Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03UIR
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| Former ID |
DNC013912
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| Drug Name |
(2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic Acid
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| Synonyms |
CHEMBL482080; (2s,4r)-4-(3-Methoxy-3-Oxopropyl) Glutamic Acid; (2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic Acid; ZINC40934342; BDBM50252048; (4R)-4-(3-methoxy-3-oxopropyl)-L-glutamic acid; (2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedioic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H15NO6
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| Canonical SMILES |
COC(=O)CCC(CC(C(=O)O)N)C(=O)O
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| InChI |
1S/C9H15NO6/c1-16-7(11)3-2-5(8(12)13)4-6(10)9(14)15/h5-6H,2-4,10H2,1H3,(H,12,13)(H,14,15)/t5-,6+/m1/s1
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| InChIKey |
IPTIKQIFOOZKAT-RITPCOANSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor ionotropic kainate 1 (GRIK1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Glutamatergic synapse | ||||
| Panther Pathway | Huntington disease | |||
| Ionotropic glutamate receptor pathway | ||||
| Metabotropic glutamate receptor group III pathway | ||||
| Metabotropic glutamate receptor group I pathway | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotr... J Med Chem. 2008 Jul 24;51(14):4093-103. | |||
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