Protein-Protein Interaction Details
Protein General Information | Top | ||||
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Full Name | PP2A subunit A isoform PR65-alpha (PPP2R1A) | ||||
UniProt ID | 2AAA_HUMAN | ||||
Gene Name | PPP2R1A | ||||
Gene ID | 5518 |
Interacting TTD Target Information | Top | ||||
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Interacting Successful Target(s) | Estrogen receptor (ESR) | Target Info | PPI Info | [1] | |
Interacting Clinical trial Target(s) | Histone deacetylase 4 (HDAC4) | Target Info | PPI Info | [2] | |
Cellular tumor antigen p53 (TP53) | Target Info | PPI Info | [3] | ||
Serine/threonine PP2A-alpha (PPP2CA) | Target Info | PPI Info | [4] | ||
Interacting Patented-recorded Target(s) | Protein phosphatase methylesterase 1 (PME-1) | Target Info | PPI Info | [5] | |
Interacting Literature-reported Target(s) | PP2A B subunit isoform R5-alpha (PPP2R5A) | Target Info | PPI Info | [4] |
References | Top | ||||
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REF 1 | Liganded ER Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation. Mol Endocrinol. 2015 Nov;29(11):1646-57. | ||||
REF 2 | Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nat Med. 2012 May;18(5):783-90. | ||||
REF 3 | Identification of novel p53-binding proteins by biomolecular interaction analysis combined with tandem mass spectrometry. Mol Biotechnol. 2003 Mar;23(3):203-12. | ||||
REF 4 | A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Mol Cell Proteomics. 2009 Jan;8(1):157-71. | ||||
REF 5 | An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Mol Syst Biol. 2009;5:237. |
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