Protein-Protein Interaction Details
| Protein General Information | Top | ||||
|---|---|---|---|---|---|
| Full Name | Mediator of RNA polymerase II transcription subunit 14 (MED14) | ||||
| UniProt ID | MED14_HUMAN | ||||
| Gene Name | MED14 | ||||
| Gene ID | 9282 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Estrogen receptor (ESR) | Target Info | PPI Info | [1] | |
| Estrogen receptor beta (ESR2) | Target Info | PPI Info | [2] | ||
| Vitamin D3 receptor (VDR) | Target Info | PPI Info | [3] | ||
| Interacting Clinical trial Target(s) | Cyclin-dependent kinase 8 (CDK8) | Target Info | PPI Info | [3] | |
| Interacting Literature-reported Target(s) | Hepatocyte nuclear factor 4-alpha (HNF4A) | Target Info | PPI Info | [4] | |
| Sterol regulatory element binding protein-1 (SREBF1) | Target Info | PPI Info | [5] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex. J Biol Chem. 2000 Jul 7;275(27):20928-34. | ||||
| REF 2 | Quantitative mapping of RNA-mediated nuclear estrogen receptor interactome in human breast cancer cells. Sci Data. 2018 Mar 6;5:180031. | ||||
| REF 3 | Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell. 1999 Mar;3(3):361-70. | ||||
| REF 4 | Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205. Mol Endocrinol. 2002 Jul;16(7):1502-10. | ||||
| REF 5 | Structure, function, and activator-induced conformations of the CRSP coactivator. Science. 2002 Feb 8;295(5557):1058-62. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.