Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| MEP --- Cathepsin B | (S)-3-Methyl-2-(3-naphthalen-1-yl-ureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | {(S)-1-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butyl}-carbamic acid tert-butyl ester | Drug Info |
| MEP --- Cathepsin B | (4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid 1-[(3-dimethylcarbamoylallylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester | Drug Info |
| MEP --- Cathepsin B | 2-(3-phenyl-1-(3-(trifluoromethyl)phenyl)allylidene)hydrazinecarbothioamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethyl]-2-(naphthalene-1-sulfonylamino)-3-phenyl-propionamide | Drug Info |
| MEP --- Cathepsin B | 2-((3,5-dichlorophenyl)(thiophen-2-yl)methylene)hydrazinecarbothioamide | Drug Info |
| MEP --- Cathepsin B | 4'-Isoxazol-5-yl-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | (E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromethyl)phenylcarbamoyloxy)methyl)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)acetamido)but-2-enoate | Drug Info |
| MEP --- Cathepsin B | 3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-dihydro-isobenzofuran-5-ylamino)-3-m-tolyl-propionylamino]-ethoxymethyl}-benzoic acid | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(naphthalene-1-sulfonylamino)-pentanoic acid ((S)-1-formyl-2-methyl-propyl)-amide | Drug Info |
| MEP --- Cathepsin B | N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-(piperidin-1-yl)piperidin-1-yl)thiazol-4-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | [1-(3-tert-Butylsulfanyl-2-oxo-1-phenethyl-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid pyridin-3-ylmethyl ester | Drug Info |
| MEP --- Cathepsin B | 4'-(1-Methyl-piperidin-3-yloxy)-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | 4-Methyl-2-(4''-piperazin-1-yl-biphenyl-3-ylamino)-pentanoic acid cyanomethyl-amide | Drug Info |
| MEP --- Cathepsin B | 4'-(1-Methyl-piperidin-4-yloxy)-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(1,4-dimethylpiperidin-4-yl)thiazol-4-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | [(3,4,5-Trimethoxyphenyl)-(4-methoxy,5-hydroxyphenyl)-ketone]thiosemicarbazone | Drug Info |
| MEP --- Cathepsin B | 1-(1-(3,5-bis(trifluoromethyl)phenyl)-3-phenylpropylidene)thiosemicarbazide | Drug Info |
| MEP --- Cathepsin B | {3-Methyl-1-[2-oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-butyl}-carbamic acid pyridin-3-ylmethyl ester | Drug Info |
| MEP --- Cathepsin B | 2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic acid cyanomethyl-amide | Drug Info |
| MEP --- Cathepsin B | 1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamino)-4-fluoro-4-methyl-1-oxopentan-2-ylamino)-2,2,2-trifluoroethyl)biphenyl-4-yl)cyclopropanecarboxamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-((S)-1-cyano-2-(pyridin-4-yl)ethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide | Drug Info |
| MEP --- Cathepsin B | Allicin | Drug Info |
| MEP --- Cathepsin B | (S)-N-(1-(cyanomethylamino)-3-(3-(1-methyl-1H-pyrazol-4-yl)phenyl)-1-oxopropan-2-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | [1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarbamoyl)-3-methyl-butyl]-carbamic acid pyridin-4-ylmethyl ester | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(3-naphthalen-1-yl-thioureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(3-phenyl-thioureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | benzyl (S)-1-((S)-4-fluoro-3-oxo-1-phenylbutan-2-ylamino)-1-oxo-3-phenylpropan-2-ylcarbamate | Drug Info |
| MEP --- Cathepsin B | (S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-2-ylamino)-pentanoic acid cyanomethyl-amide | Drug Info |
| MEP --- Cathepsin B | N-((S)-3-(naphthalen-2-yl)-1-oxo-1-((S)-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)propan-2-yl)-1-naphthamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenylamino-3-m-tolyl-propionamide | Drug Info |
| MEP --- Cathepsin B | 1-((3,5-dichlorophenyl)(p-tolyl)methylene)thiosemicarbazide | Drug Info |
| MEP --- Cathepsin B | Z-Phe-Ala-H | Drug Info |
| MEP --- Cathepsin B | (R)-N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(3-aminopyrrolidin-1-yl)thiazol-4-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-(3-(3-(1H-pyrazol-4-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | 4'-[Methyl-(1-methyl-pyrrolidin-3-yl)-amino]-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide | Drug Info |
| MEP --- Cathepsin B | 1-((3-fluorophenyl)(p-tolyl)methylene)thiosemicarbazide | Drug Info |
| MEP --- Cathepsin B | SID90419368 | Drug Info |
| MEP --- Cathepsin B | (S)-N-((S)-1-cyano-2-phenylethyl)-3-cyclopropyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)propanamide | Drug Info |
| MEP --- Cathepsin B | (S)-3-Methyl-2-(naphthalene-2-sulfonylamino)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide | Drug Info |
| MEP --- Cathepsin B | 3R-(2-oxo-1-(2-oxo-2-(4-oxopent-2-enylamino)ethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)methyl 4-chloro-2-(trifluoromethyl)phenylcarbamate | Drug Info |
| MEP --- Cathepsin B | 3-[(R)-2-Cyano-2-((S)-3-phenyl-2-phenylamino-propionylamino)-ethoxymethyl]-benzoic acid | Drug Info |
| MEP --- Cathepsin B | N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-5-bromothiophene-2-carboxamide | Drug Info |
| MEP --- Cathepsin B | (4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid (3R)-2-oxo-1-{[4-oxo-(1S)-1-phenethylpent-2-enylcarbamoyl]-methyl}-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethylester | Drug Info |
| MEP --- Cathepsin B | 2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid | Drug Info |
| MEP --- Cathepsin B | N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-(2-methoxyethyl)piperazin-1-yl)thiazol-4-yl)benzamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethyl]-3-(naphthalene-1-sulfonylamino)-succinamic acid methyl ester | Drug Info |
| MEP --- Cathepsin B | 4-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid | Drug Info |
| MEP --- Cathepsin B | (S)-2-((S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2,2,2-trifluoroethylamino)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methylpentanamide | Drug Info |
| MEP --- Cathepsin B | (S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)-methyl]-2-(3-oxo-1,3-dihydro-isobenzofuran-5-ylamino)-3-m-tolyl-propionamide | Drug Info |
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