| Target and Pathway |
Top |
| Target(s) |
Angiotensin-converting enzyme (ACE) |
Target Info
|
Inhibitor |
[1] |
| Bacterial Deoxyuridine triphosphate nucleotidohydrolase (Bact dut) |
Target Info
|
Inhibitor |
[1] |
| Bacterial Glucosamine-6-phosphate synthase (Bact glmS) |
Target Info
|
Inhibitor |
[1] |
| Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase (Bact folK) |
Target Info
|
Inhibitor |
[1] |
| Calmodulin (CALM) |
Target Info
|
Inhibitor |
[1] |
| Candida Mannose-6-phosphate isomerase (Candi PMI1) |
Target Info
|
Inhibitor |
[1] |
| Carbonic anhydrase II (CA-II) |
Target Info
|
Inhibitor |
[1] |
| Dihydrodiol dehydrogenase type I (AKR1C3) |
Target Info
|
Inhibitor |
[1] |
| Estrogen receptor beta (ESR2) |
Target Info
|
Inhibitor |
[1] |
| GABA transaminase (ABAT) |
Target Info
|
Inhibitor |
[1] |
| Hydroxyphenylpyruvate dioxygenase (HPD) |
Target Info
|
Inhibitor |
[1] |
| Leukotriene A-4 hydrolase (LTA4H) |
Target Info
|
Inhibitor |
[1] |
| Matrix metalloproteinase-12 (MMP-12) |
Target Info
|
Inhibitor |
[1] |
| Mycobacterium Biosynthetic alanine racemase (MycB alr) |
Target Info
|
Inhibitor |
[1] |
| Mycobacterium Thymidine monophosphate kinase (MycB tmk) |
Target Info
|
Inhibitor |
[1] |
| Nitric-oxide synthase brain (NOS1) |
Target Info
|
Inhibitor |
[1] |
| Nitric-oxide synthase endothelial (NOS3) |
Target Info
|
Inhibitor |
[1] |
| Pancreatic elastase 1 (CELA1) |
Target Info
|
Inhibitor |
[1] |
| Phospholipase A2 (PLA2G1B) |
Target Info
|
Inhibitor |
[1] |
| Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) |
Target Info
|
Inhibitor |
[1] |
| Plasmodium Hypoxanthine-guanine phosphoribosyltransferase (Malaria LACZ) |
Target Info
|
Inhibitor |
[1] |
| PTPN1 messenger RNA (PTPN1 mRNA) |
Target Info
|
Inhibitor |
[1] |
| Staphylococcus Beta-lactamase (Stap-coc blaZ) |
Target Info
|
Inhibitor |
[1] |
| Staphylococcus D-amino acid aminotransferase (Stap-coc dat) |
Target Info
|
Inhibitor |
[1] |
| Superoxide dismutase Cu-Zn (SOD Cu-Zn) |
Target Info
|
Inhibitor |
[1] |
| Thioredoxin (TXN) |
Target Info
|
Inhibitor |
[1] |
|
BioCyc
|
Reactive oxygen species degradation
|
|
GABA shunt
|
|
Valine degradation
|
|
Beta-alanine degradation
|
|
4-aminobutyrate degradation
|
|
Citrulline-nitric oxide cycle
|
|
Leukotriene biosynthesis
|
|
Superpathway of steroid hormone biosynthesis
|
|
Allopregnanolone biosynthesis
|
|
Androgen biosynthesis
|
|
Phospholipases
|
|
KEGG Pathway
|
Peroxisome
|
|
Amyotrophic lateral sclerosis (ALS)
|
|
Huntington's disease
|
|
Prion diseases
|
|
Alanine, aspartate and glutamate metabolism
|
|
Valine, leucine and isoleucine degradation
|
|
beta-Alanine metabolism
|
|
Propanoate metabolism
|
|
Butanoate metabolism
|
|
Metabolic pathways
|
|
GABAergic synapse
|
|
Renin-angiotensin system
|
|
Chagas disease (American trypanosomiasis)
|
|
Hypertrophic cardiomyopathy (HCM)
|
|
Adherens junction
|
|
Insulin signaling pathway
|
|
Arginine and proline metabolism
|
|
Calcium signaling pathway
|
|
Phagosome
|
|
Circadian entrainment
|
|
Long-term depression
|
|
Salivary secretion
|
|
Alzheimer's disease
|
|
Pyrimidine metabolism
|
|
Purine metabolism
|
|
Drug metabolism - other enzymes
|
|
cGMP-PKG signaling pathway
|
|
HIF-1 signaling pathway
|
|
Sphingolipid signaling pathway
|
|
PI3K-Akt signaling pathway
|
|
VEGF signaling pathway
|
|
Platelet activation
|
|
Estrogen signaling pathway
|
|
Oxytocin signaling pathway
|
|
Nitrogen metabolism
|
|
Proximal tubule bicarbonate reclamation
|
|
Collecting duct acid secretion
|
|
Gastric acid secretion
|
|
Pancreatic secretion
|
|
Bile secretion
|
|
Prolactin signaling pathway
|
|
Ubiquinone and other terpenoid-quinone biosynthesis
|
|
Tyrosine metabolism
|
|
Phenylalanine metabolism
|
|
Metabolic pathways
|
|
Arachidonic acid metabolism
|
|
Ras signaling pathway
|
|
Rap1 signaling pathway
|
|
cAMP signaling pathway
|
|
Phosphatidylinositol signaling system
|
|
Oocyte meiosis
|
|
Adrenergic signaling in cardiomyocytes
|
|
Vascular smooth muscle contraction
|
|
Long-term potentiation
|
|
Neurotrophin signaling pathway
|
|
Dopaminergic synapse
|
|
Olfactory transduction
|
|
Phototransduction
|
|
Inflammatory mediator regulation of TRP channels
|
|
GnRH signaling pathway
|
|
Melanogenesis
|
|
Glucagon signaling pathway
|
|
Amphetamine addiction
|
|
Alcoholism
|
|
Pertussis
|
|
Tuberculosis
|
|
Glioma
|
|
Pyrimidine metabolism
|
|
Metabolic pathways
|
|
Steroid hormone biosynthesis
|
|
Ovarian steroidogenesis
|
|
Glycerophospholipid metabolism
|
|
Ether lipid metabolism
|
|
Linoleic acid metabolism
|
|
alpha-Linolenic acid metabolism
|
|
Fat digestion and absorption
|
|
NetPath Pathway
|
IL1 Signaling Pathway
|
|
IL5 Signaling Pathway
|
|
TCR Signaling Pathway
|
|
FSH Signaling Pathway
|
|
EGFR1 Signaling Pathway
|
|
Wnt Signaling Pathway
|
|
IL4 Signaling Pathway
|
|
IL2 Signaling Pathway
|
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RANKL Signaling Pathway
|
|
TSH Signaling Pathway
|
|
TGF_beta_Receptor Signaling Pathway
|
|
Panther Pathway
|
Aminobutyrate degradation
|
|
Pyrimidine Metabolism
|
|
Gamma-aminobutyric acid synthesis
|
|
De novo pyrimidine deoxyribonucleotide biosynthesis
|
|
Cadherin signaling pathway
|
|
CCKR signaling map ST
|
|
Angiogenesis
|
|
Endothelin signaling pathway
|
|
Interleukin signaling pathway
|
|
PI3 kinase pathway
|
|
VEGF signaling pathway
|
|
Hypoxia response via HIF activation
|
|
Oxidative stress response
|
|
Pathwhiz Pathway
|
Degradation of Superoxides
|
|
Aspartate Metabolism
|
|
Glutamate Metabolism
|
|
Beta-Alanine Metabolism
|
|
Valine, Leucine and Isoleucine Degradation
|
|
Propanoate Metabolism
|
|
Angiotensin Metabolism
|
|
Arginine and Proline Metabolism
|
|
Pyrimidine Metabolism
|
|
Purine Metabolism
|
|
Arachidonic Acid Metabolism
|
|
Muscle/Heart Contraction
|
|
Pathway Interaction Database
|
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
|
|
Validated nuclear estrogen receptor alpha network
|
|
FOXA1 transcription factor network
|
|
Insulin Pathway
|
|
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
|
|
Signaling events mediated by PTP1B
|
|
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
|
|
Signaling events mediated by TCPTP
|
|
IGF1 pathway
|
|
EGF receptor (ErbB1) signaling pathway
|
|
Posttranslational regulation of adherens junction stability and dissassembly
|
|
PDGFR-beta signaling pathway
|
|
N-cadherin signaling events
|
|
Plasma membrane estrogen receptor signaling
|
|
Validated transcriptional targets of AP1 family members Fra1 and Fra2
|
|
Angiopoietin receptor Tie2-mediated signaling
|
|
Thromboxane A2 receptor signaling
|
|
SHP2 signaling
|
|
VEGFR1 specific signals
|
|
Signaling events mediated by VEGFR1 and VEGFR2
|
|
PAR1-mediated thrombin signaling events
|
|
Validated nuclear estrogen receptor beta network
|
|
p38 MAPK signaling pathway
|
|
TNF receptor signaling pathway
|
|
BCR signaling pathway
|
|
Role of Calcineurin-dependent NFAT signaling in lymphocytes
|
|
IL2 signaling events mediated by PI3K
|
|
IFN-gamma pathway
|
|
Lissencephaly gene (LIS1) in neuronal migration and development
|
|
ErbB1 downstream signaling
|
|
Regulation of cytoplasmic and nuclear SMAD2/3 signaling
|
|
Calcium signaling in the CD4+ TCR pathway
|
|
Insulin-mediated glucose transport
|
|
Cellular roles of Anthrax toxin
|
|
Regulation of Ras family activation
|
|
Downstream signaling in naï
|
|
|
|
Fc-epsilon receptor I signaling in mast cells
|
|
Reactome
|
Collagen degradation
|
|
Degradation of the extracellular matrix
|
|
Platelet degranulation
|
|
Detoxification of Reactive Oxygen Species
|
|
Metabolism of Angiotensinogen to Angiotensins
|
|
Integrin alphaIIb beta3 signaling
|
|
Regulation of IFNG signaling
|
|
Regulation of IFNA signaling
|
|
Growth hormone receptor signaling
|
|
ROS production in response to bacteria
|
|
Nitric oxide stimulates guanylate cyclase
|
|
Pyrimidine biosynthesis
|
|
Purine salvage
|
|
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
|
|
eNOS activation
|
|
VEGFR2 mediated vascular permeability
|
|
Erythrocytes take up carbon dioxide and release oxygen
|
|
Erythrocytes take up oxygen and release carbon dioxide
|
|
Reversible hydration of carbon dioxide
|
|
Nuclear Receptor transcription pathway
|
|
Oxidative Stress Induced Senescence
|
|
TP53 Regulates Metabolic Genes
|
|
The NLRP3 inflammasome
|
|
Calmodulin induced events
|
|
Translocation of GLUT4 to the plasma membrane
|
|
DARPP-32 events
|
|
Inactivation, recovery and regulation of the phototransduction cascade
|
|
FCERI mediated Ca+2 mobilization
|
|
Ca2+ pathway
|
|
CREB phosphorylation through the activation of CaMKII
|
|
Ras activation uopn Ca2+ infux through NMDA receptor
|
|
Smooth Muscle Contraction
|
|
VEGFR2 mediated cell proliferation
|
|
RHO GTPases activate IQGAPs
|
|
RAF/MAP kinase cascade
|
|
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
|
|
Retinoid metabolism and transport
|
|
Acyl chain remodelling of PC
|
|
Acyl chain remodelling of PE
|
|
Acyl chain remodelling of PI
|
|
WikiPathways
|
TGF beta Signaling Pathway
|
|
Degradation of collagen
|
|
Matrix Metalloproteinases
|
|
Oxidative Stress
|
|
Copper homeostasis
|
|
Detoxification of Reactive Oxygen Species
|
|
Nifedipine Activity
|
|
Amyotrophic lateral sclerosis (ALS)
|
|
Dopamine metabolism
|
|
AGE/RAGE pathway
|
|
Folate Metabolism
|
|
Vitamin B12 Metabolism
|
|
Selenium Micronutrient Network
|
|
GABA synthesis, release, reuptake and degradation
|
|
Alanine and aspartate metabolism
|
|
ACE Inhibitor Pathway
|
|
Metabolism of Angiotensinogen to Angiotensins
|
|
Insulin Signaling
|
|
Growth hormone receptor signaling
|
|
Leptin signaling pathway
|
|
Interferon gamma signaling
|
|
Interferon alpha/beta signaling
|
|
Integrin alphaIIb beta3 signaling
|
|
Monoamine Transport
|
|
Myometrial Relaxation and Contraction Pathways
|
|
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
|
|
Spinal Cord Injury
|
|
Alzheimers Disease
|
|
Effects of Nitric Oxide
|
|
Serotonin Transporter Activity
|
|
Metabolism of nucleotides
|
|
Nucleotide Metabolism
|
|
Mesodermal Commitment Pathway
|
|
Endoderm Differentiation
|
|
EGF/EGFR Signaling Pathway
|
|
JAK/STAT
|
|
Corticotropin-releasing hormone
|
|
Endothelin Pathways
|
|
Metabolism of nitric oxide
|
|
Angiogenesis
|
|
Reversible Hydration of Carbon Dioxide
|
|
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
|
|
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
|
|
SIDS Susceptibility Pathways
|
|
Ovarian Infertility Genes
|
|
Integrated Pancreatic Cancer Pathway
|
|
Nuclear Receptors
|
|
NRF2 pathway
|
|
Nuclear Receptors Meta-Pathway
|
|
Human Complement System
|
|
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
|
|
TNF alpha Signaling Pathway
|
|
Arachidonic acid metabolism
|
|
Eicosanoid Synthesis
|
|
Translocation of GLUT4 to the Plasma Membrane
|
|
Visual phototransduction
|
|
Fc epsilon receptor (FCERI) signaling
|
|
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
|
|
Signaling by the B Cell Receptor (BCR)
|
|
Inositol phosphate metabolism
|
|
DAG and IP3 signaling
|
|
Opioid Signalling
|
|
Muscle contraction
|
|
Metabolism of carbohydrates
|
|
Metapathway biotransformation
|
|
Benzo(a)pyrene metabolism
|
|
Glycerophospholipid biosynthesis
|
