TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T70977	Glycogen synthase kinase-3 beta	D0I9HF	Hesperidin	Approved	10621	C28H34O15	610.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O	IC50 = 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	D0J9ZR	Niclosamide	Approved	4477	C13H8Cl2N2O4	327.12	C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O	IC50 = 77500 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	D05ADP	R-roscovitine	Phase 2	160355	C19H26N6O	354.4	CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3	IC50 = 130000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B05YHM	3-(3,4-Dimethoxyphenyl)-1,5,7-triazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one	Investigative	25268198	C17H15N3O3	309.32	COC1=C(C=C(C=C1)C2=CNC3=C2N4C=CC=C4C(=O)N3)OC	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B06BNS	Chembl4208804	Investigative	145965154	C25H19NO2	365.4	C1C(OC2=CC=CC=C2N1C(=O)C3=CC=CC=C3)C4=CC=CC5=CC=CC=C54	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0AY8H	N-[2-[2-(1H-Indol-3-yl)ethylamino]-2-oxoethyl]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide	Investigative	134148934	C20H19N5O2	361.4	C1=CC=C2C(=C1)C(=CN2)CCNC(=O)CNC(=O)C3=CN=C4C(=C3)C=CN4	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0F5XW	3,6-Diamino-2-(3-chlorobenzoyl)-4-(2-iodophenyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	51347682	C21H12ClIN4OS	530.8	C1=CC=C(C(=C1)C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC(=CC=C4)Cl)N)N)C#N)I	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0G6KY	Chembl4277269	Investigative	145983700	C28H22N2O3S	466.6	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3[N+](=O)[O-])C4=CC=C(C=C4)C5=CC=CC=C5	IC50 = 51000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0GL5N	2-Phenyl-1H-pyrrolo[2,3-b]quinoxaline	Investigative	6538806	C16H11N3	245.28	C1=CC=C(C=C1)C2=CC3=NC4=CC=CC=C4N=C3N2	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0J2MI	5-Benzoyl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578239	C20H15NO2S2	365.5	C1C(SC2=CC=CC=C2N(C1=O)C(=O)C3=CC=CC=C3)C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0KW1R	N-[3-[4-[[Amino-[4-chloro-3-(trifluoromethyl)anilino]methylidene]amino]anilino]phenyl]acetamide;hydrochloride	Investigative	90644407	C22H20Cl2F3N5O	498.3	CC(=O)NC1=CC=CC(=C1)NC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0QBL7	3-(1-(3-(1H-Imidazol-1-yl)propyl)-1H-indol-3-yl)-1-phenyl-4-(1H-pyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione	Investigative	45267453	C31H24N6O2	512.6	C1=CC=C(C=C1)N2C(=O)C(=C(C2=O)N3C=CC4=C3C=CC=N4)C5=CN(C6=CC=CC=C65)CCCN7C=CN=C7	IC50 ~ 73340 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0TAZ2	6-(3,5-Dichlorophenyl)-5H-pyrrolo[2,3-b]pyrazine	Investigative	6538776	C12H7Cl2N3	264.11	C1=CN=C2C(=N1)C=C(N2)C3=CC(=CC(=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0TVS6	2-Chloro-1-(3,4,5-tribromo-thiophen-2-yl)-ethanol	Investigative	12373568	C6H4Br3ClOS	399.33	C(C(C1=C(C(=C(S1)Br)Br)Br)O)Cl	IC50 = 75000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0XE2Q	Chembl4209197	Investigative	145966583	C17H15NO4	297.3	CCN1C2=CC3=C(C=C2OC(C1=O)C4=CC=CC=C4)OCO3	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0XKW1	1-[(4-Methoxyphenyl)methyl]-3-[6-(2H-tetrazol-5-yl)-1,3-benzothiazol-2-yl]urea	Investigative	53388145	C17H15N7O2S	381.4	COC1=CC=C(C=C1)CNC(=O)NC2=NC3=C(S2)C=C(C=C3)C4=NNN=N4	IC50 = 140000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B0ZRX4	4-Chloro-1-(4,5-dichlorothiophen-3-yl)butan-1-one	Investigative	46227238	C8H7Cl3OS	257.6	C1=C(C(=C(S1)Cl)Cl)C(=O)CCCCl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B18RKH	3-[(4-Oxo-2-phenyl-2,3-dihydro-1,5-benzothiazepin-5-yl)methyl]benzoic acid	Investigative	71578312	C23H19NO3S	389.5	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC(=CC=C3)C(=O)O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B1E3PY	N-(6-(4-Hydroxyphenyl)-5-(pyridin-3-yl)-1H-indazol-3-yl)butyramide	Investigative	135848026	C22H20N4O2	372.4	CCCC(=O)NC1=NNC2=CC(=C(C=C21)C3=CN=CC=C3)C4=CC=C(C=C4)O	IC50 = 149000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B1FC4T	1-(5-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}thiophen-2-yl)ethan-1-one	Investigative	23645302	C17H21N5O2S	359.4	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(S3)C(=O)C)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B1JF2K	Chembl4212073	Investigative	145964815	C20H15NO4	333.3	CN1C2=CC3=C(C=C2OC(C1=O)C4=CC=CC5=CC=CC=C54)OCO3	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B1V2YU	Thiadiazolidinone (TDZD) deriv. 28	Investigative	9604910	C14H15N3O4S2	353.4	CCOC(=O)/N=C\\1/N(C(=S)N(S1)C(=O)OCC)C2=CC=CC=C2	IC50 = 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B1XOY0	Chembl4279152	Investigative	145980531	C27H27N3O4S	489.6	CCN(CC)C(=O)C1=CC=C(C=C1)C2CC(=O)N(C3=CC=CC=C3S2)CC4=CC=CC=C4[N+](=O)[O-]	IC50 = 90000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B2FAM4	Acetophenone	Investigative	7410	C8H8O	120.15	CC(=O)C1=CC=CC=C1	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B2FP6Q	Ethyl 2-thiophenecarboxylate	Investigative	76052	C7H8O2S	156.2	CCOC(=O)C1=CC=CS1	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B2Q9CN	5-Benzyl-2-methyl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	20878104	C17H17NOS	283.4	CC1CC(=O)N(C2=CC=CC=C2S1)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B31ENR	5-[(2-Bromophenyl)methyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578309	C22H18BrNOS	424.4	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3Br)C4=CC=CC=C4	IC50 = 73900 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B3A9GH	(3r)-1-{2-[4-(4-Acetylphenyl)piperazin-1-Yl]-2-Oxoethyl}-N-(3-Chloro-4-Hydroxyphenyl)pyrrolidine-3-Carboxamide	Investigative	58985201	C25H29ClN4O4	485	CC(=O)C1=CC=C(C=C1)N2CCN(CC2)C(=O)CN3CC[C@H](C3)C(=O)NC4=CC(=C(C=C4)O)Cl	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B3BYK5	N-(6-(4-Nitrophenyl)-1H-indazol-3-yl)butyramide	Investigative	22319556	C17H16N4O3	324.33	CCCC(=O)NC1=NNC2=C1C=CC(=C2)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B3EJA6	5-Methyl-6-phenylpyrrolo[2,3-b]pyrazine	Investigative	6538810	C13H11N3	209.25	CN1C(=CC2=NC=CN=C21)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B3HNZ9	Chembl4284711	Investigative	145991711	C28H29N5O4S	531.6	CN1CCN(CC1)NC(=O)C2=CC=C(C=C2)C3CC(=O)N(C4=CC=CC=C4S3)CC5=CC=CC=C5[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B3I1VW	N-(9H-Carbazol-9-yl)benzamide	Investigative	46227247	C19H14N2O	286.3	C1=CC=C(C=C1)C(=O)NN2C3=CC=CC=C3C4=CC=CC=C42	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B3PAC6	1-[3-[[4-(Diaminomethylideneamino)phenyl]methyl]phenyl]-2-phenylguanidine;hydrochloride	Investigative	90644434	C21H23ClN6	394.9	C1=CC=C(C=C1)N=C(N)NC2=CC=CC(=C2)CC3=CC=C(C=C3)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B3QRP5	1-[3-[4-(Diaminomethylideneamino)phenoxy]phenyl]-2-phenylguanidine;hydrochloride	Investigative	90644432	C20H21ClN6O	396.9	C1=CC=C(C=C1)N=C(N)NC2=CC(=CC=C2)OC3=CC=C(C=C3)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B40YPB	2-Arylpurine deriv. 10	Investigative	23645298	C18H24N6O3S	404.5	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(C=C3)NS(=O)(=O)C)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B43WPI	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325478	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B46CZS	2-[3-[4-(Diaminomethylideneamino)benzoyl]phenyl]guanidine;hydrochloride	Investigative	90644412	C15H17ClN6O	332.79	C1=CC(=CC(=C1)N=C(N)N)C(=O)C2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B4UF9E	2-(Chloroacetyl)thiophene	Investigative	2757925	C6H5ClOS	160.62	C1=CSC(=C1)C(=O)CCl	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B50MZP	Paullone Analog 51	Investigative	5331128	C17H14BrN	312.2	C1CC2=CC=CC=C2C3=C(C1)C4=C(N3)C=CC(=C4)Br	IC50 = 179887.09 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B54YHZ	N-[3-[4-[[Amino-[4-chloro-3-(trifluoromethyl)anilino]methylidene]amino]phenoxy]phenyl]acetamide;hydrochloride	Investigative	90644405	C22H19Cl2F3N4O2	499.3	CC(=O)NC1=CC(=CC=C1)OC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B5ECR3	Triazolo[1,5-a]pyrimidine 17	Investigative	11488074	C23H25N7O2S	463.6	C1CC(CCC1N)NC2=NC3=NC=NN3C(=C2)NC4=CC=C(C=C4)S(=O)(=O)C5=CC=CC=C5	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B5KW1A	2-Bromo-1-(4-bromophenyl)ethanone O-methyl oxime	Investigative	10902866	C9H9Br2NO	306.98	CO/N=C(\\CBr)/C1=CC=C(C=C1)Br	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B5ON0T	6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	Investigative	70789254	C14H20N6	272.35	C1CCNC2(C1)CCN(CC2)C3=NC=NC4=C3NC=N4	IC50 = 138000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B5S0AV	Ethyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate	Investigative	44818784	C19H16N2O3	320.3	CCOC(=O)C1=CC2=C(C=C1)NC3=C2CC(=O)NC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B5SU0T	Chembl4288015	Investigative	132575131	C18H26O	258.399	CC1=CC2=C(C=C1)[C@]3(CCC[C@]([C@@H]3CC2)(C)CO)C	IC50 = 178000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B5WPZ6	4-(Methyl(4-(5-methylthiophen-2-yl)pyrimidin-2-yl)amino)benzenesulfonamide	Investigative	44550927	C16H16N4O2S2	360.5	CC1=CC=C(S1)C2=NC(=NC=C2)N(C)C3=CC=C(C=C3)S(=O)(=O)N	IC50 = 65000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B5X8YL	2-(4-Bromophenyl)-5-[(2-nitrophenyl)methyl]-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578380	C22H17BrN2O3S	469.4	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3[N+](=O)[O-])C4=CC=C(C=C4)Br	IC50 = 67800 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B64FYX	N-(6-(4-Chlorophenyl)-1H-indazol-3-yl)butyramide	Investigative	22319587	C17H16ClN3O	313.8	CCCC(=O)NC1=NNC2=C1C=CC(=C2)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B64TUS	2-(4-Chlorophenyl)-5-[(2-nitrophenyl)methyl]-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578379	C22H17ClN2O3S	424.9	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3[N+](=O)[O-])C4=CC=C(C=C4)Cl	IC50 = 71000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B67WOT	1H-1,2,4-Triazole, 1,3,5-triphenyl-	Investigative	563249	C20H15N3	297.4	C1=CC=C(C=C1)C2=NN(C(=N2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B6FCR7	5-Benzyl-2-pyridin-3-yl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	46843861	C21H18N2OS	346.4	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B6HT4X	4-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}benzaldehyde	Investigative	15604545	C18H21N5O2	339.4	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(C=C3)C=O)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B6M3KV	N-(5-(Furan-3-yl)-6-(4-hydroxyphenyl)-1H-indazol-3-yl)butyramide	Investigative	135848030	C21H19N3O3	361.4	CCCC(=O)NC1=NNC2=CC(=C(C=C21)C3=COC=C3)C4=CC=C(C=C4)O	IC50 = 98000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B6VL8T	5-Butyl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578237	C17H19NOS2	317.5	CCCCN1C(=O)CC(SC2=CC=CC=C21)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B6W8MH	Chembl4285999	Investigative	145992429	C24H20N2O5S	448.5	COC(=O)C1=CC=CC(=C1)C2CC(=O)N(C3=CC=CC=C3S2)CC4=CC=CC=C4[N+](=O)[O-]	IC50 = 66000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B6WXP9	4-Chloro-1-(5-chlorothiophen-2-yl)butan-1-one	Investigative	13091616	C8H8Cl2OS	223.12	C1=C(SC(=C1)Cl)C(=O)CCCCl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B70BXA	N-[3-[2-(2-Methylpyridin-4-yl)-4-oxo-5H-thieno[3,2-c]pyridin-7-yl]phenyl]methanesulfonamide	Investigative	56667018	C20H17N3O3S2	411.5	CC1=NC=CC(=C1)C2=CC3=C(S2)C(=CNC3=O)C4=CC(=CC=C4)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B70UGI	Chembl4203063	Investigative	145977262	C25H19NO2	365.4	C1=CC=C(C=C1)CN2C3=CC=CC=C3OC(C2=O)C4=CC=CC5=CC=CC=C54	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B7MO4E	4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide	Investigative	24959046	C21H26N6O	378.5	CN(C)CCNC(=O)C1=CC=C(C=C1)C2=CN=C3N2N=C(C=C3)NCC4CC4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B7N1WR	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325479	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B7ORT6	3-(3,4-Dichlorophenyl)-5-oxa-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one	Investigative	25268558	C15H8Cl2N2O2	319.1	C1=CN2C(=C1)C(=O)NC3=C2C(=CO3)C4=CC(=C(C=C4)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B83SIE	3-(3,4-Dimethoxyphenyl)-5-oxa-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one	Investigative	25268559	C17H14N2O4	310.3	COC1=C(C=C(C=C1)C2=COC3=C2N4C=CC=C4C(=O)N3)OC	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B84EBL	N-[4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenoxy]phenyl]-4,5-dihydro-1H-imidazol-2-amine;hydrochloride	Investigative	90644418	C18H21ClN6O	372.9	C1CN=C(N1)NC2=CC=C(C=C2)OC3=CC=CC(=C3)NC4=NCCN4.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B8JVD5	3-(3,4-Dimethoxy-phenyl)-furo[2,3-b]pyrrolizin-8-one	Investigative	11437879	C17H13NO4	295.29	COC1=C(C=C(C=C1)C2=COC3=C2N4C=CC=C4C3=O)OC	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B8M7TL	4-[4-(4-Methoxy-2-pyridin-4-ylthieno[3,2-c]pyridin-7-yl)phenyl]morpholine	Investigative	56680584	C23H21N3O2S	403.5	COC1=NC=C(C2=C1C=C(S2)C3=CC=NC=C3)C4=CC=C(C=C4)N5CCOCC5	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B8W0CK	3-(4-Chlorophenyl)-1,5,7-triazatricyclo[7.3.0.02,6]dodeca-2(6),3,9,11-tetraen-8-one	Investigative	25268197	C15H10ClN3O	283.71	C1=CN2C(=C1)C(=O)NC3=C2C(=CN3)C4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B9BI2U	2-Chloro-1-(4-methylthiophen-2-yl)ethanone	Investigative	6539178	C7H7ClOS	174.65	CC1=CSC(=C1)C(=O)CCl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B9K3YR	Ethyl 3-hydroxy-4,5-dimethylthiophene-2-carboxylate	Investigative	54728388	C9H12O3S	200.26	CCOC(=O)C1=C(C(=C(S1)C)C)O	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	B9OES1	1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea	Investigative	11755812	C26H20F3N7O	503.5	C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CN4C=CN=C4C(=N3)NCC5=CC=NC=C5	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BA5PF8	N-(6-(4-Methoxyphenyl)-1H-indazol-3-yl)butyramide	Investigative	22319558	C18H19N3O2	309.4	CCCC(=O)NC1=NNC2=C1C=CC(=C2)C3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BA9I3M	1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-amine	Investigative	25216880	C19H20N4	304.4	C1CN(CCC1N)C2=NC=CC(=N2)C3=CC4=CC=CC=C4C=C3	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BAU0O8	5-(Ethylthio)-1,3-diphenyl-1H-benzo[f][1,2,4]triazepine	Investigative	46227236	C22H19N3S	357.5	CCSC1=NC(=NN(C2=CC=CC=C21)C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BAZ4M3	Dtxsid40986859	Investigative	46227246	C7H11Cl2NS	212.14	CC(CC1=CC(=CS1)Cl)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BB89YJ	N-[6-(4-Hydroxyphenyl)-5-phenyl-1H-indazol-3-yl]butanamide	Investigative	135566516	C23H21N3O2	371.4	CCCC(=O)NC1=NNC2=CC(=C(C=C21)C3=CC=CC=C3)C4=CC=C(C=C4)O	IC50 = 55000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BBD25S	5-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}thiophene-2-carbonitrile	Investigative	23645303	C16H18N6OS	342.4	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(S3)C#N)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BBG6Q5	2-[4-[3-(Diaminomethylideneamino)anilino]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644430	C20H22ClN7	395.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)NC3=CC(=CC=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BC0R6N	Chembl4213595	Investigative	145964437	C22H17NO4	359.4	C1OC2=C(O1)C(=C3C(=C2)NC(=O)C(O3)C4=CC=CC=C4)CC5=CC=CC=C5	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BC9D3Q	5-(Cyclohexylmethyl)-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578238	C20H23NOS2	357.5	C1CCC(CC1)CN2C(=O)CC(SC3=CC=CC=C32)C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BCN14P	N-(6-Chloro-5-(pyridin-4-yl)-1H-indazol-3-yl)butyramide	Investigative	22319680	C16H15ClN4O	314.77	CCCC(=O)NC1=NNC2=CC(=C(C=C21)C3=CC=NC=C3)Cl	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BCV61T	5-[(2-Chlorophenyl)methyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578308	C22H18ClNOS	379.9	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BCY4H7	3-(3-(Benzyloxy)-4-methoxyphenyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one	Investigative	11245667	C23H18N2O3	370.4	COC1=C(C=C(C=C1)C2=CNC3=C2N4C=CC=C4C3=O)OCC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BD01KI	4-(6-{[(4-Methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl)benzaldehyde	Investigative	15604546	C23H23N5O2	401.5	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(C=C3)C=O)NCC4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BD3YQ2	Chembl4215567	Investigative	145972558	C17H15NO2	265.31	CC1=CC=C(C=C1)C2=C(NC3=CC=CC=C32)OC(=O)C	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BEC98L	2-(5-Methoxy-2-phenoxypyrimidin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one	Investigative	71457515	C18H16N4O3	336.3	COC1=CN=C(N=C1C2=CC3=C(N2)CCNC3=O)OC4=CC=CC=C4	IC50 ~ 62500 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BEG6Y8	2-[2-[2-(4-Fluorophenyl)ethyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one	Investigative	71450358	C21H20FN3O2	365.4	COC1=C(C=C(N=C1)CCC2=CC=C(C=C2)F)C3=CC4=C(N3)CCNC4=O	IC50 ~ 62500 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BELU74	5-Propan-2-yl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71450733	C16H17NOS2	303.4	CC(C)N1C(=O)CC(SC2=CC=CC=C21)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BEOM13	4-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}-N-methylbenzamide	Investigative	23645299	C19H24N6O2	368.4	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(C=C3)C(=O)NC)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BF19RN	1-(4-Bromophenyl)-2-hydroxyethan-1-one	Investigative	520633	C8H7BrO2	215.04	C1=CC(=CC=C1C(=O)CO)Br	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BF23DJ	1-(4-{6-[(2-Methoxyethyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}phenyl)ethan-1-one	Investigative	23645297	C19H23N5O2	353.4	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(C=C3)C(=O)C)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BF45RX	1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-(piperidin-1-ylmethyl)-N-(2-pyridin-4-ylethyl)triazole-4-carboxamide	Investigative	10250197	C18H23N9O2	397.4	C1CCN(CC1)CC2=C(N=NN2C3=NON=C3N)C(=O)NCCC4=CC=NC=C4	EC50 = 57530 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BF5T1N	3-(4-Chlorophenyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one	Investigative	11380176	C15H9ClN2O	268.7	C1=CN2C(=C1)C(=O)C3=C2C(=CN3)C4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BF8I1G	5-[(2-Methylphenyl)methyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578310	C23H21NOS	359.5	CC1=CC=CC=C1CN2C(=O)CC(SC3=CC=CC=C32)C4=CC=CC=C4	IC50 = 76100 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BFI29Q	2-Chloro-1-(3-methylthiophen-2-yl)ethanone	Investigative	6539177	C7H7ClOS	174.65	CC1=C(SC=C1)C(=O)CCl	IC50 = 75000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BG40YF	3-Chloro-9-nitroso-carbazole	Investigative	46227261	C12H7ClN2O	230.65	C1=CC=C2C(=C1)C3=C(N2N=O)C=CC(=C3)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BG7CL8	4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide	Investigative	24959043	C24H24Cl2N6O	483.4	CN(C)CCNC(=O)C1=CC=C(C=C1)C2=CN=C3N2N=C(C=C3)NCC4=CC(=C(C=C4)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BGC3X2	3,6-Diamino-2-(4-chlorobenzoyl)-4-(2-iodophenyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	1729742	C21H12ClIN4OS	530.8	C1=CC=C(C(=C1)C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC=C(C=C4)Cl)N)N)C#N)I	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BGM0A4	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644436	C21H19Cl2F3N6O	499.3	C1=CC(=CC(=C1)OC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BGT30V	N-[3-[4-Oxo-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)-5H-thieno[3,2-c]pyridin-7-yl]phenyl]methanesulfonamide	Investigative	56660107	C21H16N4O3S2	436.5	CS(=O)(=O)NC1=CC=CC(=C1)C2=CNC(=O)C3=C2SC(=C3)C4=C5C=CNC5=NC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BGXS04	1-Bromo-4-(chloromethylsulfinyl)benzene	Investigative	11747156	C7H6BrClOS	253.54	C1=CC(=CC=C1S(=O)CCl)Br	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BH28DS	2-Chloro-1-(2,5-dimethylthiophen-3-yl)ethanone	Investigative	678545	C8H9ClOS	188.67	CC1=CC(=C(S1)C)C(=O)CCl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BHB48N	2-[4-[3-(Diaminomethylideneamino)benzoyl]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644426	C21H21ClN6O	408.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)C(=O)C3=CC(=CC=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BHNL58	2-(Furan-2-yl)-5-propan-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71450734	C16H17NO2S	287.4	CC(C)N1C(=O)CC(SC2=CC=CC=C21)C3=CC=CO3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BHT56X	5-(2-Fluorobenzyl)-2-phenyl-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one	Investigative	16010405	C22H18FNOS	363.4	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3F)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BI54WY	Chembl4283719	Investigative	145990133	C26H23N3O4S	473.5	C1CC1NC(=O)C2=CC=C(C=C2)C3CC(=O)N(C4=CC=CC=C4S3)CC5=CC=CC=C5[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BIAX49	1-(5-Bromothiophen-2-yl)-4-chlorobutan-1-one	Investigative	12867665	C8H8BrClOS	267.57	C1=C(SC(=C1)Br)C(=O)CCCCl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BIEC61	Pyrazolo[1,5-a]pyrimidine 9j	Investigative	23645572	C21H29N5O3S	431.6	CC(C)COC1=NC2=C(C=NN2C(=C1)NC3=CC=C(C=C3)S(=O)(=O)N(C)C)C(C)C	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BIF2G7	2-[3-[[4-(Diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride	Investigative	90644414	C15H19ClN6	318.8	C1=CC(=CC(=C1)N=C(N)N)CC2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BIHE76	Ethyl benzoate	Investigative	7165	C9H10O2	150.17	CCOC(=O)C1=CC=CC=C1	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BJ4X5W	Thiadiazolidinone (TDZD) deriv. 26	Investigative	9604909	C13H16N4O2S	292.36	CCNC(=O)/N=C\\1/N(C(=O)N(S1)CC)C2=CC=CC=C2	IC50 = 75000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BJD3S9	N-(6-(4-Ethylphenyl)-1H-indazol-3-yl)butyramide	Investigative	10040883	C19H21N3O	307.4	CCCC(=O)NC1=NNC2=C1C=CC(=C2)C3=CC=C(C=C3)CC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BK2GQ1	N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide	Investigative	27666048	C21H20N2O3S	380.5	CN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BK7XE1	Naringin	Investigative	442428	C27H32O14	580.5	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O	IC50 = 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BK9DW1	2-Ethyl-5-imino-4-phenyl-1,2,4-thiadiazolidin-3-one	Investigative	6539154	C10H11N3OS	221.28	CCN1C(=O)N(C(=N)S1)C2=CC=CC=C2	IC50 = 65000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BKQ03H	Pyrazolo[1,5-a]pyrimidine 9g	Investigative	23645569	C27H41N7O2S	527.7	CCN(CC)C1CCC(CC1)NC2=NC3=C(C=NN3C(=C2)NC4=CC=C(C=C4)S(=O)(=O)N(C)C)C(C)C	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BL2A9W	5-[[4-[[[5-(6-Methoxypyridin-3-yl)-1H-indazole-3-carbonyl]amino]methyl]piperidin-1-yl]methyl]furan-2-carboxylic acid	Investigative	89767395	C26H27N5O5	489.5	COC1=NC=C(C=C1)C2=CC3=C(C=C2)NN=C3C(=O)NCC4CCN(CC4)CC5=CC=C(O5)C(=O)O	IC50 = 70800 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BL83HR	4-Cyclohexyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione	Investigative	6539138	C9H14N2O2S	214.29	CN1C(=O)N(C(=O)S1)C2CCCCC2	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BL8O1M	2-Arylpurine deriv. 12	Investigative	23645300	C21H25N7O2	407.5	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(C=C3)C(=O)NCCC#N)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BLH2R5	N-[2-[2-(1H-Indol-3-yl)ethylamino]-2-oxoethyl]-2-phenyl-1H-pyrrolo[2,3-b]pyridine-5-carboxamide	Investigative	134143185	C26H23N5O2	437.5	C1=CC=C(C=C1)C2=CC3=CC(=CN=C3N2)C(=O)NCC(=O)NCCC4=CNC5=CC=CC=C54	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BLQN76	Pyrazolo[1,5-a]pyrimidine 9f	Investigative	23645568	C25H37N7O2S	499.7	CCNC1CCC(CC1)NC2=NC3=C(C=NN3C(=C2)NC4=CC=C(C=C4)S(=O)(=O)N(C)C)C(C)C	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BLV7U8	3-Methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine	Investigative	5384870	C13H11N3	209.25	CC1=CN=C2C=C(NC2=N1)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BM67QD	5,6-Dimethoxy-1-indanone	Investigative	75018	C11H12O3	192.21	COC1=C(C=C2C(=C1)CCC2=O)OC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BMP50R	6-(3,5-Dimethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine	Investigative	6538772	C14H13N3O2	255.27	COC1=CC(=CC(=C1)C2=CC3=NC=CN=C3N2)OC	IC50 = 60000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BN0T4H	5-Methyl-7-(4-morpholin-4-ylphenyl)-2-pyridin-4-ylthieno[3,2-c]pyridin-4-one	Investigative	56680583	C23H21N3O2S	403.5	CN1C=C(C2=C(C1=O)C=C(S2)C3=CC=NC=C3)C4=CC=C(C=C4)N5CCOCC5	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BN2IC3	4-Tert-Butyl-N-[2-Methyl-3-(6-{[4-(Morpholin-4-Ylcarbonyl)phenyl]amino}-7h-Purin-2-Yl)phenyl]benzamide	Investigative	53356518	C34H35N7O3	589.7	CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=NC4=C(C(=N3)NC5=CC=C(C=C5)C(=O)N6CCOCC6)NC=N4	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BN76DE	2-[[4-[[[5-(2,3-Difluorophenyl)-1H-indazole-3-carbonyl]amino]methyl]piperidin-1-yl]methyl]-1,3-oxazole-4-carboxylic acid	Investigative	89767636	C25H23F2N5O4	495.5	C1CN(CCC1CNC(=O)C2=NNC3=C2C=C(C=C3)C4=C(C(=CC=C4)F)F)CC5=NC(=CO5)C(=O)O	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BN9W7H	Chembl4204332	Investigative	145977815	C16H13NO4	283.28	CN1C2=CC3=C(C=C2OC(C1=O)C4=CC=CC=C4)OCO3	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BNDS51	Chembl4204473	Investigative	145975825	C26H21NO2	379.4	CC1=CC=C(C=C1)CN2C3=CC=CC=C3OC(C2=O)C4=CC=CC5=CC=CC=C54	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BNW83P	1-(4-Methoxyphenyl)furo[2,3-e]pyrrolo [1,2-a]pyrazin-5(4H)-one	Investigative	25268557	C16H12N2O3	280.28	COC1=CC=C(C=C1)C2=COC3=C2N4C=CC=C4C(=O)N3	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BO31FR	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)benzoyl]phenyl]guanidine;hydrochloride	Investigative	90644438	C22H19Cl2F3N6O	511.3	C1=CC(=CC(=C1)N=C(N)N)C(=O)C2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BO41JT	4-Bromophenacylamine hydrochloride	Investigative	2798216	C8H9BrClNO	250.52	C1=CC(=CC=C1C(=O)CN)Br.Cl	IC50 = 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BO5UY4	2-(4,5-Dichlorothiophen-3-yl)-2-oxoethyl acetate	Investigative	46227239	C8H6Cl2O3S	253.1	CC(=O)OCC(=O)C1=CSC(=C1Cl)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BOGE79	[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenyl]-[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]methanone;hydrochloride	Investigative	90644420	C19H21ClN6O	384.9	C1CN=C(N1)NC2=CC=C(C=C2)C(=O)C3=CC(=CC=C3)NC4=NCCN4.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BP02BV	5-Benzyl-2-(2-furyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one	Investigative	20878299	C20H17NO2S	335.4	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3)C4=CC=CO4	IC50 = 77200 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BPO9D8	4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-(2-pyrrolidin-1-ylethyl)benzamide	Investigative	49864785	C26H26Cl2N6O	509.4	C1CCN(C1)CCNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=C(C=C5)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BPR0M1	3,6-Diamino-2-benzoyl-4-(2-methoxyphenyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	51347384	C22H16N4O2S	400.5	COC1=CC=CC=C1C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC=CC=C4)N)N)C#N	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BQ1AM8	(4S,6E,12E)-18-Hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione	Investigative	49842666	C19H22O5	330.4	C[C@H]1C/C=C/C(=O)CCC/C=C/C2=C(C(=CC(=C2)OC)O)C(=O)O1	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BQ67SO	Chembl4294709	Investigative	145993560	C31H27N3O3S	521.6	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3C(=O)N)C4=CC=C(C=C4)C(=O)NCC5=CC=CC=C5	IC50 = 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BQUZ09	4-[6-[(3-Chlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide	Investigative	49865153	C25H25ClN6O	461	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=CC=C5)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BQX29W	Chembl4211676	Investigative	145966694	C25H18N2O4	410.4	C1=CC=C2C(=C1)C=CC=C2C3C(=O)N(C4=CC=CC=C4O3)CC5=CC=C(C=C5)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BR40CJ	Chembl4290490	Investigative	145988014	C24H20N2O5S	448.5	COC(=O)C1=CC=CC=C1C2CC(=O)N(C3=CC=CC=C3S2)CC4=CC=CC=C4[N+](=O)[O-]	IC50 = 80000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BRVO09	2-[4-Chloro-3-(trifluoromethyl)phenyl]-1-[3-[4-(diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644401	C21H19Cl2F3N6O	499.3	C1=CC(=CC(=C1)OC2=CC=C(C=C2)N=C(N)N)NC(=NC3=CC(=C(C=C3)Cl)C(F)(F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BRXS26	2-[(4-Oxo-2-phenyl-2,3-dihydro-1,5-benzothiazepin-5-yl)methyl]benzonitrile	Investigative	71578240	C23H18N2OS	370.5	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3C#N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BS1JE8	Chembl4207131	Investigative	145978604	C23H22N2O2	358.4	CCN(CC)C(=O)OC1=C(C2=CC=CC=C2N1)C3=CC=CC4=CC=CC=C43	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BS1NV6	1-Chloro-4-(2-chloro-1-sulfinylethyl)benzene	Investigative	127039929	C8H6Cl2OS	221.1	C1=CC(=CC=C1C(=S=O)CCl)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BS5HY8	2-Arylpurine deriv. 13	Investigative	23645301	C19H24N6O3	384.4	CC(C)N1C=NC2=C(N=C(N=C21)C3=CC=C(C=C3)NC(=O)OC)NCCOC	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BS5L1A	N-[3-[3-Methyl-4-(3-methylphenyl)piperazin-1-yl]propyl]-3-pyridin-4-yl-1,2,4-oxadiazole-5-carboxamide	Investigative	44448518	C23H28N6O2	420.5	CC1CN(CCN1C2=CC=CC(=C2)C)CCCNC(=O)C3=NC(=NO3)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BS5Z2V	5-(4-Chloro-5-methoxypyridin-2-yl)-N-(pyridin-4-ylmethyl)-1,3-oxazole-4-carboxamide	Investigative	57391300	C16H13ClN4O3	344.75	COC1=CN=C(C=C1Cl)C2=C(N=CO2)C(=O)NCC3=CC=NC=C3	IC50 = 63095.73 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BS84NK	1-(4-Methylphenyl)furo[2,3-e]pyrrolo[1,2-a] pyrazin-5(4H)-one	Investigative	25268556	C16H12N2O2	264.28	CC1=CC=C(C=C1)C2=COC3=C2N4C=CC=C4C(=O)N3	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BSDY31	1-(4-Bromophenyl)furo[2,3-e]pyrrolo[1,2-a] pyrazin-5(4H)-one	Investigative	25268199	C15H9BrN2O2	329.15	C1=CN2C(=C1)C(=O)NC3=C2C(=CO3)C4=CC=C(C=C4)Br	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BSXG90	1-(5-Acetyl-thiophen-2-yl)-2-chloro-ethanone	Investigative	4165708	C8H7ClO2S	202.66	CC(=O)C1=CC=C(S1)C(=O)CCl	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BSZK98	2-[3-[4-(Diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644410	C14H17ClN6O	320.78	C1=CC(=CC(=C1)OC2=CC=C(C=C2)N=C(N)N)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BT87AB	5-Ethyl-2-thiophen-2-yl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71457866	C15H15NOS2	289.4	CCN1C(=O)CC(SC2=CC=CC=C21)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BT8R9G	2-[2-(4-Bromophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione	Investigative	280603	C16H10BrNO3	344.16	C1=CC=C2C(=C1)C(=O)N(C2=O)CC(=O)C3=CC=C(C=C3)Br	IC50 = 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BT9VH6	6-(2,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	Investigative	70789255	C14H20N6	272.35	C1CC2(CCN(CC2)C3=NC=NC4=C3NC=N4)CNC1	IC50 = 55000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BTGQ54	Thiophene-2-carbaldehyde	Investigative	7364	C5H4OS	112.15	C1=CSC(=C1)C=O	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BTLQ36	Chembl4280203	Investigative	145980118	C29H24N4O4S	524.6	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3[N+](=O)[O-])C4=CC=C(C=C4)C(=O)NCC5=CC=CC=N5	IC50 = 75000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BTQ9D6	2-Phenyl-5-(p-methoxybenzyl)-2,3-dihydro-1,5-benzothiazepine-4(5H)-one	Investigative	71578311	C23H21NO2S	375.5	COC1=CC=C(C=C1)CN2C(=O)CC(SC3=CC=CC=C32)C4=CC=CC=C4	IC50 = 73700 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BTYW65	2-[4-(2-Bromoacetyl)phenyl]indene-1,3-dione	Investigative	127039586	C17H11BrO3	343.2	C1=CC=C2C(=C1)C(=O)C(C2=O)C3=CC=C(C=C3)C(=O)CBr	IC50 = 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BU23VG	2-(4-Fluorophenyl)-5-[(2-nitrophenyl)methyl]-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	71578378	C22H17FN2O3S	408.4	C1C(SC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3[N+](=O)[O-])C4=CC=C(C=C4)F	IC50 = 81500 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BU92AI	2-Chloro-1-(5-methylthiophen-2-yl)ethanone	Investigative	4962248	C7H7ClOS	174.65	CC1=CC=C(S1)C(=O)CCl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BUA86G	2-[4-(2-Hydroxypropan-2-yl)anilino]-3H-benzimidazole-5-carbonitrile	Investigative	70693142	C17H16N4O	292.33	CC(C)(C1=CC=C(C=C1)NC2=NC3=C(N2)C=C(C=C3)C#N)O	IC50 = 60000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BUH93Y	N-(5-Bromo-6-chloro-1H-indazol-3-yl)butanamide	Investigative	10087157	C11H11BrClN3O	316.58	CCCC(=O)NC1=NNC2=CC(=C(C=C21)Br)Cl	IC50 = 55000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BULG41	4-{5-[(4-Iodobenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}pyridine	Investigative	6539733	C14H10IN3OS	395.22	C1=CC(=CC=C1CSC2=NN=C(O2)C3=CC=NC=C3)I	IC50 = 198000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BUOE04	N-[4-[[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenyl]methyl]phenyl]-4,5-dihydro-1H-imidazol-2-amine;hydrochloride	Investigative	90644422	C19H23ClN6	370.9	C1CN=C(N1)NC2=CC=C(C=C2)CC3=CC(=CC=C3)NC4=NCCN4.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BUQE96	6-(3,4,5-Trimethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine	Investigative	6538773	C15H15N3O3	285.3	COC1=CC(=CC(=C1OC)OC)C2=CC3=NC=CN=C3N2	IC50 = 85000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BV0T7K	4'-Chloroacetophenone	Investigative	7467	C8H7ClO	154.59	CC(=O)C1=CC=C(C=C1)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BV13TL	2-(4-Bromophenyl)-2-oxoethyl acetate	Investigative	343879	C10H9BrO3	257.079	CC(=O)OCC(=O)C1=CC=C(C=C1)Br	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BV2UG1	2-[3-[4-(Diaminomethylideneamino)anilino]phenyl]guanidine;hydrochloride	Investigative	90644416	C14H18ClN7	319.79	C1=CC(=CC(=C1)N=C(N)N)NC2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BV34OS	Pyrazolo[1,5-a]pyrimidine 9i	Investigative	23645571	C23H33N7O2S	471.6	CC(C)C1=C2N=C(C=C(N2N=C1)NC3=CC=C(C=C3)S(=O)(=O)N(C)C)NC4CCCC(C4)N	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BV4S3C	5-Benzyl-2,3-dihydro-1,5-benzothiazepin-4-one	Investigative	12629212	C16H15NOS	269.4	C1CSC2=CC=CC=C2N(C1=O)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BV7NW5	N-[2-[2-(1H-Indol-3-yl)ethylamino]-2-oxoethyl]-3-phenyl-1H-indole-5-carboxamide	Investigative	134132531	C27H24N4O2	436.5	C1=CC=C(C=C1)C2=CNC3=C2C=C(C=C3)C(=O)NCC(=O)NCCC4=CNC5=CC=CC=C54	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BVA51K	4,5-Dibromothiophene-2-carbaldehyde	Investigative	813164	C5H2Br2OS	269.94	C1=C(SC(=C1Br)Br)C=O	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BVDF78	(S)-4-(6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide	Investigative	46933384	C22H26N6O	390.5	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5CC5	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BVI90B	Chembl4276946	Investigative	134611886	C12H11Cl2N3O	284.14	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BVJ4Z2	(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine	Investigative	25199517	C20H22N4	318.4	C1CN(CCC1CN)C2=NC=CC(=N2)C3=CC4=CC=CC=C4C=C3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BVX93T	4-Methoxy-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one	Investigative	396080	C17H14N2O2	278.3	COC1=CC=CC2=C1NC(=O)CC3=C2NC4=CC=CC=C34	IC50 = 139958.73 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BW02UO	2-[4-[4-(Diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644409	C14H17ClN6O	320.78	C1=CC(=CC=C1N=C(N)N)OC2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BW06GB	1-(4-Bromophenyl)-2-phenylsulfanylethanone	Investigative	4224626	C14H11BrOS	307.21	C1=CC=C(C=C1)SCC(=O)C2=CC=C(C=C2)Br	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BW1OB0	Chembl4216653	Investigative	145973974	C25H18ClNO2	399.9	C1=CC=C2C(=C1)C=CC=C2C3C(=O)N(C4=CC=CC=C4O3)CC5=CC=C(C=C5)Cl	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BWG2Z0	2-(2-Furyl)-5-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one	Investigative	3242308	C14H13NO2S	259.329	CN1C(=O)CC(SC2=CC=CC=C21)C3=CC=CO3	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BWY3P1	4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide	Investigative	49864850	C25H24Cl2N6O	495.4	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=C(C=C5)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BX21DM	N-(5,6-Bis(4-hydroxyphenyl)-1H-indazol-3-yl)butyramide	Investigative	135848037	C23H21N3O3	387.4	CCCC(=O)NC1=NNC2=CC(=C(C=C21)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O	IC50 = 56000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BXK94F	2-[4-Chloro-3-(trifluoromethyl)phenyl]-1-[3-[[4-(diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride	Investigative	90644403	C22H21Cl2F3N6	497.3	C1=CC(=CC(=C1)NC(=NC2=CC(=C(C=C2)Cl)C(F)(F)F)N)CC3=CC=C(C=C3)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BXPD02	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)anilino]phenyl]guanidine;hydrochloride	Investigative	90644442	C21H20Cl2F3N7	498.3	C1=CC(=CC(=C1)N=C(N)N)NC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BXT90N	1-(6-Amino-9H-purin-9-yl)ethanone	Investigative	56662952	C7H7N5O	177.16	CC(=O)N1C=NC2=C(N=CN=C21)N	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BY0WS7	3-(3-Benzyloxy-4-methoxy-phenyl)-thieno[2,3-b]pyrrolizin-8-one	Investigative	12128595	C23H17NO3S	387.5	COC1=C(C=C(C=C1)C2=CSC3=C2N4C=CC=C4C3=O)OCC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BY0XB6	N''-(2-((2-Chlorophenyl)(imino)methyl)phenyl)-N''-phenylbenzohydrazide	Investigative	46227237	C26H20ClN3O	425.9	C1=CC=C(C=C1)C(=O)NN(C2=CC=CC=C2)C3=CC=CC=C3C(=N)C4=CC=CC=C4Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BY53FQ	1-(4-Fluorophenyl)furo[2,3-e]pyrrolo[1,2-a] pyrazin-5(4H)-one	Investigative	25268555	C15H9FN2O2	268.24	C1=CN2C(=C1)C(=O)NC3=C2C(=CO3)C4=CC=C(C=C4)F	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BYN54B	3-(3,4-Dimethoxyphenyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one	Investigative	11358339	C17H14N2O3	294.3	COC1=C(C=C(C=C1)C2=CNC3=C2N4C=CC=C4C3=O)OC	IC50 ~ 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BYQM45	2-[4-[[3-(Diaminomethylideneamino)phenyl]methyl]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644428	C21H23ClN6	394.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)CC3=CC(=CC=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BZ8LJ2	2-[4-[3-(Diaminomethylideneamino)phenoxy]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644424	C20H21ClN6O	396.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)OC3=CC=CC(=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	BZE97Y	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[[3-(diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride	Investigative	90644440	C22H21Cl2F3N6	497.3	C1=CC(=CC(=C1)N=C(N)N)CC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	D05AMQ	thiadiazolidinone (TDZD) deriv. 6	Investigative	6539137	C8H14N2O2S	202.28	CCCCN1C(=O)N(SC1=O)CC	IC50 = 70000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	D0G4GB	omega-chloroacetophenone	Investigative	10757	C8H7ClO	154.59	C1=CC=C(C=C1)C(=O)CCl	IC50 = 50000 nM	Poor binder
T70977	Glycogen synthase kinase-3 beta	D0H4VB	PMID24900428C14	Investigative	71461150	C21H20FN3O3	381.4	CC1=C(C=CC(=C1)F)OCC2=CC(=C(C=N2)OC)C3=CC4=C(N3)CCNC4=O	IC50 = 53300 nM	Poor binder