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Target General Information |
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Target ID |
T58307 |
Target Info
|
Target Name |
Protein phosphatase methylesterase 1 (PME-1) |
Synonyms |
PRO0750; PP2593; PME1 |
Target Type |
Patented-recorded Target |
Gene Name |
PPME1 |
Biochemical Class |
Carboxylic ester hydrolase |
UniProt ID |
|
Target Interacting Proteins |
Top |
Ester hydrolases |
[+] 3 Ester hydrolases |
+ |
Interacting Target Name |
Serine/threonine PP2A-alpha (PPP2CA) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; RP-C; Replication protein C; PP2A-alpha |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[1] |
2 |
Affinity Capture-MS |
[2] |
3 |
Affinity Capture-MS |
[3] |
4 |
Affinity Capture-Western |
[4] |
Interacting Protein Name |
PP2A subunit A isoform PR65-alpha (PPP2R1A) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
PP2A.Aalpha; PP2AAALPHA; PR65A |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[1] |
2 |
Affinity Capture-MS |
[4] |
3 |
Affinity Capture-Western |
[4] |
Interacting Protein Name |
Protein phosphatase 2 catalytic subunit beta (PPP2CB) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
PP2Abeta; PP2CB |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[1] |
2 |
Affinity Capture-MS |
[4] |
References |
Top |
REF 1 |
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Mol Syst Biol. 2009;5:237.
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REF 2 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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REF 3 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
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REF 4 |
Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data. Mol Cell Proteomics. 2015 Dec;14(12):3274-83.
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