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REF 1 |
Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205. Mol Endocrinol. 2002 Jul;16(7):1502-10.
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TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4. Mol Cell Biol. 2002 Aug;22(15):5626-37.
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Novel polymorphisms of nuclear receptor SHP associated with functional and structural changes. J Biol Chem. 2010 Aug 6;285(32):24871-81.
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Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression. Drug Metab Dispos. 2006 May;34(5):756-64.
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Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression. J Biol Chem. 2001 Nov 9;276(45):41690-9.
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Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol Cell Proteomics. 2005 Feb;4(2):205-13.
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Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription. Am J Physiol Gastrointest Liver Physiol. 2005 Jan;288(1):G74-84.
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Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity. Mol Endocrinol. 2002 Feb;16(2):402-10.
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Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c. Mol Endocrinol. 2007 Nov;21(11):2698-712.
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Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha. Mol Pharmacol. 2008 Sep;74(3):913-23.
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Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepat... J Biol Chem. 2004 Oct 22;279(43):45139-47.
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Activated sterol regulatory element-binding protein-2 suppresses hepatocyte nuclear factor-4-mediated Cyp3a11 expression in mouse liver. Mol Pharmacol. 2011 Jan;79(1):148-56.
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Functional association between CBP and HNF4 in trans-activation. Biochem Biophys Res Commun. 1997 Dec 29;241(3):664-9.
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Acetylation regulates transcription factor activity at multiple levels. Mol Cell. 2000 Apr;5(4):745-51.
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Transcriptional regulation of human eosinophil RNase2 by the liver-enriched hepatocyte nuclear factor 4. J Cell Biochem. 2009 Feb 1;106(2):317-26.
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Negative autoregulation of HNF-4alpha gene expression by HNF-4alpha1. Biochem J. 2005 May 15;388(Pt 1):325-32.
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Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription. J Biol Chem. 2002 Feb 15;277(7):5054-60.
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REF 19 |
Critical structural elements and multitarget protein interactions of the transcriptional activator AF-1 of hepatocyte nuclear factor 4. J Biol Chem. 1998 Nov 6;273(45):29950-7.
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Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis. Oncogene. 2003 Aug 28;22(36):5602-13.
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REF 21 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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