Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04DKM
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| Former ID |
DIB018078
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| Drug Name |
(1S,3R)-ACPD
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| Synonyms |
(1S,3R)-1-ACPD; trans-ACPD; (1S,3S)-ACPD; 1S,3R-ACPD
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C7H11NO4
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| Canonical SMILES |
C1CC(CC1C(=O)O)(C(=O)O)N
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| InChI |
1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7+/m1/s1
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| InChIKey |
YFYNOWXBIBKGHB-FBCQKBJTSA-N
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| CAS Number |
CAS 111900-32-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7978513, 10233597, 14772609, 17404660, 24890591, 44434377, 47736593, 47959870, 48185094, 49959005, 50104329, 50104330, 53777203, 53837809, 57337829, 79091859, 87691008, 90341793, 91702841, 92303591, 103068735, 103078459, 103204760, 103942696, 104372878, 117541915, 121360860, 124749444, 129790327, 135060901, 135365907, 135649666, 137133099, 137783325, 140862489, 144220604, 162226686, 163302678, 163564051, 164823306, 164823307, 164848256, 184526316, 212343803, 226540646, 241181603, 252645287
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1365). | |||
| REF 2 | Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. J Neurochem. 2000 Dec;75(6):2590-601. | |||
| REF 3 | [3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells. Neuropharmacology. 1999 Oct;38(10):1519-29. | |||
| REF 4 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 294). | |||
| REF 5 | Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes. Naunyn Schmiedebergs Arch Pharmacol. 2000 Dec;362(6):546-54. | |||
| REF 6 | Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells. Brain Res Mol Brain Res. 1998 Jan;53(1-2):88-97. | |||
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