Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T17048 | Target Info | |||
| Target Name | DNA topoisomerase II alpha (TOP2A) | ||||
| Synonyms |
DNA topoisomerase II, alpha isozyme; DNA topoisomerase 2alpha; DNA topoisomerase 2-alpha
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| Target Type | Clinical trial Target | ||||
| Gene Name | TOP2A | ||||
| Biochemical Class | Topoisomerase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 78 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Etoposide
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Approved | Compound Info | ||
| Synonyms |
etoposide; 33419-42-0; VePesid; Toposar; trans-Etoposide; Lastet; (-)-Etoposide; Zuyeyidal; Etoposidum; Etoposido; Vepesid J; Eposin; Etoposidum [INN-Latin]; Etoposide (VP16); VP 16-213; VP 16 (pharmaceutical); Etoposido [INN-Spanish]; Etopophos (phosphate salt); VP-16-213; 4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside; VP 16213; UNII-6PLQ3CP4P3; NK 171; NSC 141540; CCRIS 2392; HSDB 6517; 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside); EINECS 251-509-1; NSC-141540; Eposide; Etopol; Etosid; Vepeside; Demethyl EpipodophyllotoxinEthylidine Glucoside; E0675; Demethyl-epiodophyllotoxin ethylidene glucoside; Epipodophyllotoxin VP-16213; Eposin (TN); Etopophos (TN); Trans-Etoposide; VePESID (TN); Vepesid (TN); DEMETHY-EPIPODOPHYLLOTOXIN, ETHYLIDENE GLUCOSIDE; VP-16 (TN); Demethylepipodophyllotoxin-beta-D-ethylideneglucoside; Etoposide (JP15/USP/INN); Etoposide [USAN:INN:BAN:JAN]; Eposin, Vepesid, VP-16, Toposar, Etoposide; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI); Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside; 4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethylepipodophyllotoxin ethylidene-beta-D-glucoside; 4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin; 4-Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
Merbarone
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Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
NSC-336628
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| Activity |
IC50 = 120000 nM
|
[2] | |||
| Compound Name |
Methyl 2'-(2-hydroxyphenyl)-(2,4'-bibenzoxazole)-4-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL111574; methyl 2'-(2-hydroxyphenyl)-[2,4'-bibenzo[d]oxazole]-4-carboxylate; [2,4'-Bibenzoxazole]-4-carboxylicacid, 2'-(2-hydroxyphenyl)-, methyl ester; (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxyphenyl)-, methyl ester; [2,4'-Bibenzoxazole]-4-carboxylic acid, 2'-(2-hydroxyphenyl)-, methyl ester; ACMC-20n661; SCHEMBL11979724; CTK4C6968; ZINC598610; BDBM50147399; J-008796; 2''-(2-Hydroxy-phenyl)-[2,4'']bibenzooxazolyl-4-carboxylic acid methyl ester; methyl 2-(2-(2-hydroxyphenyl)benzo[d]oxazol-4-yl)benzo[d]oxazole-4-carboxylate
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
Bis[2-[2-(6-chloro-8-oxo-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2(7),3,5,9(16),10,12-heptaen-14-yl)ethyl-methylamino]ethyl] butanedioate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL506257; BDBM50251125; Bis(2-((2-(7-chloro-6-oxo-6H-dibenzo[cd,g]indazol-2-yl)-ethyl)-methyl-amino)-ethyl) succinate
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| Activity |
IC50 = 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2beta,4beta,8-Trimethyl-11-fluoro-1,2,4,4abeta-tetrahydrospiro[3,10-dioxa-9,11b-diaza-3H-cyclopenta[b]phenanthrene-5(6H),5'(2'H)-pyrimidine]-2',4',6'(1'H,3'H)-trione
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Investigative | Compound Info | ||
| Synonyms |
BDBM159925; SCHEMBL2505861; CHEMBL3357980; BDBM159843; US9040528, 2(b); US9040528, 2; US9040528, 77
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| Activity |
IC50 = 50000 nM
|
[5] | |||
| Compound Name |
(2R,4S,6R)-6-((3R,3Ar,5aS,6S,7S,9bR)-6-(3-hydroxypropyl)-3a,6,9b-trimethyl-7-(prop-1-en-2-yl)-2,3,3a,4,5,5a,6,7,8,9b-decahydro-1H-cyclopenta[a]naphthalen-3-yl)-2-methylheptane-1,4-diol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL462848; BDBM50250883
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| Activity |
IC50 = 50400 nM
|
[6] | |||
| Compound Name |
6-(4-Methylpiperazin-1-yl)-2-[2-(4-prop-2-ynoxyphenyl)-3H-benzimidazol-5-yl]-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3581009; SCHEMBL12888580; BDBM50498271; 6-(4-methylpiperazin-1-yl)-2'-(4-(prop-2-ynyloxy)phenyl)-1H,3'H-2,5'-bibenzo[d]imidazole
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| Activity |
IC50 = 51600 nM
|
[7] | |||
| Compound Name |
4-[3-(Tert-Butylamino)imidazo[1,2-a]pyridine-2-yl]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1914951; BDBM50357677
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| Activity |
IC50 = 52660 nM
|
[8] | |||
| Compound Name |
1H-[1,2,3]Triazolo[4,5-g]phthalazine-4,9-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL259990; SCHEMBL5404963; BDBM50376184; 2H-triazolo[4,5-g]phthalazine-4,9-dione; 1H-[1,2,3]triazolo[4,5-g]phthalazin-4,9-dione; 1H,4H,9H-[1,2,3]triazolo[4,5-g]phthalazine-4,9-dione
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| Activity |
IC50 = 52800 nM
|
[9] | |||
| Compound Name |
17-[3-(Dimethylamino)propoxy]-11,12-diazapentacyclo[11.8.0.02,10.04,9.014,19]henicosa-1,4,6,8,10,12,14(19),15,17,20-decaen-3-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4094285
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| Activity |
IC50 = 52890 nM
|
[10] | |||
| Compound Name |
2-Propan-2-yltriazolo[4,5-g]phthalazine-4,9-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL261342; BDBM50376174
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| Activity |
IC50 = 54500 nM
|
[9] | |||
| Compound Name |
2-(Benzylthio)-4-(3-chlorobenzylthio)-1,3,5-triazine-6(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836470; BDBM50354232
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| Activity |
IC50 = 54600 nM
|
[11] | |||
| Compound Name |
Chembl4226061
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Investigative | Compound Info | ||
| Synonyms |
BDBM50460519; J3.648.227C
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| Activity |
IC50 = 55300 nM
|
[12] | |||
| Compound Name |
N-Tert-butyl-2-(4-chlorophenyl)-6-phenylimidazo[1,2-a]pyridin-3-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3578326; BDBM50089640
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| Activity |
IC50 = 55370 nM
|
[13] | |||
| Compound Name |
3-Ethyltriazolo[4,5-g]phthalazine-4,9-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL406853; SCHEMBL5414299; BDBM50376181
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| Activity |
IC50 = 55600 nM
|
[9] | |||
| Compound Name |
2-Methyltriazolo[4,5-g]phthalazine-4,9-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL259989; SCHEMBL5410855; BDBM50376182
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| Activity |
IC50 = 55600 nM
|
[9] | |||
| Compound Name |
(5S)-5-[[Tert-butyl(dimethyl)silyl]oxymethyl]-4-[2-(3,4-dimethoxyphenyl)-1,3-dithian-2-yl]oxolan-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104323; BDBM50268187
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| Activity |
IC50 = 55700 nM
|
[14] | |||
| Compound Name |
2-Ethyltriazolo[4,5-g]phthalazine-4,9-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL261876; SCHEMBL5408576; BDBM50376180
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| Activity |
IC50 = 61500 nM
|
[9] | |||
| Compound Name |
(3E)-3-[(3,4,5-Trihydroxyphenyl)methylidene]-1-benzofuran-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL197216; BDBM50410153
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| Activity |
IC50 = 63000 nM
|
[15] | |||
| Compound Name |
3-(2-(Methylthio)thiazolo[5,4-b]quinolin-9-ylamino)phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL429930; BDBM50227947; 9-[[(3-hydroxy)phenyl]amino]-2-(methylthio)thiazolo[5,4-b]quinoline
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| Activity |
IC50 = 64340 nM
|
[16] | |||
| Compound Name |
1-[(2R,4S,5S)-4-[2-(3,4-Dimethoxyphenyl)-1,3-dithian-2-yl]-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4088260; BDBM50268185; 3'-[2-(3,4-Dimethoxyphenyl)-1,3-dithiane-2-yl]-3'-deoxythymidine
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| Activity |
IC50 = 64500 nM
|
[14] | |||
| Compound Name |
2-Butyltriazolo[4,5-g]phthalazine-4,9-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL260223; SCHEMBL5414286; BDBM50376176
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| Activity |
IC50 = 64800 nM
|
[9] | |||
| Compound Name |
(2R,6R)-Methyl 6-((3R,3aR,5aS,6S,7S,9bR)-6-(3-methoxy-3-oxopropyl)-3a,6,9b-trimethyl-7-(prop-1-en-2-yl)-2,3,3a,4,5,5a,6,7,8,9b-decahydro-1H-cyclopenta[a]naphthalen-3-yl)-2-methyl-4-oxoheptanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL464897; BDBM50250884; (9beta,25R)-23-Oxo-3,4-seco-5alpha-lanosta-4(28),7-diene-3,26-dioic acid dimethyl ester
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| Activity |
IC50 = 67300 nM
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[6] | |||
| Compound Name |
4H-1-Benzopyran-3-carboxaldehyde, 2-(methylphenylamino)-4-oxo-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3220041; CTK1D2391; DTXSID10465540; 2-(N-Methylanilino)-4-oxo-4H-1-benzopyran-3-carbaldehyde
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| Activity |
IC50 = 67860 nM
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[17] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(2-fluorophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836463; BDBM50354237
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| Activity |
IC50 = 72500 nM
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[11] | |||
| Compound Name |
Methyl 3-[(3R,3aR,5aS,6S,7S,9bR)-3a,6,9b-trimethyl-3-[(2R)-1-[(2R,4R)-4-methyl-5-oxooxolan-2-yl]propan-2-yl]-7-prop-1-en-2-yl-1,2,3,4,5,5a,7,8-octahydrocyclopenta[a]naphthalen-6-yl]propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL518106; DTXSID90348403; BDBM50250881; Methyl (23R,25R)-3,4-seco-9beta-H-lanosta-4(28),7-dien-26,23-olid-3-oate
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| Activity |
IC50 = 75700 nM
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[6] | |||
| Compound Name |
(E)-N-Methyl-2-(pyridin-2-ylmethylene)hydrazinecarbothioamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1765791; SCHEMBL13611503; NSC62321; ZINC4743611; BDBM50341545; NSC-62321; 2-Pyridinecarbaldehyde N-methylthiosemicarbazone #; (Z)-2-Pyridinecarbaldehyde 4-methylthiosemicarbazone; 2-Pyridinecarbaldehyde 4-methyl-3-thioxemicarbazone
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| Activity |
IC50 = 76000 nM
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[18] | |||
| Compound Name |
[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 7-[[2-[4-hydroxy-3-(hydroxymethyl)anilino]-2-oxoethyl]amino]-7-oxoheptanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435181; BDBM50493688
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| Activity |
IC50 = 78900 nM
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[19] | |||
| Compound Name |
4-Ethyl-1-(1-(2-pyridyl)ethylidene)-3-thiosemicarbazide
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Investigative | Compound Info | ||
| Synonyms |
NSC673732; CHEMBL507986; 2-Acetylpyridine N4(Ethyl)Thiosemicarbazone; KETONE, METHYL 2-PYRIDYL, 4-ETHYL-3-THIOSEMICARBAZIDE; Semicarbazide, 4-ethyl-1-(1-(2-pyridyl)ethylidene)-3-thio-; BRN 1533231; HapN(et)tsc; 3-ethyl-1-{[1-(pyridin-2-yl)ethylidene]amino}thiourea; BDBM50341550; NSC-673732; 2-acetylpyridine 4-ethyl-3-thiosemicarbazone; 1-(2-Pyridinyl)ethanone N-ethylthiosemicarbazone; Methyl 2-pyridyl ketone 4-ethyl-3-thiosemicarbazone; 1-ethyl-3-[(E)-1-(2-pyridyl)ethylideneamino]thiourea; (1E)-1-(2-Pyridinyl)ethanone N-ethylthiosemicarbazone #; Thiosemicarbazide, N(1)-ethyl-N(4)-[1-pyridylethylidene]-; (E)-N-Ethyl-2-(1-(pyridin-2-yl)ethylidene)hydrazinecarbothioamide
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| Activity |
IC50 = 79000 nM
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[18] | |||
| Compound Name |
6-Phenethylsulfanyl-7H-purin-2-amine
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Investigative | Compound Info | ||
| Synonyms |
NSC35866; 6-(2-phenylethylsulfanyl)-7H-purin-2-amine; CHEMBL1437990; NSC-35866; 6-(2-Phenylethylsulfanyl)-7~{h}-Purin-2-Amine; NCI60_003252; NCIMech_000318; NCIStruc1_000418; NCIStruc2_000499; SCHEMBL13742763; CTK3I7050; DTXSID20359128; ZINC540407; AU 135; BDBM50035880; CCG-35495; CCG-38133; NCGC00013415; 6-(Phenethylthio)-7H-purin-2-amine; Purine, 2-amino-6-(phenethylthio)-; Purine, 2-amino-6-(phenylethylthio)-; NCGC00013415-02; NCGC00096530-01; 6-((2-phenylethyl)thio)-9H-purin-2-amine; 1H-Purin-2-amine, 6-[(2-phenylethyl)thio]-
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| Activity |
IC50 = 85000 nM
|
[20] | |||
| Compound Name |
5-[2-(Diethylamino)ethyl]quinolino[4,3-b]quinoxalin-6-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884650; BDBM50208200
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| Activity |
IC50 = 87580 nM
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[21] | |||
| Compound Name |
1-[(2S,4S,5S)-5-[[Tert-butyl(dimethyl)silyl]oxymethyl]-4-[(3,4-dimethoxyphenyl)methyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4081883; BDBM50268189
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| Activity |
IC50 = 89200 nM
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[14] | |||
| Compound Name |
4-Methyl-1-(1-(2-pyridyl)ethylidene)-3-thiosemicarbazide
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Investigative | Compound Info | ||
| Synonyms |
Hapmtsc; CHEMBL446813; 2-acetylpyridine-N(4)-methyl-thiosemicarbazone; 1-methyl-3-[(E)-1-(2-pyridyl)ethylideneamino]thiourea; 1-methyl-3-[(E)-1-pyridin-2-ylethylideneamino]thiourea; NSC 293870; 2-Acetylpyridine-4-methyl-3-thiosemicarbazone; NSC293870; Semicarbazide, 4-methyl-1-(1-(2-pyridyl)ethylidene)-3-thio-; 3-methyl-1-{[1-(pyridin-2-yl)ethylidene]amino}thiourea; SCHEMBL17987719; KETONE, METHYL 2-PYRIDYL, 4-METHYL-3-THIOSEMICARBAZONE; BDBM50341549; NSC-293870; 2-acetylpyridine 4-methyl-3-thiosemicarbazone; (e)-2-acetylpyridine 4-methyl-thiosemicarbazone; (1E)-1-(2-Pyridinyl)ethanone N-methylthiosemicarbazone; N-methyl-2-(1-(pyridin-2-yl)ethylidene)hydrazinecarbothioamide; (E)-N-Methyl-2-(1-(pyridin-2-yl)ethylidene)hydrazinecarbothioamide; Hydrazinecarbothioamide, N-methyl-2-[1-(2-pyridinyl)ethylidene]-
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| Activity |
IC50 = 92000 nM
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[18] | |||
| Compound Name |
1-Ethyl-3-[(E)-2-pyridylmethyleneamino]thiourea
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Investigative | Compound Info | ||
| Synonyms |
NSC673832; CHEMBL1765792; SCHEMBL5180987; BDBM50341546; NSC-673832; 2-Pyridinecarbaldehyde N-ethylthiosemicarbazone; (E)-N-Ethyl-2-(pyridin-2-ylmethylene)hydrazinecarbothioamide
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| Activity |
IC50 = 94000 nM
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[18] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(2-chlorophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836469; BDBM50354234
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| Activity |
IC50 = 94100 nM
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[11] | |||
| Compound Name |
1-[(2R,4S,5S)-5-[[Tert-butyl(dimethyl)silyl]oxymethyl]-4-[(3,4-dimethoxyphenyl)methyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4061636; BDBM50268172
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| Activity |
IC50 = 99100 nM
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[14] | |||
| Compound Name |
2-Pyridinecarbaldehyde N-isopropylthiosemicarbazone #
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1765793; BDBM50341547; 2-Pyridinecarbaldehyde 4-isopropyl-3-thiosemicarbazone; (E)-N-Isopropyl-2-(pyridin-2-ylmethylene)hydrazinecarbothioamide
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| Activity |
IC50 ~ 100000 nM
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[18] | |||
| Compound Name |
5-Amino-7-[2-(diethylamino)ethylimino]-1,3,6-triphenylpyrimido[4,5-d]pyrimidine-2,4-dithione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2440361; BDBM50493844
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| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
N-(2-Morpholin-4-ylethyl)quinolino[4,3-b]quinoxalin-6-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883595; BDBM50208193
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| Activity |
IC50 = 100000 nM
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[21] | |||
| Compound Name |
4-Allyl-1-(1-(2-pyridyl)ethylidene)-3-thio-semicarbazide
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Investigative | Compound Info | ||
| Synonyms |
MLS000564161; CHEMBL455284; SMR000151711; 2-acetylpyridine 4-allyl-3-thiosemicarbazone; KETONE, METHYL 2-PYRIDYL, 4-ALLYL-3-THIOSEMICARBAZONE; Semicarbazide, 4-allyl-1-(1-(2-pyrydyl)ethylidene)-3-thio-; BRN 1466176; NSC318804; SCHEMBL21994255; BDBM57228; cid_3005984; NSC-318804; NCGC00246060-01; 1-(2-Pyridyl)ethanone 4-allylthiosemicarbazone; 1-allyl-3-[1-(2-pyridyl)ethylideneamino]thiourea; SR-01000040387; SR-01000040387-1; BRD-K47037663-001-01-8; (1E)-1-(2-Pyridinyl)ethanone N-allylthiosemicarbazone; 1-allyl-3-[(E)-1-(2-pyridyl)ethylideneamino]thiourea; 1-prop-2-enyl-3-(1-pyridin-2-ylethylideneamino)thiourea; 1-prop-2-enyl-3-[1-(2-pyridinyl)ethylideneamino]thiourea; 1-prop-2-enyl-3-[(Z)-1-pyridin-2-ylethylideneamino]thiourea
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| Activity |
IC50 ~ 100000 nM
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[18] | |||
| Compound Name |
N',N'-Diethyl-N-quinolino[4,3-b]quinoxalin-6-ylethane-1,2-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883370; BDBM50208196
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
1-Methyl-3-[(E)-1-pyrazin-2-ylethylideneamino]thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL113086; 2-Acetylpyrazinen(4)-Methylthiosemicarbazone; BDBM50341555; 2-Acetylpyrazine 4-methylthiosemicarbazone; 4-(1-pyrazin-2-yl ethylene) N''-methyl thiosemicarbazone; (E)-N-Methyl-2-(1-(pyrazin-2-yl)ethylidene)hydrazinecarbothioamide; Hydrazinecarbothioamide, N-methyl-2-(1-pyrazinylethylidene)-, (2E)-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
7-{[2-(Dimethylamino)ethyl]amino}-5-imino-1,6-triphenyl-5,6-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dithione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2440360; BDBM50493840; NSC746683; NSC-746683
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
1,3-Dihydroxy-9H-xanthen-9-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,3-Dihydroxyxanthone; 1,3-dihydroxyxanthen-9-one; 1,3-Dihydroxy-xanthone; 9H-Xanthen-9-one,1,3-dihydroxy-; 9H-Xanthen-9-one, 1,3-dihydroxy-; CHEMBL388525; SCHEMBL2314333; CTK4I0432; DTXSID00192030; BDBM174832; HMS3468P10; ALBB-015550; ZINC6117594; 2276AE; MFCD00800670; STL466245; AKOS004938955; MCULE-6377421589; US9114126, MB1; NS-02897; D5344; R3833
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
2-Pyridinecarboxaldehyde thiosemicarbazone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Picoline-2-aldehyde thiosemicarbazone; CHEMBL25988; Pyridine-2-carboxaldehyde thiosemicarbazone; Beta-pyridine-2yl thiosemicarbazone; Hydrazinecarbothioamide, 2-(2-pyridinylmethylene)-; Picolinaldehyde, thiosemicarbazone; Pyridine-2-carboxaldehyde, thiosemicarbazone; [(E)-[(pyridin-2-yl)methylidene]amino]thiourea; 2-(pyridin-2-ylmethylene)hydrazinecarbothioamide; [(E)-pyridin-2-ylmethylideneamino]thiourea; NSC 729; WLN: T6NJ B1UNMYZUS; [(E)-(pyridin-2-ylmethylidene)amino]thiourea; [(Z)-pyridin-2-ylmethylideneamino]thiourea; SCHEMBL293101; (E)-2-(pyridin-2-ylmethylene)hydrazinecarbothioamide; NSC729; NSC-729; Picolinaldehyde monothiosemicarbazone; BDBM50341553; MFCD00160323; NSC144418; ZINC12360590; [(E)-2-pyridylmethyleneamino]thiourea; AKOS005109625; 2-Pyridinecarbaldehyde thiosemicarbazone; MS-7716; NE57965; NSC-144418; [(pyridin-2-ylmethylidene)amino]thiourea; 2-Pyridinecarbaldehyde thiosemicarbazone #; (Z)-2-Pyridinecarbaldehydethiosemicarbazone; CS-0110143; EN300-43946
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
2'-Phenyl-[2,4']bibenzooxazolyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL113081; BDBM50147401; 2''-Phenyl-[2,4'']bibenzooxazolyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
1-Benzyl-3-[(E)-2-pyridylmethyleneamino]thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC670969; CHEMBL1765796; SCHEMBL5182156; HMS1717B12; BDBM50341552; NSC-670969; NCGC00335063-01; 2-Pyridinecarbaldehyde N-benzylthiosemicarbazone; AB01327238-02; AB01327238-03; SR-01000057115; SR-01000057115-1; (E)-N-Benzyl-2-(pyridin-2-ylmethylene)hydrazinecarbothioamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
5-Amino-7-[3-(dimethylamino)propylimino]-1,3,6-triphenylpyrimido[4,5-d]pyrimidine-2,4-dithione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2443292; BDBM50493839
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
5H-Quinolino[4,3-b]quinoxalin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883996; BDBM50208211
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
5-Amino-1,3,6-triphenyl-7-(2-pyridin-2-ylethylimino)pyrimido[4,5-d]pyrimidine-2,4-dithione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2443299; BDBM50493836
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
6-[2-(Dimethylamino)ethyl]-3-methylpyridazino[4,3-c]quinolin-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884054; BDBM50208204
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
5-Amino-1,3,6-triphenyl-7-(2-pyridin-4-ylethylimino)pyrimido[4,5-d]pyrimidine-2,4-dithione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2443300; BDBM50493845
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
1-Pyrrolidinecarbothioic acid (2-pyridylmethylene) hydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1765795; 1-Pyrrolidinecarbothioic acid, (2-pyridylmethylene)hydrazide; BDBM50341551; 1-Pyrrolidinecarbothioic acid, (2-pyridinylmethylene)hydrazide; (E)-N''-(Pyridin-2-ylmethylene)pyrrolidine-1-carbothiohydrazide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
5-(2-Morpholin-4-ylethyl)quinolino[4,3-b]quinoxalin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3885393; BDBM50208206
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
3-[3-(Butylamino)-2-hydroxypropoxy]-1-hydroxyxanthen-9-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2436126; BDBM50261768
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[23] | |||
| Compound Name |
17-[2-(Dimethylamino)ethoxy]-11,12-diazapentacyclo[11.8.0.02,10.04,9.014,19]henicosa-1,4,6,8,10,12,14(19),15,17,20-decaen-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4082118
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-Pyridinecarbaldehyde 4-allyl(thiosemicarbazone)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1765794; BDBM50341548; 2-Pyridinecarbaldehyde N-allylthiosemicarbazone #; (E)-N-Allyl-2-(pyridin-2-ylmethylene)hydrazinecarbothioamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
5-[3-(Dimethylamino)propyl]quinolino[4,3-b]quinoxalin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883419; BDBM50208201
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
Indeno[1,2-c]cinnolin-11-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127717; BDBM50031046; ZINC27299991
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N'-Benzyl-N'-methyl-N-quinolino[4,3-b]quinoxalin-6-ylpentane-1,5-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883499; BDBM50208205
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
6-[3-(Dimethylamino)propyl]-3-methylpyridazino[4,3-c]quinolin-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883473; BDBM50208209
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
5-Imino-1,6-triphenyl-7-[(pyridin-2-ylmethyl)amino]-5,6-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dithione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2443296; BDBM50493843; NSC746682; NSC-746682
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
N,N-Diethyl-2-quinolino[4,3-b]quinoxalin-6-yloxyethanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883394; BDBM50208210
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
Bengacarboline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL257249; BDBM50372626
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N-[(5S,5As,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]-4-[3-(trifluoromethyl)diazirin-3-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL592862; BDBM50308985
Click to Show/Hide
|
||||
| Activity |
IC50 = 114000 nM
|
[25] | |||
| Compound Name |
(3E)-5-Hydroxy-3-[(3,4,5-trihydroxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL372661; BDBM50410165
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[15] | |||
| Compound Name |
Schembl21810443
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098224; BDBM50246438
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[2] | |||
| Compound Name |
4-Chloro-10,11-difluoro-5-nitro-14-oxo-8-oxa-1-azatetracyclo[7.7.1.02,7.013,17]heptadeca-2,4,6,9(17),10,12,15-heptaene-15-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079855; SCHEMBL19971559; BDBM50259213; chloro-difluoro-nitro-oxo-[?]carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[26] | |||
| Compound Name |
4-(2,4-Dihydroxy-6-pentylbenzoyl)oxy-2-hydroxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134419; BDBM50496617
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[27] | |||
| Compound Name |
(4S,5S)-5-[[Tert-butyl(dimethyl)silyl]oxymethyl]-4-[(3,4-dimethoxyphenyl)methyl]oxolan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4089751; BDBM50268188
Click to Show/Hide
|
||||
| Activity |
IC50 = 137000 nM
|
[14] | |||
| Compound Name |
{4-Amino-6-[(4-fluorophenyl)amino]-1,3,5-triazin-2-yl}methyl morpholine-4-carbodithioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1345545; MLS000588478; C15H17FN6OS2; ZINC2397316; BDBM50035856; STK138543; AKOS001699496; MCULE-8827541624; SMR000219862; ST50106408; SR-01000086558; SR-01000086558-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 139000 nM
|
[20] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(4-fluorophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836465; BDBM50354247
Click to Show/Hide
|
||||
| Activity |
IC50 = 146600 nM
|
[11] | |||
| Compound Name |
[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 7-[(2-anilino-2-oxoethyl)amino]-7-oxoheptanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435185; BDBM50493691
Click to Show/Hide
|
||||
| Activity |
IC50 = 149000 nM
|
[19] | |||
| Compound Name |
Schembl21810417
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4062530; BDBM50246426
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[2] | |||
| Compound Name |
4-[(4-Benzylsulfanyl-6-oxo-1H-1,3,5-triazin-2-yl)sulfanylmethyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836509; BDBM50354243
Click to Show/Hide
|
||||
| Activity |
IC50 = 153400 nM
|
[11] | |||
| Compound Name |
N2-(2-(Diethylamino)ethyl)-N9-phenylthiazolo[5,4-b]quinoline-2,9-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL256856; BDBM50227940
Click to Show/Hide
|
||||
| Activity |
IC50 = 168900 nM
|
[16] | |||
| Compound Name |
3'-(3,4-Dihydroxybenzyl)-3'-deoxythymidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4089711; BDBM50268186
Click to Show/Hide
|
||||
| Activity |
IC50 = 176000 nM
|
[14] | |||
| Compound Name |
Schembl21810455
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4100676; BDBM50246437
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[2] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 166 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Ciprofloxacin XR
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
ciprofloxacin; 85721-33-1; Ciprofloxacine; Ciprobay; Ciproxan; Ciprofloxacina; Ciprofloxacinum; Ciprofloxacino; Cipro IV; Ciproxina; Ciprinol; Bernoflox; Ciprodar; Cifloxin; Septicide; Bacquinor; Ciproquinol; Cipromycin; Ciprocinol; Cipro XR; Superocin; Ciprowin; Ciprolon; Ciproflox; Ciprecu; BAY q 3939; Spitacin; Quintor; Quinolid; Proflaxin; Probiox; Ipiflox; Zumaflox; Ciproxine; Ciprolin; Roxytal; Italnik; Fimoflox; Corsacin; Citopcin; Ciprogis; Rancif; Ciriax; Ciplus; Baflox; Loxan; Cilab; Cycin; Cixan; Unex; GW1843; Ciprofloxacin Hydrochloride; Ciprofloxacin intratympanic - Otonomy
Click to Show/Hide
|
||||
| Activity |
IC50 > 256000 nM
|
[28] | |||
| Compound Name |
Novobiocin
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Albamix; Albamycin; Cardelmycin; Cathocin; Cathomycin; Inamycin; NOV; Novobiocina; Novobiocine; Novobiocinum; Robiocina; Sirbiocina; Spheromycin; Stilbiocina; Streptonivicin; Crystallinic acid; Novobiocin sodium salt; PA 93; U 6391; Albamycin (TN); Antibiotic PA-93; Novo-R; Novobiocin [INN:BAN]; Novobiocina [INN-Spanish]; Novobiocine [INN-French]; Novobiocinum [INN-Latin]; Streptonivicin (*Sodium salt*); [(3R,4S,5R,6R)-5-hydroxy-6-[2-hydroxy-3-[[4-hydroxy-3-(3-methylbut-2-enyl)benzoyl]amino]-8-methyl-4-oxochromen-7-yl]oxy-3-methoxy-2,2-dimethyloxan-4-yl] carbamate; N-[7-[[3-O-(Aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-.beta.-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-butenyl); (3R,4S,5R,6R)-5-hydroxy-6-{[4-hydroxy-3-({[4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]carbonyl}amino)-8-methyl-2-oxo-2H-chromen-7-yl]oxy}-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate; (3r,4s,5r,6r)-5-hydroxy-6-[(2-hydroxy-3-{[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]amino}-8-methyl-4-oxo-4h-chromen-7-yl)oxy]-3-methoxy-2,2-dimethyltetrahydro-2h-pyran-4-yl carbamate(non-preferred name); 7-(3-(O-Carbamoyl)-4-(O-methyl)-5,5-dimethyl-alpha-L-lyxopyranosyloxy)-4-hydroxy-3-(4-hydroxy-3-(3-methyl-2-butenyl)benzamidol)-8-methylcumarin; 7-(Carbamoyltetrahydro-3-hydroxy-5-methoxy-6,6-dimethylpyran-2-yloxy)-4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamide)-8-methyl-2H-chromen-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 256000 nM
|
[28] | |||
| Compound Name |
Camptothecin
Click to Show/Hide
|
Phase 3 | Compound Info | ||
| Synonyms |
camptothecin; Camptothecine; 7689-03-4; (S)-(+)-Camptothecin; Campathecin; d-Camptothecin; (+)-Camptothecine; (+)-Camptothecin; 20(S)-Camptothecine; 21,22-Secocamptothecin-21-oic acid lactone; NSC94600; (S)-Camptothecin; Camptothecine (8CI); 20(S)-Camptothecin; Camptothecine (S,+); CHEMBL65; UNII-XT3Z54Z28A; MLS000766223; (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; XT3Z54Z28A; CHEBI:27656; VSJKWCGYPAHWDS-FQEVSTJZSA-N; Camptothecin, Camptotheca acuminata; NSC-94600; Camptothecin derivat
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[29] | |||
| Compound Name |
Spermidine
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Phase 3 | Compound Info | ||
| Synonyms |
Spermidin; UNII-U87FK77H25; BRN 1698591; AI3-26636; EINECS 204-689-0; CHEMBL19612; CHEBI:16610; ATHGHQPFGPMSJY-UHFFFAOYSA-N; U87FK77H25; MFCD00008229; Spermidine hydrochloride; NSC528399; 1pot; Aminopropylbutandiamine; N-(4-Aminobutyl)-1,3-diaminopropane; Spectrum_000005; Tocris-0959; ACMC-20ajn3; AC1L1AQB; Spectrum2_000874; Spectrum3_000977; Spectrum4_001101; Spectrum5_001561; Lopac-S-2501; Biomol-NT_000212; bmse000116; bmse000951; bmse000955; Spermidine 0.1 M solution; Lopac0_001047; SCHEMBL15618; BSPBio_002613; KBioGR_001542; KBioSS_000345; 4-04-00-01300 (Beilstein Handbook Reference); DivK1c_001007; SPBio_000947; Spermidine, > =99% (GC); Spermidine, analytical standard; BPBio1_001276; GTPL2390; DTXSID4036645; CTK3J1693; KBio1_001007; KBio2_000345; KBio2_002913; KBio2_005481; KBio3_001833; MolPort-001-761-230; NINDS_001007; HY-B1776; ZINC1532612; BDBM50009353; PA(34); N-(3-Aminopropyl)-4-aminobutylamine; AKOS006222987; CCG-205124; DB03566; MCULE-8096530192; RTR-003757; SDCCGMLS-0066822.P001; IDI1_001007; NCGC00015937-01; NCGC00015937-02; NCGC00015937-03; NCGC00015937-04; NCGC00015937-05; NCGC00024903-01; NCGC00024903-02; NCGC00024903-03; AJ-26792; AN-22947; LS-45643; M923; NCI60_004294; SC-69371; DB-026892; TR-003757; CS-0013804; FT-0629162; ST24048721; ST45025991; C00315; 124S209; SR0
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[23] | |||
| Compound Name |
SPERMINE
Click to Show/Hide
|
Terminated | Compound Info | ||
| Synonyms |
spermine; 71-44-3; neuridine; musculamine; gerontine; Spermin; 4,9-Diaza-1,12-dodecanediamine; Diaminopropyltetramethylenediamine; N,N'-Bis(3-aminopropyl)-1,4-butanediamine; Spermine, puriss; N,N'-Bis(3-aminopropyl)butane-1,4-diamine; 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-; 1,4-Bis(aminopropyl)butanediamine; 4,9-Diazadodecamethylenediamine; 4,9-Diazadodecane-1,12-diamine; N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine); UNII-2FZ7Y3VOQX; 1,4-Bis(aminopropyl) butanediamine; Spermine Derivative; 1,4-Diaminobutane, N,N'-bis
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[23] | |||
| Compound Name |
ginsenoside Rg3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(20S)-ginsenoside Rg3
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|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 7-[[2-(4-hydroxyanilino)-2-oxoethyl]amino]-7-oxoheptanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435184; BDBM50493687
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[19] | |||
| Compound Name |
10-O-[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 1-O-methyl decanedioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435180; BDBM50493690
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[19] | |||
| Compound Name |
24-Hydroxy-beta-amyrin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
olean-12-ene-3beta,24-diol; CHEMBL489551; 3beta,24-dihydroxyolean-12-ene; Olean-12-ene-3,24-diol; (3beta)-olean-12-ene-3,24-diol; 24-hydroxy- -amyrin; olean-12-en-3beta,24-diol; SCHEMBL1011332; Oleana-12-ene-3beta,24-diol; BDBM50260251; ZINC13983826; AKOS032961763; C19732; Q27131922
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
2-[4-[[2-[[7-[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-7-oxoheptanoyl]amino]acetyl]amino]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435182; BDBM50493689
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[19] | |||
| Compound Name |
N-[6-[[2-[(8R,9S,13S,14S,17R)-3,17-Dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]acetyl]amino]hexyl]-5,11-dimethyl-6H-pyrido[4,3-b]carbazole-9-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1627914; BDBM50369151
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[31] | |||
| Compound Name |
(5S)-4-[2-(3,4-Dimethoxyphenyl)-1,3-dithian-2-yl]-5-(hydroxymethyl)oxolan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4069708; BDBM50268173
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[14] | |||
| Compound Name |
3'-(3,4-Dimethoxybenzyl)-3'-deoxythymidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4086302; BDBM50268192
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[14] | |||
| Compound Name |
[2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl] 7-[[2-[4-(hydroxymethyl)anilino]-2-oxoethyl]amino]-7-oxoheptanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435183; BDBM50493692
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[19] | |||
| Compound Name |
2-[(8R,9S,13S,14S,17R)-3,17-Dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-N-[6-[[2-(5,11-dimethylpyrido[4,3-b]carbazol-6-yl)acetyl]amino]hexyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1628076; BDBM50369153
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[31] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(4-chlorophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836506; BDBM50354254
Click to Show/Hide
|
||||
| Activity |
IC50 = 219300 nM
|
[11] | |||
| Compound Name |
{4-Amino-6-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl morpholine-4-carbodithioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1505015; Oprea1_610047; MLS000677479; HMS1614F12; HMS2592J05; BDBM50035855; STK080778; STK846015; ZINC18157698; AKOS001672845; AKOS005626297; MCULE-3321765756; SMR000271650; ST50105487
Click to Show/Hide
|
||||
| Activity |
IC50 = 229000 nM
|
[20] | |||
| Compound Name |
4-Benzylsulfanyl-6-butylsulfanyl-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836513; BDBM50354248
Click to Show/Hide
|
||||
| Activity |
IC50 = 234700 nM
|
[11] | |||
| Compound Name |
(3E)-3-[(3,4-Dihydroxyphenyl)methylidene]-5-hydroxy-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195195; BDBM50410158
Click to Show/Hide
|
||||
| Activity |
IC50 = 240000 nM
|
[15] | |||
| Compound Name |
[(3R,4S,5R)-3,4-Dihydroxy-5-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-3-yl]oxyoxolan-3-yl]methyl acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929025; BDBM50359309
Click to Show/Hide
|
||||
| Activity |
IC50 = 240000 nM
|
[32] | |||
| Compound Name |
3-O-beta-6-Deoxy-D-glucopyranosyl cincholic acid28-O-beta-D-glucopyranosyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095350; BDBM50317555
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIId
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095025; BDBM50317516
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Quinovic acid 28-O-beta-D-glucopyranosyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095349; BDBM50317556
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIj
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095339; Aesculioside G15; BDBM50317513
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,10-dihydroxy-4a-(hydroxymethyl)-2,2,6a,6b,9,9,12a-heptamethyl-3-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4-yl] 2-methylbutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094680; BDBM50317502; 21-O-Angeloyl-22-O-(2-methylbutanoyl)-3beta,16alpha,28-trihydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Ginsenoside Re
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ginsenoside B2; Panaxoside RE; ginsenoside-Re; UNII-46F3R0BL3I; Chikusetsusaponin IVc; NSC 308877; 46F3R0BL3I; CHEMBL510095; MFCD00133369; EINECS 257-814-6; NSC-308877; (20S)-ginsenoside Re; SCHEMBL669738; CTK8F0918; HY-N0044; BDBM50378779; s3811; AKOS025310861; ZINC242620164; CCG-270589; CS-3838; DB14815; C08944; 286G596; A829010; Q27105064; UNII-3K198YD54P component PWAOOJDMFUQOKB-WCZZMFLVSA-N; Ginsenoside-Re from Panax ginseng (Korean ginseng) root, triterpenoid saponin
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
[(3R,4R,4Ar,5S,6R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,6,10-trihydroxy-4a-(hydroxymethyl)-2,2,6a,6b,9,9,12a-heptamethyl-3-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4-yl] 2-methylbutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094678; BDBM50317504; 21-O-Angeloyl-22-O-(2-methylbutanoyl)-3beta,15alpha,16alpha,28-tetrahydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
4-(2,4-Dihydroxybenzoyl)oxy-2-hydroxy-6-pentylbenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134418; BDBM50496609
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[27] | |||
| Compound Name |
Aesculioside IV-23E
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094674; BDBM50317508
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
20(S)-Ginsenoside Rg2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095005; BDBM50317543
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Gypenoside VIII
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-WB232T95AV; CHEMBL473659; WB232T95AV; GS-Rd; (20S)-ginsenoside Rd; (GS)-Rd; SCHEMBL669260; HMS3885A14; HY-N0043; BDBM50317539; s3931; AKOS037514671; ZINC253387933; CCG-270588; CS-3839; C20725; Q27136471
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Ginsenoside F2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095007; ginsenoside-F2; 20(S)-Ginsenoside F2; 20(S)-Ginsenoside-F2; Sg(S)-ginsenoside f2; (20S)-ginsenoside F2; 20-(S)-Ginsenoside F2; SCHEMBL17576511; DTXSID20432763; BDBM50317538; MFCD06410948; s9044; ZINC96095534; AKOS037514666; CCG-270474; AB0029015; HY-125848; CS-0009605; N1568; X1142; C20779; 025S494; Q-100717; Q27146699; 3beta,20-bis(beta-D-glucopyranosyloxy)dammar-24-en-12beta-ol
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-4,5,10-trihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095017; BDBM50317517; 21-O-Angeloy-3beta,16alpha,22alpha,24,28-pentahydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
2, 3-Dihydroxy-12-ursen-28-oic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1097033; BDBM50317549
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Eryngioside 94A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094692; BDBM50317520
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
20(R)-Ginsenoside Rg2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095006; BDBM50317542
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Quinovic acid 3-O-beta-D-glucoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL508407; BDBM50317554; C36H56O10; ZINC49899430; AKOS032962167; 3-o-beta-d-glucopyranosyl quinovic acid; W2593; 3beta-(beta-D-Glucopyranosyloxy)urs-12-ene-27,28-dioic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IV-23D1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094675; BDBM50317507
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIIf
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095026; BDBM50317515
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Eryngioside E
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095019; BDBM50317533
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Eryngiioside L
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094687; BDBM50317523
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
AesculiosideIV-23C1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094358; BDBM50317510
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Gypenoside XVII
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
GYPENOSIDE-XVII; Gynosaponin S; Ginsenoside XVII; CHEMBL504441; HMS3887K09; HY-N0553; MFCD10566703; s9207; AKOS027251125; ZINC253387973; CCG-270587; CS-4163; N2767; Y0100; C20736; Q27146716
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIIb
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094683; BDBM50317527
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
(1S,2R,4As,6aR,6bR,8aR,10S,12aR,12bR,14bS)-1,2,6b,9,9,12a-hexamethyl-10-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4a-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)carbonyl)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-6a-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL501302; Zygophyloside E; BDBM50317552; ZINC96171514; 3-O-beta-D-glucopyranosyl quinovic acid28-O-beta-D-glucopyranosyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Eryngioside F
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095018; BDBM50317530
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIk
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094689; Aesculioside G16; BDBM50317522
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIIa
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094690; BDBM50317521
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IVc
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094679; BDBM50317503
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
(1S,2R,4As,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-1,2,6b,9,9,12a-hexamethyl-4a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095352; BDBM50317551
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IVb
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094681; BDBM50317511
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Saniculasaponin III
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094686; BDBM50317524
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIf
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095340; Aesculioside G13; BDBM50317529
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIIe
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095027; BDBM50317514
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Ginsenoside F3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095004; Ginsenoside-F3; HY-N0600; BDBM50317544; ZINC95548971; AKOS027251121; CS-0009606; N2377; Y0088
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
21beta-O,22alpha-O-Diangeloylbarringtogenol C
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094676; BDBM50317506; 21,22-O-Diangeloyl-3beta,16alpha,28-trihydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
(1S,2R,4As,6aR,6aR,6bR,8aR,10S,12aR,14bS)-4a-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxycarbonyl-1,2,6b,9,9,12a-hexamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095353; BDBM50317550
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-5,10-dihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-4-(2-methylpropanoyloxy)-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094682; BDBM50317528; 21-O-Angeloyl-22-O-(2-methylbutanoyl)-3beta,16alpha,24,28-tetrahydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIa
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094691; Aesculioside G5; BDBM50317532
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Unii-W6V49A8fjq
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
W6V49A8FJQ; CHEMBL507688; HY-N0041; BDBM50317540; Ginsenoside Rb3, analytical standard; MFCD10566396; s9208; AKOS037514669; CCG-270634; CS-3831; NCGC00485982-01; Q27146709
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
11-Fluoro-10-(4-methylpiperazin-1-yl)-5-nitro-14-oxo-8-oxa-1-azatetracyclo[7.7.1.02,7.013,17]heptadeca-2(7),3,5,9(17),10,12,15-heptaene-15-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066307; SCHEMBL19971576; BDBM50259246; fluoro-(4-methylpiperazin-1-yl)-nitro-oxo-[?]carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[26] | |||
| Compound Name |
Ginsenoside-F5
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL583152; BDBM50378778
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IId
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095016; BDBM50317518
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
(20R)-Ginsenoside Rg3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
20(R)-ginsenoside Rg3; CHEMBL1095008; (R)Ginsenoside-Rg3; (20R)Ginsenoside Rg3; 20(R)-propanaxidiol; (R)-Ginsenoside Rg3; BDBM50317536; MFCD11045225; s9021; ZINC96085899; AKOS027251123; CCG-270473; X6589; Q27136474
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-5,10-dihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-4-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094673; BDBM50317509; 21,22-O-Diangeloy-3beta,16alpha,24,28-tetrahydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
alpha-Amyrin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Viminalol; alpha-Amyrenol; alpha-Amyrine; Urs-12-en-3beta-ol; UNII-30ZAG40J8N; 5alpha-urs-12-en-3beta-ol; (3beta)-urs-12-en-3-ol; 30ZAG40J8N; CHEMBL455357; MFCD00016754; alfa-Amyrin; A-amyrin with hplc; EINECS 211-352-1; NSC 114787; urs-12-ene-3beta-ol; SCHEMBL377781; alpha-Amyrin, analytical standard; (3.beta.)-Urs-12-en-3-ol; ZINC4097713; 6930AF; BDBM50241956; AKOS024319514; LMPR0106170001; (3?)?-Urs-?12-?en-?3-?ol; Urs-12-en-3-ol, (3beta)- (9CI); C08615; 638A959; Q2501558
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Lupeol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Fagarasterol; Clerodol; Monogynol B; farganasterol; Lupenol; beta-Viscol; Triterpene lupeol; Fagarsterol; UNII-O268W13H3O; Lup-20(29)-en-3b-ol; Lup-20(29)-en-3-ol, (3-beta)-; .beta.-Viscol; O268W13H3O; NSC90487; MFCD00017351; Lup-20(29)-en-3-ol, (3b)-; Lup-20(29)-en-3.beta.-ol; EINECS 208-889-9; NSC 90487; (3-beta)-Lup-20(29)-en-3-ol; Lup-20(29)-en-3-ol, (3beta)-; Lup-20(29)-en-3-ol, (3.beta.)-; Monogynol B (6CI); HSDB 7687; Lupeol, >=94%; Lupeol, analytical standard; 20(29)-Lupen-3beta-ol; SCHEMBL148518; CHEMBL289191; KS-00000KMW; 3beta-lup-20(29)-en-3-ol; HY-N0790; ZINC4081455; (3beta)-lup-20(29)-en-3-ol; BDBM50377927; NSC-90487; s3614; AKOS016008524; CCG-268968; CS-7563; DB12622; DS-3391; LMPR0106130001; Lup-20(29)-en-3beta-ol (8CI); Lup-20(29)-en-3-beta-ol (8CI); NCI60_042005; N1291; V0212; C08628; 545L471; Q409366; Q-100615
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIc
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095014; BDBM50317519
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Lupeol 3-acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1097034; BDBM50317548
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Damara-20(22), 24-dien-3, 6, 12-trine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1096728; SCHEMBL16701871; BDBM50317534
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IVa
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094677; BDBM50317505
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIg
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094688; Aesculioside G14; BDBM50317531
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside IIIc
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095341; BDBM50317512
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Eryngiioside J
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094685; BDBM50317525
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
2-Pentyl-4,6-dihydroxybenzoic acid 3-pentyl-5-hydroxyphenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134421; Decarboxyanziaic acid; BDBM50496614
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[27] | |||
| Compound Name |
Ginsenoside rb1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Gynosaponin C; ginsenoside-Rb1; Sanchinoside E1; Panax saponin E; Arasaponin E1; Pseudoginsenoside D; Gypenoside III; Panaxsaponin E; UNII-7413S0WMH6; (20S)-ginsenoside Rb1; CHEMBL501515; GRb 1; 7413S0WMH6; MFCD00133367; EINECS 255-532-8; C54H92O23; NSC 310103; GSRb1; GS-Rb1; 20(S)-ginsenoside Rb1; BIDD:ER0108; HMS3885O12; HY-N0039; BDBM50317541; s3924; AKOS025311537; CCG-270640; CS-3829; DB06749; AB0016710; N1620; C20713; 753G439; Q-100470; Ginsenoside Rb1, primary pharmaceutical reference standard; Ginsenoside Rb1, European Pharmacopoeia (EP) Reference Standard; Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root, triterpenoid saponin
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
Aesculioside III
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094684; BDBM50317526
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
3-O-alpha-L-Rhamnopyranosyl quinovic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095351; BDBM50317553
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[30] | |||
| Compound Name |
1-Ethyl-3-[5-(2-methylpyridin-4-yl)-8-[(6-methylpyridin-3-yl)amino]isoquinolin-3-yl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4101490; SCHEMBL2552482; BDBM50266342
Click to Show/Hide
|
||||
| Activity |
IC50 > 256000 nM
|
[28] | |||
| Compound Name |
Methyl N-[[3-(ethylcarbamoylamino)-5-(2-methylpyridin-4-yl)isoquinolin-8-yl]methyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4078126; SCHEMBL12815550; BDBM50266343
Click to Show/Hide
|
||||
| Activity |
IC50 > 256000 nM
|
[28] | |||
| Compound Name |
Prop-2-ynyl N-[[3-(ethylcarbamoylamino)-5-(2-methylpyridin-4-yl)isoquinolin-8-yl]methyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4061762; SCHEMBL12814984; BDBM50266344
Click to Show/Hide
|
||||
| Activity |
IC50 > 256000 nM
|
[28] | |||
| Compound Name |
1-Ethyl-3-(8-methyl-5-pyridin-4-ylisoquinolin-3-yl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4099715; SCHEMBL2550762; BDBM50266363
Click to Show/Hide
|
||||
| Activity |
IC50 > 256000 nM
|
[28] | |||
| Compound Name |
(E)-3-(3,4-Dihydroxybenzylidene)benzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195143; BDBM50410156
Click to Show/Hide
|
||||
| Activity |
IC50 = 272000 nM
|
[15] | |||
| Compound Name |
3-[(E)-4-Hydroxybenzylidene]benzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL371047; BDBM50410152
Click to Show/Hide
|
||||
| Activity |
IC50 = 327000 nM
|
[15] | |||
| Compound Name |
Kaempferol 3-O-alpha-L-arabinopyranosyl-7-O-alpha-L-rhamnopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929026; BDBM50359310; Q27137234; 3-(alpha-L-Arabinopyranosyloxy)-4',5-dihydroxy-7-(alpha-L-rhamnopyranosyloxy)flavone
Click to Show/Hide
|
||||
| Activity |
IC50 = 330000 nM
|
[32] | |||
| Compound Name |
2-N-(4-Fluorophenyl)-6-(2H-tetrazol-5-ylsulfanylmethyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361009; BDBM50035860
Click to Show/Hide
|
||||
| Activity |
IC50 = 337000 nM
|
[20] | |||
| Compound Name |
(3E)-3-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL372372; BDBM50410155
Click to Show/Hide
|
||||
| Activity |
IC50 = 351000 nM
|
[15] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(4-nitrophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836468; BDBM50354255
Click to Show/Hide
|
||||
| Activity |
IC50 = 358900 nM
|
[11] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(2-nitrophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836466; BDBM50354233
Click to Show/Hide
|
||||
| Activity |
IC50 = 376700 nM
|
[11] | |||
| Compound Name |
3-[(E)-4-Nitrobenzylidene]benzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL370969; BDBM50410154
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
(3E)-3-[(3-Hydroxy-4-methoxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL381195; BDBM50410160
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
(3E)-3-Benzylidene-5-hydroxy-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL381410; BDBM50410151
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
Ethyl 2-[4-[(E)-(2-oxo-1-benzofuran-3-ylidene)methyl]phenyl]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL193628; BDBM50410162
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
(3E)-5-Hydroxy-3-[(4-hydroxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL426092; BDBM50410159
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
(E)-3-Benzylidenebenzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191804; BDBM50410161; (3E)-3-benzylidene-1-benzofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
(3E)-3-[(4-Fluorophenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL364033; BDBM50410163
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
(3E)-3-[(4-Methoxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191658; BDBM50410157
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
3-[(E)-4-Hydroxybenzylidene]-6-hydroxybenzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195416; SCHEMBL15426107; BDBM50164888; 6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-3H-benzofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
(3E)-3-[(3-Hydroxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL194829; BDBM50410164
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[15] | |||
| Compound Name |
Bakuchicin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
furo[2,3-f]chromen-7-one; 7H-Furo(2,3-f)(1)benzopyran-7-one; UNII-79Z8P9F2HJ; 79Z8P9F2HJ; CHEMBL499847; 7H-FURO[2,3-F]CHROMEN-7-ONE; Coumarino-5,6-furan; Bakuchicin, analytical standard; DTXSID30196046; BDBM50259953; ZINC33903696; AKOS006330699
Click to Show/Hide
|
||||
| Activity |
IC50 = 404000 nM
|
[33] | |||
| Compound Name |
4-Benzylsulfanyl-6-(cyclopropylmethylsulfanyl)-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836516; BDBM50354249
Click to Show/Hide
|
||||
| Activity |
IC50 = 481000 nM
|
[11] | |||
| Compound Name |
6-Benzylsulfanyl-4-[(3-methoxyphenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836461; BDBM50354246
Click to Show/Hide
|
||||
| Activity |
IC50 = 485300 nM
|
[11] | |||
| Compound Name |
4-[(4-Benzylsulfanyl-6-oxo-1H-1,3,5-triazin-2-yl)sulfanylmethyl]-3-fluorobenzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836510; BDBM50354239
Click to Show/Hide
|
||||
| Activity |
IC50 = 485800 nM
|
[11] | |||
| Compound Name |
6-Benzylsulfanyl-4-[(3-nitrophenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836467; BDBM50354244
Click to Show/Hide
|
||||
| Activity |
IC50 = 488300 nM
|
[11] | |||
| Compound Name |
9-Amino-5,6-difluoro-3-oxo-3H-pyrido[3,2,1-kl]phenoxazine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2002459; NSC648059; Carboxylic acid der.; SCHEMBL19971567; CTK7D8578; BDBM50259212; amino-difluoro-oxo-[?]carboxylic acid; NSC-648059; NCI60_016663; 3H-Pyrido[3,1-kl]phenoxazine-2-carboxylic acid, 9-amino -5,6-difluoro-
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
(2,2-Dimethyl-4-oxo-5-pentyl-1,3-benzodioxin-7-yl) 2,4-dihydroxy-6-pentylbenzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134404; BDBM50496613; 2-Pentyl-4,6-dihydroxybenzoic acid 2,2-dimethyl-4-oxo-5-pentyl-4H-1,3-benzodioxin-7-yl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[27] | |||
| Compound Name |
2-[(4-Benzylsulfanyl-6-oxo-1H-1,3,5-triazin-2-yl)sulfanylmethyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836507; BDBM50354242
Click to Show/Hide
|
||||
| Activity |
IC50 = 522000 nM
|
[11] | |||
| Compound Name |
3-[(2-Benzylsulfanyl-6-oxo-1H-1,3,5-triazin-4-yl)sulfanylmethyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836508; BDBM50354238
Click to Show/Hide
|
||||
| Activity |
IC50 = 528000 nM
|
[11] | |||
| Compound Name |
3-[(2R,3S,4S)-3,4-Dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929194; BDBM50359315
Click to Show/Hide
|
||||
| Activity |
IC50 = 550000 nM
|
[32] | |||
| Compound Name |
Kaempferol 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929193; Kaempferol-3-O-beta-glucopyranosyl-7-O-alpha-rhamnopyranoside; Kaem-3-Glc-7-Rha; SCHEMBL9993267; Kampferol 3-glucoside 7-rhamnoside; Kaempferol-3-glucoside-7-rhamnoside; BDBM50359314; ZINC67902860; MCULE-2511510719; kaempferol 3-O-glucoside 7-O-rhamnoside; Q27137238; Kaempferol-3-O-beta-D-glucoside-7-O-alpha-L-rhamnoside; kaempferol 3-O- -D-glucopyranosyl-7-O- -L-rhamnopyranoside; kaempferol-3-O-beta-D-glucopyranoside-7-O-alpha-L-rhamnopyranoside; 4H-1-Benzopyran-4-one, 7-[(6-deoxy-; A-L-mannopyranosyl)oxy]-3-(; A-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 600000 nM
|
[32] | |||
| Compound Name |
6-Benzylsulfanyl-4-sulfanylidene-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836540; BDBM50104617
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4,6-Dichloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-1,3,5-triazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836527; BDBM50104610; AKOS009154326
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
6-({[5-(Pyridin-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}methyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361015; BDBM50035866; ZINC14123197; AKOS033402494; MCULE-7423079067; Z153031486
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
2-[[4-Chloro-6-[(4-methoxyphenyl)methylamino]-1,3,5-triazin-2-yl]-methylamino]ethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836536; BDBM50104567
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-((3-(1H-Imidazol-1-yl)propyl)amino)-6-methylpyrimidin-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361022; 2-{[3-(1H-imidazol-1-yl)propyl]amino}-6-methylpyrimidin-4-ol; BDBM50035875; STK506889; ZINC11991554; AKOS002337124; MCULE-1229910210; ST51063333; VU0612259-1; 2-[(3-imidazolylpropyl)amino]-6-methylpyrimidin-4-ol; F3358-0407
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
2-[2-[[4-Chloro-6-[(4-methoxyphenyl)methylamino]-1,3,5-triazin-2-yl]amino]phenyl]ethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594327; BDBM50104568
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-[(2-Methylpyridin-4-yl)methylamino]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361023; BDBM50035876
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
{4-Amino-6-[(4-fluorophenyl)amino]-1,3,5-triazin-2-yl}methyl 4-methylpiperazine-1-carbodithioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1451460; Oprea1_209795; MLS000677509; C16H20FN7S2; HMS2593O22; HMS3382A04; BDBM50035857; STK028200; STL150432; ZINC20058051; AKOS001698462; AKOS005750075; MCULE-7658672090; SMR000271671; ST50105493
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
2-[4-Chloro-6-[methyl(2-hydroxyethyl)amino]-1,3,5-triazine-2-ylamino]phenethyl alcohol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836535; BDBM50104566
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Benzylsulfanyl-6-(cyclobutylmethylsulfanyl)-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836517; BDBM50354240
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Benzylsulfanyl-6-propylsulfanyl-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836512; BDBM50354250
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
6-{[(1-Cyclopentyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-N2-(4-fluorophenyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361010; ZINC8075238; BDBM50035861; AKOS033205604; MCULE-1427475615; Z126254094
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
2-[(4-Benzylsulfanyl-6-oxo-2,5-dihydro-1H-1,3,5-triazin-2-yl)sulfanyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594325; BDBM50104570
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-N-(4-Fluorophenyl)-6-[(1-propylimidazol-2-yl)sulfanylmethyl]-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361014; BDBM50035865
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(4-methoxyphenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836462; BDBM50354241
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-(4,6-Dichloro-1,3,5-triazine-2-ylamino)phenethyl alcohol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MurF inhibitor (compound 59); CHEMBL1836530; BDBM119117
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-[(3,4-Dimethoxyphenyl)methylamino]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361026; BDBM50035879; AKOS009169907
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
Olivetolic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2,4-Dihydroxy-6-pentylbenzoic acid; Olivetolcarboxylic acid; Allazetolcarboxylic acid; benzoic acid, 2,4-dihydroxy-6-pentyl-; beta-Resorcyclic acid, 6-pentyl-; 6-pentyl-beta-resorcylic acid; CHEMBL3134414; 2,4-Bis(Oxidanyl)-6-Pentyl-Benzoic Acid; 2,4-dihydroxy-6-pentylbenzoate; SCHEMBL9909323; DTXSID20197688; BDBM50496608; ZINC13339595; 2,4-Dihydroxy-6-pentyl-benzoic acid; FT-0699723; beta-Resorcylic acid, 6-pentyl- (7CI,8CI); C20417; Benzoic acid, 2,4-dihydroxy-6-pentyl- (9CI); A1-00494; Q3604545
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[27] | |||
| Compound Name |
6-{[(5-Cyclopropyl-1,3,4-oxadiazol-2-yl)sulfanyl]methyl}-N2-(4-fluorophenyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361012; BDBM50035863; ZINC14242958; AKOS033402276; MCULE-6061304349; Z153013088
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
Dibenzyl (2R)-2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)amino]pentanedioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3593348; BDBM50104574
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Amino-2-[(2S)-1-morpholin-4-yl-1-oxopropan-2-yl]sulfanyl-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361021; BDBM50035874; ZINC20297535
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
6-Methyl-2-{[(2-methyl-4-pyridinyl)methyl]amino}nicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361024; BDBM50035877; ZINC32577659; MCULE-5607792828
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
4-Methyl-2-[(2Z)-2-(pyridin-4-ylmethylidene)hydrazinyl]-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361019; BDBM50035872; ZINC16283570
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
2-[2-[[4-(Benzylamino)-6-chloro-1,3,5-triazin-2-yl]amino]phenyl]ethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594326; BDBM50104569
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Benzylsulfanyl-2-phenylsulfanyl-2,5-dihydro-1H-1,3,5-triazin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594324; BDBM50104571
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
{4-Amino-6-[(4-fluorophenyl)amino]-1,3,5-triazin-2-yl}methyl cyclohexyl(methyl)carbamodithioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361008; C18H23FN6S2; ZINC5025019; BDBM50035858; STL361259; AKOS003771033; MCULE-4816432458
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
(2S)-2-[2-[4-Methoxy-6-[[(1S)-1-methyl-2-oxo-2-(benzyloxy)ethyl]amino]-1,3,5-triazine-2-ylamino]benzoylamino]propionic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3593350; BDBM50104572
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4,6-Dichloro-[1,3,5]triazin-2-yl-4-methoxy-benzyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836534; SCHEMBL2801822; 4,6-dichloro-N-[(4-methoxyphenyl)methyl]-1,3,5-triazin-2-amine; BDBM50104611; AKOS009154783; 2,4-dichloro-6-(4-methoxybenzylamino)-1,3,5-triazine; (4,6-dichloro-[1,3,5]triazin-2-yl)-(4-methoxy-benzyl)-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-[(4,6-Dimethoxy-1,3,5-triazin-2-yl)thio]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836520; BDBM50104607; AKOS012157665; 2-(4,6-Dimethoxy-1,3,5-triazine-2-ylthio)benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Benzylsulfanyl-6-[(2-methoxyphenyl)methylsulfanyl]-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836460; BDBM50354256
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
N-(2-Ethylphenyl)-2-amino-4,6-dichloro-1,3,5-triazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836529; SCHEMBL8973755; BDBM50104613; AKOS006136975; 4,6-dichloro-N-(2-ethylphenyl)-1,3,5-triazin-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-Fluoro-N-((4-(4-fluorophenyl)-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361017; ZINC4059210; BDBM50035870; AKOS024578542; MCULE-3618995743; SR-01000006429; SR-01000006429-1; F0475-0037; F2135-1017
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
(2S)-2-[(4,6-Diamino-1,3,5-triazin-2-yl)sulfanyl]-1-morpholin-4-ylpropan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3352903; ZINC8704366; BDBM50035867
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
{4-Amino-6-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl piperidine-1-carbodithioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1597544; Oprea1_617633; MLS000677692; HMS2609G20; BDBM50035859; STK032857; STL038921; ZINC18127018; AKOS001672844; AKOS005692447; MCULE-5484188237; SMR000271616; ST50105486
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
Methyl 2-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836526; 2-[O-Carbomethoxyanilino]-4,6-dichloro-S-triazine; BDBM50104616; Methyl 2-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzoate #
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
N-((4-(2-Chlorophenyl)-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-3-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361016; Oprea1_231432; ZINC4059271; BDBM50035869; AKOS024578607; MCULE-4154918838; F0475-0477
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
Propan-2-yl 2-[[4-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzoyl]amino]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3593347; BDBM50104609
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
6-[(Cyclopentylsulfanyl)methyl]-N2-(4-fluorophenyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361013; BDBM50035864; ZINC26245476; AKOS033786451; MCULE-9842107472; AB01001361-01; Z217753768
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
N-(2-Tert-butylphenyl)-4,6-dichloro-1,3,5-triazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836528; BDBM50104614; AKOS013582360
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Methyl-2-[(2Z)-2-(pyridin-3-ylmethylidene)hydrazinyl]-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361020; BDBM50035873; ZINC16512965
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
6-(4-Aminophenyl)-4-sulfanylidene-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594328; BDBM50104400
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-[(4,6-Dimethoxy-1,3,5-triazin-2-yl)amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836521; BDBM50104606; 2-(4,6-Dimethoxy-1,3,5-triazine-2-ylamino)benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-N-(4-Fluorophenyl)-6-[(1-methyltetrazol-5-yl)sulfanylmethyl]-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361011; BDBM50035862
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
Methyl 2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836524; SCHEMBL9384288; BDBM50104608; SR-01000385680; SR-01000385680-1; 2-(4,6-Dimethoxy-1,3,5-triazine-2-yloxy)benzoic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
Benzyl 4-[2,4-bis(phenylmethoxy)benzoyl]oxy-2-hydroxybenzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134417; BDBM50496615
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[27] | |||
| Compound Name |
2-[(2-Methylpyridin-4-yl)methylamino]-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361025; BDBM50035878
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
4-(2,4-Dihydroxybenzoyloxy)-2-hydroxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134420; SCHEMBL2281149; BDBM50496610
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[27] | |||
| Compound Name |
N-(2-Bromophenyl)-4,6-dichloro-1,3,5-triazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836531; N-(2-bromophenyl)-2-amino-4,6-dichloro-1,3,5-triazine; SCHEMBL8973097; CTK4G5072; DTXSID10275282; BDBM50104612; AKOS012164179; N-(o-Bromophenyl)-4,6-dichloro-s-triazine-2-amine; 1,3,5-Triazin-2-amine,N-(2-bromophenyl)-4,6-dichloro-
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Benzylsulfanyl-6-(cyclohexylmethylsulfanyl)-1H-1,3,5-triazin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836519; BDBM50354245
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
2-Pentyl-4-[2,4-bis(benzyloxy)-6-pentylbenzoyloxy]-6-hydroxybenzoic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134415; BDBM50496616
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[27] | |||
| Compound Name |
N-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-D-glutamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836522; BDBM50104575
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
4-Phenyl-6-thioxo-5,6-dihydro-1,3,5-triazin-2(1H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836537; AC1MDXVQ; CTK1B9094; DTXSID60384772; HMS1665I07; ZINC164570; BDBM50104322; AKOS024627968; CCG-250346; MCULE-6694389230; F2184-0190; 1,3,5-Triazin-2(1H)-one, 3,4-dihydro-6-phenyl-4-thioxo-; 4-Thioxo-6-phenyl-3,4-dihydro-1,3,5-triazine-2(1H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
Dibenzyl (2R)-2-[[2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)sulfanyl]benzoyl]amino]pentanedioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3593349; BDBM50104573
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Compound Name |
N-((4-Phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-2-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361018; ZINC4059237; BDBM50035871; AKOS024578576; MCULE-7305220004; SR-01000006438; SR-01000006438-1; F0475-0171
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
N-[[4-(3,4-Dichlorophenyl)-5-sulfanylidene-1H-1,2,4-triazol-3-yl]methyl]-3-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
TCMDC-123816; GNF-Pf-4873; CHEMBL579923; SJ000233075; Oprea1_833639; ZINC6235335; BDBM50035868; MCULE-8264600789; SR-01000442425; SR-01000442425-1
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[20] | |||
| Compound Name |
2-(4,6-Dichloro-1,3,5-triazine-2-ylthio)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836525; BDBM50104615
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[11] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Screening of triterpenoids isolated from Phyllanthus flexuosus for DNA topoisomerase inhibitory activity. J Nat Prod. 2001 Dec;64(12):1545-7. | ||||
| REF 2 | Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity. J Med Chem. 2018 Feb 8;61(3):1375-1379. | ||||
| REF 3 | Critical structural motif for the catalytic inhibition of human topoisomerase II by UK-1 and analogs. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3221-6. | ||||
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