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Target General Information |
Top |
Target ID |
T84486 |
Target Info
|
Target Name |
Oxytocin receptor (OTR) |
Synonyms |
OT-R |
Target Type |
Successful Target |
Gene Name |
OXTR |
Biochemical Class |
GPCR rhodopsin |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
Top |
miRNA Mature ID |
hsa-miR-21-5p |
miRNA Info
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miRNA Mature AC |
|
Sequence |
uagcuuaucagacugauguuga
|
miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-21-5p targets the OXTR. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[1] |
Representative Target(s) Regulated by This miRNA |
Apoptosis antigen ligand (CD178)
|
Target Info
|
|
Apoptosis regulator Bcl-2 (BCL-2)
|
Target Info
|
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miRNA Mature ID |
hsa-miR-451a |
miRNA Info
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miRNA Mature AC |
|
Sequence |
aaaccguuaccauuacugaguu
|
miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-451a target OXTR. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[1] |
Representative Target(s) Regulated by This miRNA |
Apoptosis regulator Bcl-2 (BCL-2)
|
Target Info
|
|
Extracellular signal-regulated kinase 2 (ERK2)
|
Target Info
|
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References |
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REF 1 |
Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex. Mol Autism. 2015 Aug 14;6:46.
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