Protein-Protein Interaction Details
| Protein General Information | Top | ||||
|---|---|---|---|---|---|
| Full Name | Bcl-2-like protein 11 (BCL2L11) | ||||
| UniProt ID | B2L11_HUMAN | ||||
| Gene Name | BCL2L11 | ||||
| Gene ID | 10018 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Apoptosis regulator Bcl-2 (BCL-2) | Target Info | PPI Info | [1] | |
| Interacting Clinical trial Target(s) | Apoptosis regulator Bcl-W (BCL-W) | Target Info | PPI Info | [2] | |
| Apoptosis regulator Bcl-xL (BCL-xL) | Target Info | PPI Info | [3] | ||
| Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) | Target Info | PPI Info | [4] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 1998 Jan 15;17(2):384-95. | ||||
| REF 2 | Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell. 2006 May;9(5):351-65. | ||||
| REF 3 | Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells. Mol Cell Biol. 2005 Nov;25(22):10017-28. | ||||
| REF 4 | Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM. Cell Signal. 2010 May;22(5):801-8. | ||||
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