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| Protein General Information (TTD Target) |
Top |
| Full Name |
Pregnane X receptor (NR1I2)
|
Literature-reported
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Target Info
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| UniProt ID |
NR1I2_HUMAN
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| Gene Name |
NR1I2
|
| Gene ID |
8856
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Retinoic acid receptor RXR-beta (RXRB) |
Target Info
|
PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Hepatocyte nuclear factor 4-alpha (HNF4A) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Tumor suppressor protein p53 negatively regulates human pregnane X receptor activity. Mol Pharmacol. 2013 Jun;83(6):1229-36.
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| REF 2 |
Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription. Am J Physiol Gastrointest Liver Physiol. 2005 Jan;288(1):G74-84.
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