (+/-)-trans-ACPD; (inverted exclamation markA)-trans-ACPD; 1-Amino-1,3-cyclopentanedicarboxylic acid; t-ACPD; 1-Amino-1,3-dicarboxycyclopentane; NSC 27386; (+/-)-1-AMINOCYCLOPENTANE-trans-1,3-DICARBOXYLIC ACID; 1,3-Cyclopentanedicarboxylic acid, 1-amino-, trans-; SCHEMBL4835874; CTK1H5156; 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1R,3S)-rel-; DTXSID201017343; BCP18261; ZINC2530680; BDBM50060136; MFCD11046039; AKOS006272258; CS-5853; HY-19434; AJ-190/40848563; (1R,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid; 1-Amino-cyclopentane-1,3-dicarboxylic acid(trans-ACPD); 1-Amino-cyclopentane-1,3-dicarboxylic acid(trans-(1R,3R)-ACPD); trans-(+/-)-1-Amino-1,3-cyclopentanedicarboxylic acid monohydrate
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[19] | |||
| Compound Name |
(S)-4-(Amino(carboxy)methyl)cubane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2021372; SCHEMBL7711939; BDBM50400856; CS-0091145
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(1R,2S)-2-Amino-2-carboxycyclopropane-1-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3347670; ZINC39058088
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[18] | |||
| Compound Name |
Ethylamino-(3-hydroxy-isoxazol-5-yl)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287737; BDBM50070577
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[17] | |||
| Compound Name |
(S)-2-Amino-5-phosphonopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
L-AP5; 5-phosphono-L-norvaline; CHEMBL71898; 2-Amino-5-phosphono-pentanoic acid; L(+)-2-Amino-5-phosphonopentanoic acid; Tocris-0107; SCHEMBL1662220; CTK7I3523; ZINC1854168; BDBM50017229; (s)-2-amino-5-phosphonovaleric acid; (S)-2-amino-5-phosphonopentanoicacid; AKOS024456367; (2S)-2-azaniumyl-5-phosphonopentanoate; (S)-2-Amino-5-phosphono-pentanoic acid; NCGC00024472-01; L-(+)-2-Amino-5-phosphonopentanoic acid; (2~{S})-2-azanyl-5-phosphono-pentanoic acid; SR-01000597696; SR-01000597696-1; UNII-39PJ29YY8Z component VOROEQBFPPIACJ-BYPYZUCNSA-N
Click to Show/Hide
|
||||
| Activity |
Ki = 1000000 nM
|
[1] | |||
| Compound Name |
(S)-Hibo
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL88184; NSC_194385; 2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid; BDBM85355; CTK5D3927; BDBM50089901; PDSP1_001437; PDSP2_001421; 5-Isoxazolepropanoicacid, a-amino-2,3-dihydro-3-oxo-; 2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid(S-HIBO)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(2R,4R)-1,4-Diamino-pyrrolidine-2,4-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297150; BDBM50078596; 4-Amino-2,4-dicarboxy-pyrrolidin-1-yl-ammonium(1-Amino-APDC)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(2S)-2-Amino-4-(4-oxo-1,2,5-thiadiazol-3-yl)butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL131922; BDBM50118480
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[18] | |||
| Compound Name |
(1R,2S)-1-Amino-2-[(4-oxo-1,2,5-thiadiazol-3-yl)methyl]cyclopropane-1-carboxylic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3347672
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[18] | |||
| Compound Name |
(RS)-3-Hydroxyphenylglycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Amino-2-(3-hydroxyphenyl)acetic acid; Amino(3-hydroxyphenyl)acetic acid; m-Hydroxyphenylglycine; CHEMBL88124; (S)-(3-Hydroxyphenyl)glycine; DL-2-(3-Hydroxyphenyl)glycine; Benzeneacetic acid, a-amino-3-hydroxy-; 2-(3-hydroxyphenyl)glycine; (RS)-3H-PG; SCHEMBL1512921; CTK4G7931; ALBB-016006; Amino(3-hydroxyphenyl)acetic acid #; BDBM50089914; AKOS000179898; AKOS017259239; Glycine, 2-(m-hydroxyphenyl)-, DL-; AB06901; MCULE-6517923716; 2-azaniumyl-2-(3-hydroxyphenyl)acetate; NCGC00024536-02; Amino-(3-hydroxy-phenyl)-acetic acid(S-HPG); W-7471; L001190; SR-01000597637; J-018571; SR-01000597637-1; benzeneacetic acid, alpha-amino-3-hydroxy-, hydrochloride
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
alpha-Methyl-4-carboxyphenylglycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(RS)-MCPG; alpha-Mcpg; 4-(1-amino-1-carboxyethyl)benzoic acid; (+/-)-alpha-Methyl-4-carboxyphenylglycine; (R,S)-MCPG; Benzeneacetic acid, alpha-amino-4-carboxy-alpha-methyl-; CHEMBL299683; (+/-)-alpha-Methyl-(4-carboxyphenyl)glycine; (rs)-alpha-methyl-4-carboxyphenylglycine; Benzeneacetic acid, a-amino-4-carboxy-a-methyl-; (+/-)-MCPG; alpha-Amino-4-carboxy-alpha-methylbenzeneacetic acid; ACMC-20cchr; 4-(1-AMINO-1-CARBOXY-ETHYL)-BENZOIC ACID; Lopac0_000747; SCHEMBL715285; (+-)-MCPG; (+/-)MCPG; CTK4C5052; KS-00001CLO; DTXSID80861398; HMS3262E16; BCP18268; Benzeneacetic acid, alpha-amino-4-carboxy-alpha-methyl-, (+-)-; Tox21_500747; BDBM50030627; MFCD00210205; (RS)-?-Methyl-4-carboxyphenylglycine; AKOS005066801; CCG-204832; CS-5708; LP00747; SDCCGSBI-0050725.P002; (y)-alpha-Methyl-4-carboxyphenylglycine; (?)-alpha-Methyl-4-carboxyphenylglycine; alpha-Methyl-2-(4-carboxyphenyl)glycine; NCGC00015676-03; NCGC00015676-04; NCGC00015676-05; NCGC00015676-06; NCGC00015676-09; NCGC00024542-02; NCGC00024542-03; NCGC00024542-04; NCGC00261432-01; BS-15439; (r,s)-alpha-methyl-4-carboxyphenylglycine; HY-100371; EU-0100747; ST50825577; Benzeneacetic acid,a-amino-4-carboxy-a-methyl-; M 4796; L000020; SR-01000075733; J-008240; SR-01000075733-1; 4-(1-Amino-1-carboxy-ethyl)-benzoic acid(S-M4CPG); Q27268302
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(S)-4-((1-Carboxyethyl)amino)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL58247; 4-[[(1S)-1-carboxyethyl]amino]benzoic acid; 4-{[(1S)-1-carboxyethyl]amino}benzoic acid; SCHEMBL350279; KS-00001CM5; BDBM50071162; ZINC52969665; 4-((S)-1-Carboxy-ethylamino)-benzoic acid; (2S)-2-[(4-Carboxyphenyl)amino]propanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[13] | |||
| Compound Name |
(1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46527; BDBM50064246; (1R,4R)-2beta-Aminobicyclo[2.1.1]hexane-2,5beta-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 1000000 nM
|
[5] | |||
| Compound Name |
(S)-3,5-Dihydroxyphenylglycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(S)-3,5-DHPG; S-DHPG; L-3,5-Dihydroxyphenylglycine; C8H9NO4; UNII-CF5G2G268A; CHEMBL39221; 3,5-Dihydroxy-L-phenylglycine; CF5G2G268A; (S)-3,5 DHPG; (S)-3,5-Dihydroxyphenylglycine hydrate; Benzeneacetic acid, alpha-amino-3,5-dihydroxy-, (alphaS)-; (2r)-Amino(3,5-Dihydroxyphenyl)Acetic Acid; (2S)-amino(3,5-dihydroxyphenyl)ethanoic acid; (S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid; (S)-3,5-dihydroxyphenylglycine zwitterion; Tocris-0342; Tocris-0805; Lopac-D-3689; C12026; 3,5-Dihydroxy-phenylglycine; Lopac0_000328; (2S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid; SCHEMBL12648471; (s)-3,5-dihydroxylphenylglycine; CTK8F0556; DTXSID20904031; HMS3261A17; HMS3266F22; HMS3411L21; HMS3675L21; ZINC968043; Dihydroxyphenylglycine, (S)-3,5-; Tox21_500328; BDBM50079183; MFCD11044457; AKOS006239507; amino(3,5-dihydroxyphenyl)acetic acid; CCG-204423; DB04228; LP00328; SDCCGSBI-0050316.P002; NCGC00015338-01; NCGC00015338-02; NCGC00024545-01; NCGC00024800-01; NCGC00024800-02; NCGC00024800-03; NCGC00024800-04; NCGC00024800-05; NCGC00024800-10; NCGC00261013-01; HY-12598; Amino-(3,5-dihydroxy-phenyl)-acetic acid; J516.528H; (2S)-amino(3,5-dihydroxyphenyl)acetic acid; B6459; CS-0012064; EU-0100328; (S)-Amino-(3,5-dihydroxy-phenyl)-acetic acid; D 3689; SR-01000075813; SR-01000597444; Amino-(3,5-dihydroxy-phenyl)-acetic acid(S-DHPG); J-009981; SR-01000075813-1; SR-01000597444-1; Q27095051; UNII-5YR2N37E6D component HOOWCUZPEFNHDT-ZETCQYMHSA-N
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42148; BDBM50064247; (1S,4S)-2beta-Aminobicyclo[2.1.1]hexane-2,5beta-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[5] | |||
| Compound Name |
alpha-Amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL280585; 2-amino-2-(5-methyl-3-oxo-1,2-oxazol-4-yl)acetic acid; Amaa acid; 2-Amino-3-hydroxy-5-methyl-4-isoxazoleacetic acid; SCHEMBL5290687; CTK5E3723; DTXSID20998293; BDBM50004852; alpha-amino-5-methyl-3-hydroxy-4-isoxazoleacetic acid; Amino-(3-hydroxy-5-methyl-isoxazol-4-yl)-acetic acid; Amino(3-hydroxy-5-methyl-1,2-oxazol-4-yl)acetic acid; 4-Isoxazoleacetic acid,a-amino-2,3-dihydro-5-methyl-3-oxo-; 2-Amino-2-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)acetic acid; Amino-(3-hydroxy-5-methyl-isoxazol-4-yl)-acetic acid (D-AMAA); 4-Isoxazoleacetic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-, (+-)-
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[17] | |||
| Compound Name |
(2S)-(3''-Phosphonomethylbicyclo[1.1.1]pentyl)glycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL445241; BDBM50254391
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[16] | |||
| Compound Name |
4-Carboxyphenylglycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(RS)-4-Carboxyphenylglycine; 4-[amino(carboxy)methyl]benzoic acid; 4-Carboxylphenylglycine; 4-CPG; 4-(Amino(carboxy)methyl)benzoic acid; (RS)-4CPG; (R)-4CPG; CHEMBL328984; (S)-4-Carboxyphenylglycine;4CPG; 4-(Amino-carboxy-methyl)-benzoic acid; 2-(4-Carboxyphenyl)glycine; Benzeneacetic acid, alpha-amino-4-carboxy-, (+-)-; SCHEMBL2266884; CTK2H8632; DTXSID70864035; BDBM50030629; MFCD00673852; NSC644612; 4-(amino-carboxy-methyl)benzoic acid; AKOS023158559; NSC-644612; (R,S)-4-Carboxy-3-hydroxyphenylglycine; NCI60_015099; FT-0694231; (+-)- alpha-amino-4-carboxy-Benzeneacetic acid; 4-(Amino-carboxy-methyl)-benzoic acid(S-4CPG); L001308; SR-01000597634; SR-01000597634-1
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
(3-Hydroxy-isoxazol-5-yl)-methylamino-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41352; BDBM50070575
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[17] | |||
| Compound Name |
(2S)-3-(3''-Carboxybicyclo[1.1.1]pentyl)alanine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL444718; BDBM50254337
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[16] | |||
| Compound Name |
(1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43857; BDBM50064245; (1R,4R)-2beta-Aminobicyclo[2.1.1]hexane-2,5alpha-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[5] | |||
| Compound Name |
2-Amino-2,3-methano-4-phosphonobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287703; (1R,2R)-1-amino-2-(phosphonomethyl)cyclopropane-1-carboxylic acid; (1R,2R)-1-amino-2-(phosphonomethyl)cyclopropanecarboxylic acid; 2-Ampba; DTXSID80928258; BDBM50089518; 1-amino-2-(phosphonomethyl)cyclopropane-1-carboxylic acid; (1R,2R)-1-amino-2-phosphonomethylcyclopropane-carboxylic acid; Cyclopropanecarboxylic acid, 1-amino-2-(phosphonomethyl)-, trans-(+-)-
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[21] | |||
| Compound Name |
4-Methylene-L-glutamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(2S)-2-amino-4-methylidenepentanedioic acid; CHEMBL38499; 4-Methylene-L-glutamate; 4-methylideneglutamic acid; L-Glutamic acid, 4-methylene-; gamma-Methylenglutaminsaure; 4-methylidene-L-glutamic acid; SCHEMBL497587; CTK8D4485; DTXSID70937430; ZINC895334; BDBM50089912; C00651; Q27104602
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(S)-2-Amino-3-(4-butyl-3-hydroxy-isoxazol-5-yl)-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315663; (R)-Bu-HIBO; (S)-4-Butylhomoibotenic acid; BDBM85348; BDBM50063485; 2-Amino-3-(4-butyl-3-hydroxy-isoxazol-5-yl)-propionic acid(S-Bu-HIBO)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(1S,2S)-1-Amino-2-(carboxymethyl)cyclopropane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CTK0H1302; CHEMBL3347671; DTXSID20472068; ZINC32629480; AKOS026740805; Cyclopropaneaceticacid, 2-amino-2-carboxy-, (1S,2S)-
Click to Show/Hide
|
||||
| Activity |
EC50 > 1000000 nM
|
[18] | |||
| Compound Name |
2-Amino-bicyclo[3.2.0]heptane-2,7-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL313394; SCHEMBL13319983; BDBM50089898; (2S,7S)-2-Amino-bicyclo[3.2.0]heptane-2,7-dicarboxylic acid
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
(RS)-4-Carboxy-3-hydroxyphenylglycine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-[amino(carboxy)methyl]-2-hydroxybenzoic acid; (RS)-4C3HPG; CHEMBL444589; 4-(Amino(carboxy)methyl)-2-hydroxybenzoic acid; Benzeneacetic acid, a-amino-4-carboxy-3-hydroxy-; (s)-4C3HPG; (+/-)-4-carboxy-3-hydroxyphenylglycine; 4-Chpgly; 4-[(S)-AMINO(CARBOXY)METHYL]-2-HYDROXYBENZOIC ACID; (RS)-4C3H-PG; 4-Carboxy-3-hydroxyphenylglycine; 4C3HPG; alpha-Amino-4-carboxy-3-hydroxybenzeneacetic acid; ACMC-20cesn; (+-)-alpha-Amino-4-carboxy-3-hydroxybenzeneacetic acid; Benzeneacetic acid, alpha-amino-4-carboxy-3-hydroxy-; SCHEMBL12648353; CTK4B8962; DTXSID60928397; Benzeneacetic acid, alpha-amino-4-carboxy-3-hydroxy-, (+-)-; HMS3266G05; HMS3266G09; HMS3411E05; HMS3675E05; BDBM50030628; 2-(4-Carboxy-3-hydroxyphenyl)glycine; AKOS024457427; 4-(Amino-carboxy-methyl)-2-hydroxy-benzoic acid; L000843; SR-01000597631; J-006476; SR-01000597631-1; BRD-A80383043-001-01-7; Q27165658; 4-(Amino-carboxy-methyl)-2-hydroxy-benzoic acid(S-4C3HPG)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315268; (S)-Homo-AMPA; NCGC00024946-01; Tocris-1026; SCHEMBL12506417; BDBM50060719; (s)-2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid; (S)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid; 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid(S-homo-AMPA)
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[1] | |||
| Compound Name |
L-2-Aminoadipic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(S)-2-aminohexanedioic acid; L-alpha-Aminoadipic acid; (2S)-2-aminohexanedioic acid; L-alpha-Aminoadipate; L-2-Aminoadipate; L-Homoglutamic acid; l-2-amino adipic acid; homoglutamic acid; (S)-2-Aminoadipic acid; UNII-88ZH74L7SR; hexanedioic acid, 2-amino-, (2S)-; h-2-aad-oh; l-a-aminoadipic acid; h-l-2-aad-oh; MFCD00002636; L-2-Aminohexanedioate; CHEMBL88804; 88ZH74L7SR; L-2-Aminoadipic acid, 98%; A-aminoadipic acid; Adipic acid, 2-amino-; alpha-Aminoadipate, L-; 2-Aminoadipic acid, L-; L-alpha-Aminoadipatic acid; Hexanedioic acid, 2-amino-, (S)-; l-a-aminohexanoic acid; (S)-Aminoadipic Acid; L-2-amino-adipic acid; aminoadipic acid, l-2-; l-alpha-amino-adipic acid; L -alpha-aminoadipic acid; (2S)-2-aminoadipic acid; l-alpha-aminohexanedioic acid; Lopac0_000091; SCHEMBL97323; KSC493I2B; (S)-2-amino-hexanedioic acid; (2S)-2-Amino-hexanedioic Acid; CTK3J3420; DTXSID801017096; HMS3260C04; KS-00000YV4; ZINC1532798; Tox21_500091; ANW-43725; BDBM50052553; AKOS015920301; CCG-204186; LP00091; SDCCGSBI-0050079.P002; L-2-Aminoadipic acid, >=98% (TLC); NCGC00093593-01; NCGC00093593-02; NCGC00093593-03; NCGC00093593-04; NCGC00260776-01; AS-13597; BR-25294; SC-10038; AB0013911; EU-0100091; A 7275; C00956; M-3010; 118A907; SR-01000075684; J-002657; SR-01000075684-1; Q27104392; Aad; (S)-2-Aminohexanedioic acid; L-Homoglutamic acid; 9EF7020B-8995-4D0E-BE44-34D8F18766DF; UNII-1K7B1OED4N component OYIFNHCXNCRBQI-BYPYZUCNSA-N
Click to Show/Hide
|
||||
| Activity |
Ki > 3000000 nM
|
[1] | |||
| Compound Name |
2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL324686; BDBM50052555
Click to Show/Hide
|
||||
| Activity |
EC50 > 3000000 nM
|
[14] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Ligands for glutamate receptors: design and therapeutic prospects. J Med Chem. 2000 Jul 13;43(14):2609-45. | ||||
| REF 2 | Synthesis and pharmacological characterization of all sixteen stereoisomers of 2-(2'-carboxy-3'-phenylcyclopropyl)glycine. Focus on (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a novel and selective group II metabotropic glutamate receptors antagonist. J Med Chem. 1996 May 24;39(11):2259-69. | ||||
| REF 3 | Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotr... J Med Chem. 2008 Jul 24;51(14):4093-103. | ||||
| REF 4 | Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity. J Med Chem. 2002 Jul 18;45(15):3171-83. | ||||
| REF 5 | Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist. J Med Chem. 1998 May 7;41(10):1641-50. | ||||
| REF 6 | Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisom... J Med Chem. 2007 Sep 20;50(19):4630-41. | ||||
| REF 7 | Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites. J Med Chem. 2018 Mar 8;61(5):1969-1989. | ||||
| REF 8 | 2,3'-disubstituted-2-(2'-carboxycyclopropyl)glycines as potent and selective antagonists of metabotropic glutamate receptors. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2849-54. | ||||
| REF 9 | Synthesis, molecular modeling and preliminary biological evaluation of 1-amino-3-phosphono-3-cyclopentene-1-carboxylic acid and 1-amino-3-phosphono-2-cyclopentene-1-carboxylic acid, two novel agonists of metabotropic glutamate receptors of group III. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1447-50. | ||||
| REF 10 | 1,2,3-triazolyl amino acids as AMPA receptor ligands. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7512-5. | ||||
| REF 11 | Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo[3.1.0] hexane-2,6-dicarboxylic acid (LY354740): identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptors. J Med Chem. 1999 Mar 25;42(6):1027-40. | ||||
| REF 12 | A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity. Bioorg Med Chem. 2010 Aug 15;18(16):6089-98. | ||||
| REF 13 | Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R,4R-4-aminopyrrolidine-2,4-dicarboxylic acid. Bioorg Med Chem Lett. 1998 Aug 4;8(15):1985-90. | ||||
| REF 14 | A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. J Med Chem. 1996 Aug 2;39(16):3188-94. | ||||
| REF 15 | (S)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine, a structurally new group I metabotropic glutamate receptor antagonist. J Med Chem. 1996 Jul 19;39(15):2874-6. | ||||
| REF 16 | Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based omega-acidic amino acids as glutamate receptors ligands. Bioorg Med Chem. 2009 Jan 1;17(1):242-50. | ||||
| REF 17 | Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid. Bioorg Med Chem Lett. 1998 Jun 16;8(12):1563-8. | ||||
| REF 18 | A highly selective agonist for the metabotropic glutamate receptor mGluR2. Medchemcomm. 2011;2:1120-4. | ||||
| REF 19 | Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes. J Med Chem. 1997 Sep 12;40(19):3119-29. | ||||
| REF 20 | 1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors. J Med Chem. 1995 Sep 15;38(19):3717-9. | ||||
| REF 21 | Synthesis and biological evaluation of 1-amino-2-phosphonomethylcyclopropanecarboxylic acids, new group III metabotropic glutamate receptor agonists. J Med Chem. 2007 Jul 26;50(15):3585-95. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.