Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5RBN
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| Drug Name |
(S)-3-Methyl-2-(3-phenyl-thioureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide
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| Synonyms |
CHEMBL1791000
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H28N4O2S
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| Canonical SMILES |
CC[C@@H](C)[C@H](\\N=C(/S)\\Nc1ccccc1)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C=O
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| InChI |
InChI=1S/C24H28N4O2S/c1-3-16(2)22(28-24(31)27-18-9-5-4-6-10-18)23(30)26-19(15-29)13-17-14-25-21-12-8-7-11-20(17)21/h4-12,14-16,19,22,25H,3,13H2,1-2H3,(H,26,30)(H2,27,28,31)/t16-,19-,22+/m1/s1
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| InChIKey |
ZBTGGZNSFPJDHD-PERKRYKHSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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