Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T14731 | Target Info | |||
| Target Name | NAD-dependent deacetylase sirtuin-1 (SIRT1) | ||||
| Synonyms |
hSIRT1; hSIR2; SIR2L1; SIR2-like protein 1; Regulatory protein SIR2 homolog 1; NAD-dependent protein deacetylase sirtuin-1
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| Target Type | Clinical trial Target | ||||
| Gene Name | SIRT1 | ||||
| Biochemical Class | Carbon-nitrogen hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 231 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
SNDX-275
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Phase 3 | Compound Info | ||
| Synonyms |
Entinostat; Histone Deacetylase Inhibitor I; IN1470; MS 275; SNDX 275; MS 27-275; Ms-275; Entinostat (USAN/INN); MS-27-275; Pyridin-3-ylmethyl 4-(2-aminophenylcarbamoyl)benzylcarbamate; Pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate; Pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Pyridin-3-ylmethyl{4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl] methyl]-, 3-pyridinylmethyl ester; Carbamic acid, [[4-[[(2-aminophenyl)carbaonyl]phenyl]methyl]-, 3-pyridinylmethyl ester; Entinostat, SNDX-275, MS-27-275, MS-275; N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide; N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide; Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3-pyridinylmethyl ester; 3-Pyridinylmethyl ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)carbamate
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
BDBM50363780
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Patented | Compound Info | ||
| Synonyms |
CHEMBL1945260; CHEMBL1962973; BDBM50363780
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| Activity |
IC50 = 62100 nM
|
[2] | |||
| Compound Name |
BDBM50363773
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Patented | Compound Info | ||
| Synonyms |
CHEMBL1945137; CHEMBL1962885; BDBM50363773
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| Activity |
IC50 = 64800 nM
|
[2] | |||
| Compound Name |
PAULLONE
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Investigative | Compound Info | ||
| Synonyms |
Paullone; 142273-18-5; 7,12-Dihydroindolo[3,2-d][1]benzazepin-6(5H)-one; CHEMBL430574; NSC641166; NSC 641166; 7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one; 8,18-diazatetracyclo[9.7.0.0; {12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one; AC1Q6O0K; AC1L7YZ4; BDBM7287; SCHEMBL3178594; CTK4C3026; DTXSID30327277; CHEBI:138487; ZINC1626613; AKOS024113922; NSC-641166; NCI60_013826; RT-014947; FT-0673529
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
AGK2
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Investigative | Compound Info | ||
| Synonyms |
AGK-2; AGK 2
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Bisindolylmaleimide-I
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Investigative | Compound Info | ||
| Synonyms |
Bisindolylmaleimide i; bisindolylmaleimide i; 133052-90-1; GF 109203X; GF109203X; Go 6850; GF-109203X; RBT205 INHIBITOR; Go-6850; UNII-L79H6N0V6C; 6850; Bisindolylmaleimide I (GF 109203X); CHEMBL7463; 3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE; 3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione; L79H6N0V6C; QMGUOJYZJKLOLH-UHFFFAOYSA-N; 2-[1-(3-dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl)maleimide; GF-109203; Go6850
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
diphenylamine-2-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
N-phenylanthranilic acid; fenamic acid
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| Activity |
IC50 = 68000 nM
|
[5] | |||
| Compound Name |
5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline
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Investigative | Compound Info | ||
| Synonyms |
(4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone; CHEMBL226115; (4-chlorophenyl)(4-(8-nitroquinolin-5-yl)piperazin-1-yl)methanone; (4-chlorophenyl)-[4-(8-nitro-5-quinolinyl)-1-piperazinyl]methanone; Methanone,(4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-; (4-chlorophenyl)[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone; ACMC-20ejph; CBMicro_046888; Oprea1_532455; SCHEMBL6267516; CTK4A9445; DTXSID30398200; HMS3261L20; ZINC4543674; Tox21_500619; BDBM50216685; CPNQ, >=98% (HPLC), solid; MFCD02039810; STK148613; AKOS000424462; CCG-221923; LP00619; MCULE-5005665656; SDCCGSBI-0046858.P002; NCGC00186018-01; NCGC00261304-01; ST073924; BIM-0046858.P001; B7209; EU-0040310; SR-01000452429; J-003317; SR-01000452429-1; BRD-K04722205-001-01-1; Q27216092; 4-chlorophenyl 4-(8-nitro(5-quinolyl))piperazinyl ketone; Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-[(4,6-Dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
SirReal2; SirReal 2; CHEMBL3770903; C22H20N4OS2; SCHEMBL20609259; SirReal2, >=98% (HPLC); ZINC818861; BDBM50148781; s7845; STL019057; AKOS000651216; CCG-268892; MCULE-6908094772; NCGC00387496-01; NCGC00387496-03; HY-100591; CS-0019744; ST50111553; AB00358713-02; Q27454123; F1762-0644
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
N-(2-(1-(Thieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)pivalamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2338821; SCHEMBL16023502; BDBM50431098; ZINC95591886; DA-27476; 2,2-dimethyl-N-[2-(1-thieno[3,2-d]pyrimidin-4-ylpiperidin-4-yl)ethyl]propanamide
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
2-Cyano-N-(quinolin-8-yl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225914; SCHEMBL10065537; DTXSID70360825; ZINC943066; SMSF0008510; BDBM50216687; AKOS001021423; CB00298; ST50077821; F0344-1620
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
Nicotinamide
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Investigative | Compound Info | ||
| Synonyms |
niacinamide; 3-Pyridinecarboxamide; pyridine-3-carboxamide; Nicotinic acid amide; vitamin PP; Papulex; Aminicotin; Amixicotyn; Nicobion; Nicotylamide; Nikotinamid; Savacotyl; Benicot; Dipegyl; Endobion; Hansamid; Pelmine; Nicotinic amide; Delonin amide; Pelonin amide; Vi-Nicotyl; Austrovit PP; Inovitan PP; Vitamin B; Nicosylamide; Nicotilamide; Nicotililamido; Amnicotin; Niacevit; Nicamina; Nicamindon; Nicofort; Nicomidol; Nicotamide; Nicovitina; Nicovitol; Nicozymin; Niocinamide; Niozymin; Niamide; Nicasir; Nicogen; Nicota; Nicotol; Nicovit; Niko-tamin; 3-Carbamoylpyridine; Nicotine acid amide; Nandervit-N; Pyridine-3-carboxylic acid amide; Niavit PP; Nicosan 2; Nicotine amide; beta-Pyridinecarboxamide; Nikotinsaeureamid; Nicotylamidum; Mediatric; Nicotinsaureamid; Pyridine, 3-carbamoyl-; 3-Pyridinecarboxylic acid amide; Nicotinamidum; m-(Aminocarbonyl)pyridine; Acid amide; Factor pp; Nicotinamida; Nicovel; Vitamin B (VAN); Pelmin; Amid kyseliny nikotinove; Witamina PP; PP-Faktor; Amide PP; Nicotinsaureamid [German]; Nikotinsaeureamid [German]; Amid kyseliny nikotinove [Czech]; Nicotinamidum [INN-Latin]; Nicotinamida [INN-Spanish]; Nictoamide; CCRIS 1901; Dipigyl; HSDB 1237; Vi-noctyl; AI3-02906; Nicotinamide (Vitamin B3); NSC 13128; b-Pyridinecarboxamide; Niacinamide [USP]; UNII-25X51I8RD4; 3-(aminocarbonyl)pyridine; MFCD00006395; .beta.-Pyridinecarboxamide; CHEMBL1140; MLS000069714; 25X51I8RD4; NSC13128; Niacinamide (USP); NSC-13128; NSC-27452; Nicotinamide, 99%; NCGC00093354-03; NCGC00093354-05; SMR000058212; DSSTox_CID_929; Niacinamide;Nicotinic acid amide;Vitamin B3; WLN: T6NJ CVZ; DSSTox_RID_75873; DSSTox_GSID_20929; Niacinamide [USAN]; Enduramide; B3, Vitamin; Vitamin B 3; B 3, Vitamin; 3 Pyridinecarboxamide; SR-01000721872; Nicotinsaureamid Jenapharm; EINECS 202-713-4; Jenapharm, Nicotinsaureamid; Niacotinamide; Nicotinamid; nicotin-amide; Nicotinsaeureamid; 3-Amidopyridine; DEA No. 1405; Nicotinamide,(S); Vitamin B3 amide; 3-yridinecarboxamide; Nicotinamide [INN]; ACMC-20aizz; Mediatric (Salt/Mix); niacin - Vitamin B3; Opera_ID_775; Niacinamide(Vitamin B3); bmse000281; MolMap_000061; EC 202-713-4; SCHEMBL2926; Nicotinamide (JP17/INN); KSC237G2T; MLS001424246; SCHEMBL6278767; SGCUT00176; ZINC5878; DTXSID2020929; SCHEMBL19978192; BDBM27507; Nicotinamide, niacin, vitamin B3; HMS2052M21; HMS2090B05; HMS2093H03; HMS2236J03; HMS3370F21; HMS3394M21; HMS3655M20; HMS3713B22; HMS3884A16; Pharmakon1600-01505397; BCP07322; HY-B0150; Nicotinamide (Vitamin B3) solution; NSC27452; to_000073; Nicotinamide 1.0 mg/ml in Methanol; Nicotinamide, >=98.5% (HPLC); Nicotinamide, >=99.5% (HPLC); Tox21_111202; Tox21_201716; Tox21_302776; ANW-75549; BBL013003; NSC759115; s1899; SBB004283; STL163867; AKOS005715850; Tox21_111202_1; CCG-101149; CS-1968; DB02701; MCULE-3532732201; NC00399; NSC-759115; Nicotinamide, >=98% (HPLC), powder; NCGC00093354-04; NCGC00093354-06; NCGC00093354-09; NCGC00256432-01; NCGC00259265-01; AS-13845; Nicotinamide, puriss., 99.0-101.0%; SC-18039; Nicotinamide 10 microg/mL in Acetonitrile; Nicotinamide, tested according to Ph.Eur.; SBI-0206826.P001; DB-057754; FT-0631517; FT-0672696; FT-0773644; N0078; N1651; ST51037366; SW197779-3; EN300-15612; Niacinamide, meets USP testing specifications; 3418-EP2281816A1; 3418-EP2281818A1; 3418-EP2285778A1; 3418-EP2287165A2; 3418-EP2295424A1; 3418-EP2307377A1; 3418-EP2307378A1; 3418-EP2308858A1; 3418-EP2308874A1; 3418-EP2311808A1; 3418-EP2311829A1; C00153; D00036; J10422; Nicotinamide (Niacinamide), analytical standard; W-3583; 11783-EP2269610A2; 11783-EP2289510A1; 11783-EP2316457A1; 11783-EP2316458A1; 11783-EP2316825A1; 11783-EP2316826A1; 11783-EP2316827A1; 11783-EP2316828A1; AB00373895-13; AB00373895_15; AB00373895_16; Nicotinamide, Vetec(TM) reagent grade, >=98%; A845925; AC-907/25014114; Q192423; Q-201470; SR-01000721872-3; SR-01000721872-4; SR-01000721872-5; Z33546463; F2173-0513; A186B02E-6C70-4E54-9739-79398D439AAA
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| Activity |
IC50 = 50000 nM
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[7] | |||
| Compound Name |
Cambinol analog, 6x
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL491573; BDBM29054
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| Activity |
IC50 = 50000 nM
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[9] | |||
| Compound Name |
4-(Ethylamino)thieno[3,2-d]pyrimidine-6-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2332048; SCHEMBL16023443; BDBM50431111; ZINC95588965; DA-22207; FT-0758725; Thieno[3,2-d]pyrimidine-6-carboxamide, 4-(ethylamino)-
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
3-(5-(2-Chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-5-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL228175; ZINC943069; SMSF0008610; BDBM50216691; AKOS001027775; CB00087; ST50077786; 3-(5-(2-CHLOROPHENYL)-2-FURYL)-2-CYANO-N-(5-QUINOLINYL)ACRYLAMIDE; (2E)-3-[5-(2-chlorophenyl)(2-furyl)]-2-cyano-N-(5-quinolyl)prop-2-enamide
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
3-(Azepan-1-ylsulfonyl)-N-(3-bromophenyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
UNII-308B6B695N; C19H21BrN2O3S; CHEMBL3222141; 308B6B695N; 3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide; 3-(azepane-1-sulfonyl)-N-(3-bromophenyl)benzamide; Oprea1_876929; MLS006011706; SIRT2 Inhibitor II, AK-7; SCHEMBL1095726; DTXSID30194926; HMS3740I05; HMS3886F07; BCP09325; EX-A4162; ZINC1159030; BDBM50008859; MFCD03140195; s5914; AKOS001632674; Benzamide, N-(3-bromophenyl)-3-((hexahydro-1H-azepin-1-yl)sulfonyl)-; CS-3223; MCULE-6804773508; NE52645; AK-7, >=98% (HPLC); NCGC00347936-01; NCGC00347936-06; BS-16806; DA-35352; HY-16691; SMR004703433; EU-0004902; FT-0702786; Y1898; A12904; AB00115363-01; SR-01000432494; 3-(1-azepanylsulfonyl-)-N-(3-bromophenyl)benzamide; SR-01000432494-1; Q27255930; N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]benzamide
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| Activity |
IC50 ~ 50000 nM
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[10] | |||
| Compound Name |
N-Methyl-4-(4-(2-pivalamidoethyl)piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2338820; SCHEMBL16023444; BDBM50431099; ZINC95592542; DA-21543
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
3-(5-(2-Chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-8-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225971; (E)-3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-8-yl)acrylamide; ZINC943061; BDBM50216686; AKOS002185214; ST50077790; F0344-1610; (2E)-3-[5-(2-chlorophenyl)(2-furyl)]-2-cyano-N-(8-quinolyl)prop-2-enamide
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
Chembl4217034
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Investigative | Compound Info | ||
| Activity |
IC50 ~ 50000 nM
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[11] | |||
| Compound Name |
2-Cyano-N-(quinolin-5-yl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225797; SCHEMBL10065540; ZINC943067; BDBM50216688; AKOS001027800; 2-CYANO-N-(5-QUINOLINYL)-3-(5-(3-(TRIFLUOROMETHYL)PHENYL)-2-FURYL)ACRYLAMIDE
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
Chembl4218670
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Investigative | Compound Info | ||
| Activity |
IC50 ~ 50000 nM
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[11] | |||
| Compound Name |
4-Chlorothieno[3,2-d]pyrimidine-6-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2332049; MFCD28098923; SCHEMBL16011549; BDBM50431110; ZINC95587098; BS-15119; DA-39503; SY265452; FT-0767097; Thieno[3,2-d]pyrimidine-6-carboxamide, 4-chloro-
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
Chembl4211748
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Investigative | Compound Info | ||
| Activity |
IC50 ~ 50000 nM
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[11] | |||
| Compound Name |
2-Cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL390332; ZINC943073; SMSF0008652; BDBM50216693; STK841558; AKOS001027776; CB00144; (2E)-2-cyano-3-[5-(2,3-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
N-(5-Benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
SirReal-1; CHEMBL3769988; N-(5-Benzylthiazol-2-yl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide; BAS 09687674; SirReal1; ZINC818843; BDBM50148776; STL019032; AKOS000651417; MCULE-7999871379; J3.601.436I; Q27454126; N-[(4,6-Dimethyl-2-pyrimidinylthio)acetyl]-5-benzylthiazole-2-amine
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
2-Cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(quinolin-8-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226027; SMSF0008553; ZINC1751305; BDBM50216690; AKOS002185154; CB00152; ST50077753; (2E)-3-[5-(2,3-dichlorophenyl)(2-furyl)]-2-cyano-N-(8-quinolyl)prop-2-enamide
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
4-[4-[2-(2,2-Dimethylpropanoylamino)ethyl]piperidin-1-yl]thieno[3,2-d]pyrimidine-6-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2338819; SCHEMBL16023441; BDBM50431100; ZINC95591497; DA-21541
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
Bisindolylmaleimide v
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Investigative | Compound Info | ||
| Synonyms |
1-Methyl-3,4-bis(3-indolyl)maleimide; 3,4-di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione; Ro 31-6045; 3,4-bis(1H-indol-3-yl)-1-methylpyrrole-2,5-dione; 2,3-bis(1H-Indol-3-yl)-N-methylmaleimide; CHEMBL291725; 3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione; 3,4-bis(1H-indol-3-yl)-1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione; 3,4-Di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-1-methyl-; 1H-Pyrrole-2,5-dione,3,4-di-1H-indol-3-yl-1-methyl-; N-Methylbis(indol-3-yl)maleimide; Methylarcyriarubin; N-Methyl-3,4-bis(indol-3-yl)maleimide; PubChem12896; 1-Methyl-3,4-bis(indol-3-yl)maleimide; ACMC-20d3xw; BIM V; Bisindolylmaleimide deriv. 4; BDBM2582; SCHEMBL3945882; CTK4A8537; AOB5920; DTXSID50150620; HMS3229B11; HMS3401G13; HMS3648M04; KS-000025YD; ZINC2560263; HSCI1_000201; MFCD00236433; AKOS015920082; GS-3766; Ro31-6045; BR-15402; FT-0726870; Bisindolylmaleimide V - CAS 113963-68-1; S-7012; 963B681; A803111; SR-01000946387; J-003042; SR-01000946387-1; BRD-K07780396-001-01-5
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
SIRT2 Inhibitor, Inactive Control, AGK7
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226026; SMSF0008496; ZINC1220115; BDBM50216692; AKOS002185363; CB00296; ST50077772; J-017985; 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-8-yl)acrylamide; (2E)-3-[5-(2,5-dichlorophenyl)(2-furyl)]-2-cyano-N-(8-quinolyl)prop-2-enamide; 2-Propenamide, 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-8-quinolinyl-
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
Chembl4218205
Click to Show/Hide
|
Investigative | Compound Info | ||
| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
2-Thioxo-1,2-dihydro-5-[(biphenyl-4-yl)methylene]pyrimidine-4,6(3H,5H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795371; NSC684571; ZINC6575888; BDBM50346551; AKOS005131211; NSC-684571; NCI60_030385
Click to Show/Hide
|
||||
| Activity |
IC50 = 50500 nM
|
[12] | |||
| Compound Name |
5-[[3-[(2-Phenylacetyl)amino]phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3806002; SCHEMBL18339542; BDBM50168835
Click to Show/Hide
|
||||
| Activity |
IC50 = 50800 nM
|
[13] | |||
| Compound Name |
Methyl (2S)-2-[[(2S)-2-acetamido-6-(ethanethioylamino)hexanoyl]amino]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835300; BDBM50355042
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[14] | |||
| Compound Name |
3-(2-Furyl)-6-[(2-methoxyphenoxy)methyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311084; ZINC4511810; BDBM50044822; STK824443; AKOS000652050; CCG-275436; MCULE-3999666870; AO-365/43300816; 3-(furan-2-yl)-6-[(2-methoxyphenoxy)methyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 51200 nM
|
[15] | |||
| Compound Name |
US9365508, C6 (3-CF3,
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3986268; BDBM235913
Click to Show/Hide
|
||||
| Activity |
IC50 = 51700 nM
|
[2] | |||
| Compound Name |
2-(3-Biphenylylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540468; 2-(Biphenyl-3-ylamino)benzamide; BDBM50297161
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[16] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phenyl)acrylamido)piperidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244160; BDBM50241183; (E)-N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phenyl)acrylamido)piperidine-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[17] | |||
| Compound Name |
5-[[3-(Naphthalene-2-carbonylamino)phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805112; SCHEMBL18340112; BDBM50168831
Click to Show/Hide
|
||||
| Activity |
IC50 = 52100 nM
|
[13] | |||
| Compound Name |
N-[1-(5-Carbamoyl-3-pyridyloxy)-5-naphthyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3343652; BDBM50030100
Click to Show/Hide
|
||||
| Activity |
IC50 = 52700 nM
|
[18] | |||
| Compound Name |
(5E)-1-Ethyl-5-[(4-phenylmethoxyphenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2203541; BDBM50400728
Click to Show/Hide
|
||||
| Activity |
IC50 = 53200 nM
|
[12] | |||
| Compound Name |
Propan-2-yl N-[4-[(3-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4059756; BDBM50267662
Click to Show/Hide
|
||||
| Activity |
IC50 = 54800 nM
|
[19] | |||
| Compound Name |
N-[(E)-(3,5-Dibromo-2,4-dihydroxyphenyl)methylideneamino]quinoline-6-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333659; BDBM50428994
Click to Show/Hide
|
||||
| Activity |
EC50 = 55200 nM
|
[20] | |||
| Compound Name |
2-(4-Chloroanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152572; 2-[(4-chlorophenyl)amino]benzamide; Oprea1_738529; 2-(4-Chlorophenylamino)Benzamide; ZINC481300; BDBM50392068; MCULE-6884817479; AJ-333/13050075
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[16] | |||
| Compound Name |
5-(5-Octyl-2-propan-2-yl-3,4-dihydro-1H-pyrido[4,3-b]indol-8-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408980; SCHEMBL16978507; BDBM50070594
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[21] | |||
| Compound Name |
2-Anilinobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(phenylamino)benzamide; Benzamide, 2-(phenylamino)-; Benzamide, o-anilino-; CHEMBL561194; BRN 0782669; Anilinobenzamide; NSC75183; 2-Phenylaminobenzamide; 2-phenylamino-benzamide; 3-14-00-00903 (Beilstein Handbook Reference); ARONIS26963; SCHEMBL1318994; DTXSID50153151; KUC112561N; BENZAMIDE,2-(PHENYLAMINO)-; KS-00000S3U; KS-000048GW; ZINC1674116; BDBM50297159; MFCD00476529; NSC-75183; AKOS005279221; DS-8370; MCULE-6691808486; KSC-321-003; AK145944; DS-009752; BRD-K79647146-001-01-2
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[16] | |||
| Compound Name |
(5E)-1-Methyl-5-[(4-phenylmethoxyphenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2203540; BDBM50400725; ZINC95559058
Click to Show/Hide
|
||||
| Activity |
IC50 = 56500 nM
|
[12] | |||
| Compound Name |
Ethyl 2-(4-morpholinophenyl)-1H-benzimidazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752305
Click to Show/Hide
|
||||
| Activity |
IC50 = 57500 nM
|
[22] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-(6-benzylsulfanylhexanoylamino)-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883598; BDBM50209630
Click to Show/Hide
|
||||
| Activity |
IC50 = 57700 nM
|
[23] | |||
| Compound Name |
2-(3-Phenoxyphenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL549853; BDBM50297163
Click to Show/Hide
|
||||
| Activity |
IC50 = 58000 nM
|
[16] | |||
| Compound Name |
3-[3-(2-Carbamoylphenylamino)phenyl]acrylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551010; BDBM50297165
Click to Show/Hide
|
||||
| Activity |
IC50 = 58000 nM
|
[16] | |||
| Compound Name |
Tenovin-6
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Tenovin 6; CHEMBL595354; MFCD11976906; C25H34N4O2S; 4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)phenylcarbamothioyl)benzamide; Tnv 6; SCHEMBL907478; US8501991, Tenovin 6; BDBM99917; CTK8E8404; AOB3690; DTXSID50647242; EX-A350; HMS3648C14; HMS3652F12; BCP08547; 2064AH; ZINC43196009; AKOS026750220; CCG-208692; CS-1976; NCGC00263616-04; AC-32966; AS-16762; DA-48390; HY-15510; QC-10485; AB0098114; Tenovin6 ;Tenovin 6;Tnv-6; Tnv6;Tnv 6; FT-0708864; SW220061-1; A12305; SR-01000946351; J-000331; SR-01000946351-1; Q27147321
Click to Show/Hide
|
||||
| Activity |
IC50 = 58100 nM
|
[24] | |||
| Compound Name |
5-[(2-Hydroxynaphthalen-1-yl)methyl]-1-[(4-methoxyphenyl)methyl]-6-phenyl-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219559
Click to Show/Hide
|
||||
| Activity |
IC50 = 58200 nM
|
[25] | |||
| Compound Name |
1-(2-Hydroxyethyl)-2-[4-(dimethylamino)phenyl]-1H-benzoimidazole-5-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105180; BDBM50445823
Click to Show/Hide
|
||||
| Activity |
IC50 = 58430 nM
|
[26] | |||
| Compound Name |
3-(2-Furyl)-6-(2-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1576457; MLS000041192; HMS2278M04; ZINC4295413; BDBM50044816; STK298205; AKOS000651823; MCULE-8765825666; SDCCGSBI-0138919.P001; SMR000046953; ST50294624; AO-365/43300844; 3-(2-furyl)-6-(2-pyridyl)-1,2,4-triazolo[3,4-b]1,3,4-thiadiazoline; 3-(furan-2-yl)-6-(pyridin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
Ki = 58900 nM
|
[15] | |||
| Compound Name |
4-Tert-butyl-N-[[4-[[2-[2-[2-[2-[2-[2-(dimethylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945134; SCHEMBL907374
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[27] | |||
| Compound Name |
4-Tert-butyl-N-[[4-[[2-[2-[2-[2-[2-[2-(dimethylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]phenyl]carbamothioyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1962883; BDBM99921; US8501991, 8
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[28] | |||
| Compound Name |
2-(3-Hydroxymethylphenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561596; BDBM50297166; 2-(3-(Hydroxymethyl)Phenylamino)Benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[16] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-4-propylbenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945136; SCHEMBL1708338
Click to Show/Hide
|
||||
| Activity |
IC50 = 60200 nM
|
[27] | |||
| Compound Name |
Ethyl 2-[4-(dimethylamino)phenyl]-1-[3-(2-oxopyrrolidin-1-yl)propyl]benzimidazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290210; BDBM50021512
Click to Show/Hide
|
||||
| Activity |
IC50 = 60310 nM
|
[24] | |||
| Compound Name |
3-(2-Furyl)-6-(phenoxymethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1613321; MLS000081191; HMS2399J08; ZINC528057; BDBM50044806; STK298186; AKOS000651936; CCG-274743; MCULE-6391504371; NCGC00019303-01; NCGC00019303-02; SMR000043317; ST50294610; AO-365/41329021; [(3-(2-furyl)-1,2,4-triazolo[3,4-b]1,3,4-thiadiazolin-6-yl)methoxy]benzene; 3-(furan-2-yl)-6-(phenoxymethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 61300 nM
|
[15] | |||
| Compound Name |
5-[(2-Methoxynaphthalen-1-yl)methyl]-6-phenyl-1-[(4-propoxyphenyl)methyl]-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219552
Click to Show/Hide
|
||||
| Activity |
IC50 = 61900 nM
|
[25] | |||
| Compound Name |
US9365508, D3 (3-Cl, 4-OMe,
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3963404; BDBM235915
Click to Show/Hide
|
||||
| Activity |
IC50 = 62500 nM
|
[2] | |||
| Compound Name |
CCOC(=O)c1ccc2[nH]c(nc2c1)-c1ccc(cc1)N(C)C
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752617; SCHEMBL19994487; ethyl 2-(4-dimethylaminophenyl)-1H-benzimidazole-5-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 = 62900 nM
|
[22] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-2-[[(2S)-2,6-diacetamidohexanoyl]amino]-6-(phenylcarbamothioylamino)hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3601366; BDBM50106872
Click to Show/Hide
|
||||
| Activity |
IC50 = 62900 nM
|
[29] | |||
| Compound Name |
8-(2-Aminopyrimidin-5-yl)-5-octyl-3,4-dihydro-1H-pyrido[4,3-b]indole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408814; SCHEMBL16978499; BDBM50070592
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[21] | |||
| Compound Name |
Chembl4288567
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL17737200
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[30] | |||
| Compound Name |
N-[1-(5-Carbamoyl-3-pyridyloxy)-5-naphthyl]-3-nitrobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3343654; BDBM50030103
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[18] | |||
| Compound Name |
3-[3-(2-Carbamoylphenylamino)phenyl]acrylic acidmethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558854; BDBM50297164
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[16] | |||
| Compound Name |
N-[3-[(5-Carbamoylpyridin-3-yl)oxymethyl]phenyl]-1,3-benzothiazole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805790; SCHEMBL18340249; BDBM50168827
Click to Show/Hide
|
||||
| Activity |
IC50 = 65200 nM
|
[13] | |||
| Compound Name |
3-(2-Furyl)-6-(3,4,5-triethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311064; ZINC4938823; BDBM50044789; STK298177; AKOS000746031; MCULE-4019039334; AO-365/43300940; 3-(furan-2-yl)-6-(3,4,5-triethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 65700 nM
|
[15] | |||
| Compound Name |
3-(2-Furyl)-6-(2-pyrazinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310818; ZINC4511828; BDBM50044798; STK298206; AKOS000651853; MCULE-1095084208; AO-365/43300846; 3-(2-furyl)-6-pyrazin-2-yl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole; [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazole, 3-(2-furanyl)-6-(2-pyrazinyl)-; 3-(furan-2-yl)-6-(pyrazin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 66600 nM
|
[15] | |||
| Compound Name |
6-(2,3-Dihydro-1,4-benzodioxin-6-ylmethyl)-3-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311076; ZINC4511824; BDBM50044808; STK298204; AKOS000651822; MCULE-7700095928; AO-365/43300843; 6-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-3-(furan-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[15] | |||
| Compound Name |
3-(Furan-2-yl)-6-(1-phenoxyethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311078; BDBM50044805; STK298198; AKOS003374502; MCULE-5089367131; AO-365/43300822; 1-[3-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]ethyl phenyl ether
Click to Show/Hide
|
||||
| Activity |
IC50 = 67900 nM
|
[15] | |||
| Compound Name |
Sirtinol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL380797; 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide; 2-{[(2-hydroxy-1-naphthyl)methylene]amino}-N-(1-phenylethyl)benzamide; (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide; 2-[[(Z)-(2-oxonaphthalen-1-ylidene)methyl]amino]-N-(1-phenylethyl)benzamide; 2-[(E)-[(2-hydroxynaphthalen-1-yl)methylidene]amino]-N-(1-phenylethyl)benzamide; 2-[(2-oxo-1-naphthalenylidene)methylamino]-N-(1-phenylethyl)benzamide; 2-[(2-hydroxynaphthalen-1-yl)methylideneamino]-N-(1-phenylethyl)benzamide; 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide; Sir Two Inhibitor Naphthol; 2-[(2-oxonaphthalen-1-ylidene)methylamino]-N-[(1R)-1-phenylethyl]benzamide; Probes1_000047; Probes1_000316; Probes2_000084; Probes2_000518; Oprea1_639422; CBDivE_000728; ARONIS007637; SCHEMBL2543371; SCHEMBL8227466; Sirtinol, >=95% (NMR); KS-00003ZNW; HMS3413N18; HMS3651B13; HMS3677N18; BCP22454; EX-A4220; BDBM50156760; MFCD00810186; s2804; STL069068; AKOS000497157; AKOS016842267; AKOS030627556; AB07334; CCG-265000; CS-5291; DS-0089; MCULE-8856934531; Sirtinol - CAS 410536-97-9; VZ23394; SMP2_000018; AC-32747; AK-16605; BR-16605; HY-13515; BCP0726000065; FT-0644594; SW219185-1; W6155; S-5353; BRD-A23747351-001-01-9; Q27140353; Q27215793; 2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide; 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl) benzamide; (E)-2-(((2-HYDROXYNAPHTHALEN-1-YL)METHYLENE)AMINO)-N-(1-PHENYLETHYL)BENZAMIDE; 2-[(2-hydroxy-naphthalen-1-ylmethylene)-amino]-N-(1-phenyl-ethyl)-benzamide; 2-[[(2-HYDROXY-1-NAPHTHALENYL)METHYLENE]AMINO]-N-(1-PHENYLETHYL)BENZAMIDE; 2-{[(E)-(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-(1-phenylethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[31] | |||
| Compound Name |
2-(M-Tolylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(3-Tolyamino)benzamide; CHEMBL560337; BDBM50297160
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[16] | |||
| Compound Name |
5-Benzyl-1-[(4-ethoxyphenyl)methyl]-6-phenyl-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219565
Click to Show/Hide
|
||||
| Activity |
IC50 = 68100 nM
|
[25] | |||
| Compound Name |
5-[5-(Pyridine-3-carbonylamino)naphthalen-1-yl]oxypyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3343656; BDBM50030101
Click to Show/Hide
|
||||
| Activity |
IC50 = 70700 nM
|
[18] | |||
| Compound Name |
3,4-Dichloro-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945266; SCHEMBL1708340
Click to Show/Hide
|
||||
| Activity |
IC50 = 70900 nM
|
[27] | |||
| Compound Name |
3,4-Dichloro-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945266; CHEMBL1962975; BDBM50363784
Click to Show/Hide
|
||||
| Activity |
IC50 = 70900 nM
|
[2] | |||
| Compound Name |
(5-Hydroxy-1-benzofuran-3-yl)-(2-hydroxyphenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314711; BDBM50425975
Click to Show/Hide
|
||||
| Activity |
IC50 = 71400 nM
|
[32] | |||
| Compound Name |
5-[[3-[(4-Cyclohexylbenzoyl)amino]phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805306; SCHEMBL18339345; BDBM50168495
Click to Show/Hide
|
||||
| Activity |
IC50 = 71500 nM
|
[13] | |||
| Compound Name |
2-[3-(2-Hydroxylethyl)phenylamino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL572123; BDBM50297167
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[16] | |||
| Compound Name |
4-(3-(4-(4-Fluorobenzyloxy)phenyl)acrylamido)-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)piperidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215918; BDBM50199445; AB00037964-01
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[17] | |||
| Compound Name |
Ethyl 1-(2-hydroxyethyl)-2-(4-piperidin-1-ylphenyl)benzimidazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105181; BDBM50445822
Click to Show/Hide
|
||||
| Activity |
IC50 = 74520 nM
|
[26] | |||
| Compound Name |
2-(Methyl(Phenyl)Amino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152587; 2-(N-methylanilino)benzamide; SCHEMBL2762268; BDBM50392085; AKOS034377912; MCULE-7499321790
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[5] | |||
| Compound Name |
[3-(2-Furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl 3-methylphenyl ether
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311080; ZINC4938841; BDBM50044802; AKOS000746156; MCULE-5911203977; AO-365/43300807
Click to Show/Hide
|
||||
| Activity |
IC50 = 75300 nM
|
[15] | |||
| Compound Name |
N-[3-[(2-Oxo-1-naphthalenylidene)methylamino]phenyl]-2-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Salermide; CHEMBL597845; N-[3-[[(Z)-(2-oxonaphthalen-1-ylidene)methyl]amino]phenyl]-2-phenylpropanamide; Salemide; SCHEMBL8103931; Salermide, >=98% (HPLC); SCHEMBL16445054; CTK8E9782; AOB5646; DTXSID70693943; HMS3648G04; BCP19469; EX-A1238; 2029AH; BDBM50309827; s8460; AKOS024457988; AKOS032947358; CCG-208708; CS-6203; N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide; AK685527; BS-14362; HY-101073; EC-000.2468; SR-01000946363; J-002449; SR-01000946363-1; BRD-A67788537-001-01-7; Q27166286; SIRT1/2 Inhibitor VIII, Salermide - CAS 1105698-15-4; N-(3-((2-Hydroxynaphthalen-1-yl)methyleneamino)phenyl)-2-phenylpropanamide; (E)-N-(3-((2-hydroxynaphthalen-1-yl)methyleneamino)phenyl)-2-phenylpropanamide; N-(3-{[(2-Oxonaphthalen-1(2H)-ylidene)methyl]amino}phenyl)-2-phenylpropanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 76000 nM
|
[7] | |||
| Compound Name |
2-Bromo-3-(3,5-difluorophenyl)benzofuran-4,6-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4,6-Benzofurandiol,2-bromo-3-(3,5-difluorophenyl)-; SCHEMBL1740998; CHEMBL3698627; BDBM131035; US8835659, 20; 2-bromo-3-(3,5-difluorophenyl)-1-benzofuran-4,6-diol
Click to Show/Hide
|
||||
| Activity |
IC50 = 76300 nM
|
[33] | |||
| Compound Name |
3-(Furan-2-yl)-6-(4-methoxybenzyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311074; ZINC4511801; BDBM50044810; STK298180; AKOS000651850; MCULE-1815595580; AO-365/43300947; 4-{[3-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]methyl}phenyl methyl ether
Click to Show/Hide
|
||||
| Activity |
IC50 = 76900 nM
|
[15] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-[[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]amino]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883514; BDBM50209634
Click to Show/Hide
|
||||
| Activity |
IC50 = 77500 nM
|
[23] | |||
| Compound Name |
6-Chloro-N-hydroxy-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL172124; SCHEMBL16266100; BDBM50178788; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-hydroxyamic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 77600 nM
|
[34] | |||
| Compound Name |
2-Phenylsulfanylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(phenylthio)benzamide; CHEMBL551610; (phenylthio)benzamide; Maybridge3_005605; SCHEMBL1030659; HMS1446O17; BDBM50297168; AKOS033210574; MCULE-3887291595; IDI1_016992
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[16] | |||
| Compound Name |
6-(4-Chlorobenzyl)-3-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311073; ZINC4511800; BDBM50044811; STK298179; AKOS003375110; MCULE-3300718179; AO-365/43300946; 6-(4-chlorobenzyl)-3-(furan-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[15] | |||
| Compound Name |
3-(2-Furyl)-6-(3-pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310817; ZINC4511825; BDBM50044817; STK737880; AKOS000651824; MCULE-7765298301; AO-365/41329024; 3-(2-furyl)-6-(3-pyridyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole; [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazole, 3-(2-furanyl)-6-(3-pyridinyl)-; 3-(furan-2-yl)-6-(pyridin-3-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 78800 nM
|
[15] | |||
| Compound Name |
1-Phenyl-2-(4-methylphenyl)-1H-benzoimidazole-5-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290220; BDBM50021528
Click to Show/Hide
|
||||
| Activity |
IC50 = 79870 nM
|
[24] | |||
| Compound Name |
2-Acetyl-6-chloro-2,3,4,9-tetrahydro-1H-beta-carboline-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199180; BDBM50178782; 2-acetyl-6-chloro-1,3,4,9-tetrahydropyrido[3,4-b]indole-1-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 79900 nM
|
[34] | |||
| Compound Name |
3-(1-Oxoisoindolin-2-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid; 3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid; CHEMBL82949; 3-(3-oxo-1H-isoindol-2-yl)propanoic acid; 3-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)-propanoic acid; TimTec1_008233; MLS000071070; SCHEMBL315339; Methyl2,5-Dimethyl-3-furoate; cid_648461; CTK3E7973; DTXSID10349457; HMS1557G05; HMS2373A20; ZINC487464; KS-00001A8B; 2897AC; BBL012195; BDBM50304354; MFCD03131298; SBB027748; STL163543; AKOS000303484; MCULE-1678440942; 1,4-bipiperidin-3-ol disuccinate (salt); SMR000014614; ST078179; CS-0046992; FT-0677635; Y-0106; 5Z-0825; SR-01000367136; 2H-Isoindole-2-propanoicacid, 1,3-dihydro-1-oxo-; J-510445; SR-01000367136-1; 2H-Isoindole-2-propanoic acid, 1,3-dihydro-1-oxo-; 3-(1-Oxo-1,3-dihydro-2H-isoindole-2-yl)propionic acid; 3-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[35] | |||
| Compound Name |
Ethyl 2-(1,3-benzodioxol-5-yl)-1-(2-hydroxyethyl)benzimidazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105182; BDBM50445821
Click to Show/Hide
|
||||
| Activity |
IC50 = 80110 nM
|
[26] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-2-[[(2S)-2,6-diacetamidohexanoyl]amino]-6-(ethylcarbamothioylamino)hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3601364; BDBM50106874
Click to Show/Hide
|
||||
| Activity |
IC50 = 83400 nM
|
[29] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-2-acetamidopropanoyl]amino]-N-[(2S)-1-(methylamino)-1-oxopropan-2-yl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254217; BDBM50326786; (S)-6-Acetamido-2-((S)-2-acetamidopropanamido)-N-((S)-1-(methylamino)-1-oxopropan-2-yl)hexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[36] | |||
| Compound Name |
(4-Chlorophenyl)-(5-hydroxy-6-methyl-1-benzofuran-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314705; BDBM50425980
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[32] | |||
| Compound Name |
3-(2-Furyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1421246; MLS000081193; HMS2404P17; ZINC528434; BDBM50044797; STK298202; AKOS000652203; MCULE-1985335168; NCGC00019297-01; NCGC00019297-02; SMR000043351; AO-365/41329022; 3-(furan-2-yl)-6-(thiophen-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 88600 nM
|
[15] | |||
| Compound Name |
2-(3-Phenylsulfanylphenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562079; BDBM50297162
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[37] | |||
| Compound Name |
1-Ethyl-6-hydroxy-5-[(Z)-indol-3-ylidenemethyl]-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2203538; BDBM50400737
Click to Show/Hide
|
||||
| Activity |
IC50 = 89300 nM
|
[12] | |||
| Compound Name |
(2S)-N-[(2S)-5-Acetamido-1-amino-1-oxopentan-2-yl]-6-(carbamothioylamino)-2-[[(2S)-2,5-diacetamidopentanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814814; BDBM50350509
Click to Show/Hide
|
||||
| Activity |
IC50 = 89500 nM
|
[29] | |||
| Compound Name |
2-(2-Chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL490905; BDBM50309830; 2-(4''-Iodobenzoyl)-1,2-dihydro-benzo[f]chromen-3-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 89800 nM
|
[38] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-3,4,5-trifluorobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3969622; BDBM235914; US9365508, D1 (3,4,5-F3)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[2] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-3-methylbenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945261
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[27] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-4-methylbenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945257; SCHEMBL1707948
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[27] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-2-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945670; CHEMBL1962976; BDBM50363785
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[2] | |||
| Compound Name |
4-Chloro-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945259; SCHEMBL1707510
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[27] | |||
| Compound Name |
2-Chloro-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945671; SCHEMBL1706965
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[27] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945256; SCHEMBL1707575
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[27] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-4-methoxybenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945258; SCHEMBL1706823
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[27] | |||
| Compound Name |
Cambinol analog, 6e
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL490736; SCHEMBL1711140; BDBM29056; 5-[(2-hydroxynaphthalen-1-yl)methyl]-1-methyl-6-phenyl-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[9] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-2-methylbenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945670; SCHEMBL1707579
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[27] | |||
| Compound Name |
N-[3-[(5-Carbamoylpyridin-3-yl)oxymethyl]phenyl]pyridazine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805503; SCHEMBL18340482; BDBM50168925
Click to Show/Hide
|
||||
| Activity |
IC50 = 90900 nM
|
[13] | |||
| Compound Name |
3-[3-(2-Carbamoylanilino)phenyl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152571; BDBM50392067
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[16] | |||
| Compound Name |
3-(2-Furyl)-6-(1-phenylpropyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311072; BDBM50044812; STK298184; AKOS003373890; MCULE-8221495159; AO-365/43300802; 3-(furan-2-yl)-6-(1-phenylpropyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 96200 nM
|
[15] | |||
| Compound Name |
Chembl4216559
Click to Show/Hide
|
Investigative | Compound Info | ||
| Activity |
IC50 = 97400 nM
|
[39] | |||
| Compound Name |
Thiomyristoyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4129995; benzyl (S)-(1-oxo-1-(phenylamino)-6-tetradecanethioamidohexan-2-yl)carbamate; EX-A4227; BDBM50276140; MFCD30738003; s8245; ZINC616570764; CCG-270137; CS-6258; BS-15398; HY-101278; benzyl N-[(2S)-1-anilino-1-oxo-6-(tetradecanethioylamino)hexan-2-yl]carbamate
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[40] | |||
| Compound Name |
SirReal1-O-propargyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4227975; BDBM50459844; HY-107453; CS-0028512
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
6-Chloro-N,N-diethyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL352865; Oprea1_540979; MLS000114268; SCHEMBL16266016; HMS2251B11; HMS3429E09; BDBM50178785; STK833264; AKOS001638016; CCG-111684; MCULE-8174168267; NCGC00085834-02; SMR000070033; EU-0011153; SR-01000490074; SR-01000490074-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
N-Methyl-2-(phenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-anilino-N-methylbenzamide; CHEMBL2152584; N-Methyl-2-anilinobenzamide; ARONIS26502; ZINC9379154; BDBM50392082; STL256966; AKOS005278800; CCG-286369; MCULE-3736029576; KS-00004844; Z30272269
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(2-Methylphenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152615; BDBM50392113
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
6-(5-(4-Fluorophenyl)furan-2-yl)-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000056278; SMR000068500; MLS001331510; CHEMBL1305963; BDBM34328; cid_1034419; HMS2374G22; ZINC704029; STK731903; AKOS001087753; CCG-120135; MCULE-1724242971; AF-399/42810586; F1711-0179
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
8-(3-Methylphenyl)-5-octyl-3,4-dihydro-1H-pyrido[4,3-b]indole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408826; SCHEMBL16978501; BDBM50070584
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
2-(4-(Benzyloxy)Phenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152577; BDBM50392074
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
5-Chloro-1H,2H,3H-imidazo[4,5-b]pyridine-2-thione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797922; SCHEMBL17513322; BDBM50346548; LT0060; SB21401; 5-chloro-1,3-dihydroimidazo[4,5-b]pyridine-2-thione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
N-(5-{3-[(1-Benzyl-1h-1,2,3-Triazol-4-Yl)methoxy]benzyl}-1,3-Thiazol-2-Yl)-2-[(4,6-Dimethylpyrimidin-2-Yl)sulfanyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Sirt2-IN-1; CHEMBL4228286; BDBM50459842; HY-112427; CS-0046043; Q27455747
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
2-[3-[Methyl-(2-phenylacetyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152609; BDBM50392107
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(3-Chlorophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152624; BDBM50392058
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[5-[(7-Chloronaphthalen-1-yl)methyl]-1,3-thiazol-2-yl]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770049; BDBM50148782
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
N-[4-(2-Carbamoylanilino)phenyl]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152600; BDBM50392098
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Benzamidoanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152594; BDBM50392092
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Cyclohexanecarboxamidophenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152597; BDBM50392095
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-(2-Carbamoylanilino)phenyl]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152601; BDBM50392099
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
6,9-Dimethyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL200924; ChemDiv3_003263; Cambridge id 5169181; Oprea1_404230; CBDivE_008683; MLS000058824; 6,9-dimethyl-1,2,3,4-tetrahydrocarbazole-1-carboxamide; SCHEMBL16266114; HMS1482E07; HMS2401O20; BDBM50178780; MCULE-6872625087; IDI1_021173; SMR000069090; EU-0011163; AB00074825-01; AH-262/31831007; SR-01000490079; SR-01000490079-1; BRD-A22929678-001-01-0
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
2-[3-(Phenylcarbamoyl)anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152602; BDBM50392100
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-(2-Carbamoylphenylamino)Benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152569; BDBM50392065; AKOS005925880
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-[3-(Trifluoromethyl)phenyl]ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152619; BDBM50392052
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Isobutyramidophenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152596; BDBM50392094
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(3-Bromophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152627; BDBM50392061
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[Benzyl(methyl)carbamoyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152605; BDBM50392103
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Phenylanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562473; SCHEMBL8420632; BDBM50392072
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(2-Bromophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152626; BDBM50392060
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(P-Tolylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152573; 2-(4-methylanilino)benzamide; SCHEMBL15688476; BDBM50392069
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-Phenoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152586; phenoxybenzamide; SCHEMBL5724; Oprea1_299741; CTK9A2463; DTXSID50391112; ZINC2774449; BDBM50392084; STK127625; AKOS003282685; MCULE-1503641736; DA-03295; FT-0766665; ST50721718
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-(3-Benzamidophenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152606; BDBM50392104
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-(2-Carbamoylanilino)phenyl]piperidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152598; BDBM50392096
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
6-Chloro-N-ethyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL177487; ChemDiv3_003219; Cambridge id 5650363; Oprea1_166042; MLS000724132; SCHEMBL15353959; HMS1482C07; HMS2643M05; HMS3429G09; BDBM50178771; MCULE-5400502615; IDI1_021129; SMR000305727; MLS000724132-02; SR-01000490076; SR-01000490076-1; BRD-A90560291-001-01-7
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
2-(4-Acetamidophenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152595; BDBM50392093
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[1-(2-Cyclopentylethyl)-1H-1,2,3-triazole-4-yl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3236132; A1B11; 2-{3-[1-(2-Cyclopentyl-ethyl)-1H-[1,2,3]triazol-4-yl]-phenylamino}-benzamide; BDBM50004135; ZINC169312798
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[43] | |||
| Compound Name |
5-[[3-[(4-Thiophen-2-ylbenzoyl)amino]phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805479; SCHEMBL18340667; BDBM50168493
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[13] | |||
| Compound Name |
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL171955; 6-chloro-1,2,3,4,9-pentahydro-4aH-carbazolecarboxylic acid; TimTec1_007385; Oprea1_389790; SCHEMBL1674922; CTK7I8848; HMS1554P15; 1H-Carbazole-1-carboxylic acid, 6-chloro-2,3,4,9-tetrahydro-; 4476AE; BDBM50178779; MFCD01819788; SBB014570; STK697946; AKOS000507068; AKOS016323550; MCULE-6449178331; AS-70619; ST061441; CS-0060779; FT-0698489; SR-01000370158; SR-01000370158-1; F3308-2726; 6-Chloro-1,2,3,4-tetrahydro-9H-carbazole-1-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
N-[1-(5-Carbamoyl-3-pyridyloxy)-5-naphthyl]-3-nitro-4-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3343651; BDBM50030107
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[18] | |||
| Compound Name |
N-(4-Bromopyridine-3-yl)-3-(naphthalene-2-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3358391; BDBM50041529
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
6-Bromo-2,3,4,9-tetrahydro-1H-beta-carboline-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL372574; BDBM50178778
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
2-[3-(3-Fluorophenethyloxy)phenylamino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152621; 2-{3-(3-fluorophenethyloxy)phenylamino}benzamide; SCHEMBL16011487; BDBM50392055; 2-[3-[2-(3-fluorophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-Anilino-N,N-dimethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152585; ARONIS26399; BDBM50392083; STL256943; ZINC32814984; AKOS005278786; N,N-dimethyl-2-(phenylamino)benzamide; MCULE-9310392359; KS-00004819
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4170094
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449710; L5C
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[44] | |||
| Compound Name |
2-[4-(Phenylcarbamoyl)anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152592; BDBM50392090
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-((2-Methoxynaphthalen-1-yl)methyl)-7-((pyridin-3-ylmethyl)amino)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3h)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ICL-SIRT078; CHEMBL3769975; SCHEMBL17713120; BDBM50148827
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
6-Chloro-2,3,4,4a,9,9a-hexahydro-1H-carbazole-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL382277; SCHEMBL18134580; BDBM50178783
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
2-[3-[2-[4-(Trifluoromethyl)phenyl]ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152620; BDBM50392053
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(4-Bromophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152628; BDBM50392062
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Phenethylphenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152590; BDBM50392088
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Phenoxyphenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562474; BDBM50392079; ZINC43120111
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4227437
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MZ-242; BDBM50459845
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[41] | |||
| Compound Name |
N-[4-(2-Carbamoylanilino)phenyl]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152599; BDBM50392097
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Methoxyanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152576; 2-(4-Methoxyphenylamino)Benzamide; SCHEMBL6443532; CTK0E6090; DTXSID20542497; BDBM50392073; Benzamide, 2-[(4-methoxyphenyl)amino]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-((3-Phenethoxyphenyl)Amino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152613; 2-[[3-(2-Phenylethoxy)phenyl]amino]benzamide; SCHEMBL17713131; 2-(3-phenethoxyphenylamino)benzamide; BDBM50392111; 2-[3-(Phenethyloxy)phenylamino]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Methyl 4-(2-Carbamoylphenylamino)Benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152579; BDBM50392076
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(4-Fluorophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152622; BDBM50392056
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-[2-(Trifluoromethyl)phenyl]ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152618; BDBM50392116
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(4-Methylphenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152617; BDBM50392115
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[Benzoyl(methyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152607; BDBM50392105
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[4-[(Z)-2-Phenylethenyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152588; BDBM50392086
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[4-[(E)-2-Phenylethenyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152589; BDBM50392087
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-(Furan-2-yl)-6-(1-phenoxypropyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3311079; BDBM50044804; STL099097; AKOS000746286; AKOS025262312; MCULE-2742441113; AO-365/43300823; 1-[3-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]propyl phenyl ether
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
N-(2-Amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL171145; Cambridge id 6804586; Oprea1_158779; MLS000039197; SCHEMBL16266066; HMS2431F20; BDBM50178781; STK697956; AKOS005521237; MCULE-4910466792; SMR000036784; ST032574; AB00119827-01; SR-01000501014; SR-01000501014-1; N-(2-Amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide #; N-(carbamoylmethyl)(6-chloro(1,2,3,4,9-pentahydro-4aH-carbazolyl))carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
2-[3-[2-(2-Chlorophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152623; BDBM50392057
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[(2-Phenylacetyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152608; BDBM50392106
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
5-(2-Methyl-5-octyl-3,4-dihydro-1H-pyrido[4,3-b]indol-8-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408833; SCHEMBL16978496; BDBM50070593
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
3-Anilinobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3915417; SCHEMBL3094251; BDBM50193047; SR-01000655804; SR-01000655804-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-Benzyl-8-(3-methylphenyl)-5-octyl-3,4-dihydro-1H-pyrido[4,3-b]indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408830; SCHEMBL16978500; BDBM50070581
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
2-[3-(Benzylcarbamoyl)anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152604; BDBM50392102
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(4-Chlorophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152625; BDBM50392059
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4225505
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50459843
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
2-[4-[Methyl(phenyl)carbamoyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152591; BDBM50392089
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(3-Methylphenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152616; BDBM50392114
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[2-(2-Fluorophenyl)ethoxy]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2151055; BDBM50392054
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[3-[Methyl(phenyl)carbamoyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152603; BDBM50392101
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-[4-[Benzoyl(methyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152593; BDBM50392091
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Sirt2-PROTAC-1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PROTAC Sirt2 Degrader-1; CHEMBL4225467; BDBM50459841; HY-103636; CS-0028486
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
Ethyl 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL171137; Oprea1_272412; Oprea1_834459; MLS000711887; SCHEMBL4725046; CTK4J1758; DTXSID10387798; HMS2643P09; KS-000025DR; BDBM50178770; ETHYL6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXYLATE; MFCD02766766; STK697949; 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid ethyl ester; AKOS000507083; AKOS016340206; GA-0859; MCULE-7052531585; SMR000281654; A21390; AB00121060-01; SR-01000454882; SR-01000454882-1; 1H-Carbazole-1-carboxylicacid, 6-chloro-2,3,4,9-tetrahydro-, ethyl ester; 1H-Carbazole-1-carboxylicacid,6-chloro-2,3,4,9-tetrahydro-,ethyl ester; 6-Chloro-1,2,3,4-tetrahydro-9H-carbazole-1-carboxylic acid ethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
2-[4-(1-Benzyl-1H-1,2,3-triazole-4-yl)anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3236133; A2B57; 2-[4-(1-Benzyl-1H-[1,2,3]triazol-4-yl)-phenylamino]-benzamide; BDBM50004137; ZINC169312799
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[43] | |||
| Compound Name |
Methyl 3-(2-Carbamoylphenylamino)Benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152568; BDBM50392064
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-[[(5S)-6-[[(2S)-6-Acetamido-1-amino-1-oxohexan-2-yl]amino]-5-[[(2S)-2,6-diacetamidohexanoyl]amino]-6-oxohexyl]carbamothioylamino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3601368; BDBM50106871
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
2-(Naphthalen-2-ylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152582; BDBM50392080
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(6-Methyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)methanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL175365; ChemDiv2_000903; Oprea1_147664; SCHEMBL3676864; CTK0A7068; DTXSID50385899; HMS1371J01; DNDI1416932; BDBM50178777; CCG-19719; AKOS000666463; MCULE-7594754719; 1H-Carbazole-1-methanamine, 2,3,4,9-tetrahydro-6-methyl-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
Ethyl N-[4-[(3-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4090805; BDBM50267627
Click to Show/Hide
|
||||
| Activity |
IC50 = 108700 nM
|
[19] | |||
| Compound Name |
Methyl N-[4-[(3-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104634; BDBM50267654
Click to Show/Hide
|
||||
| Activity |
IC50 = 109900 nM
|
[19] | |||
| Compound Name |
2-Benzoyl-1H-benzo[f]chromen-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797737; 2-benzoyl-1H,2H,3H-naphtho[2,1-b]pyran-3-one; SCHEMBL1710776; BDBM50346539; AKOS002367589; AKOS016327811; MCULE-3084067707; 2-(phenylcarbonyl)benzo[f]chroman-3-one; 2-benzoyl-1,2-dihydrobenzo[f]chromen-3-one; ST50405051; 1,2-Dihydro-2-benzoyl-3H-naphtho[2,1-b]pyran-3-one; F3308-2800
Click to Show/Hide
|
||||
| Activity |
IC50 = 112000 nM
|
[38] | |||
| Compound Name |
5-[[3-[(3-Fluoro-4-phenylbenzoyl)amino]phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805586; SCHEMBL18340239; BDBM50168934
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[13] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-[[2-[[2-[[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]amino]acetyl]amino]acetyl]amino]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3885209; BDBM50209647
Click to Show/Hide
|
||||
| Activity |
IC50 = 116000 nM
|
[23] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-2-[[(2S)-2,6-diacetamidohexanoyl]amino]-6-(propan-2-ylcarbamothioylamino)hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3601365; BDBM50106873
Click to Show/Hide
|
||||
| Activity |
IC50 = 117900 nM
|
[29] | |||
| Compound Name |
3-[(2-Methoxynaphthalen-1-yl)methyl]-7-[(4-methoxyphenyl)methylamino]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4091659; SCHEMBL17723184; BDBM50501455
Click to Show/Hide
|
||||
| Activity |
IC50 = 119400 nM
|
[4] | |||
| Compound Name |
1-[(4-Ethoxyphenyl)methyl]-5-[(2-methoxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219551
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[25] | |||
| Compound Name |
5-[(2-Hydroxynaphthalen-1-yl)methyl]-6-phenyl-1-[(4-propoxyphenyl)methyl]-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219561
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[25] | |||
| Compound Name |
1-[(4-Ethoxyphenyl)methyl]-5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidenepyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3219560
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[25] | |||
| Compound Name |
Tert-butyl N-[4-[(4-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4092171; BDBM50267653
Click to Show/Hide
|
||||
| Activity |
IC50 = 121200 nM
|
[19] | |||
| Compound Name |
(S)-2-((S)-6-Acetamido-2-((S)-2-acetamidopropanamido)hexanamido)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254124; BDBM50326789
Click to Show/Hide
|
||||
| Activity |
IC50 = 122000 nM
|
[36] | |||
| Compound Name |
7-[(3,5-Dimethyl-1,2-oxazol-4-yl)methylamino]-3-[(4-methoxynaphthalen-1-yl)methyl]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4088755; BDBM50501456
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[4] | |||
| Compound Name |
N-[2-[3-(Piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]cyclopentanecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523969; BDBM50428987
Click to Show/Hide
|
||||
| Activity |
EC50 = 130000 nM
|
[20] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-[6-(1,3-benzoxazol-2-ylsulfanyl)hexanoylamino]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883946; BDBM50209635
Click to Show/Hide
|
||||
| Activity |
IC50 = 133100 nM
|
[23] | |||
| Compound Name |
(S)-Benzyl 6-ethanethioamido-1-oxo-1-(phenylamino)hexan-2-ylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL584353; SCHEMBL8079485; BDBM50300464; benzyl N-[(2S)-1-anilino-6-(ethanethioylamino)-1-oxohexan-2-yl]carbamate
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[45] | |||
| Compound Name |
4-[[3-[(5-Carbamoylpyridin-3-yl)oxymethyl]phenyl]carbamoyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805568; SCHEMBL18340130; BDBM50168845
Click to Show/Hide
|
||||
| Activity |
IC50 = 142000 nM
|
[13] | |||
| Compound Name |
N-[3-[(5-Carbamoylpyridin-3-yl)oxymethyl]phenyl]-6-thiophen-2-ylpyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805578; SCHEMBL18339922; BDBM50168930
Click to Show/Hide
|
||||
| Activity |
IC50 = 145000 nM
|
[13] | |||
| Compound Name |
(4-Bromophenyl)(5-hydroxynaphtho[1,2-b]furan-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314707; ZINC983965; BDBM50425978; MCULE-7954543364; AI-031/43090787
Click to Show/Hide
|
||||
| Activity |
IC50 = 146000 nM
|
[32] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-2-[[(2S)-2,6-diacetamidohexanoyl]amino]-6-[[2-[[5-[(E)-2-phenylethenyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884953; BDBM50209646
Click to Show/Hide
|
||||
| Activity |
IC50 = 149500 nM
|
[23] | |||
| Compound Name |
3-[[3-(Tert-Butoxycarbonylamino-phenyl)-1,2,4-oxadiazole-5-carbonyl]amino]-1-(4-(trifluoromethyl)phenyl)thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469018; BDBM50261821
Click to Show/Hide
|
||||
| Activity |
IC50 = 168000 nM
|
[46] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-[(2-benzylsulfanylacetyl)amino]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884070; BDBM50209642
Click to Show/Hide
|
||||
| Activity |
IC50 = 171000 nM
|
[23] | |||
| Compound Name |
(2,5-Dihydroxyphenyl)(5-hydroxy-1-benzofuran-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314710; Oprea1_176763; ZINC54918; HMS1618E01; BDBM50425971; STK662503; AKOS003827106; MCULE-8665468584; ST002292; EU-0017163; SR-01000115076; SR-01000115076-1; 2,5-dihydroxyphenyl 5-hydroxybenzo[b]furan-3-yl ketone
Click to Show/Hide
|
||||
| Activity |
Ki = 174400 nM
|
[32] | |||
| Compound Name |
Chembl4287164
Click to Show/Hide
|
Investigative | Compound Info | ||
| Activity |
IC50 = 177800 nM
|
[30] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-[6-(1H-benzimidazol-2-ylsulfanyl)hexanoylamino]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884314; BDBM50209650
Click to Show/Hide
|
||||
| Activity |
IC50 = 187300 nM
|
[23] | |||
| Compound Name |
1-[[3-(4-Tert-butylphenyl)-1,2,4-oxadiazole-5-carbonyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL512966; SCHEMBL2542137; BDBM50261974; CCG-42491; SR-01000632487-1; 3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[3-trifluoromethylphenyl]thiourea
Click to Show/Hide
|
||||
| Activity |
IC50 = 192000 nM
|
[46] | |||
| Compound Name |
5-[[3-[(2-Methylbenzoyl)amino]phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805997; SCHEMBL18340661; BDBM50168732
Click to Show/Hide
|
||||
| Activity |
IC50 = 192000 nM
|
[13] | |||
| Compound Name |
5-[[3-(Naphthalene-1-carbonylamino)phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805381; SCHEMBL18340146; BDBM50168832
Click to Show/Hide
|
||||
| Activity |
IC50 = 192000 nM
|
[13] | |||
| Compound Name |
3-(4-Fluorophenyl)benzofuran-4,6-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1740984; CHEMBL3698626; BDBM131034; 3-(4-fluorophenyl)-1-benzofuran-4,6-diol; US8835659, 19
Click to Show/Hide
|
||||
| Activity |
IC50 = 192000 nM
|
[33] | |||
| Compound Name |
Methanone, (4,6-dibromo-5-hydroxy-3-benzofuranyl)phenyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314702; ACMC-20lcpc; Oprea1_229127; C15H8Br2O3; CBDivE_008921; CTK3A7868; DTXSID80360977; ZINC977853; BDBM50425984; STK833418; AKOS005623391; MCULE-7702332774; 4,6-Dibromo-3-benzoyl-5-hydroxybenzofuran; (4,6-dibromo-5-hydroxy-1-benzofuran-3-yl)(phenyl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 198000 nM
|
[32] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 54 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
US9359293, TM
Click to Show/Hide
|
Patented | Compound Info | ||
| Synonyms |
SCHEMBL18103197; CHEMBL3940508; BDBM234208; US9359293, TM
Click to Show/Hide
|
||||
| Activity |
IC50 > 205000 nM
|
[47] | |||
| Compound Name |
5-[[3-(Adamantane-1-carbonylamino)phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3806274; SCHEMBL18340336; BDBM50168839
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
1-(6-Chloro-2,2-dimethyl-3,4-dihydrochromen-4-yl)-3-(4-nitrophenyl)thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL608379; BDBM50267661
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[19] | |||
| Compound Name |
4-[(6-Bromo-2-hydroxynaphthalen-1-yl)methyl]-3-(4-methylphenyl)-2H-1,2-oxazol-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233749; BDBM50004887
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
Tert-butyl N-[2,2-dimethyl-4-[(3-nitrophenyl)carbamoylamino]-3,4-dihydrochromen-6-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4084417; BDBM50267648
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[19] | |||
| Compound Name |
5-[(3-Acetamidophenyl)methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805923; SCHEMBL18339866; BDBM50168841
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
5-[[3-[(4-Phenoxybenzoyl)amino]phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3804901; SCHEMBL18340495; BDBM50168851
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
(s)-8-Bromo-6-chloro-2-pentylchroman-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2164016; SCHEMBL17389374; BDBM50395320; (2S)-8-bromo-6-chloro-2-pentyl-2,3-dihydrochromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[8] | |||
| Compound Name |
5-[[3-[(4-Phenylmethoxybenzoyl)amino]phenyl]methoxy]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3806073; SCHEMBL18339833; BDBM50168871
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
Chembl4128509
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276139
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[40] | |||
| Compound Name |
Chembl4128353
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276141
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[40] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-2-[[(2S)-2,6-diacetamidohexanoyl]amino]-6-[[2-[(2-iodoacetyl)amino]acetyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884524; BDBM50209632
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[23] | |||
| Compound Name |
2-(3-Cyclohexylmethoxyphenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152610; BDBM50392108
Click to Show/Hide
|
||||
| Activity |
IC50 = 210000 nM
|
[16] | |||
| Compound Name |
(S)-Methyl 2-((S)-2-((S)-2-acetamidopropanamido)-6-pivalamidohexanamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254218; BDBM50326791
Click to Show/Hide
|
||||
| Activity |
IC50 = 223000 nM
|
[36] | |||
| Compound Name |
N-[4-(Imidazol-1-ylmethyl)phenyl]-2,4-dioxo-1H-quinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622695; SCHEMBL16179458; BDBM50123357; ZINC19334956; AKOS026699891; F9994-0201; N-(4-((1H-imidazol-1-yl)methyl)phenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; N-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 238000 nM
|
[49] | |||
| Compound Name |
(4-Bromophenyl)(5-hydroxy-1-benzofuran-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS001178337; SMR000476405; (4-bromophenyl)-(5-hydroxy-1-benzofuran-3-yl)methanone; cid_900927; CHEMBL1711590; BDBM69620; HMS2807C11; ZINC480016; ALBB-031444; MFCD05739936; AKOS030211772; MCULE-3566449334; AI-031/43090788; (4-bromophenyl)-(5-hydroxy-3-benzofuranyl)methanone; (4-bromophenyl)-(5-hydroxybenzofuran-3-yl)methanone; (4-bromophenyl)-(5-oxidanyl-1-benzofuran-3-yl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 240000 nM
|
[32] | |||
| Compound Name |
(4-Bromophenyl)(5-hydroxy-2-methyl-1-benzofuran-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1876771; Oprea1_211879; MLS001178663; HMS2794N14; ZINC446183; SMSF0009609; BDBM50425987; CB01027; MCULE-2971789686; SMR000476346; 2-methyl-3-(4-bromobenzoyl)-5-hydroxybenzofuran; AH-262/32338072
Click to Show/Hide
|
||||
| Activity |
IC50 = 243000 nM
|
[32] | |||
| Compound Name |
CID 72550747
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408820; BDBM50070589; 2-methyl-8-(4-methylsulfonylphenyl)-5-octyl-3,4-dihydro-1H-pyrido[4,3-b]indole
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[21] | |||
| Compound Name |
(5-Hydroxynaphtho[1,2-b]furan-3-yl)(4-methoxyphenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314708; Oprea1_545886; CBDivE_004493; SCHEMBL299172; ZINC190308; (5-hydroxybenzo[g][1]benzofuran-3-yl)-(4-methoxyphenyl)methanone; BDBM50425977; STK832924; AKOS005623145; CCG-238258; MCULE-1311669060; ST51001143; AH-262/01721029; 5-hydroxynaphtho[1,2-b]furan-3-yl 4-methoxyphenyl ketone; (5-Hydroxy-naphtho[1,2-b]furan-3-yl)-(4-methoxyphenyl)-methanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 256000 nM
|
[32] | |||
| Compound Name |
(S)-Methyl 2-((S)-6-acetamido-2-((S)-2-acetamidopropanamido)hexanamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254125; BDBM50326790
Click to Show/Hide
|
||||
| Activity |
IC50 = 268000 nM
|
[36] | |||
| Compound Name |
3-(3,5-Difluorophenyl)-1-benzofuran-4,6-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4,6-Benzofurandiol,3-(3,5-difluorophenyl)-; SCHEMBL1743347; CHEMBL3698625; BDBM131033; US8835659, 16
Click to Show/Hide
|
||||
| Activity |
IC50 = 274000 nM
|
[33] | |||
| Compound Name |
(2S)-N-[(2S)-6-Acetamido-1-amino-1-oxohexan-2-yl]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814816; BDBM50350511
Click to Show/Hide
|
||||
| Activity |
IC50 = 290000 nM
|
[50] | |||
| Compound Name |
(2,5-Dimethoxyphenyl)(5-hydroxy-1-benzofuran-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000105566; SMR000102447; (2,5-dimethoxyphenyl)-(5-hydroxy-1-benzofuran-3-yl)methanone; CHEMBRDG-BB 5169029; Opera_ID_347; Cambridge id 5169029; TimTec1_000152; Oprea1_271947; CBDivE_006194; MLS002539611; cid_626866; CHEMBL1483738; BDBM42882; CTK4D3441; ZINC36645; DTXSID30347859; HMS1534G20; HMS2392G17; STK013175; AKOS001717397; MCULE-7819520764; ST001882; UNM000006123802; AB00074803-01; SR-01000437678; SR-01000437678-1; BRD-K23310481-001-01-7; 2,5-dimethoxyphenyl 5-hydroxybenzo[b]furan-3-yl ketone; (2,5-Dimethoxyphenyl)(5-hydroxybenzofuran-3-yl)methanone; (2,5-dimethoxyphenyl)-(5-hydroxy-3-benzofuranyl)methanone; (2,5-dimethoxyphenyl)-(5-hydroxybenzofuran-3-yl)methanone; Methanone, (5-hydroxy-3-benzofuryl)(2,5-dimethoxyphenyl)-; (2,5-Dimethoxyphenyl)(5-hydroxy-1-benzofuran-3-yl)methanone #; (2,5-dimethoxyphenyl)-(5-oxidanyl-1-benzofuran-3-yl)methanone; (2,5-dimethoxyphenyl)(5-hydroxy-1-benzo[b]furan-3-yl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
(5-Hydroxynaphtho[1,2-b]furan-3-yl)(phenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314704; 3-Benzoylnaphtho[1,2-b]furan-5-ol; CBDivE_011412; (5-hydroxybenzo[g][1]benzofuran-3-yl)-phenylmethanone; ZINC285569; BDBM50425981; STL340319; AKOS022139816; MCULE-8240933052; AH-262/34334033
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
Chembl4129734
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276142
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[40] | |||
| Compound Name |
2-(3-Benzyloxyphenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152612; BDBM50392110
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[16] | |||
| Compound Name |
[5-Hydroxy-4-(4-morpholinylmethyl)-1-benzofuran-3-yl](phenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1618862; Oprea1_292700; AH-262/34641031; BDBM50425986; STL325282; ZINC19774995; AKOS022140102; MCULE-4561024160; [5-hydroxy-4-(morpholin-4-ylmethyl)-1-benzofuran-3-yl](phenyl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
3-Benzoyl-1-benzofuran-5-yl acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS001179149; SMR000476349; (3-benzoyl-1-benzofuran-5-yl) acetate; CBMicro_042380; Oprea1_664536; cid_878744; CHEMBL1882210; BDBM69626; HMS2781A08; ZINC448375; MCULE-5394150943; BIM-0042384.P001; acetic acid (3-benzoyl-5-benzofuranyl) ester; acetic acid (3-benzoylbenzofuran-5-yl) ester; [3-(phenylcarbonyl)-1-benzofuran-5-yl] ethanoate; AH-262/33701022; SR-01000226099; SR-01000226099-1
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
3-(2,5-Dimethoxybenzoyl)-1-benzofuran-5-yl acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000702482; SMR000226432; Oprea1_598943; cid_867287; [3-(2,5-dimethoxybenzoyl)-1-benzofuran-5-yl] acetate; CHEMBL1332714; BDBM69064; HMS2595A18; HMS3380H16; ZINC431649; MCULE-9796648037; SR-01000209971; SR-01000209971-1; [3-(2,5-dimethoxyphenyl)carbonyl-1-benzofuran-5-yl] ethanoate; acetic acid [3-(2,5-dimethoxybenzoyl)benzofuran-5-yl] ester; acetic acid [3-[(2,5-dimethoxyphenyl)-oxomethyl]-5-benzofuranyl] ester
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
(2,5-Dimethoxy-phenyl)-(5-hydroxy-4-morpholin-4-ylmethyl-benzofuran-3-yl)-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SMR000010588; MLS000075556; CHEMBL1393757; Oprea1_832225; MLS000889293; cid_645092; BDBM52057; HMS2395H10; STK731282; ZINC19830714; AKOS000507161; MCULE-2580222438; AH-262/08619012; (2,5-dimethoxyphenyl)-[5-hydroxy-4-(morpholinomethyl)benzofuran-3-yl]methanone
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
[4-(Benzyloxy)phenyl](4,6-dibromo-5-hydroxy-1-benzofuran-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314703; Oprea1_758063; AH-262/34641039; ZINC2075271; BDBM50425983; MCULE-6951725778
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
(5-Hydroxynaphtho[1,2-b]furan-3-yl)(4-methylphenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314706; Oprea1_803456; CBDivE_008923; HMS1578P10; ZINC285571; BDBM50425979; STK832506; AKOS005623409; MCULE-8195326859; AH-262/34337057
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
2-(3-Isobutoxyphenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152611; BDBM50392109
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[16] | |||
| Compound Name |
(4,6-Dibromo-5-hydroxy-1-benzofuran-3-yl)(2,5-dimethoxyphenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1903929; Oprea1_596274; CBDivE_006232; MLS001178796; SCHEMBL3377885; HMS2798E05; ZINC978589; BDBM50425982; (4,6-dibromo-5-hydroxy-1-benzofuran-3-yl)-(2,5-dimethoxyphenyl)methanone; MCULE-6088915015; SMR000476352; AH-262/34334029; 4,6-dibromo-3-(2,5-dimethoxybenzoyl)-5-hydroxybenzofuran
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
(4-Bromophenyl)(5-methoxy-2-methylnaphtho[1,2-b]furan-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2314709; ZINC752611; BDBM50425976; STL328235; AKOS022132880; MCULE-5961962821; AH-262/36520035
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[32] | |||
| Compound Name |
N-[4-[[3-[[2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetyl]amino]phenyl]methoxy]phenyl]thiophene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4070149; SCHEMBL20067968; BDBM50242137
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[51] | |||
| Compound Name |
2-[3-(3-Phenylpropoxy)anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152614; BDBM50392112
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[16] | |||
| Compound Name |
2,4-Dioxo-N-(4-(pyridin-3-yloxy)phenyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SIRT6-IN-1; CHEMBL3288034; 2,4-dioxo-N-[4-(pyridin-3-yloxy)phenyl]-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; SCHEMBL16179838; BDBM50017341; ZINC19339902; BRD-K25690991-001-01-3; F1902-0117; Z2037275165
Click to Show/Hide
|
||||
| Activity |
IC50 = 314000 nM
|
[49] | |||
| Compound Name |
3-[[3-(Naphthalen-1-yl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[4-trifluoromethylphenyl]thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466754; BDBM50261757
Click to Show/Hide
|
||||
| Activity |
IC50 = 318000 nM
|
[46] | |||
| Compound Name |
2-(3-(4-Tert-butylphenyl)-1,2,4-oxadiazole-5-carbonyl)-N-(4-(trifluoromethyl)phenyl)hydrazinecarbothioamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466960; BDBM50261975; 3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[4-trifluoromethylphenyl]thiourea
Click to Show/Hide
|
||||
| Activity |
IC50 = 325000 nM
|
[46] | |||
| Compound Name |
2-[[4-(1,3-Dioxoisoindol-2-yl)benzoyl]amino]-5-hydroxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4217987; Oprea1_591707; SCHEMBL4728715; ZINC4823829; BDBM50451276; STK223532; AKOS003264826; MCULE-2189201025; SR-01000250375; SR-01000250375-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 424000 nM
|
[52] | |||
| Compound Name |
2,4-Dioxo-N-[3-(2-pyridin-4-ylethyl)phenyl]-1H-quinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622696; SCHEMBL16179957; BDBM50123364; ZINC19330730; AKOS030459960
Click to Show/Hide
|
||||
| Activity |
IC50 = 424000 nM
|
[49] | |||
| Compound Name |
6-Methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL592963; SCHEMBL4305442; BDBM50304351; PK04_130211; 6-methoxy-1-(3-methoxyprop-1-ynyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Click to Show/Hide
|
||||
| Activity |
IC50 = 570000 nM
|
[35] | |||
| Compound Name |
4-[[4-(Furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4205716; SCHEMBL16179844; ZINC4945036; BDBM50451275; STK292624; AKOS000644917; MCULE-8086974834; 4-[4-(FURAN-2-AMIDO)BENZAMIDO]-2-HYDROXYBENZOIC ACID; 4-[({4-[(furan-2-ylcarbonyl)amino]phenyl}carbonyl)amino]-2-hydroxybenzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 599000 nM
|
[52] | |||
| Compound Name |
Surfactin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
surfactin C; Leu7-Surfactin; CHEMBL508272; SCHEMBL1434743; DTXSID20893274; BDBM50378583; C12043; Q3132229; Surfactin, from Bacillus subtilis, >=98.0% (HPLC)
Click to Show/Hide
|
||||
| Activity |
IC50 > 600000 nM
|
[39] | |||
| Compound Name |
Sirt6-IN-5
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4206619; 5-(4-(Furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid; SCHEMBL16179518; BDBM50451274; STK276510; AKOS005425617; MCULE-7588193558; 5-[4-(FURAN-2-AMIDO)BENZAMIDO]-2-HYDROXYBENZOIC ACID; 5-[[4-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid; 5-[({4-[(furan-2-ylcarbonyl)amino]phenyl}carbonyl)amino]-2-hydroxybenzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 783000 nM
|
[52] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-[6-[(6-amino-7H-purin-8-yl)sulfanyl]hexanoylamino]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884078; BDBM50209648
Click to Show/Hide
|
||||
| Activity |
IC50 > 900000 nM
|
[23] | |||
| Compound Name |
Benzyl N-[(2S)-8-amino-1-anilino-1,8-dioxooctan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3218176
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|
||||
| Activity |
IC50 > 1000000 nM
|
[50] | |||
| Compound Name |
4-Tert-Butylbenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(tert-butyl)benzoic acid; P-TERT-BUTYLBENZOIC ACID; Benzoic acid, 4-(1,1-dimethylethyl)-; Benzoic acid, p-tert-butyl-; 4-t-butylbenzoic acid; 4-tert-Butyl-benzoic acid; 4-tert-Butylbenzoicacid; p-t-Butylbenzoic acid; NSC 4802; UNII-43Z7T3VN0R; Kyselina p-terc.butylbenzoova; CHEMBL93746; 43Z7T3VN0R; 4-(1,1-dimethylethyl)benzoic acid; MFCD00002563; Benzoic acid, 4-tert-butyl-; HSDB 5321; EINECS 202-696-3; Kyselina p-terc.butylbenzoova [Czech]; BRN 0607545; AI3-28522; CCRIS 9443; p-t-butyl benzoic acid; PubChem19991; p-sec-Butylbenzoic acid; 4-t-butyl benzoic acid; 4-tert -butylbenzoic acid; 4-tert-butyl benzoic acid; p-(t-butyl)-benzoic acid; para-tert-butylbenzoic acid; EC 202-696-3; 4-tertiary-butylbenzoic acid; ACMC-1BP63; DSSTox_CID_20703; DSSTox_RID_79554; DSSTox_GSID_40703; SCHEMBL36693; 4-(tert-butyl)-benzoic acid; 4-~{tert}-butylbenzoic acid; 4-09-00-01884 (Beilstein Handbook Reference); BIDD:ER0699; Benzoic acid,1-dimethylethyl)-; DTXSID0040703; 4-tert-Butylbenzoic acid, 99%; KS-00000VUH; NSC4802; P-Tert-Butylbenzoic Acid, 99%; BENZOIC ACID,4-TERT.BUTYL; ZINC388305; NSC-4802; Tox21_301337; ANW-40955; BDBM50405320; SBB040518; STK724072; p-tert-Butylbenzoic acid (P-TBBA); AKOS000160810; BS-3966; CM12555; CS-W017327; MCULE-5279293567; WLN: QVR XX1 & 1 & 1; NCGC00164066-01; NCGC00255598-01; AC-10999; AK-44159; BR-44159; SC-23348; AM20060764; B0717; BB 0221132; FT-0619495; ST50213867; C14535; M-5881; Q2823226; W-100065; F2191-0110; Z256708702; UNII-UGL7Q68L1S component KDVYCTOWXSLNNI-UHFFFAOYSA-N; p-tert-Butylbenzoic acid-Benzoic acid, 4-(1,1-dimethylethyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[53] | |||
| Compound Name |
5-(3-(Furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
OSS_128167; OSS-128167; CHEMBL1588664; MLS001208603; SCHEMBL16179714; HMS2819N24; BCP28960; EX-A3569; ZINC4945038; 5-[[3-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid; 5-{3-[(Furan-2-carbonyl)-amino]-benzoylamino}-2-hydroxy-benzoic acid; BDBM50017342; OSS128167; s8627; STK292625; AKOS000644951; CCG-268237; OSS-128167(SIRT6-IN-1); BS-17805; SMR000525099; HY-107454; CS-0028514; 5-[3-(furan-2-amido)benzamido]-2-hydroxybenzoic acid; F1905-7264; OSS 128167; OSS-128167; SIRT6-IN-1; 5-[({3-[(furan-2-ylcarbonyl)amino]phenyl}carbonyl)amino]-2-hydroxybenzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 1578000 nM
|
[52] | |||
| Compound Name |
(S)-Methyl 2-((S)-2-((S)-2-acetamidopropanamido)-6-(2-bromoacetamido)hexanamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1255034; BDBM50326792
Click to Show/Hide
|
||||
| Activity |
IC50 = 1767000 nM
|
[36] | |||
| Compound Name |
4-(3-{[Amino(phenylimino)methyl]sulfanyl}-2,5-dioxo-1-pyrrolidinyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3288044; BDBM50017344; STK372656; AKOS000583963; AKOS022014134; MCULE-1337998480; ST007178; 4-[3-((1E)-1-amino-2-phenyl-2-azavinylthio)-2,5-dioxoazolidinyl]benzoic acid; 4-{2,5-dioxo-3-[(N'-phenylcarbamimidoyl)sulfanyl]pyrrolidin-1-yl}benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 3466000 nM
|
[54] | |||
| Compound Name |
1,3-Dimethyl-2,4-dioxo-N-[4-(pyridin-4-ylmethyl)phenyl]quinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623254; 1,3-dimethyl-2,4-dioxo-N-[4-(pyridin-4-ylmethyl)phenyl]-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; ZINC1069449; BDBM50123399; STK665401; AKOS003404699; MCULE-8902652642; ST056684; 1,3-dimethyl-6-({[4-(4-pyridylmethyl)phenyl]amino}sulfonyl)-1,3-dihydroquinazo line-2,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 6521000 nM
|
[49] | |||
| Compound Name |
N-[(3-Pyridin-3-yl-1H-1,2,4-triazol-5-yl)methyl]pyrazine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3288043; SCHEMBL16511175; BDBM50017343; SR-01000335214; SR-01000335214-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 1470000000 nM
|
[54] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 44 | X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells. Eur J Med Chem. 2018 Jul 15;155:806-823. | ||||
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| REF 51 | Discovery of 2-((4,6-dimethylpyrimidin-2-yl)thio)-N-phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors. Eur J Med Chem. 2017 Jul 7;134:230-241. | ||||
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| REF 54 | Discovery of novel and selective SIRT6 inhibitors. J Med Chem. 2014 Jun 12;57(11):4796-804. | ||||
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