TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T99402	Metabotropic glutamate receptor 4	B0YI4S	(1S,3R)-1-Amino-3-(carboxymethyl)cyclopentane-1-carboxylic Acid	Investigative	10012681	C8H13NO4	187.19	C1C[C@](C[C@@H]1CC(=O)O)(C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B1U2ST	(2R,4R)-4-Amino-1-methylpyrrolidine-2,4-dicarboxylic acid	Investigative	44302818	C7H12N2O4	188.18	CN1C[C@](C[C@@H]1C(=O)O)(C(=O)O)N	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B1VT5M	Iflwvshrwaivqf-sgihwfkdsa-	Investigative	9991661	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@H]([C@@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B1X8RG	(2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302608	C19H20N2O4	340.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC=C2C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B29QMH	(2R)-3-(3''-Carboxybicyclo[1.1.1]pentyl)alanine	Investigative	44569827	C9H13NO4	199.2	C1C2(CC1(C2)C(=O)O)C[C@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B2MHI8	Benzylamino-(3-hydroxy-isoxazol-5-yl)-acetic acid	Investigative	15840277	C12H12N2O4	248.23	C1=CC=C(C=C1)CNC(C2=CC(=O)NO2)C(=O)O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B2Y1QJ	2-[(1R,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10752213	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@H]([C@H]2C(=O)O)[C@@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B3BD1R	2-[(1S,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10513894	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@@H]([C@@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B3HQT6	(2S)-2-Amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-4-yl)-2-methylpropanoic acid	Investigative	44322745	C6H9N3O5	203.15	C[C@](CN1C(=O)NOC1=O)(C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B45BXQ	(S)-2-Amino-4-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-butyric acid	Investigative	11820180	C6H9N3O5	203.15	C(CN1C(=O)NC(=O)O1)[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B48TJE	(2R,4R)-4-Amino-1-(3-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302605	C13H15ClN2O4	298.72	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC(=CC=C2)Cl)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B4NQ0Z	(2S,4S)-4-Methylglutamic acid	Investigative	3246152	C6H11NO4	161.16	C[C@@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 470000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B4SK1A	(2S)-2-(3''-Carboxymethylbicyclo[1.1.1]pentyl)glycine	Investigative	44569859	C10H15NO4	213.23	C1C2(CC1(C2)CC(=O)O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B4XAP2	2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyric acid	Investigative	9837114	C6H9N3O3S	203.22	C(C[C@H](C(=O)O)N)C1=NSNC1=O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B53OZS	(2R)-(3'-Phosphonomethylbicyclo[1.1.1]pentyl)glycine	Investigative	44569862	C9H16NO5P	249.2	C1C2(CC1(C2)CP(=O)(O)O)C[C@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B54BWE	(2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302609	C17H18N2O4	314.34	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC3=CC=CC=C3C=C2)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B5J7WM	2-[(1R,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10489914	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B5T6CU	(2S,4S)-2-Amino-4-(2,2-diphenylethyl)pentanedioic Acid	Investigative	10359073	C19H21NO4	327.4	C1=CC=C(C=C1)C(C[C@@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B5XW4D	(2R)-2-(3''-Carboxymethylbicyclo[1.1.1]pentyl)glycine	Investigative	44569860	C10H15NO4	213.23	C1C2(CC1(C2)CC(=O)O)C[C@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B6KD8I	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1R,2S)-	Investigative	17758443	C5H9NO5S	195.2	C1[C@@H]([C@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B7TMV2	3-[(R)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid	Investigative	10241509	C8H11NO4	185.18	C1C2(CC1(C2)C(=O)O)[C@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B7VM5K	trans-ACPD	Investigative	73537	C7H11NO4	173.17	C1C[C@@](C[C@H]1C(=O)O)(C(=O)O)N	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B8CUY3	2-[(1S,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	7157252	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@@H]([C@@H]2C(=O)O)[C@@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B8GS1W	2-[(1R,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10704895	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B8K6VC	(S)-4-(Amino(carboxy)methyl)cubane-1-carboxylic acid	Investigative	10198359	C11H11NO4	221.21	C12C3C4C1(C5C2C3(C45)C(=O)O)[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B8PEG2	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1S,2R)-	Investigative	17758444	C5H9NO5S	195.2	C1[C@H]([C@@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B91OPF	(1R,2S)-2-Amino-2-carboxycyclopropane-1-acetic acid	Investigative	45082292	C6H9NO4	159.14	C1[C@@H]([C@@]1(C(=O)O)N)CC(=O)O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B9BM4Y	Ethylamino-(3-hydroxy-isoxazol-5-yl)-acetic acid	Investigative	10103891	C7H10N2O4	186.17	CCNC(C1=CC(=O)NO1)C(=O)O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B9DR6Z	(S)-2-Amino-5-phosphonopentanoic acid	Investigative	1617110	C5H12NO5P	197.13	C(C[C@@H](C(=O)O)N)CP(=O)(O)O	Ki = 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	B9H5SN	(2S)-2-Amino-4-[hydroxy-[hydroxy-(4-morpholin-4-yl-3-nitrophenyl)methyl]phosphoryl]butanoic acid	Investigative	57765549	C15H22N3O8P	403.32	C1COCCN1C2=C(C=C(C=C2)C(O)P(=O)(CC[C@@H](C(=O)O)N)O)[N+](=O)[O-]	EC50 = 241000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BA89FL	(2R,4R)-4-Amino-1-(naphthalen-1-ylmethyl)pyrrolidine-2,4-dicarboxylic Acid	Investigative	10358265	C17H18N2O4	314.34	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC3=CC=CC=C32)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BA8XK5	2-[(1R,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10681240	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BB6KT7	(2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302930	C14H18N2O4	278.3	C1[C@@H](N(C[C@]1(C(=O)O)N)CCC2=CC=CC=C2)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BBF7L9	(S)-Hibo	Investigative	10012356	C6H8N2O4	172.14	C1=C(ONC1=O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BC96JQ	(2R,4R)-1,4-Diamino-pyrrolidine-2,4-dicarboxylic acid	Investigative	10330132	C6H11N3O4	189.17	C1[C@@H](N(C[C@]1(C(=O)O)N)N)C(=O)O	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BCD6I9	(2S)-2-Amino-4-(4-oxo-1,2,5-thiadiazol-3-yl)butanoic acid	Investigative	10465478	C6H9N3O3S	203.22	C(C[C@@H](C(=O)O)N)C1=NSNC1=O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BD93ST	2-[(1R,2R,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10489913	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@H]([C@@H]2C(=O)O)[C@@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BDX8L5	(2R,1S,2R,3S)-2-(2-Carboxy-3-phenylcyclopropyl)glycine	Investigative	10059959	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@@H]([C@@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BEM28T	(1R,2S)-1-Amino-2-[(4-oxo-1,2,5-thiadiazol-3-yl)methyl]cyclopropane-1-carboxylic acid;hydrochloride	Investigative	118718091	C7H10ClN3O3S	251.69	C1[C@H]([C@]1(C(=O)O)N)CC2=NSNC2=O.Cl	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BEW0U5	(RS)-3-Hydroxyphenylglycine	Investigative	1217	C8H9NO3	167.16	C1=CC(=CC(=C1)O)C(C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BGI1S7	alpha-Methyl-4-carboxyphenylglycine	Investigative	1222	C10H11NO4	209.2	CC(C1=CC=C(C=C1)C(=O)O)(C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BGQN61	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1R,2S)-	Investigative	17758445	C5H9NO5S	195.2	C1[C@@H]([C@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BH3E4M	(S)-4-((1-Carboxyethyl)amino)benzoic acid	Investigative	22884216	C10H11NO4	209.2	C[C@@H](C(=O)O)NC1=CC=C(C=C1)C(=O)O	IC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BI2F3N	2-[(1S,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10513896	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@@H]([C@H]2C(=O)O)[C@@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BI56LB	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1R,2R)-	Investigative	17758556	C5H9NO5S	195.2	C1[C@@H]([C@@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BIGT98	(1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid	Investigative	10775369	C8H11NO4	185.18	C1[C@@H]2C[C@]([C@H]1[C@@H]2C(=O)O)(C(=O)O)N	EC50 = 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BJ59AS	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1S,2R)-	Investigative	17758554	C5H9NO5S	195.2	C1[C@H]([C@@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BJ8Y6O	(S)-3,5-Dihydroxyphenylglycine	Investigative	443586	C8H9NO4	183.16	C1=C(C=C(C=C1O)O)[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BJNB38	(1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid	Investigative	10560963	C8H11NO4	185.18	C1[C@H]2C[C@]([C@@H]1[C@@H]2C(=O)O)(C(=O)O)N	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BK1E2B	alpha-Amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid	Investigative	173564	C6H8N2O4	172.14	CC1=C(C(=O)NO1)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BKM51O	(2S)-(3''-Phosphonomethylbicyclo[1.1.1]pentyl)glycine	Investigative	44569861	C9H16NO5P	249.2	C1C2(CC1(C2)CP(=O)(O)O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BKY9E8	4-Carboxyphenylglycine	Investigative	5115	C9H9NO4	195.17	C1=CC(=CC=C1C(C(=O)O)N)C(=O)O	IC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BNM4E5	2-[(1S,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10513895	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BO68UI	(3-Hydroxy-isoxazol-5-yl)-methylamino-acetic acid	Investigative	10374869	C6H8N2O4	172.14	CNC(C1=CC(=O)NO1)C(=O)O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BO9D5E	2-[(1R,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10752214	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@H]2C(=O)O)[C@@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BOCA73	(2R,4R)-4-Amino-1-ethylpyrrolidine-2,4-dicarboxylic acid	Investigative	44302837	C8H14N2O4	202.21	CCN1C[C@](C[C@@H]1C(=O)O)(C(=O)O)N	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BP9BL1	(2S)-3-(3''-Carboxybicyclo[1.1.1]pentyl)alanine	Investigative	44569826	C9H13NO4	199.2	C1C2(CC1(C2)C(=O)O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BP9I2D	(1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid	Investigative	10465017	C8H11NO4	185.18	C1[C@@H]2C[C@]([C@H]1[C@H]2C(=O)O)(C(=O)O)N	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BQIC40	2-Amino-2,3-methano-4-phosphonobutanoic acid	Investigative	125799	C5H10NO5P	195.11	C1[C@H]([C@]1(C(=O)O)N)CP(=O)(O)O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BR2O9H	4-Methylene-L-glutamic acid	Investigative	439282	C6H9NO4	159.14	C=C(C[C@@H](C(=O)O)N)C(=O)O	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BRSO72	(S)-2-Amino-3-(4-butyl-3-hydroxy-isoxazol-5-yl)-propionic acid	Investigative	10263168	C10H16N2O4	228.24	CCCCC1=C(ONC1=O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BSKL06	2-[(1S,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10704896	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BSWF59	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1S,2S)-	Investigative	17758555	C5H9NO5S	195.2	C1[C@H]([C@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BUBT35	(1S,2S)-1-Amino-2-(carboxymethyl)cyclopropane-1-carboxylic acid	Investigative	11768848	C6H9NO4	159.14	C1[C@H]([C@@]1(C(=O)O)N)CC(=O)O	EC50 > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BVM18G	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1R,2R)-	Investigative	17758449	C5H9NO5S	195.2	C1[C@@H]([C@@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BWC90O	2-Amino-bicyclo[3.2.0]heptane-2,7-dicarboxylic acid	Investigative	44322843	C9H13NO4	199.2	C1C[C@](C2C1C[C@@H]2C(=O)O)(C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BX3R5D	(RS)-4-Carboxy-3-hydroxyphenylglycine	Investigative	1297	C9H9NO5	211.17	C1=CC(=C(C=C1C(C(=O)O)N)O)C(=O)O	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BY4U5X	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1S,2S)-	Investigative	17758450	C5H9NO5S	195.2	C1[C@H]([C@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BYE7U4	(2R,4R)-4-Amino-1-(3,3-diphenyl-propyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302855	C21H24N2O4	368.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CCC(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BYK29C	(2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302856	C20H22N2O4	354.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CC(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BYWE14	(2R,4R)-4-Amino-1-(2,6-dichloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302686	C13H14Cl2N2O4	333.16	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=C(C=CC=C2Cl)Cl)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BZ07DY	2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid	Investigative	6604795	C8H12N2O4	200.19	CC1=C(C(=O)NO1)CC[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BZ20RS	L-2-Aminoadipic acid	Investigative	92136	C6H11NO4	161.16	C(C[C@@H](C(=O)O)N)CC(=O)O	Ki > 3000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BZ5HB6	(2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302819	C13H15ClN2O4	298.72	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC=C2Cl)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BZ67QI	2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-pentanoic acid	Investigative	44338561	C9H14N2O4	214.22	CC1=C(C(=O)NO1)CCCC(C(=O)O)N	EC50 > 3000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	BZP84A	2-[(1R,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10198574	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@H]2C(=O)O)[C@@H](C(=O)O)N	Ki > 280000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D01YEN	ibotenate	Investigative	1233	C5H6N2O4	158.11	C1=C(ONC1=O)C(C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D04JKL	AIDA	Investigative	2071	C11H11NO4	221.21	C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N	Ki > 1000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0EK6P	(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate	Investigative	5310984	C6H10N2O4	174.15	C1[C@@H](NC[C@]1(C(=O)O)N)C(=O)O	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0L0YF	homo-AMPA	Investigative	4236420	C8H12N2O4	200.19	CC1=C(C(=O)NO1)CCC(C(=O)O)N	EC50 > 3000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0N0NJ	1-benzyl-APDC	Investigative	15508178	C13H16N2O4	264.28	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC=C2)C(=O)O	IC50 > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0OH2P	(S)-(+)-CBPG	Investigative	5311040	C8H11NO4	185.18	C1C2(CC1(C2)C(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0OV2V	LY307452	Investigative	6324634	C21H25NO4	355.4	C1=CC=C(C=C1)C(CCC[C@@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2	Ki > 300000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0P3XO	(S)-4CPG	Investigative	5311459	C9H9NO4	195.17	C1=CC(=CC=C1[C@@H](C(=O)O)N)C(=O)O	Ki = 838000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0T5SU	(S)-AMPA	Investigative	158397	C7H10N2O4	186.17	CC1=C(C(=O)NO1)C[C@@H](C(=O)O)N	EC50 > 3000000 nM	Non binder
T99402	Metabotropic glutamate receptor 4	D0YO8B	MCCG	Investigative	5311457	C7H11NO4	173.17	C[C@]([C@H]1C[C@@H]1C(=O)O)(C(=O)O)N	Ki > 1000000 nM	Non binder