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| Protein General Information |
Top |
| Full Name |
NEDD8-conjugating enzyme Ubc12 (UBE2M)
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| UniProt ID |
UBC12_HUMAN
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| Gene Name |
UBE2M
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| Gene ID |
9040
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| References |
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| REF 1 |
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity. Cell. 2004 Jul 9;118(1):83-97.
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| REF 2 |
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. Nat Struct Mol Biol. 2004 Oct;11(10):927-35.
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| REF 3 |
Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases. J Biol Chem. 2006 Aug 4;281(31):21640-51.
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