Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T70977 | Target Info | |||
| Target Name | Glycogen synthase kinase-3 beta (GSK-3B) | ||||
| Synonyms |
Serine/threonine-protein kinase GSK3B; GSK-3 beta
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| Target Type | Clinical trial Target | ||||
| Gene Name | GSK3B | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 196 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Niclosamide
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|
Approved | Compound Info | ||
| Synonyms |
niclosamide; 50-65-7; Niclocide; 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide; Tredemine; Bayluscid; Phenasal; Yomesan; Fenasal; Dichlosale; Helmiantin; Sagimid; Iomezan; Devermine; Atenase; Vermitid; Radeverm; Mansonil; Iomesan; Devermin; Cestocid; Sulqui; Lintex; Nasemo; Mato; Fedal-Telmin; Bayer 73; Radewerm; Zestocarp; Bayer 2353; 2',5-Dichloro-4'-nitrosalicylanilide; Chemagro 2353; BAY 2353; Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-; 5-Chloro-2'-chloro-4'-nitrosalicylanilide; nicolsamide; HL 2447; Niclosamidum [I
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| Activity |
IC50 = 77500 nM
|
[1] | |||
| Compound Name |
Hesperidin
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Approved | Compound Info | ||
| Synonyms |
hesperidin; 520-26-3; Cirantin; Hesperidoside; Hesper bitabs; Hesperetin-rutinosid; Hesperidine; UNII-E750O06Y6O; CCRIS 3940; (S)-(-)-Hesperidin; EINECS 208-288-1; NSC 44184; BRN 0075140; Hesperidin, (2S)-; Hesperetin 7-rutinoside; MLS001304066; (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one; CHEBI:28775; USAF CF-3; Hesperidin, (S)-(-)-; Hesperitin-7-rhamnoglucoside; E750O06Y6O; C28H34O15; HESPERIDINE
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| Activity |
IC50 = 100000 nM
|
[2] | |||
| Compound Name |
R-roscovitine
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Phase 2 | Compound Info | ||
| Synonyms |
Seliciclib; roscovitine; 186692-46-6; R-Roscovitine; (R)-roscovitine; CYC202; CYC-202; CYC 202; 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine; UNII-0ES1C2KQ94; Roscovitine (Seliciclib,CYC202); NSC 701554; AL-39256; Roscovitine; CHEMBL14762; 0ES1C2KQ94; CHEBI:45307; NSC701554; NSC-701554; (2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]amino]butan-1-ol; (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol; (2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol; RRC; Rosco; M02443; BMK1-E12; CYC202, Seliciclib, R-roscovitine, Roscovitine; (2r)-2-{[6-(benzylamino)-9-isopropyl-9h-purin-2-yl]amino}-1-butanol; 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol; 2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-(R)-1-butanol; 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
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| Activity |
IC50 = 130000 nM
|
[3] | |||
| Compound Name |
omega-chloroacetophenone
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Investigative | Compound Info | ||
| Synonyms |
mace (lacrimator); tear gas; phenacyl chloride; chloromethyl phenyl ketone
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| Activity |
IC50 = 50000 nM
|
[4] | |||
| Compound Name |
PMID24900428C14
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Investigative | Compound Info | ||
| Synonyms |
GTPL8154; BDBM50400754
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| Activity |
IC50 = 53300 nM
|
[5] | |||
| Compound Name |
thiadiazolidinone (TDZD) deriv. 6
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Investigative | Compound Info | ||
| Synonyms |
Thiadiazolidinone (TDZD) deriv. 6; 4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione; RGS4 inhibitor 11b; CCG 203769; AC1O6Z6H; CHEMBL24773; GTPL8033; BDBM7779; SCHEMBL13517142; HY-U00431; 410074-60-1; CS-0035365; 2-ethyl-4-butyl-1,2,4-thiadiazolidine-3,5-dione
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| Activity |
IC50 = 70000 nM
|
[6] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-1,5,7-triazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL453402; BDBM50267041; 1-(3,4-Dimethoxyphenyl)-3,4-dihydro-5H-dipyrrolo [1,2-a:20,30-e]pyrazin-5-one
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Chembl4208804
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456521
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-[2-[2-(1H-Indol-3-yl)ethylamino]-2-oxoethyl]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3939142; BDBM50203547
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
3,6-Diamino-2-(3-chlorobenzoyl)-4-(2-iodophenyl)thieno[2,3-b]pyridine-5-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2313844; SCHEMBL1539816; BDBM50424225
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| Activity |
IC50 = 50000 nM
|
[10] | |||
| Compound Name |
Chembl4209197
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456508
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Chembl4212073
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456514
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(3r)-1-{2-[4-(4-Acetylphenyl)piperazin-1-Yl]-2-Oxoethyl}-N-(3-Chloro-4-Hydroxyphenyl)pyrrolidine-3-Carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356117; SCHEMBL7878839; BDBM50030881; Q27453793
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1949788; SCHEMBL12134179; BDBM50364832; CH-4932748
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
2-(Chloroacetyl)thiophene
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Investigative | Compound Info | ||
| Synonyms |
2-chloro-1-thiophen-2-ylethanone; 2-chloro-1-(thiophen-2-yl)ethanone; 2-chloro-1-(thiophen-2-yl)ethan-1-one; 2-Chloro-1-thien-2-ylethanone; Ethanone,2-chloro-1-(2-thienyl)-; 2-Chloro-1-thiophen-2-yl-ethanone; 2-chloro-1-(2-thienyl)ethanone; Ethanone, 2-chloro-1-(2-thienyl)-; 2-chloroacetylthiophene; 2-alpha-chloroacetylthiophene; Chloromethyl 2-thienyl ketone; SCHEMBL230036; omega-chloro-2-acetylthiophene; thien-2-yl chloromethyl ketone; 2-thienylcarbonylmethyl chloride; BDBM7858; CHEMBL359135; CTK4G3660; DTXSID80374074; ZINC2383794; MFCD01812507; SBB051673; 2-chloro-1-(2-thienyl)ethan-1-one; Chloromethyl Thienyl Ketone deriv. 6; 2-chloranyl-1-thiophen-2-yl-ethanone; 2-chloro-1-(thiophen-2- yl)ethanone; AKOS000159612; MCULE-4696336501; VT20070; 2-chloro-1-(thiphen-2-yl)-1-ethanone; NS-01258; DB-047629; FT-0608750; A820011; J-017604
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| Activity |
IC50 = 50000 nM
|
[13] | |||
| Compound Name |
[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3086065; SCHEMBL959662; BDBM50443366
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| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
Triazolo[1,5-a]pyrimidine 17
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL382607; SCHEMBL14367583; BDBM11455
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| Activity |
IC50 = 50000 nM
|
[15] | |||
| Compound Name |
2-Bromo-1-(4-bromophenyl)ethanone O-methyl oxime
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1801620; BDBM50347517
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| Activity |
IC50 = 50000 nM
|
[16] | |||
| Compound Name |
Chembl4203063
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456518
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1949789; SCHEMBL12134185; BDBM50364833; CH-4932750
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
3-(3,4-Dichlorophenyl)-5-oxa-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL478517; BDBM50267080; 1-(3,4-Dichlorophenyl)furo[2,3-e]pyrrolo [1,2-a]pyrazin-5(4H)-one
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-5-oxa-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL478704; BDBM50267081; 1-(3,4-dimethoxyphenyl)furo[2,3-e]pyrrolo[1,2-a]pyrazin-5(4H)-one
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
3-(3,4-Dimethoxy-phenyl)-furo[2,3-b]pyrrolizin-8-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL286423; BDBM50240447; 3-(3,4-dimethoxyphenyl)-8H-furo[2,3-b]pyrrolizin-8-one
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
3-(4-Chlorophenyl)-1,5,7-triazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL516901; BDBM50267040; 1-(4-Chlorophenyl)-3,4-dihydro-5H-dipyrrolo [1,2-a:20,30-e]pyrazin-5-one
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1081198; SCHEMBL5480112; BDBM50312153
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| Activity |
IC50 = 50000 nM
|
[17] | |||
| Compound Name |
1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL570666; SCHEMBL3644036; BDBM50303038; 1-(4-naphthalen-2-ylpyrimidin-2-yl)piperidin-4-amine
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| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
Chembl4213595
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456505
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| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
N-(6-Chloro-5-(pyridin-4-yl)-1H-indazol-3-yl)butyramide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1077233; SCHEMBL6477004; BDBM50313699; N-(6-chloro-5-pyridin-4-yl-1H-indazol-3-yl)butanamide; N-[6-chloro-5-(4-pyridyl)-1H-indazol-3-yl]butanamide
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| Activity |
IC50 = 50000 nM
|
[19] | |||
| Compound Name |
3-(3-(Benzyloxy)-4-methoxyphenyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL507162; BDBM50267108
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Chembl4215567
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456511
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| Activity |
IC50 = 50000 nM
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[8] | |||
| Compound Name |
3-(4-Chlorophenyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL476236; CTK2G8703; DTXSID00464128; BDBM50267107; Pyrrolo[2,3-b]pyrrolizin-8(1H)-one, 3-(4-chlorophenyl)-
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Pyrazolo[1,5-a]pyrimidine 9j
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL361231; SCHEMBL14427373; BDBM11437
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| Activity |
IC50 = 50000 nM
|
[20] | |||
| Compound Name |
Pyrazolo[1,5-a]pyrimidine 9g
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL180714; SCHEMBL14427437; BDBM11434
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| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
N-[2-[2-(1H-Indol-3-yl)ethylamino]-2-oxoethyl]-2-phenyl-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3912650; BDBM50203638
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
Pyrazolo[1,5-a]pyrimidine 9f
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL181293; SCHEMBL14427494; BDBM11433
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| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
4-Tert-Butyl-N-[2-Methyl-3-(6-{[4-(Morpholin-4-Ylcarbonyl)phenyl]amino}-7h-Purin-2-Yl)phenyl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3263640; BDBM50012060; Q27453164; 4-t-butyl-N-[2-methyl-3-(6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-7h-purin-2-yl)phenyl]benzamide; 4-tert-butyl-N-[2-methyl-3-[6-[4-(morpholine-4-carbonyl)anilino]-7H-purin-2-yl]phenyl]benzamide
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| Activity |
IC50 ~ 50000 nM
|
[21] | |||
| Compound Name |
Chembl4204332
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456516
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
Chembl4204473
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456525
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| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
1-(4-Methoxyphenyl)furo[2,3-e]pyrrolo [1,2-a]pyrazin-5(4H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL478516; BDBM50267079
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Chembl4211676
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456524
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Chembl4207131
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456522
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-[3-[3-Methyl-4-(3-methylphenyl)piperazin-1-yl]propyl]-3-pyridin-4-yl-1,2,4-oxadiazole-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL428252; BDBM50377192
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| Activity |
IC50 ~ 50000 nM
|
[22] | |||
| Compound Name |
1-(4-Methylphenyl)furo[2,3-e]pyrrolo[1,2-a] pyrazin-5(4H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL517669; BDBM50267078
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
1-(4-Bromophenyl)furo[2,3-e]pyrrolo[1,2-a] pyrazin-5(4H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL477954; BDBM50267076
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
1-(5-Acetyl-thiophen-2-yl)-2-chloro-ethanone
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Investigative | Compound Info | ||
| Synonyms |
Chloromethyl Thienyl Ketone deriv. 19; 1-(5-acetylthiophen-2-yl)-2-chloroethanone; 1-(5-ACETYL-2-THIENYL)-2-CHLORO-ETHANONE; BDBM7871; CHEMBL143525; Ethanone, 1-(5-acetyl-2-thienyl)-2-chloro- (9CI); SCHEMBL6795944; CTK1G7848; DTXSID60400148; ZINC224638; 1-(5-acetyl-2-thienyl)-2-chloro-1-ethanone; 2-chloro-1-(5-acetylthiophen-2-yl)ethan-1-one
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| Activity |
IC50 = 50000 nM
|
[13] | |||
| Compound Name |
Pyrazolo[1,5-a]pyrimidine 9i
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL181606; SCHEMBL14427440; BDBM11436
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
N-[2-[2-(1H-Indol-3-yl)ethylamino]-2-oxoethyl]-3-phenyl-1H-indole-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3909173; BDBM50203631
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
Chembl4216653
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Investigative | Compound Info | ||
| Synonyms |
BDBM50456520
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
1-(6-Amino-9H-purin-9-yl)ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1801630; 9-Acetyl-6-amino-9H-purine; SCHEMBL3630349; BDBM50347528
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
3-(3-Benzyloxy-4-methoxy-phenyl)-thieno[2,3-b]pyrrolizin-8-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL34267; SCHEMBL7003180; Thienopyrrolizine derivative, 4e; BDBM50240449; 3-(4-methoxy-3-phenylmethoxyphenyl)thieno[2,3-b]pyrrolizin-8-one; 3-(3-(benzyloxy)-4-methoxyphenyl)-8H-thieno[2,3-b]pyrrolizin-8-one
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
1-(4-Fluorophenyl)furo[2,3-e]pyrrolo[1,2-a] pyrazin-5(4H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL517818; BDBM50267077
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL35864; CTK1J2753; DTXSID60463516; BDBM50240446; Pyrrolo[2,3-b]pyrrolizin-8(1H)-one, 3-(3,4-dimethoxyphenyl)-; 3-(3,4-Dimethoxy-phenyl)-1H-1,3b-diaza-cyclopenta[a]pentalen-7-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Chembl4277269
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50469298
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[23] | |||
| Compound Name |
N-[6-(4-Hydroxyphenyl)-5-phenyl-1H-indazol-3-yl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1093745; SCHEMBL6477490; BDBM50313676; Q27457082; N-(6-(4-hydroxyphenyl)-5-phenyl-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[19] | |||
| Compound Name |
6-(2,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420911; BDBM50439463; 9-(9H-purin-6-yl)-2,9-diazaspiro[5.5]undecane; Q27451706; 15I
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[24] | |||
| Compound Name |
N-(5-Bromo-6-chloro-1H-indazol-3-yl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1089722; N-(5-bromo-6-chloro-1H-indazol-3-yl)butyramide; SCHEMBL1461482; BDBM50313700; ZINC49066403; butanamide,n-(5-bromo-6-chloro-1h-indazol-3-yl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[19] | |||
| Compound Name |
N-(5,6-Bis(4-hydroxyphenyl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1093390; SCHEMBL6479434; BDBM50313674; N-[5,6-bis(4-hydroxyphenyl)-1H-indazol-3-yl]butanamide; N-[5-(4-hydroxyphenyl)-6-(4-oxocyclohexa-2,5-dien-1-ylidene)-1,2-dihydroindazol-3-yl]butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[19] | |||
| Compound Name |
1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-(piperidin-1-ylmethyl)-N-(2-pyridin-4-ylethyl)triazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL113168; BDBM50130720
Click to Show/Hide
|
||||
| Activity |
EC50 = 57530 nM
|
[25] | |||
| Compound Name |
6-(3,5-Dimethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77002; SCHEMBL490489; 6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 16; BDBM7348; BDBM50474973; ZINC13492950; 6-(3,5-dimethoxyphenyl)[5h]pyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[26] | |||
| Compound Name |
2-[4-(2-Hydroxypropan-2-yl)anilino]-3H-benzimidazole-5-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2071614; BDBM50390500
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[27] | |||
| Compound Name |
2-(5-Methoxy-2-phenoxypyrimidin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2203558; BDBM50400746
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62500 nM
|
[5] | |||
| Compound Name |
2-[2-[2-(4-Fluorophenyl)ethyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2203560; BDBM50400744
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62500 nM
|
[5] | |||
| Compound Name |
5-(4-Chloro-5-methoxypyridin-2-yl)-N-(pyridin-4-ylmethyl)-1,3-oxazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957101; BDBM50026844
Click to Show/Hide
|
||||
| Activity |
IC50 = 63095.73 nM
|
[28] | |||
| Compound Name |
4-(Methyl(4-(5-methylthiophen-2-yl)pyrimidin-2-yl)amino)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL571525; SCHEMBL3518381; BDBM50303040; 4-[methyl-[4-(5-methylthiophen-2-yl)pyrimidin-2-yl]amino]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[18] | |||
| Compound Name |
2-Ethyl-5-imino-4-phenyl-1,2,4-thiadiazolidin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thiadiazolidinone (TDZD) deriv. 27; BDBM7800; CHEMBL284125; 1,2,4-Thiadiazolidin-3-one, 2-ethyl-5-imino-4-phenyl-; 2-Ethyl-3-oxo-4-phenyl-1,2,4-thiadiazolidin-5-imine; 5-Imino-4-phenyl-2-ethyl-1,2,4-thiadiazolidine-3-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[29] | |||
| Compound Name |
Chembl4285999
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50469296
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[23] | |||
| Compound Name |
2-(4-Bromophenyl)-5-[(2-nitrophenyl)methyl]-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334798; BDBM50428460
Click to Show/Hide
|
||||
| Activity |
IC50 = 67800 nM
|
[30] | |||
| Compound Name |
5-[[4-[[[5-(6-Methoxypyridin-3-yl)-1H-indazole-3-carbonyl]amino]methyl]piperidin-1-yl]methyl]furan-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3736035; SCHEMBL15223356
Click to Show/Hide
|
||||
| Activity |
IC50 = 70800 nM
|
[31] | |||
| Compound Name |
2-(4-Chlorophenyl)-5-[(2-nitrophenyl)methyl]-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334797; BDBM50428461
Click to Show/Hide
|
||||
| Activity |
IC50 = 71000 nM
|
[23] | |||
| Compound Name |
3-(1-(3-(1H-Imidazol-1-yl)propyl)-1H-indol-3-yl)-1-phenyl-4-(1H-pyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL560467; BDBM50295901
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 73340 nM
|
[32] | |||
| Compound Name |
2-Phenyl-5-(p-methoxybenzyl)-2,3-dihydro-1,5-benzothiazepine-4(5H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334791; BDBM50428467; J3.561.225D
Click to Show/Hide
|
||||
| Activity |
IC50 = 73700 nM
|
[30] | |||
| Compound Name |
5-[(2-Bromophenyl)methyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334789; BDBM50428469
Click to Show/Hide
|
||||
| Activity |
IC50 = 73900 nM
|
[30] | |||
| Compound Name |
2-Chloro-1-(3,4,5-tribromo-thiophen-2-yl)-ethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596364; BDBM50304443; 2-chloro-1-(3,4,5-tribromothiophen-2-yl)ethanol
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[13] | |||
| Compound Name |
2-Chloro-1-(3-methylthiophen-2-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Chloro-1-(3-methyl-2-thienyl)-ethanone; Chloromethyl Thienyl Ketone deriv. 11; BDBM7863; CHEMBL142327; Ethanone, 2-chloro-1-(3-methyl-2-thienyl)- (9CI); SCHEMBL6793998; CTK8J2762; ZINC13528249; AKOS010867520; 2-Chloro-1-(3-methyl-2-thienyl)ethanone; 2-Chloro-1-(3-methyl-thiophen-2-yl)-ethanone; 2-chloro-1-(3-methylthiophen-2-yl)ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[13] | |||
| Compound Name |
Thiadiazolidinone (TDZD) deriv. 26
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL25927; BDBM7799; ethyl-(2-ethyl-3-oxo-4-phenyl-1,2,4-thiadiazolidin-5-ylidene)urea; 3-ethyl-1-[(5Z)-2-ethyl-3-oxo-4-phenyl-1,2,4-thiadiazolidin-5-ylidene]urea
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[29] | |||
| Compound Name |
Chembl4280203
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50469303
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[23] | |||
| Compound Name |
5-[(2-Methylphenyl)methyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334790; BDBM50428468
Click to Show/Hide
|
||||
| Activity |
IC50 = 76100 nM
|
[30] | |||
| Compound Name |
5-Benzyl-2-(2-furyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2207938; BDBM50401957; CCG-31248; MCULE-8835723422; SR-01000907752; SR-01000907752-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 77200 nM
|
[33] | |||
| Compound Name |
Chembl4290490
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50469305
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[23] | |||
| Compound Name |
2-(4-Fluorophenyl)-5-[(2-nitrophenyl)methyl]-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334796; BDBM50428462
Click to Show/Hide
|
||||
| Activity |
IC50 = 81500 nM
|
[30] | |||
| Compound Name |
6-(3,4,5-Trimethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL312065; SCHEMBL490606; 6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 17; BDBM7349; BDBM50474967; 6-(3,4,5-trimethoxyphenyl)[5h]pyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[34] | |||
| Compound Name |
Chembl4279152
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50469294
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[23] | |||
| Compound Name |
N-(5-(Furan-3-yl)-6-(4-hydroxyphenyl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1077243; SCHEMBL6485147; BDBM50313673
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[19] | |||
| Compound Name |
2-Phenyl-1H-pyrrolo[2,3-b]quinoxaline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1H-Pyrrolo[2,3-b]quinoxaline, 2-phenyl-; Aloisine-Related Compound 7; 2-phenyl-1H-pyrrolo[3,2-b]quinoxaline; BDBM7384; CHEMBL307392; SCHEMBL5942610; CTK2A2915; DTXSID70424875; 2-phenylpyrrolo[2,3-b]quinoxaline; ZINC13492983
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
5-Benzoyl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334782; BDBM50428456
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[3-[4-[[Amino-[4-chloro-3-(trifluoromethyl)anilino]methylidene]amino]anilino]phenyl]acetamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290699; BDBM50019436
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
6-(3,5-Dichlorophenyl)-5H-pyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76660; SCHEMBL490777; 6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 20; BDBM7352; 5H-Pyrrolo[2,3-b]pyrazine, 6-(3,5-dichlorophenyl)-; 6-(3,5-dichlorophenyl)[5h]pyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
4-Chloro-1-(4,5-dichlorothiophen-3-yl)butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL595728; BDBM50304460
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(4-Oxo-2-phenyl-2,3-dihydro-1,5-benzothiazepin-5-yl)methyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334792; BDBM50428466
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
1-(5-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}thiophen-2-yl)ethan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-purine deriv. 14; CHEMBL379618; BDBM10649
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
Thiadiazolidinone (TDZD) deriv. 28
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL26000; BDBM7801; ethyl (5Z)-5-[(ethoxycarbonyl)imino]-4-phenyl-3-sulfanylidene-1,2,4-thiadiazolidine-2-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[29] | |||
| Compound Name |
Acetophenone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Phenylethanone; Methyl phenyl ketone; Phenyl methyl ketone; Acetylbenzene; Ethanone, 1-phenyl-; Benzoyl methide; Hypnone; Acetophenon; 1-phenylethan-1-one; Acetylbenzol; 1-Phenyl-1-ethanone; Benzoylmethide; Benzene, acetyl-; Acetofenon; Ketone, methyl phenyl; methylphenylketone; 1-phenyl-ethanone; USAF EK-496; Acetofenon [Czech]; Phenylethanone; RCRA waste number U004; Hypnon; phenylmethylketone; NSC 7635; Dymex; RCRA waste no. U004; UNII-RK493WHV10; AI3-00575; Ketone, methyl phenyl-; CHEMBL274467; RK493WHV10; 4-acetyl-benzene; MFCD00008724; DSSTox_CID_1828; Acetophenone, 98%, pure; DSSTox_RID_76353; DSSTox_GSID_21828; FEMA Number 2009; FEMA No. 2009; CCRIS 1341; HSDB 969; EINECS 202-708-7; aceto phenone; aceto-phenone; acetyl-benzen; Acetyl-Benzene; alpha-Acetophenone; Ethanone,1-phenyl; methyl-phenyl ketone; Methyl phenyl-Ketone; nchem.180-comp5; 1-Phenylethanone, 9CI; SCHEMBL737; ACMC-209sb9; bmse000286; EC 202-708-7; WLN: 1VR; KSC448E4P; Acetophenone, >=98%, FG; ARONIS25343; SCHEMBL8170205; 1-Phenylethanone (acetophenone); DTXSID6021828; SCHEMBL13341485; Acetophenone, analytical standard; FEMA 2009; NSC7635; Acetophenone, >=98.0% (GC); Acetophenone, natural, 98%, FG; ZINC896628; HY-Y0989; NSC-7635; Tox21_202422; Tox21_300343; Acetophenone, ReagentPlus(R), 99%; ANW-40963; BDBM50236986; c0117; s5528; SBB040241; AKOS000119011; CCG-266074; DB04619; MCULE-4710225344; KS-00000W90; KS-0000477P; NCGC00248000-01; NCGC00248000-02; NCGC00254370-01; NCGC00259971-01; AK110129; SC-18041; SC-32943; DB-044220; 624-EP2270006A1; 624-EP2272835A1; 624-EP2272844A1; 624-EP2275411A2; 624-EP2275418A1; 624-EP2275427A1; 624-EP2284165A1; 624-EP2301923A1; 624-EP2301983A1; 624-EP2305672A1; 624-EP2305682A1; 624-EP2308848A1; 624-EP2308851A1; 624-EP2308857A1; 624-EP2308865A1; 624-EP2308869A1; 624-EP2308879A1; 624-EP2311846A1; 624-EP2314295A1; 624-EP2314558A1; 624-EP2314583A1; 624-EP2371831A1; A0061; CS-0015982; FT-0628908; FT-0636694; FT-0637564; FT-0641367; FT-0661057; ST45054137; Acetophenone, puriss. p.a., >=99.0% (GC); C07113; 36678-EP2308851A1; 36678-EP2311801A1; 36678-EP2311802A1; 36678-EP2311803A1; 36678-EP2371814A1; 37407-EP2311802A1; 37407-EP2311803A1; Q375112; J-519533; Z57127548; F0001-2322
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
Ethyl 2-thiophenecarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ethyl thiophene-2-carboxylate; Ethyl 2-thenoate; Thiophene-2-carboxylic acid ethyl ester; Ethyl2-thiophenecarboxylate; 2-Thiophenecarboxylic Acid Ethyl Ester; Thiophenecarboxylic acid, ethyl ester; Ethyl-thiophene-2-carboxylate; CHEMBL595062; MFCD00005436; Ethyl-2-thiophenecarboxylate; EINECS 220-554-9; ACMC-209h0w; ethylthiophene-2-carboxylate; ethyl thiophen-2-carboxylate; ethyl 2-thiophene carboxylate; ethyl-2-thiophene carboxylate; KSC489S4R; BIDD:GT0076; SCHEMBL422787; CTK3I9948; DTXSID10182381; ZINC157298; Ethyl 2-thiophenecarboxylate, 95%; KS-000001ZK; NSC39455; ANW-26334; BDBM50304452; NSC-39455; SBB058448; AKOS008947879; MCULE-4538513975; VT20388; 2-Thiophenecarboxylic acid, ethyl ester; AC-18071; AK-88539; AS-59780; SC-75520; AB0015188; DB-000574; A5369; FT-0625796; ST50308270; J-016971
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
5-Benzyl-2-methyl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334784; BDBM50428454; MCULE-8343650909; SR-01000098774; SR-01000098774-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-(6-(4-Nitrophenyl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1083837; N-[6-(4-nitrophenyl)-1H-indazol-3-yl]butanamide; SCHEMBL6486431; BDBM50313692; N-[[6-(4-nitrophenyl)-1H-indazol-3-yl]]butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
5-Methyl-6-phenylpyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine; Aloisine-Related Compound 48; CHEMBL78232; BDBM7389; SCHEMBL6487576; ZINC13492987
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
Chembl4284711
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50469291
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
N-(9H-Carbazol-9-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL592930; N-carbazol-9-ylbenzamide; BDBM50304444
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1-[3-[[4-(Diaminomethylideneamino)phenyl]methyl]phenyl]-2-phenylguanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290691; BDBM50019454
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
1-[3-[4-(Diaminomethylideneamino)phenoxy]phenyl]-2-phenylguanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290690; BDBM50019453
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-Arylpurine deriv. 10
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL210839; BDBM10645; N-(4-{6-[(2-methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}phenyl)methanesulfonamide; N-[4-[6-(2-methoxyethylamino)-9-propan-2-ylpurin-2-yl]phenyl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
2-[3-[4-(Diaminomethylideneamino)benzoyl]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290432; BDBM50019442
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N-[3-[4-[[Amino-[4-chloro-3-(trifluoromethyl)anilino]methylidene]amino]phenoxy]phenyl]acetamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290698; BDBM50019432
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
Ethyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL573425; BDBM50300049
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
N-(6-(4-Chlorophenyl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1086426; N-[6-(4-chlorophenyl)-1H-indazol-3-yl]butanamide; SCHEMBL1461243; BDBM50313695
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
1H-1,2,4-Triazole, 1,3,5-triphenyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,3,5-Triphenyl-1,2,4-triazole; CHEMBL596411; 1,3,5-Triphenyl-1H-1,2,4-triazole; 1,3,5-Triphenyl-1,2,4-triazol; SCHEMBL2339443; CTK0G6401; DTXSID90340285; BDBM50304441; 1,3,5-Triphenyl-1H-[1,2,4]triazole; 1,3,5-Triphenyl-1H-1,2,4-triazole #
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
5-Benzyl-2-pyridin-3-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334785; BDBM50428453
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
4-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-arylpurine deriv. 8; CHEMBL379029; BDBM10643
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
5-Butyl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334780; BDBM50428458
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
4-Chloro-1-(5-chlorothiophen-2-yl)butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596446; 1-Butanone, 4-chloro-1-(5-chloro-2-thienyl)-; SCHEMBL11196961; CTK1I6697; DTXSID20517908; BBL032467; BDBM50304454; MFCD14530467; STL243285; ZINC36161255; AKOS016368964; MCULE-4157590200; VS-11279; 4-Chloro-(5-Chloro-2-Thienyl)-1-Butanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[3-[2-(2-Methylpyridin-4-yl)-4-oxo-5H-thieno[3,2-c]pyridin-7-yl]phenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1809108; BDBM50419002
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1223203; BDBM50325369; 4-(6-(cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(dimethylamino)ethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-[4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenoxy]phenyl]-4,5-dihydro-1H-imidazol-2-amine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290435; BDBM50019446
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
4-[4-(4-Methoxy-2-pyridin-4-ylthieno[3,2-c]pyridin-7-yl)phenyl]morpholine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1809112; BDBM50418997
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
2-Chloro-1-(4-methylthiophen-2-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Chloromethyl Thienyl Ketone deriv. 12; BDBM7864; CHEMBL423377; Ethanone, 2-chloro-1-(4-methyl-2-thienyl)- (9CI); SCHEMBL6790693; ZINC13528252; 2-Chloro-1-(4-methyl-2-thienyl)ethanone; 2-Chloro-1-(4-methyl-thiophen-2-yl)-ethanone; 2-chloro-1-(4-methylthiophen-2-yl)ethan-1-one; 2-CHLORO-1-(4-METHYL-2-THIENYL)-ETHANONE
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
Ethyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL594822; BDBM50304450
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(6-(4-Methoxyphenyl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1086425; N-[6-(4-methoxyphenyl)-1H-indazol-3-yl]butanamide; SCHEMBL1461499; BDBM50313693
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
5-(Ethylthio)-1,3-diphenyl-1H-benzo[f][1,2,4]triazepine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL595496; BDBM50304439
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
Dtxsid40986859
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596399; 1-(4-Chlorothiophen-2-yl)propan-2-amine--hydrogen chloride (1/1)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
5-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}thiophene-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-purine deriv. 15; CHEMBL209404; BDBM10650; 5-[6-(2-methoxyethylamino)-9-propan-2-ylpurin-2-yl]thiophene-2-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
2-[4-[3-(Diaminomethylideneamino)anilino]phenyl]-1-phenylguanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290689; BDBM50019452
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
5-(Cyclohexylmethyl)-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334781; BDBM50428457
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
5-[(2-Chlorophenyl)methyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334788; BDBM50428470
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
4-(6-{[(4-Methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-purine deriv. 17; CHEMBL377061; BDBM10651
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
5-Propan-2-yl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2207945; BDBM50401961
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
4-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}-N-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-arylpurine deriv. 11; CHEMBL437325; BDBM10646; 4-[6-(2-methoxyethylamino)-9-propan-2-ylpurin-2-yl]-N-methylbenzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
1-(4-Bromophenyl)-2-hydroxyethan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(4-bromophenyl)-2-hydroxyethanone; 4'-Bromo-2-hydroxyacetophenone; Ethanone,1-(4-bromophenyl)-2-hydroxy-; 1-(4-Bromophenyl)-2-hydroxy-1-ethanone; CHEMBL1801618; MFCD00174275; 1-(4-Bromophenyl)-2-hydroxyethane-1-one; p-Bromphenacylalkohol; zlchem 616; Ethanone, 1-(4-bromophenyl)-2-hydroxy-; SCHEMBL55916; p-Bromo-a-hydroxy acetophenone; CTK4H0583; DTXSID40334412; ZLD0066; alpha-Hydroxy-4'-bromoacetophenone; ZINC167257; ACT05833; KS-00001X4R; ANW-55081; BDBM50347515; SBB068790; AKOS005070623; 1-(4-bromophenyl)-2-hydroxy-ethanone; MCULE-5747207409; VZ20926; 1-(4-bromophenyl)-2-oxidanyl-ethanone; SY130953; DB-018547; FT-0605657; 4X-0729; A821774; J-503250; 4 inverted exclamation mark -Bromo-2-hydroxyacetophenone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
1-(4-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}phenyl)ethan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-arylpurine deriv. 9; CHEMBL208017; BDBM10644
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
3-Chloro-9-nitroso-carbazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL595748; 3-chloro-9-nitroso-9H-carbazole; BDBM50304445
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
TCMDC-136678; CHEMBL588573; BDBM50325372; 4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(dimethylamino)ethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
3,6-Diamino-2-(4-chlorobenzoyl)-4-(2-iodophenyl)thieno[2,3-b]pyridine-5-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2313821; Oprea1_107850; Oprea1_804702; SCHEMBL1539850; BDBM50424221; STK725766; ZINC33355350; AKOS005524273; MCULE-7383740589; EU-0051729; AE-848/31937053; SR-01000519087; SR-01000519087-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290692; BDBM50019455
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N-[3-[4-Oxo-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)-5H-thieno[3,2-c]pyridin-7-yl]phenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1809109; BDBM50418986
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
1-Bromo-4-(chloromethylsulfinyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1801621; BDBM50347518
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-Chloro-1-(2,5-dimethylthiophen-3-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-chloro-1-(2,5-dimethyl-3-thienyl)ethanone; 2-chloro-1-(2,5-dimethylthien-3-yl)ethanone; 2-chloro-1-(2,5-dimethylthiophen-3-yl)ethan-1-one; 1-(2,5-dimethyl(3-thienyl))-2-chloroethan-1-one; 2-chloro-1-(2,5-dimethylthiophen-3-yl)-ethanone; Ethanone,2-chloro-1-(2,5-dimethyl-3-thienyl)-; BDBM7862; CHEMBL344719; SCHEMBL6788403; CTK4G7705; ZINC42569; DTXSID80350414; ALBB-008698; MFCD00224200; STK505510; AKOS000321623; Chloromethyl Thienyl Ketone deriv. 10; MCULE-3101204871; ST020051; FT-0679412; R2663; EN300-13278; J-508583; Z90122359
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[4-[3-(Diaminomethylideneamino)benzoyl]phenyl]-1-phenylguanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290687; BDBM50019450
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-(Furan-2-yl)-5-propan-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2207947; BDBM50401958
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
5-(2-Fluorobenzyl)-2-phenyl-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1397048; HMS1835K12; BDBM50428471; AKOS001866654; MCULE-2346104986; NCGC00112345-01; C714-0242; F0670-0242; 5-(2-fluorobenzyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
Chembl4283719
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50469293
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
1-(5-Bromothiophen-2-yl)-4-chlorobutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL594556; 4-Chloro-1-(5-bromo-thien-2-yl)butan-1-one; SCHEMBL6609187; BDBM50304455; MFCD14532152; ZINC36174345; AKOS022273848
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[3-[[4-(Diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290433; BDBM50019444
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
Ethyl benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzoic acid, ethyl ester; Benzoic ether; Ethyl benzenecarboxylate; Benzoic Acid Ethyl Ester; ethylbenzoate; Benzoyl ethyl ether; Ethylester kyseliny benzoove; Benzoic acid, C9-11-alkyl esters; Benzoic acid, C12-13-alkyl esters; Benzoic acid, C14-15-alkyl esters; UNII-J115BRJ15H; MFCD00009109; CHEMBL510714; J115BRJ15H; BENZOIC ACID,ETHYL ESTER; Ethyl benzoate, 99+%; Ethyl benzoate (natural); (Ethyl benzoate)tricarbonylchromium; FEMA No. 2422; NSC 8884; EINECS 202-284-3; Ethylester kyseliny benzoove [Czech]; AI3-01352; benzoic acid ethyl; Ethylbenzenecarboxylate; benzoic acid ethylester; Ethyl Benzoate Natural; ACMC-209rny; Benzoic acid-ethyl ester; Ethyl benzoate, >=99%; WLN: 2OVR; EC 202-284-3; DSSTox_CID_18696; DSSTox_RID_79386; DSSTox_GSID_38696; SCHEMBL55674; KSC486S1D; DTXSID3038696; Ethyl benzoate, puriss., 98%; CTK3I6911; FEMA 2422; KS-00000WFQ; NSC8884; ZINC404389; Ethyl benzoate, analytical standard; NSC-8884; Tox21_302021; ANW-40124; BBL010500; BDBM50304448; SBB058595; STK025151; Ethyl benzoate, >=99%, FCC, FG; AKOS003596787; EBD2860833; MCULE-1461486723; NCGC00255586-01; VS-02532; DB-002644; B0069; Ethyl benzoate, natural, >=99%, FCC, FG; FT-0622709; ST50824225; Ethyl benzoate, Vetec(TM) reagent grade, 98%; 27848-EP2272817A1; 27848-EP2281810A1; 27848-EP2314587A1; 27848-EP2371831A1; Q421100; J-502070; Z53835169; F8880-7461
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(6-(4-Ethylphenyl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1077270; N-[6-(4-ethylphenyl)-1H-indazol-3-yl]butanamide; SCHEMBL6485745; BDBM50313694; N-[[6-(4-ethylphenyl)-1H-indazol-3-yl]]butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355482; BDBM50043416; ZINC17334508; AKOS008571954; Z31474376
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
Naringin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Naringoside; Naringin hydrate; UNII-N7TD9J649B; Naringenin 7-O-neohesperidoside; Naringenine-7-rhamnosidoglucoside; 4'5-diOH-Flavone-7-rhgluc; CHEMBL451532; N7TD9J649B; Naringenin 7-Rhamnoglucoside; C27H32O14; MFCD00148888; aurantiin; Naringenin-7-beta-neohesperidoside; Naringenin 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside]; EINECS 233-566-4; (2S)-Naringin; AI3-19008; 4',5,7-trihydroxyflavanone 7-rhamnoglucoside; SR-01000736681; Naringenin,(S); yphenyl)chroman-4-one; Naringin (Naringoside); Prestwick0_000467; Prestwick1_000467; Prestwick2_000467; Prestwick3_000467; SCHEMBL23432; BSPBio_000574; cid_25075; MLS000069459; BIDD:ER0262; DivK1c_000247; SPBio_002513; BPBio1_000632; cid_442428; GTPL4738; MEGxp0_001877; 3-Bromo-4-isopropoxybenzoicacid; DTXSID6022478; ACon1_000139; HMS500M09; KBio1_000247; NINDS_000247; HMS2231M18; HY-N0153; ZINC8143604; BDBM50241582; s2329; AKOS016034302; CCG-208591; CS-5632; MCULE-5348711723; IDI1_000247; NCGC00142617-01; NCGC00142617-02; NCGC00142617-03; AS-12929; SMR000059108; ST072162; N2371; C09789; J10148; 236N472; Q418469; SR-01000736681-4; SR-01000736681-5; BRD-K02953697-001-09-2; BRD-K02953697-002-03-3; Naringenin 7-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside; naringenin 7-O-(alpha-L-rhamnosyl-(1,2)-beta-D-glucoside)
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[2] | |||
| Compound Name |
4-Cyclohexyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thiadiazolidinone (TDZD) deriv. 7; CHEMBL24167; BDBM7780
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
2-Arylpurine deriv. 12
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL207426; BDBM10647; N-(2-cyanoethyl)-4-{6-[(2-methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}benzamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
3-Methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC368288; Aloisine-Related Compound 8; SCHEMBL490618; BDBM7388; CHEMBL311935; DTXSID10419604; ZINC6491783; NSC-368288; DS-005725; 3-methyl-6-phenyl[5h]pyrrolo[2,3-b]pyrazine; 5H-PYRROLO[2,3-B]PYRAZINE,3-METHYL-6-PHENYL-
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
5,6-Dimethoxy-1-indanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; 5,6-Dimethoxyindan-1-one; 5,6-Dimethoxy-indan-1-one; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-; 5,6-dimethoxy-2,3-dihydroinden-1-one; 5,6-dimethoxyindanone; MFCD00003790; 5,6-dimethoxy indanone; UNII-F805RZI8GO; F805RZI8GO; CHEMBL611356; NSC401450; PubChem8855; 5,6 Dimethoxy indanone; 5,6dimethoxyindan-1-one; 5, 6 Dimethoxy indanone; ACMC-209fh9; 5,6 dimethoxy-1-indanone; 5,6 dimethoxyindan-1-one; 5,6-Dimethoxy-1-Indanone (Donepezil Impurity); DSSTox_CID_31469; DSSTox_RID_97354; DSSTox_GSID_57680; KSC201Q9F; SCHEMBL354177; 1-Indanone, 5,6-dimethoxy-; 1-Indanone, 5,6-dimethoxy-,; DTXSID9057680; CTK1A1892; AM845; HMS1665M05; ZINC164394; 5,6-Dimethoxy-1-indanone, 97%; ACT08215; BCP08893; CS-D1431; KS-000001FU; EINECS 218-287-8; Tox21_113806; ANW-24331; BBL012470; BDBM50304446; SBB066967; STK741969; AKOS000279828; AC-1195; GF-0120; MCULE-6811953967; NSC 401450; NSC-401450; NCGC00253682-01; AK-34075; BR-34075; SC-02421; SY013700; DB-025380; A4570; D3313; FT-0619825; ST50308464; AZ0001-0314; 07D699; B-7836; 5,6-bis(methyloxy)-2,3-dihydro-1H-inden-1-one; BRD-K48252171-001-01-7; Q27277789
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
5-Methyl-7-(4-morpholin-4-ylphenyl)-2-pyridin-4-ylthieno[3,2-c]pyridin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1809111; BDBM50418988
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
2-[[4-[[[5-(2,3-Difluorophenyl)-1H-indazole-3-carbonyl]amino]methyl]piperidin-1-yl]methyl]-1,3-oxazole-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3735986; SCHEMBL15223355
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[31] | |||
| Compound Name |
1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)benzoyl]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290693; BDBM50019456
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
4-Bromophenacylamine hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Amino-4'-bromoacetophenone hydrochloride; 2-amino-1-(4-bromophenyl)ethanone Hydrochloride; 2-Amino-4'-bromoacetophenone HCl; MFCD00051998; Ethanone, 2-amino-1-(4-bromophenyl)-, hydrochloride; A-AMINO-4'-BROMOACETOPHENONE; 2-amino-1-(4-bromophenyl)ethan-1-one; 2-Amino-1-(4-bromophenyl)ethan-1-one hydrochloride; Ethanone, 2-amino-1-(4-bromophenyl)-; 2-Amino-1-(4-bromophenyl)-1-ethanone hydrochloride; 2-AMINO-4-BROMOACETOPHENONE HYDROCHLORIDE; CHEMBL1801613; 2-amino-1-(4-bromophenyl)ethan-1-one, chloride; 2-Amino-4'-bromoacetophenone hydrochloride, 97%; PubChem16820; ACMC-20a2ne; 2-AMINO-4'-BROMOACETOPHENONEHYDROCHLORIDE; SCHEMBL203985; 4-Bromophenacylaminehydrochloride; CTK7E1848; p-bromophenacylamine hydrochloride; BCP24959; KS-00000C5X; NSC25405; ANW-54360; CCG-45828; NSC-25405; SBB100801; AKOS005069361; AS05065; CM11121; CS-W009051; LS11597; MCULE-5778719759; 2-Amino-1-(4-bromophenyl)ethanone HCl; 2-Amino-1-(4-bromophenyl)ethanone, HCl; AC-24722; AK-42272; BC004154; SC-28431; SY028321; 2-Amino-1-(4-bromo-phenyl)-ethanone HCl; AB0014564; FT-0617908; ST50319465; 2-Amino-1-(4-bromo-phenyl)-ethanone HCl salt; amino-(4'bromo) acetophenone hydrochloride salt; M-4552; 2-amino-1-(4-bromophenyl)ethanone;hydrochloride; amino-(4' bromo) acetophenone hydrochloride salt; 2-Amino-4'-bromoacetophenone hydrochloride, 96%; 2-AMINO-4'-BROMOACETOPHENONE?HYDROCHLORIDE; 644A044; 10Z-0719; 2-Amino-1-(4-bromo-phenyl)-ethanone hydrochloride; 2-AMINO-4\\'-BROMOACETOPHENONE HYDROCHLORIDE; ALPHA-AMINO-4-BROMOACETOPHENONE HYDROCHLORIDE; SR-01000635574-1; 2-amino-1-(4-bromo-phenyl)ethan-1-one hydrochloride; 2-amino-1-(4-bromophenyl)ethanone hydrochloride salt; 2-amino-1-(4-bromo-phenyl)-ethanone hydrochloric acid salt; 2-Amino-4 inverted exclamation mark -bromoacetophenone Hydrochloride
Click to Show/Hide
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||||
| Activity |
IC50 = 100000 nM
|
[16] | |||
| Compound Name |
2-(4,5-Dichlorothiophen-3-yl)-2-oxoethyl acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL595729; BDBM50304461
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenyl]-[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]methanone;hydrochloride
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290436; BDBM50019447
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|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-(2-pyrrolidin-1-ylethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222474; BDBM50325373; 4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
3,6-Diamino-2-benzoyl-4-(2-methoxyphenyl)thieno[2,3-b]pyridine-5-carbonitrile
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314102; SCHEMBL1539786; BDBM50424226
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|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
(4S,6E,12E)-18-Hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1668418; BDBM50336459
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|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
Chembl4294709
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BDBM50469284
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|
||||
| Activity |
IC50 = 100000 nM
|
[23] | |||
| Compound Name |
4-[6-[(3-Chlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222992; BDBM50325368; (S)-4-(6-(3-chlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
2-[4-Chloro-3-(trifluoromethyl)phenyl]-1-[3-[4-(diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290696; BDBM50019428
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-[(4-Oxo-2-phenyl-2,3-dihydro-1,5-benzothiazepin-5-yl)methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334787; BDBM50428451
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|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
1-Chloro-4-(2-chloro-1-sulfinylethyl)benzene
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3746962
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|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-Arylpurine deriv. 13
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL379811; BDBM10648; methyl N-(4-{6-[(2-methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}phenyl)carbamate
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
2-[3-[4-(Diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290431; BDBM50019441
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
5-Ethyl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2207944; BDBM50401962
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
2-[2-(4-Bromophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1801612; 2-(2-(4-BROMOPHENYL)-2-OXOETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE; NSC132386; SCHEMBL14711680; CTK5E6805; DTXSID80299738; ZINC1719682; BDBM50347509; STK265190; AKOS000849335; MCULE-4944745865; NSC-132386; N-(beta-Oxo-4-bromophenethyl)phthalimide; ST50540357; 2-[2-(4-bromophenyl)-2-oxoethyl]benzo[c]azoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione,2-[2-(4-bromophenyl)-2-oxoethyl]-; 2-[2-(4-bromophenyl)-2-oxoethyl]-2,3-dihydro-1H-isoindole-1,3-dione
Click to Show/Hide
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||||
| Activity |
IC50 = 100000 nM
|
[16] | |||
| Compound Name |
Thiophene-2-carbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Thiophenecarboxaldehyde; 2-Thenaldehyde; Thiophene-2-aldehyde; 2-FORMYLTHIOPHENE; 2-Thiophenealdehyde; Thiophene-2-carboxaldehyde; 2-Thienylaldehyde; 2-Thiophenecarbaldehyde; formylthiophene; 2-Thienylcarboxaldehyde; 2-Thienaldehyde; alpha-Formylthiophene; 2-Thiophene carboxaldehyde; 2-Thiophenaldehyde; Thenaldehyde; alpha-Thiophenecarboxaldehyde; .alpha.-Formylthiophene; 2-thiophencarboxaldehyde; 2-thienal; NSC 2162; MFCD00005429; thiophenecarboxaldehyde; thiophen-2-carbaldehyde; 2-thiophene carbaldehyde; 2-Carboxaldehyde-thiophene; 2-thiophene carboxyaldehyde; .alpha.-Thiophenecarboxaldehyde; CHEMBL328441; 2-Thiophenecarboxaldehyde, 98%; Thiophene-2-Aldehyde (T-2-A); EINECS 202-629-8; thiophenaldehyde; a-Thenaldehyde; thiophenealdehyde; AI3-16611; thien-2-aldehyde; 2-formyl-thiophene; thiophen-2-aldehyde; 2-thiophene aldehyde; 2-thiophene-aldehyde; thien-2-carbaldehyde; 2-thiophencarbaldehyde; 2-Thiophenic aldehyde; alpha -formylthiophene; thiophene carboxaldehyde; thiophen 2-carbaldehyde; thiophen-2 carbaldehyde; Thiophenecarbox-aldehyde; thiophene 2-carbaldehyde; thiophen-2-carboxaldehyde; UNII-IW05BB9XBM; 2-thiophene-carboxaldehyde; thiopbene-2-carboxaldehyde; IW05BB9XBM; WLN: T5SJ BVH; 2-thienyl-2-carbaldehyde;; EC 202-629-8; SCHEMBL31206; alpha -thiophenecarboxaldehyde; KSC124M1P; Thiophene-2-aldehyde (T2A); BIDD:GT0227; DTXSID7052656; KS-00000AXQ; NSC2162; ZINC158751; EBD50474; NSC-2162; ANW-13662; BBL027524; BDBM50071926; GEO-02313; SBB004321; STL194296; AKOS000119051; AC-4923; CS-W013657; HY-W012941; LS40350; MCULE-8254409353; PS-9245; AK-26482; BP-10496; BR-26482; SC-07484; SY001071; DB-057703; AM20120394; FT-0613442; ST50213387; EN300-18990; 98T624; M-5822; 2-Thiophenecarboxaldehyde, (stabilized with HQ); 82913-EP2284157A1; 82913-EP2298758A1; 82913-EP2298759A1; 82913-EP2305664A1; A845794; W-100098; W-204260; Q27159509; F2190-0580
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[4-(2-Bromoacetyl)phenyl]indene-1,3-dione
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3745772; BDBM50134240
Click to Show/Hide
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||||
| Activity |
IC50 = 100000 nM
|
[4] | |||
| Compound Name |
2-Chloro-1-(5-methylthiophen-2-yl)ethanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
2-Chloro-1-(5-methyl-thiophen-2-yl)-ethanone; Ethanone,2-chloro-1-(5-methyl-2-thienyl)-; 2-chloro-1-(5-methylthiophen-2-yl)ethan-1-one; 2-chloro-1-(5-methylthien-2-yl)ethanone; ACMC-209hot; Ethanone,2-chloro-1-(5-methyl-2-thienyl)-(9CI); BDBM7860; CHEMBL142415; Ethanone, 2-chloro-1-(5-methyl-2-thienyl)- (9CI); SCHEMBL3926030; CTK4G7704; DTXSID10407041; ZINC4206206; ANW-27195; MFCD00464874; Chloromethyl Thienyl Ketone deriv. 8; AKOS000200779; Chloromethyl 5-methyl-2-thienyl ketone; MCULE-9549471755; DA-26696; FT-0709719; V5115; EN300-13126; K-7465; Z89283294
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[4-[[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenyl]methyl]phenyl]-4,5-dihydro-1H-imidazol-2-amine;hydrochloride
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290437; BDBM50019448
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
4'-Chloroacetophenone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
1-(4-Chlorophenyl)ethanone; 4-Chloroacetophenone; P-CHLOROACETOPHENONE; Ethanone, 1-(4-chlorophenyl)-; Acetophenone, 4'-chloro-; 4-Acetylchlorobenzene; 1-(4-Chlorophenyl)Ethan-1-One; p-Chloracetophenone; p-Acetylchlorobenzene; USAF DO-1; 1-(4-Chlorophenyl)-ethanone; Methyl p-chlorophenyl ketone; p-Chlorophenyl methyl ketone; 4-Chlorophenyl methyl ketone; Methyl 4-chlorophenyl ketone; MFCD00000624; chloroacetophenone-4; UNII-ZV4A71K303; 4-chloro acetophenone; 1-acetyl-4-chlorobenzene; 1-(4-chloro-phenyl)-ethanone; CHEMBL608419; ZV4A71K303; Acetophenone, 4'-chloro- (8CI); 4'-Chloroacetophenone, 98+%; HSDB 2088; NSC 6115; EINECS 202-800-7; BRN 0386014; AI3-01370; p-choroacetophenone; 4-chloracetophenone; p'-chloroacetophenone; p-chloro-acetophenone; 4-chloroace-tophenone; 4`-Chloroacetophenone; PubChem3297; 4\\'-Chloroacetophenone; ACMC-209sef; bmse000518; WLN: GR DV1; SCHEMBL75640; 4-07-00-00639 (Beilstein Handbook Reference); KSC680O9R; 4'-Chloroacetophenone, 97%; DTXSID1052668; CTK5I0798; 1-(4-chlorophenyl)ethane-1-one; 4-CHLORO-1-ACETYLBENZENE; NSC6115; ZINC896324; ACT00279; NSC-6115; 3,4,5-tris(benzyloxy)benzylalcohol; ANW-41077; BBL013140; BDBM50304447; LABOTEST-BB LT01147632; SBB040243; STK400323; AKOS000118934; ZINC100500256; AS05257; CM11155; CS-W016264; MCULE-1728385439; SC-07564; AM20050032; FT-0617963; ST50213403; C06647; M-6154; A846097; Q-200456; Q27295903; Z57127462; F2147-0328
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-(4-Bromophenyl)-2-oxoethyl acetate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
4-Bromophenacyl acetate; [2-(4-bromophenyl)-2-oxoethyl] acetate; CHEMBL1801617; p-bromophenacyl acetate; Maybridge1_000103; MixCom1_000191; CBDivE_001746; (4-Bromobenzoyl)methyl acetate; 1,4-DIPYRROLIDINOBENZENE; SCHEMBL11757716; CTK2I0659; KS-00000MFI; DTXSID90322102; ZINC128874; 1666AC; BDBM50347514; MFCD00174274; NSC400447; SBB101819; AKOS016010243; DS-3885; MCULE-9872833423; NSC-400447; [2-(4-Bromophenyl)-2-oxo-ethyl]acetate; AK114718; [2-(4-bromophenyl)-2-oxo-ethyl] acetate; DB-074934; FT-0608594; Ethanone, 2-(acetyloxy)-1-(4-bromophenyl)-; BRD-K26026143-001-01-6; ACETIC ACID 2-(4-BROMO-PHENYL)-2-OXO-ETHYL ESTER
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[4-(Diaminomethylideneamino)anilino]phenyl]guanidine;hydrochloride
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290434; BDBM50019445
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
5-Benzyl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334783; SCHEMBL8853517; BDBM50428455; CCG-31229; SR-01000098748; SR-01000098748-1
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
4,5-Dibromothiophene-2-carbaldehyde
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
4,5-DIBROMOTHIOPHENE-2-CARBOXALDEHYDE; 4,5-Dibromo-thiophene-2-carbaldehyde; CHEMBL596225; MFCD00225242; ACMC-1AFPX; 4,5-Dibromo-2-thenaldehyde; SCHEMBL947395; 4,5-dibromo-2-formylthiophene; CTK1C5431; DTXSID80355661; ZINC325339; 4,5-dibromo-2-thiophenecarbaldehyde; BBL038242; BDBM50304449; SBB003040; STK301552; AKOS000307926; CS-W014034; MCULE-1830087204; QC-5963; VT20262; AS-62462; DB-049233; FT-0639429; ST45061243; EN300-92302
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(S)-4-(6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222990; BDBM50325375
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
Chembl4276946
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
GTPL9965; compound 3a [Pipionne et al, 2018]; 1-[5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl]ethan-1-one
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
WAY-262611; MAY-262611; CHEMBL570667; [1-(4-naphthalen-2-ylpyrimidin-2-yl)piperidin-4-yl]methanamine; [1-[4-(2-naphthalenyl)-2-pyrimidinyl]-4-piperidinyl]methanamine; C20H22N4; {1-[4-(naphthalen-2-yl)pyrimidin-2-yl]piperidin-4-yl}methanamine; SCHEMBL3647243; BCP10871; EX-A2096; BDBM50303037; ZINC43203108; AKOS026750289; CCG-208093; CS-3286; MAY 262611; NCGC00386713-03; NCGC00386713-06; AK547007; AS-56174; DA-33417; HY-11035; FT-0718137; Y1889; BRD-K37885773-001-01-9; Q27216163; ({1-[4-(2-naphthyl)pyrimidin-2-yl]piperidin-4-yl}methyl)amine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
2-[4-[4-(Diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290430; BDBM50019437
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
1-(4-Bromophenyl)-2-phenylsulfanylethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1801615; SCHEMBL9787308; ZINC5604173; BDBM50347512; AKOS008908599; MCULE-7271670773; 1-(4-bromophenyl)-2-phenylthioethan-1-one; ST51025428
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(2-Furyl)-5-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1492321; MLS000093161; HMS1651G13; HMS2447A20; BDBM50401959; SMR000028790; SR-01000134167; SR-01000134167-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222565; BDBM50325374; (S)-4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
2-[4-Chloro-3-(trifluoromethyl)phenyl]-1-[3-[[4-(diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290697; BDBM50019429
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)anilino]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290695; BDBM50019460
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N''-(2-((2-Chlorophenyl)(imino)methyl)phenyl)-N''-phenylbenzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL595727; BDBM50304440
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[4-[[3-(Diaminomethylideneamino)phenyl]methyl]phenyl]-1-phenylguanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290688; BDBM50019451
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-[4-[3-(Diaminomethylideneamino)phenoxy]phenyl]-1-phenylguanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290438; BDBM50019449
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[[3-(diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290694; BDBM50019459
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2420909; BDBM50439464; 9-(9H-purin-6-yl)-1,9-diazaspiro[5.5]undecane; Q27465376; SIJ
Click to Show/Hide
|
||||
| Activity |
IC50 = 138000 nM
|
[24] | |||
| Compound Name |
4-Methoxy-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99423; 4-methoxypaullone; NSC701591; Paullone Analog 50; BDBM7311; SCHEMBL5688599; CTK7B0388; NSC 701591; NSC-701591; NCI60_036441; 4-methoxy-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5h)-one; 4-Methoxy-7,12-dihydroindolo[3,2-d][1]benzazepine-6(5H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 139958.73 nM
|
[43] | |||
| Compound Name |
1-[(4-Methoxyphenyl)methyl]-3-[6-(2H-tetrazol-5-yl)-1,3-benzothiazol-2-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1824332; BDBM50352494
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[44] | |||
| Compound Name |
N-(6-(4-Hydroxyphenyl)-5-(pyridin-3-yl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1092802; SCHEMBL6486735; BDBM50313671; N-[5-(3-pyridyl)-6-(4-hydroxyphenyl)-1H-indazol-3-yl]butanamide; N-[6-(4-oxocyclohexa-2,5-dien-1-ylidene)-5-pyridin-3-yl-1,2-dihydroindazol-3-yl]butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 149000 nM
|
[19] | |||
| Compound Name |
Chembl4288015
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50465052; 13-Methylpodocarpa-8,11,13-triene-19-ol; J3.646.506I
Click to Show/Hide
|
||||
| Activity |
IC50 = 178000 nM
|
[45] | |||
| Compound Name |
Paullone Analog 51
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7312; CHEMBL331759; SCHEMBL1394643; ZINC13532079; NSC 708241; 9-bromo-5,6,7,12-tetrahydro-benzo[6,7]cyclohept[1,2-b]indole; 14-bromo-18-azatetracyclo[9.7.0.0;{2,7}.0;{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaene
Click to Show/Hide
|
||||
| Activity |
IC50 = 179887.09 nM
|
[43] | |||
| Compound Name |
4-{5-[(4-Iodobenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
oxadiazole-pyridyl containing compound 13; CHEMBL37652; BDBM8553; SCHEMBL5024078; STK292973; ZINC13442470; AKOS000368369; MCULE-4562027296; 2-(4-Iodobenzylthio)-5-(4-pyridyl)-1,3,4-oxadiazole; 2-{[(4-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl)-1,3,4-oxadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 198000 nM
|
[46] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 34 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Lithium chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
LITHIUM CHLORIDE; 7447-41-8; Lithiumchloride; Lithium chloride (LiCl); LiCl; chlorure de lithium; Chlorku litu; chlorolithium; Lithiumchlorid; Chlorku litu [Polish]; Luthium chloride; Chlorure de lithium [French]; CCRIS 5924; UNII-G4962QA067; HSDB 4281; EINECS 231-212-3; lithium(1+) ion chloride; NSC 327172; CHEMBL69710; CHEBI:48607; NSC327172; MFCD00011078; G4962QA067; Lithium chloride, 99%, extra pure; ClLi; Lithium chloride, 99+%, ACS reagent; Lithium chloride, 99%, for molecular biology; Lithium chloride, 99%, for analysis, anhyd
Click to Show/Hide
|
||||
| Activity |
EC50 > 3000000 nM
|
[47] | |||
| Compound Name |
3-({[5-(Pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}methyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CBKinase1_004794; CBKinase1_017194; BDBM8556; CHEMBL288588; KUC113220N; ZINC574201; STK132992; AKOS005403746; CCG-203444; MCULE-5638564296; KSC-334-046-; oxadiazole-pyridyl containing compound 16; BRD-K58370951-001-01-0; 3-[5-(4-Pyridyl)-1,3,4-oxadiazole-2-ylthiomethyl]benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 235000 nM
|
[46] | |||
| Compound Name |
Schembl22374664
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311235; BDBM50046524
Click to Show/Hide
|
||||
| Activity |
IC50 = 240000 nM
|
[48] | |||
| Compound Name |
1-(4-Amino-1,2,5-oxadiazol-3-yl)-N-methyl-5-(piperidin-1-ylmethyl)-N-(2-pyridin-4-ylethyl)triazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL113447; SCHEMBL7428548; BDBM50130723
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[25] | |||
| Compound Name |
1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-[(2-methylpropylamino)methyl]-N-(pyridin-4-ylmethyl)triazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL114582; BDBM50130729
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[25] | |||
| Compound Name |
2-[4-({[5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-yl]sulfanyl}methyl)phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
thiadiazole-pyridyl containing compound 6; CHEMBL39357; BDBM8546; 4-[5-(2-Pyridyl)-1,3,4-thiadiazole-2-ylthiomethyl]benzeneacetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[46] | |||
| Compound Name |
2-[4-({[5-(Pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
triazole-pyridyl containing compound 4; CHEMBL40842; BDBM8544; 4-[5-(4-Pyridyl)-4H-1,2,4-triazole-3-ylthiomethyl]benzeneacetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[46] | |||
| Compound Name |
2-[4-({[5-(Pyridin-3-yl)-1,3,4-thiadiazol-2-yl]sulfanyl}methyl)phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
thiadiazole-pyridyl containing compound 5; CHEMBL39803; BDBM8545; 4-[5-(3-Pyridyl)-1,3,4-thiadiazole-2-ylthiomethyl]benzeneacetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[46] | |||
| Compound Name |
2-({[3-(5-Methyl-1,2,4-oxadiazol-3-yl)phenyl]methyl}sulfanyl)-5-(pyridin-4-yl)-1,3,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
oxadiazole-pyridyl containing compound 17; CHEMBL37826; BDBM8557
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[46] | |||
| Compound Name |
(2S)-2-(1H-Indol-3-ylmethyl)-2,4-dihydro-1H-pyrido[2,3-b]pyrazin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3986013; BDBM50192838
Click to Show/Hide
|
||||
| Activity |
IC50 = 322000 nM
|
[49] | |||
| Compound Name |
10-Pyridin-2-yl-8-thiophen-2-yl-5,7-dihydrobenzo[d][1]benzazepine-6-thione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL331502
Click to Show/Hide
|
||||
| Activity |
IC50 = 349945.17 nM
|
[43] | |||
| Compound Name |
4-(1H-Indol-3-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Meridianin G; 2-AMINO-4-(3-INDOLYL)PYRIMIDINE; 2-Pyrimidinamine, 4-(1H-indol-3-yl)-; 6-debromomeridianin D; CHEMBL48082; SCHEMBL573402; SCHEMBL4564892; BDBM10844; CTK0J1681; DTXSID90328003; 4-indol-3-ylpyrimidine-2-ylamine; 3-(2-aminopyrimidin-4-yl) indole; ALBB-017157; ZINC1864765; MFCD11058049; NSC712012; STL259853; AKOS000345321; MCULE-4572117832; NSC-712012; AS-35708; AB0073689; ST45184806
Click to Show/Hide
|
||||
| Activity |
IC50 = 350000 nM
|
[26] | |||
| Compound Name |
6-Methoxy-4-methyl-N-(quinolin-8-ylmethyl)-5-[3-(trifluoromethyl)phenoxy]quinolin-8-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311239; BDBM50046525
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[48] | |||
| Compound Name |
4-(1H-Indol-2-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
isomeridianin G; CHEMBL50226; BDBM10846
Click to Show/Hide
|
||||
| Activity |
IC50 = 420000 nM
|
[26] | |||
| Compound Name |
5-Methyl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2207943; BDBM50401963
Click to Show/Hide
|
||||
| Activity |
IC50 = 480000 nM
|
[33] | |||
| Compound Name |
Paullone Analogue 61
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7326; CHEMBL331722; NSC 718541; 6,5-(5-Chloro-1,2-phenyleneimino)-9H-pyrido[2,3-b]azepine-8(7H)-one; 9-Chloro-7,12-dihydro-pyrido[2 ,3 :2,3]azepino[4,5-b]-indol-6(5H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 500034.53 nM
|
[43] | |||
| Compound Name |
1-[(4-Methoxyphenyl)methyl]-3-[4-(2H-tetrazol-5-yl)pyridin-2-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1824334; BDBM50352493
Click to Show/Hide
|
||||
| Activity |
IC50 = 510000 nM
|
[44] | |||
| Compound Name |
Pentyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL583199; BDBM50300046
Click to Show/Hide
|
||||
| Activity |
IC50 = 600000 nM
|
[37] | |||
| Compound Name |
Ditert-butyl 9-bromo-6-oxo-7H-indolo[3,2-d][1]benzazepine-5,12-dicarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL317562; Paullone Analog 54; BDBM7315; SCHEMBL5688664; NSC 702374; 9-bromo-5,12-bis-(tert-butyloxycarbonyl)-paullone; 9-Bromo-6-oxo-6,7-dihydroindolo[3,2-d][1]benzoazepine-5,12-dicarboxylic acid di-tert-butyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 639734.84 nM
|
[43] | |||
| Compound Name |
2-[[1-Cyclopentyl-5-[1-(Oxetan-3-Yl)piperidin-4-Yl]pyrazol-3-Yl]amino]pyridine-4-Carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3629013; GTPL9989; SCHEMBL22137472; BDBM50128294; AKOS032960466; compound 11 [PMID: 26431428]; Q27455367; 2-(1-Cyclopentyl-5-(1-(oxetane-3-yl)-4-piperidinyl)-1H-pyrazole-3-ylamino)pyridine-4-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 = 682000 nM
|
[50] | |||
| Compound Name |
Propyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL573145; BDBM50300048
Click to Show/Hide
|
||||
| Activity |
IC50 = 700000 nM
|
[37] | |||
| Compound Name |
8-[(4-Hydroxyphenyl)methylamino]-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-6-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311242; BDBM50046526
Click to Show/Hide
|
||||
| Activity |
IC50 = 750000 nM
|
[48] | |||
| Compound Name |
2-(2-Thienyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2207942; 2-(Thiophen-2-yl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one; 2-(thiophen-2-yl)-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one; C13H11NOS2; Oprea1_439594; SCHEMBL14273765; CTK5A8742; 2-thiophen-2-yl-3,5-dihydro-2H-1,5-benzothiazepin-4-one; DTXSID50402651; 6117AE; BDBM50401964; MFCD01927811; SBB102446; AKOS005071070; MCULE-2389086366; NE22491; KS-0000204O; FT-0680625; EN300-37119; 7Z-0202; 2,3-Dihydro-2-(2-thienyl)-1,5-benzothiazepin-4(5H)-one; 2-(Thiophen-2-yl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one; 2-(2-thienyl)-2H,3H,5H-benzo[b]1,4-thiazaperhydroepin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 830000 nM
|
[33] | |||
| Compound Name |
6-Methoxy-4-phenyl-[1]benzofuro[2,3-b]pyridin-3-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2163768; BDBM50395889
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[51] | |||
| Compound Name |
Octyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL578640; BDBM50300044
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[37] | |||
| Compound Name |
8-Methoxy-12-phenyl-13-phenylmethoxy-17-oxa-15-azatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,8,11,13,15-octaene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221391
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[52] | |||
| Compound Name |
3,6-Dimethoxy-4-phenyl-[1]benzofuro[2,3-b]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2163773; BDBM50395891
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[51] | |||
| Compound Name |
Paullone Analogue 69
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7334; CHEMBL331120; NSC 716784; 12-Methyl-6-methylthio-9-nitro-7,12-dihydro-indolo-[3,2-d][1]benzazepine
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[43] | |||
| Compound Name |
4-(5-Bromo-1H-indol-2-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
isomeridianin C; CHEMBL48081; BDBM10845; 4-(5-Bromo-1H-indole-2-yl)pyrimidine-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[3] | |||
| Compound Name |
1-(4-Cyanopyridin-2-yl)-3-[(4-methoxyphenyl)methyl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1824539; BDBM50352491
Click to Show/Hide
|
||||
| Activity |
IC50 = 1430000 nM
|
[44] | |||
| Compound Name |
N-(5,6-Diphenyl-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1093746; N-(5,6-diphenyl-1H-indazol-3-yl)butanamide; N-[5,6-diphenyl-1H-indazol-3-yl]butanamide; SCHEMBL1461843; BDBM50313677
Click to Show/Hide
|
||||
| Activity |
IC50 = 1720000 nM
|
[19] | |||
| Compound Name |
Lithium ion
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
lithium cation; Lithium(1+); Lithium, ion (Li1+); lithium, ion; UNII-8H8Z5UER66; Li(+); 8H8Z5UER66; Lithium ions; Lithium(+); Lithium element; lithium(I); lithium(I) cation; Lithium (I) ion; lithium(1+) ion; Li(+) cation; Li(+) ion; CHEMBL1234004; DTXSID10169612; BDBM50259153; DB01356; MCULE-6872461833; Q66760324
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[53] | |||
| Compound Name |
1-[(4-Methoxyphenyl)methyl]-3-(6-nitro-1,3-benzothiazol-2-yl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1824540; BDBM50352492
Click to Show/Hide
|
||||
| Activity |
IC50 = 3640000 nM
|
[44] | |||
| Compound Name |
N-(5,6-Bis(4-phenoxyphenyl)-1H-indazol-3-yl)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1077244; BDBM50313675
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[19] | |||
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway. ACS Med Chem Lett. 2010 Sep 7;1(9):454-9. | ||||
| REF 2 | Flavonoids as lead compounds modulating the enzyme targets in Alzheimer's disease. Med Chem Res. 2012 Nov 21;22:3061-75. | ||||
| REF 3 | Meridianins, a new family of protein kinase inhibitors isolated from the ascidian Aplidium meridianum. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1703-7. | ||||
| REF 4 | Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease. Eur J Med Chem. 2016 Jan 1;107:63-81. | ||||
| REF 5 | Structure-Based Design of Potent and Selective CK1gamma Inhibitors. ACS Med Chem Lett. 2012 Oct 18;3(12):1059-64. | ||||
| REF 6 | Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett. 2012 Feb 9;3(2):146-150. | ||||
| REF 7 | Synthesis of new dipyrrolo- and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1-5, GSK-3) inhibitors. Eur J Med Chem. 2009 Feb;44(2):708-16. | ||||
| REF 8 | First dual AK/GSK-3 inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents. Eur J Med Chem. 2017 Sep 29;138:438-457. | ||||
| REF 9 | Identification of lead small molecule inhibitors of glycogen synthase kinase-3 beta using a fragment-linking strategy. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5669-5673. | ||||
| REF 10 | 3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles are selective inhibitors of Plasmodium falciparum glycogen synthase kinase-3. J Med Chem. 2013 Jan 10;56(1):264-75. | ||||
| REF 11 | Discovery of novel, dual mechanism ERK inhibitors by affinity selection screening of an inactive kinase. J Med Chem. 2014 Nov 13;57(21):8817-26. | ||||
| REF 12 | Angiogenesis inhibitors identified by cell-based high-throughput screening: synthesis, structure-activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation. Bioorg Med Chem. 2012 Feb 15;20(4):1442-60. | ||||
| REF 13 | Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools. Bioorg Med Chem. 2009 Oct 1;17(19):6914-25. | ||||
| REF 14 | The sulfamide moiety affords higher inhibitory activity and oral bioavailability to a series of coumarin dual selective RAF/MEK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6223-7. | ||||
| REF 15 | Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1353-7. | ||||
| REF 16 | Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds. J Med Chem. 2011 Jun 23;54(12):4042-56. | ||||
| REF 17 | Imidazo[1,2-a]pyrazine diaryl ureas: inhibitors of the receptor tyrosine kinase EphB4. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6991-5. | ||||
| REF 18 | (1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: a wingless beta-catenin agonist that increases bone formation rate. J Med Chem. 2009 Nov 26;52(22):6962-5. | ||||
| REF 19 | Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1985-9. | ||||
| REF 20 | Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2. Bioorg Med Chem Lett. 2005 Feb 15;15(4):863-7. | ||||
| REF 21 | Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases. Bioorg Med Chem Lett. 2014 May 1;24(9):2206-11. | ||||
| REF 22 | Novel aryl and heteroaryl substituted N-[3-(4-phenylpiperazin-1-yl)propyl]-1,2,4-oxadiazole-5-carboxamides as selective GSK-3 inhibitors. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3661-6. | ||||
| REF 23 | Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 (GSK-3). Bioorg Med Chem. 2018 Nov 1;26(20):5479-5493. | ||||
| REF 24 | Synthesis and evaluation of heteroaryl substituted diazaspirocycles as scaffolds to probe the ATP-binding site of protein kinases. Bioorg Med Chem. 2013 Sep 15;21(18):5707-24. | ||||
| REF 25 | Synthesis and in vitro characterization of 1-(4-aminofurazan-3-yl)-5-dialkylaminomethyl-1H-[1,2,3]triazole-4-carboxylic acid derivatives. A new class of selective GSK-3 inhibitors. J Med Chem. 2003 Jul 17;46(15):3333-41. | ||||
| REF 26 | Fragment and knowledge-based design of selective GSK-3beta inhibitors using virtual screening models. Eur J Med Chem. 2009 Jun;44(6):2361-71. | ||||
| REF 27 | 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1) inhibitors. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5392-5. | ||||
| REF 28 | 5-Aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1989-94. | ||||
| REF 29 | First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease. J Med Chem. 2002 Mar 14;45(6):1292-9. | ||||
| REF 30 | Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 (GSK-3). Eur J Med Chem. 2013 Mar;61:95-103. | ||||
| REF 31 | Hit Optimization of 5-Substituted-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamides: Potent Glycogen Synthase Kinase-3 (GSK-3) Inhibitors with in Vivo Activity in Model of Mood Disorders. J Med Chem. 2015 Nov 25;58(22):8920-37. | ||||
| REF 32 | Synthesis and biological evaluation of novel 4-azaindolyl-indolyl-maleimides as glycogen synthase kinase-3beta (GSK-3beta) inhibitors. Bioorg Med Chem. 2009 Jul 1;17(13):4302-12. | ||||
| REF 33 | Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3beta inhibitors through virtual screening. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7232-6. | ||||
| REF 34 | Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects. J Med Chem. 2003 Jan 16;46(2):222-36. | ||||
| REF 35 | Guanidinium-based derivatives: searching for new kinase inhibitors. Eur J Med Chem. 2014 Jun 23;81:427-41. | ||||
| REF 36 | Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3144-6. | ||||
| REF 37 | Development of 5-benzylpaullones and paullone-9-carboxylic acid alkyl esters as selective inhibitors of mitochondrial malate dehydrogenase (mMDH). Eur J Med Chem. 2010 Jan;45(1):335-42. | ||||
| REF 38 | Identification of 2-(4-pyridyl)thienopyridinones as GSK-3 inhibitors. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4823-7. | ||||
| REF 39 | Discovery of imidazo[1,2-b]pyridazine derivatives as IKKbeta inhibitors. Part 1: Hit-to-lead study and structure-activity relationship. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5113-8 | ||||
| REF 40 | Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation. ACS Med Chem Lett. 2014 Aug 7;6(1):53-7 | ||||
| REF 41 | Isosteric replacement of the Z-enone with haloethyl ketone and E-enone in a resorcylic acid lactone series and biological evaluation. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1167-70. | ||||
| REF 42 | N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK. Medchemcomm. 2018 Apr 12;9(6):963-968. | ||||
| REF 43 | Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones. J Med Chem. 2004 Jan 1;47(1):22-36. | ||||
| REF 44 | Synthesis and biological evaluation of glycogen synthase kinase 3 (GSK-3) inhibitors: an fast and atom efficient access to 1-aryl-3-benzylureas. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5610-5. | ||||
| REF 45 | Ca 2+-Signal Transduction Inhibitors, Kujiol A and Kujigamberol B, Isolated from Kuji Amber Using a Mutant Yeast. J Nat Prod. 2018 Apr 27;81(4):1070-1074. | ||||
| REF 46 | Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1525-8. | ||||
| REF 47 | 3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3245-50. | ||||
| REF 48 | Syntheses, neural protective activities, and inhibition of glycogen synthase kinase-3 of substituted quinolines. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3392-7. | ||||
| REF 49 | Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3beta. ACS Med Chem Lett. 2016 Jul 14;7(9):852-6. | ||||
| REF 50 | Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12). J Med Chem. 2015 Oct 22;58(20):8182-99. | ||||
| REF 51 | Multitargeted drug development: Discovery and profiling of dihydroxy substituted 1-aza-9-oxafluorenes as lead compounds targeting Alzheimer disease relevant kinases. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6914-8. | ||||
| REF 52 | Novel aspects in structure-activity relationships of profiled 1-aza-9-oxafluorenes as inhibitors of Alzheimer's disease-relevant kinases cdk1, cdk5 and gsk3beta. Medchemcomm. 2012;3:1413-8. | ||||
| REF 53 | Natural and synthetic bioactive inhibitors of glycogen synthase kinase. Eur J Med Chem. 2017 Jan 5;125:464-477. | ||||
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